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  1. Article ; Online: Association between rapid renal function deterioration and cancer mortality in the elderly: A retrospective cohort study.

    Kuo, I-Ching / Chu, Yi-Chi / Chen, Yen-Hsu / Chan, Ta-Chien

    Cancer medicine

    2023  Volume 12, Issue 8, Page(s) 10008–10019

    Abstract: Background: Kidney function is associated with clinical outcomes in patients with cancer.: Objectives: This study aimed to assess the association between kidney function decline and cancer-related mortality among community-dwelling elderly ... ...

    Abstract Background: Kidney function is associated with clinical outcomes in patients with cancer.
    Objectives: This study aimed to assess the association between kidney function decline and cancer-related mortality among community-dwelling elderly individuals.
    Design: This was a retrospective longitudinal cohort study.
    Participants: The 61,988 participants were from an elderly health examination database in Taipei City from 2005 to 2012.
    Measurements: Multivariable logistic regression was used to assess the association between baseline covariates and rapidly deteriorating estimated glomerular filtration rate (eGFR). In addition, Cox proportional hazards model and the Fine-Gray model were used to quantify the effects of covariates on total cancer mortality and six specific cancer mortalities.
    Results: During the follow-up period, 1482 participants died of cancer. Their baseline average eGFR was 73.8 ± 19.9 mL/min/1.73 m
    Conclusions: Elderly individuals with rapid kidney function decline had higher cancer mortality risks. Serial assessments of dynamic changes in eGFR might provide information relevant for cancer prognosis.
    MeSH term(s) Male ; Humans ; Aged ; Retrospective Studies ; Longitudinal Studies ; Glomerular Filtration Rate ; Hypertension ; Kidney/physiology ; Risk Factors ; Disease Progression ; Neoplasms
    Language English
    Publishing date 2023-03-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2659751-2
    ISSN 2045-7634 ; 2045-7634
    ISSN (online) 2045-7634
    ISSN 2045-7634
    DOI 10.1002/cam4.5735
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Impact of Plastic-Wrap Properties and Cleaning Intervals on the Disinfection of Elevator Buttons.

    Kuo, Shin-Huei / Liu, Tzu-Yin / Chen, Tun-Chieh / Yang, Chih-Jen / Chen, Yen-Hsu

    International journal of environmental research and public health

    2023  Volume 20, Issue 2

    Abstract: Fomite transmission is a possible route by which different pathogens spread within facilities. In hospital settings, elevator buttons are widely observed to be covered with various types of plastic wraps; however, limited information is available ... ...

    Abstract Fomite transmission is a possible route by which different pathogens spread within facilities. In hospital settings, elevator buttons are widely observed to be covered with various types of plastic wraps; however, limited information is available concerning the impact of different plastic materials on cleaning. Our study aimed to identify which plastic material is suitable for the coverage of elevator buttons and the optimal intervals for their cleaning. We tested six plastic covers, including polyethylene (PE), polymethylpentene (PMP), polyvinyl chloride (PVD), and polyvinylidene chloride (PVDC) plastic wraps; a thermoplastic polyurethane (TPU) keyboard cover; and a polyethylene terephthalate-ethylene vinyl acetate (PET-EVA) laminating film, which are plastic films. The bioburden on the elevator buttons at different time intervals was measured using an adenosine triphosphate (ATP) bioluminescence assay. Our results show that wraps made of PVDC had superior durability compared with those of PMP, PVC, and PVDC, in addition to the lowest detectable ATP levels among the six tested materials. Regarding different button locations, the highest ATP values were found in door-close buttons followed by door-open, and first-floor buttons after one- and three-hour intervals (p = 0.024 and p < 0.001, respectively). After routine disinfection, the ATP levels of buttons rapidly increased after touching and became more prominent after three hours (p < 0.05). Our results indicate that PVDC plastic wraps have adequate durability and the lowest residual bioburden when applied as covers for elevator buttons. Door-close and -open buttons were the most frequently touched sites, requiring more accurate and precise disinfection; therefore, cleaning intervals of no longer than three hours may be warranted.
    MeSH term(s) Disinfection ; Elevators and Escalators ; Polyethylene ; Adenosine Triphosphate
    Chemical Substances Polyethylene (9002-88-4) ; polyvinylidene chloride (9002-85-1) ; Adenosine Triphosphate (8L70Q75FXE)
    Language English
    Publishing date 2023-01-16
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20021649
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  3. Article ; Online: In Reference to Anosmia and Ageusia: Common Findings in COVID-19 Patients.

    Chang, Yang-Pei / Yang, Chih-Jen / Chen, Yen-Hsu

    The Laryngoscope

    2020  Volume 130, Issue 11, Page(s) E694

    MeSH term(s) Ageusia/diagnosis ; Ageusia/epidemiology ; Ageusia/etiology ; Anosmia ; COVID-19 ; Humans ; Olfaction Disorders/diagnosis ; Olfaction Disorders/epidemiology ; Olfaction Disorders/etiology ; Pandemics ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-16
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.28754
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  4. Article ; Online: The preventive strategies of community hospital in the battle of fighting pandemic COVID-19 in Taiwan.

    Yang, Chih-Jen / Chen, Tun-Chieh / Chen, Yen-Hsu

    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

    2020  Volume 53, Issue 3, Page(s) 381–383

    MeSH term(s) Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Health Personnel ; Health Policy ; Hospitals, Community ; Humans ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Information Dissemination ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; Public Health ; Quarantine ; SARS-CoV-2 ; Taiwan/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-03-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1497590-7
    ISSN 1995-9133 ; 1684-1182 ; 0253-2662
    ISSN (online) 1995-9133
    ISSN 1684-1182 ; 0253-2662
    DOI 10.1016/j.jmii.2020.03.019
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  5. Article ; Online: A rare patient with primary endogenous Aspergillus endophthalmitis.

    Chiu, Yu-Yao / Chen, Yen-Hsu / Hsiao, Hui-Hua / Du, Jeng-Shiun

    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

    2021  Volume 54, Issue 3, Page(s) 538–539

    MeSH term(s) Aged ; Antifungal Agents/therapeutic use ; Aspergillosis/complications ; Aspergillosis/diagnosis ; Aspergillosis/drug therapy ; Aspergillosis/immunology ; Aspergillus flavus/drug effects ; Aspergillus flavus/isolation & purification ; Endophthalmitis/diagnosis ; Endophthalmitis/drug therapy ; Endophthalmitis/etiology ; Endophthalmitis/immunology ; Eye Infections, Fungal/complications ; Eye Infections, Fungal/diagnosis ; Eye Infections, Fungal/drug therapy ; Eye Infections, Fungal/immunology ; Fatal Outcome ; Humans ; Immunocompromised Host ; Male
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2021-01-06
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 1497590-7
    ISSN 1995-9133 ; 1684-1182 ; 0253-2662
    ISSN (online) 1995-9133
    ISSN 1684-1182 ; 0253-2662
    DOI 10.1016/j.jmii.2020.12.014
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  6. Article: Genetic Association Studies of

    Faridah, Imaniar Noor / Dania, Haafizah / Maliza, Rita / Chou, Wan-Hsuan / Wang, Wen-Hung / Chen, Yen-Hsu / Perwitasari, Dyah Aryani / Chang, Wei-Chiao

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 21

    Abstract: Dengue is an arboviral disease that has spread globally and become a major public health concern. A small proportion of patients may progress from symptomatic dengue fever (DF) to dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). Findings ... ...

    Abstract Dengue is an arboviral disease that has spread globally and become a major public health concern. A small proportion of patients may progress from symptomatic dengue fever (DF) to dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). Findings from a previous genome-wide association study (GWAS) demonstrated that variations in the major histocompatibility complex (MHC) class I chain-related B (
    Language English
    Publishing date 2023-11-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13213365
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  7. Article ; Online: Obesity as a clinical predictor for severe manifestation of dengue: a systematic review and meta-analysis.

    Chen, Chao-Ying / Chiu, Yu-Yao / Chen, Yu-Cheng / Huang, Chung-Hao / Wang, Wen-Hung / Chen, Yen-Hsu / Lin, Chun-Yu

    BMC infectious diseases

    2023  Volume 23, Issue 1, Page(s) 502

    Abstract: Background: Severe dengue often leads to poor clinical outcomes and high mortality; as a result, it is of vital importance to find prognostic factors associated with the severe form of dengue. Obesity is known to deteriorate many infectious diseases due ...

    Abstract Background: Severe dengue often leads to poor clinical outcomes and high mortality; as a result, it is of vital importance to find prognostic factors associated with the severe form of dengue. Obesity is known to deteriorate many infectious diseases due to impaired immune responses. Several studies have suggested that obese patients with dengue infection tend to have more severe manifestations with poorer prognosis. However, a firm conclusion could not be drawn due to the varied results of these studies. Here, we aimed to conduct a systematic review and meta-analysis to investigate the association between obesity and dengue severity.
    Methods: A literature search for relevant studies was conducted in PubMed, Embase, Ovid Medline and Cochrane from inception to September 9, 2022. The two main keywords were "dengue" and "obesity". Mantel-Haenszel method and random effects model was used to analyze the pooled odds ratio with 95% confidence intervals.
    Results: A total of 15 article involving a total of 6,508 patients were included in the meta-analysis. Included patients in most studies were hospitalized pediatric patients. Only one study included adulthood data. Three cohort studies, four case-control studies, and one cross-sectional studies found a significant association between obesity and dengue severity. In contrast, three cohort studies, three case-control studies, and one cross-sectional study reported no significant relationship between obesity and dengue severity. Our analysis results showed that patient with obesity is 50% (OR = 1.50; 95%CI: 1.15-1.97) more likely to develop severe manifestation of dengue.
    Conclusion: This meta-analysis revealed that overweight could be a clinical predictor for severe disease for pediatric patients with dengue infection.
    MeSH term(s) Humans ; Child ; Adult ; Cross-Sectional Studies ; Obesity/complications ; Severe Dengue/complications ; Severe Dengue/diagnosis ; Odds Ratio ; Case-Control Studies
    Language English
    Publishing date 2023-07-31
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2041550-3
    ISSN 1471-2334 ; 1471-2334
    ISSN (online) 1471-2334
    ISSN 1471-2334
    DOI 10.1186/s12879-023-08481-9
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  8. Article ; Online: Decline in invasive pneumococcus diseases while combating the COVID-19 pandemic in Taiwan.

    Tsai, Jong-Rung / Yang, Chih-Jen / Huang, Wei-Ling / Chen, Yen-Hsu

    The Kaohsiung journal of medical sciences

    2020  Volume 36, Issue 7, Page(s) 572–573

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Disinfection ; Hand Disinfection ; Humans ; Masks ; Pandemics/prevention & control ; Patient Isolation ; Personal Protective Equipment ; Pneumococcal Infections/epidemiology ; Pneumococcal Infections/prevention & control ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; SARS-CoV-2 ; Taiwan/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-05-26
    Publishing country China (Republic : 1949- )
    Document type Letter
    ZDB-ID 639302-0
    ISSN 2410-8650 ; 0257-5655
    ISSN (online) 2410-8650
    ISSN 0257-5655
    DOI 10.1002/kjm2.12233
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  9. Article ; Online: Mitigate risks of medication interruption due to COVID-19 for elderly with chronic diseases.

    Hsiao, Shih-Huai / Chang, Hsiu-Mei / Kang, Ya-Ting / Chen, Yen-Hsu

    The Kaohsiung journal of medical sciences

    2020  Volume 36, Issue 8, Page(s) 661–662

    MeSH term(s) Aged ; COVID-19/epidemiology ; Chronic Disease/drug therapy ; Drug Prescriptions ; Hospitals, Teaching ; Humans ; Pharmacies ; Risk Reduction Behavior ; SARS-CoV-2/physiology ; Withholding Treatment
    Keywords covid19
    Language English
    Publishing date 2020-07-01
    Publishing country China (Republic : 1949- )
    Document type Journal Article
    ZDB-ID 639302-0
    ISSN 2410-8650 ; 0257-5655
    ISSN (online) 2410-8650
    ISSN 0257-5655
    DOI 10.1002/kjm2.12263
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  10. Article ; Online: Iatrogenic Takotsubo Cardiomyopathy Following Overdose Norepinephrine Administration During Percutaneous Coronary Intervention.

    Chen, Yen-Hsu / Lai, Hui-Chin / Lee, Wen-Lieng / Liu, Tsun-Jui

    International heart journal

    2020  Volume 61, Issue 6, Page(s) 1298–1302

    Abstract: Takotsubo cardiomyopathy (TTC) is characterized by reversible ventricular dysfunction induced by endogenous and, occasionally, exogenous catecholamine. We present a report on a patient who developed TTC and cardiogenic shock during percutaneous coronary ... ...

    Abstract Takotsubo cardiomyopathy (TTC) is characterized by reversible ventricular dysfunction induced by endogenous and, occasionally, exogenous catecholamine. We present a report on a patient who developed TTC and cardiogenic shock during percutaneous coronary intervention (PCI) secondary to inadvertent norepinephrine administration. His hemodynamic status and cardiac function were totally restored within 1 week after hemodynamic support using intra-aortic balloon pump without sequela. Thus, TTC should be considered once a patient presents with symptoms mimicking acute coronary syndrome (ACS) after catecholamine administration.
    MeSH term(s) Adrenergic beta-1 Receptor Antagonists/therapeutic use ; Angiotensin II Type 1 Receptor Blockers/therapeutic use ; Bisoprolol/therapeutic use ; Coronary Restenosis/surgery ; Creatine Kinase/blood ; Creatine Kinase, MB Form/blood ; Drug Overdose ; Drug-Eluting Stents ; Echocardiography ; Humans ; Hypotension/drug therapy ; Iatrogenic Disease ; Intra-Aortic Balloon Pumping ; Intraoperative Complications/drug therapy ; Male ; Medication Errors ; Middle Aged ; Norepinephrine/poisoning ; Percutaneous Coronary Intervention ; Recovery of Function ; Shock, Cardiogenic/blood ; Shock, Cardiogenic/chemically induced ; Shock, Cardiogenic/diagnosis ; Shock, Cardiogenic/therapy ; Stents ; Stroke Volume ; Takotsubo Cardiomyopathy/blood ; Takotsubo Cardiomyopathy/chemically induced ; Takotsubo Cardiomyopathy/diagnostic imaging ; Takotsubo Cardiomyopathy/therapy ; Troponin I/blood ; Valsartan/therapeutic use ; Vasoconstrictor Agents/poisoning
    Chemical Substances Adrenergic beta-1 Receptor Antagonists ; Angiotensin II Type 1 Receptor Blockers ; Troponin I ; Vasoconstrictor Agents ; Valsartan (80M03YXJ7I) ; Creatine Kinase (EC 2.7.3.2) ; Creatine Kinase, MB Form (EC 2.7.3.2) ; Norepinephrine (X4W3ENH1CV) ; Bisoprolol (Y41JS2NL6U)
    Language English
    Publishing date 2020-10-28
    Publishing country Japan
    Document type Case Reports ; Journal Article
    ZDB-ID 2187806-7
    ISSN 1349-3299 ; 1349-2365
    ISSN (online) 1349-3299
    ISSN 1349-2365
    DOI 10.1536/ihj.20-118
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