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Article: Temporal Single-Cell Sequencing Analysis Reveals That GPNMB-Expressing Macrophages Potentiate Muscle Regeneration.

Chen, Yu-Fan

Research square

2024

Abstract: Macrophages play a crucial role in coordinating the skeletal muscle repair response, but their phenotypic diversity and the transition of specialized subsets to resolution-phase macrophages remain poorly understood. To address this issue, we induced ... ...

Abstract	Macrophages play a crucial role in coordinating the skeletal muscle repair response, but their phenotypic diversity and the transition of specialized subsets to resolution-phase macrophages remain poorly understood. To address this issue, we induced injury and performed single-cell RNA sequencing on individual cells in skeletal muscle at different time points. Our analysis revealed a distinct macrophage subset that expressed high levels of
Language	English
Publishing date	2024-03-28
Publishing country	United States
Document type	Preprint
DOI	10.21203/rs.3.rs-4108866/v1
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Article ; Online: Get the win-win: Sustainable circular model of 'generation-value-technology' of industrial solid waste management.

Gao, Ming / Chen, Yufan

Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA

2023 Volume 42, Issue 3, Page(s) 191–205

Abstract: The management of industrial solid waste (ISW) and promoting sustainable circular development of the industrial economy is an urgent priority today. Therefore, this article constructs a sustainable circular model of 'generation-value-technology' of ISW ... ...

Abstract	The management of industrial solid waste (ISW) and promoting sustainable circular development of the industrial economy is an urgent priority today. Therefore, this article constructs a sustainable circular model of 'generation-value-technology' of ISW management through the lens of industrial added value (IAV) and technology level. Also, the importance of the role of government is considered in the model. Based on actual data of China, this article simulates the future trend of the model using a system dynamics approach. The chief findings of the study are as follows: (1) under the current policy, China's future industrialization is increasing and the technological level of industrial enterprises is rising, but this is accompanied by a climb in ISW generation. (2) The win-win situation of ISW decrease and IAV increase can be achieved through enhanced information disclosure, technology innovation and government incentives. (3) Government subsidy should be oriented towards supporting technology innovation in industrial enterprises while reducing the proportion of incentives for ISW management results. Based on the results, this study proposes targeted policy implications for government and industrial enterprises.
MeSH term(s)	Solid Waste ; Technology ; Industry ; China ; Industrial Waste ; Waste Management
Chemical Substances	Solid Waste ; Industrial Waste
Language	English
Publishing date	2023-06-30
Publishing country	England
Document type	Journal Article
ZDB-ID	1480483-9
ISSN	1096-3669 ; 1399-3070 ; 0734-242X
ISSN (online)	1096-3669 ; 1399-3070
ISSN	0734-242X
DOI	10.1177/0734242X231184446
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Article ; Online: Multi-agent collaborative model of e-waste recycling.

Gao, Ming / Chen, Yufan

Journal of environmental management

2023 Volume 349, Page(s) 119457

Abstract: E-waste production is exploding as a result of rising demand for electronics and a faster rate of replacement. A crucial, yet unresolved issue is how to encourage cooperation among primary agents in the recycling of e-waste. To examine a multi-agent ... ...

Abstract	E-waste production is exploding as a result of rising demand for electronics and a faster rate of replacement. A crucial, yet unresolved issue is how to encourage cooperation among primary agents in the recycling of e-waste. To examine a multi-agent collaborative model of e-waste recycling among local governments, producers, and consumers, this research employs the techniques of evolutionary games and system dynamics. Evolutionary games are used to analyze the strategy choice results, while system dynamics are adopted to depict the decision-making processes. Overall, we find that rewards and penalties affect the stability and efficiency of the collaborative model of e-waste recycling and that the greater the correlation between the rewards-and-penalties mechanism and the strategies, the more stable the model is. Specifically, the results show that: (1) static rewards-and-penalties mechanism is likely to breed mutants and thus is not conducive to stable cooperation; (2) dynamic rewards-and-penalties mechanism can inhibit the instability of e-waste recycling model, but only 60% of producers are willing to build an e-waste recycling system; (3) dynamic rewards-and-penalties optimizing mechanism can ensure that producers and consumers wholeheartedly work for e-waste recycling consistently without local governments regulation; (4) according to the sensitivity analysis, increasing the amount of rewards and penalties can facilitate faster evolution of collaboration in the e-waste recycling system. Finally, this study makes implications for promoting efficiency and stability in e-waste recycling among local governments, producers, and consumers.
MeSH term(s)	Waste Management/methods ; Electronic Waste ; Recycling/methods ; Electronics
Language	English
Publishing date	2023-10-31
Publishing country	England
Document type	Journal Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2023.119457
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Article ; Online: Misinformation Regarding 5G and COVID-19 and the Psychological Mechanism Behind Them

Chen, Yufan

Advances in Social Science and Culture; Vol 2, No; p56 ; 2640-9674 ; 2640-9682

2020 Volume 4

Abstract: In late 2019, the COVID-19 pandemic started to spread around the world (Fauci, Lane, & Redfield, 2020). Along with the virus, misinformation about the pandemic started to spread as well. Rumors regarding the usefulness of masks, conspiracy theories ... ...

Abstract	In late 2019, the COVID-19 pandemic started to spread around the world (Fauci, Lane, & Redfield, 2020). Along with the virus, misinformation about the pandemic started to spread as well. Rumors regarding the usefulness of masks, conspiracy theories regarding the legitimacy and origin of the virus, and the astonishing amount of fake news about the virus posted online every day are extremely hard to distinguish from factual news reports (Mian & Khan, 2020; Brennan, Simon, Howard, & Nielson, 2020). One example of this alarming phenomenon is the conspiracy theory that links the pandemic to 5G, which is in the early stages of being commercialized (Shafi et al., 2017). This conspiracy theory claims that 5G and the radiation it causes disrupted the natural magnetic field of the earth, and started this pandemic (Geary, 2020). Though it might look like an absurd concept, the “5G causes Corona” conspiracy theory has gained an extremely large following, and the effect of that is clear on and off the internet, as multiple 5G antennas have been vandalized all over the world by mobs claiming they are the means of spreading the coronavirus (Reichert, 2020). The fabrication and spreading of misinformation regarding 5G and its link to the coronavirus are largely connected with the multiple psychological mechanisms and manipulation of sources.
Keywords	covid19
Language	English
Publishing date	2020-10-09
Publisher	SCHOLINK INC.
Document type	Article ; Online
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Article ; Online: Interaction of norfloxacin and hexavalent chromium with ferrihydrite nanoparticles: Synergistic adsorption and antagonistic aggregation behavior.

Chen, Yufan / Li, Zhixiong

Chemosphere

2022 Volume 299, Page(s) 134386

Abstract: The co-existence of hexavalent chromium (Cr(VI)) and norfloxacin (NOR) can be detected in natural environments. However, the interaction of the co-existing Cr(VI), NOR and ferrihydrite nanoparticles (FNPs, a ubiquitous natural iron oxide nanoparticle) is ...

Abstract	The co-existence of hexavalent chromium (Cr(VI)) and norfloxacin (NOR) can be detected in natural environments. However, the interaction of the co-existing Cr(VI), NOR and ferrihydrite nanoparticles (FNPs, a ubiquitous natural iron oxide nanoparticle) is lacking investigation. Figuring out this interaction could help us better predict the transport and fate of the relevant contaminants. Here, the adsorption and aggregation of FNPs in the presence of Cr(VI) and NOR were investigated. Comparing to FNPs interaction with Cr(VI) or NOR alone, the co-existence of Cr(VI) and NOR could lead to a synergistic effect to increase their adsorption onto FNPs. This observation can be attributed to the complexation between Cr(VI) and carboxyl or amino groups from NOR. Furthermore, the aggregation of FNPs could be accelerated by Cr(VI) through charge neutralization since the adsorption of Cr(VI) could decrease the surface potential of FNPs (positive charge). However, the presence of NOR will increase the surface charge, and thus stabilize FNPs. In general, the aggregation state of FNPs in the presence of co-existing Cr(VI) and NOR depends on their ratio. Overall, these understandings help us predict the transport and fate of FNPs and the associated contaminants in natural environments.
MeSH term(s)	Adsorption ; Chromium ; Ferric Compounds ; Nanoparticles ; Norfloxacin ; Water Pollutants, Chemical
Chemical Substances	Ferric Compounds ; Water Pollutants, Chemical ; Chromium (0R0008Q3JB) ; chromium hexavalent ion (18540-29-9) ; ferric oxyhydroxide (87PZU03K0K) ; Norfloxacin (N0F8P22L1P)
Language	English
Publishing date	2022-03-19
Publishing country	England
Document type	Journal Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2022.134386
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Article: Urban Land Expansion Dynamics and Drivers in Peri-Urban Areas of China: A Case of Xiaoshan District, Hangzhou Metropolis (1985–2020)

Chen, Yufan / He, Yong

Land. 2022 Sept. 06, v. 11, no. 9

2022

Abstract: China has seen a transition from impulsive industrial development-driven urban expansion to urban planning and government control since the start of the 21st century. Urban planning attempts to ensure the sustainable development of cities and the ... ...

Abstract	China has seen a transition from impulsive industrial development-driven urban expansion to urban planning and government control since the start of the 21st century. Urban planning attempts to ensure the sustainable development of cities and the rational use of land resources. The dual-track urbanization process does, however, often result in a significant gap between planning and actual development. This paper contends that a comprehensive dual-track urbanization research perspective is better suited for investigating urban sprawl in peri-urban areas in post-reform market economy-active regions. Taking Xiaoshan District, the peri-urban area of Hangzhou, China, as a case study, this research utilizes land use raster data from 1985, 2000, 2010, and 2020 to identify the dynamic changes in urban construction land and examines the driving elements through the logistic regression model. Based on the results, the mechanisms of market-incented and government-controlled impacts on urban expansion are explained. This study aims to (1) analyze the spatial and temporal patterns of Xiaoshan’s urban expansion during 1985–2020; (2) compare the compositional characteristics of three types of urban growth (edge growth, infilling, and leapfrog development) in each phase of Xiaoshan; (3) identify the natural environment, accessibility factors, and socioeconomic aspects that promote Xiaoshan’s urban expansion in 2000–2020; (4) discuss Xiaoshan’s dual-track urbanization from four perspectives: regional development, private business, government control, and major events. This study advanced our knowledge of the driving mechanisms of urban land expansion in small towns, from peri-urban areas to metropolitan sub-centers, and, thus, has important implications for Chinese urban planning and the management of metropolitan suburbs, especially those located in the Yangtze River Delta.
Keywords	case studies ; land ; land use ; markets ; raster data ; regression analysis ; river deltas ; sustainable development ; urbanization ; China ; Yangtze River
Language	English
Dates of publication	2022-0906
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2682955-1
ISSN	2073-445X
ISSN	2073-445X
DOI	10.3390/land11091495
Database	NAL-Catalogue (AGRICOLA)

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Article: Interaction of norfloxacin and hexavalent chromium with ferrihydrite nanoparticles: Synergistic adsorption and antagonistic aggregation behavior

Chen, Yufan / Li, Zhixiong

Chemosphere. 2022 July, v. 299

2022

Abstract	The co-existence of hexavalent chromium (Cr(VI)) and norfloxacin (NOR) can be detected in natural environments. However, the interaction of the co-existing Cr(VI), NOR and ferrihydrite nanoparticles (FNPs, a ubiquitous natural iron oxide nanoparticle) is lacking investigation. Figuring out this interaction could help us better predict the transport and fate of the relevant contaminants. Here, the adsorption and aggregation of FNPs in the presence of Cr(VI) and NOR were investigated. Comparing to FNPs interaction with Cr(VI) or NOR alone, the co-existence of Cr(VI) and NOR could lead to a synergistic effect to increase their adsorption onto FNPs. This observation can be attributed to the complexation between Cr(VI) and carboxyl or amino groups from NOR. Furthermore, the aggregation of FNPs could be accelerated by Cr(VI) through charge neutralization since the adsorption of Cr(VI) could decrease the surface potential of FNPs (positive charge). However, the presence of NOR will increase the surface charge, and thus stabilize FNPs. In general, the aggregation state of FNPs in the presence of co-existing Cr(VI) and NOR depends on their ratio. Overall, these understandings help us predict the transport and fate of FNPs and the associated contaminants in natural environments.
Keywords	adsorption ; aggregation behavior ; chromium ; ferrihydrite ; iron oxides ; neutralization ; norfloxacin ; synergism
Language	English
Dates of publication	2022-07
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2022.134386
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Article ; Online: Pioneering a chick embryo model to explore the intrauterine etiology of developmental dysplasia of the hip in oligohydramnios conditions.

Luo, Shaoting / Chen, Yufan / Zhou, Weizheng / Canavese, Federico / Li, Lianyong

Osteoarthritis and cartilage

2024

Abstract: Objective: To explore the impact of oligohydramnios on fetal movement and hip development, given its association with developmental dysplasia of the hip (DDH) but unclear mechanisms.: Methods: Chick embryos were divided into four groups based on the ... ...

Abstract	Objective: To explore the impact of oligohydramnios on fetal movement and hip development, given its association with developmental dysplasia of the hip (DDH) but unclear mechanisms. Methods: Chick embryos were divided into four groups based on the severity of oligohydramnios induced by amniotic fluid aspiration (control, 0.2 mL, 0.4 mL, 0.6 mL). Fetal movement was assessed by detection of movement and quantification of residual amniotic fluid volume. Hip joint development was assessed by gross anatomic analysis, micro-computed tomography (micro-CT) for cartilage assessment, and histologic observation at multiple time points. In addition, a subset of embryos from the 0.4 mL aspirated group underwent saline reinfusion and subsequent evaluation. Results: Increasing volumes of aspirated amniotic fluid resulted in worsening of fetal movement restrictions (e.g., 0.4 mL aspirated and control group at E10: frequency difference -7.765 [95% CI: -9.125, -6.404]; amplitude difference -0.343 [95% CI: -0.588, -0.097]). The 0.4 mL aspirated group had significantly smaller hip measurements compared to controls, with reduced acetabular length (-0.418 [95% CI: -0.575, -0.261]) and width (-0.304 [95% CI: -0.491, -0.117]) at day E14.5. Histological analysis revealed a smaller femoral head (1.084 ± 0.264 cm) and shallower acetabulum (0.380 ± 0.106 cm) in the 0.4 mL group. Micro-CT showed cartilage matrix degeneration (13.6% [95% CI: 0.6%, 26.7%], P = 0.043 on E14.5). Saline reinfusion resulted in significant improvements in the femoral head to greater trochanter (0.578 [95% CI: 0.323, 0.833], P = 0.001). Conclusions: Oligohydramnios can cause DDH by restricting fetal movement and disrupting hip morphogenesis in a time-dependent manner. Timely reversal of oligohydramnios during the fetal period may prevent DDH.
Language	English
Publishing date	2024-04-06
Publishing country	England
Document type	Journal Article
ZDB-ID	1167809-4
ISSN	1522-9653 ; 1063-4584
ISSN (online)	1522-9653
ISSN	1063-4584
DOI	10.1016/j.joca.2024.03.118
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Article ; Online: TriNymAuth: Triple Pseudonym Authentication Scheme for VANETs Based on Cuckoo Filter and Paillier Homomorphic Encryption.

Zhuang, Luyuan / Guo, Nan / Chen, Yufan

Sensors (Basel, Switzerland)

2023 Volume 23, Issue 3

Abstract: In VANETs, owing to the openness of wireless communication, it is necessary to change pseudonyms frequently to realize the unlinkability of vehicle identity. Moreover, identity authentication is needed, which is usually completed by digital certificates ... ...

Abstract	In VANETs, owing to the openness of wireless communication, it is necessary to change pseudonyms frequently to realize the unlinkability of vehicle identity. Moreover, identity authentication is needed, which is usually completed by digital certificates or a trusted third party. The storage and the communication overhead are high. This paper proposes a triple pseudonym authentication scheme for VANETs based on the Cuckoo Filter and Paillier homomorphic encryption (called TriNymAuth). TriNymAuth applies Paillier homomorphic encryption, a Cuckoo Filter combining filter-level and bucket-level, and a triple pseudonym (homomorphic pseudonym, local pseudonym, and virtual pseudonym) authentication to the vehicle identity authentication scheme. It reduces the dependence on a trusted third party and ensures the privacy and security of vehicle identity while improving authentication efficiency. Experimental results show that the insert overhead of the Cuckoo Filter is about 10 μs, and the query overhead reaches the ns level. Furthermore, TriNymAuth has significant cost advantages, with an OBU enrollment cost of only 0.884 ms. When the data rate in VANETs dr≤ 180 kbps, TriNymAuth has the smallest total transmission delay cost and is suitable for shopping malls and other places with dense traffic.
Language	English
Publishing date	2023-01-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s23031164
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Article: Editorial: Bacterial wilt: pathogenic mechanism, disease control, bacteria-plant and bacteria-environmental microorganism interactions.

Li, Peng / Zhang, Yong / Chen, Yufan

Frontiers in microbiology

2023 Volume 14, Page(s) 1322189

Language	English
Publishing date	2023-11-22
Publishing country	Switzerland
Document type	Editorial
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2023.1322189
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