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Article ; Online: Experimental evidence for immiscibility of enantiomeric polymers: Phase separation of high-molecular-weight poly(ʟ-lactide)/poly(ᴅ-lactide) blends and its impact on hindering stereocomplex crystallization.

Chen, Yujing / Lan, Qiaofeng

International journal of biological macromolecules

2024 Volume 260, Issue Pt 1, Page(s) 129459

Abstract: Although polymers tend not to mix, it remains challenging to characterize the immiscibility of enantiomeric poly(ʟ-lactide) (PLLA) and poly(ᴅ-lactide) (PDLA), particularly with equivalent and high molecular weight (high MW), which frustratingly disfavors ...

Abstract	Although polymers tend not to mix, it remains challenging to characterize the immiscibility of enantiomeric poly(ʟ-lactide) (PLLA) and poly(ᴅ-lactide) (PDLA), particularly with equivalent and high molecular weight (high MW), which frustratingly disfavors the exclusive stereocomplexation. By introducing a random copolymer (PLC) of ʟ-lactide and caprolactone to form binary blends with PLLA and PDLA, the phase behavior of high-MW PLLA/PDLA blends was investigated mainly by using differential scanning calorimetry (DSC) and atomic force microscopy (AFM). DSC results showed that PLLA/PLC blends exhibited a single glass transition temperature (T
MeSH term(s)	Polymers/chemistry ; Crystallization ; Molecular Weight ; Phase Separation ; Polyesters/chemistry ; Dioxanes
Chemical Substances	Polymers ; poly(lactide) (459TN2L5F5) ; dilactide (95-96-5) ; Polyesters ; Dioxanes
Language	English
Publishing date	2024-01-15
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2024.129459
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Article ; Online: Preparation and modification mechanism study of microwave-treated crumb rubber and waste engine oil-modified asphalt.

Chen, Yan / Hu, Kui / Chen, Yujing / Zhang, Taoli / Zhang, Wengang

Environmental science and pollution research international

2024 Volume 31, Issue 8, Page(s) 12483–12498

Abstract: The objective of this study was to characterize the performance of waste engine oil (WEO) and microwave-treated crumb rubber (CR)-modified asphalt (WEO-MCRA) and analyze the modification mechanism. The viscosity and dynamic shear rheological (DSR) tests ... ...

Abstract	The objective of this study was to characterize the performance of waste engine oil (WEO) and microwave-treated crumb rubber (CR)-modified asphalt (WEO-MCRA) and analyze the modification mechanism. The viscosity and dynamic shear rheological (DSR) tests were carried out to evaluate the viscoelasticity property of WEO-MCRA. The storage stability and fluorescence microscope (FM) tests were used to characterize the compatibility of the components. The Fourier transform infrared spectroscopy (FTIR) and molecular dynamic simulation were introduced to analyze the change of function groups and modification mechanism. The results demonstrated that introducing Wt.20% CR treated with microwave and Wt.6% WEO obtained a lower viscosity, excellent storage stability, and satisfactory elasticity properties of asphalt. The morphology of modifiers presented a thread-like structure microscopic with the range of WEO content Wt.3%-Wt.6%. Molecular dynamic simulations revealed that the aromatic may be intensively absorbed by CR and increase the likelihood of phase separation. WEO reduced the binding energy of CR to aromatic from 178.0 to 151.5 kcal/mol, which will contribute to the disaggregation of CR clusters. The diffusion coefficient shows a more obvious decrease with the addition of WEO and microwave treatment, which will benefit the stability of the asphalt. This study can provide a reference for the recycling of CR and WEO.
MeSH term(s)	Microwaves ; Rubber ; Elasticity ; Hydrocarbons
Chemical Substances	asphalt (8052-42-4) ; Rubber (9006-04-6) ; Hydrocarbons
Language	English
Publishing date	2024-01-17
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-023-31144-w
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Article ; Online: Neutrophil-to-lymphocyte ratio to estimate colorectal cancer liver metastasis: a commentary.

Wang, Kaina / Chen, Yujing / Nie, Zhonghua / Wang, Jingyu

International journal of surgery (London, England)

2023 Volume 109, Issue 9, Page(s) 2827–2828

MeSH term(s)	Humans ; Neutrophils ; Lymphocytes ; Lymphocyte Count ; Colorectal Neoplasms ; Liver Neoplasms ; Prognosis ; Retrospective Studies ; Kaplan-Meier Estimate
Language	English
Publishing date	2023-09-01
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	2212038-5
ISSN	1743-9159 ; 1743-9191
ISSN (online)	1743-9159
ISSN	1743-9191
DOI	10.1097/JS9.0000000000000535
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Article ; Online: Does the digital economy empower the green development of foreign trade?

Xu, Yingzhi / Chen, Yujing / Shi, Xiuyi

Environmental science and pollution research international

2023 Volume 30, Issue 51, Page(s) 110395–110416

Abstract: The digital economy has become a new driving force for China's economic development in recent years, and it may contribute to solving the corresponding problems of resource and environmental pressure. Therefore, this study strives to explore whether the ... ...

Abstract	The digital economy has become a new driving force for China's economic development in recent years, and it may contribute to solving the corresponding problems of resource and environmental pressure. Therefore, this study strives to explore whether the digital economy contributes to the green development of foreign trade. First, this study measures the digital economy development in China. Second, this study presents a list of environmental and polluting products and examines the impact of digital economy development on exports of representative products based on an extended gravity model. The main findings are as follows. First, the digital economy significantly promotes the green development of foreign trade. Second, the signing of Free Trade Agreements (FTAs) and the income level of importing countries and regions strengthen the role of the digital economy in promoting the green development of foreign trade. Third, the digital economy promotes the green development of foreign trade through green technological innovation. Finally, some policy implications are proposed based on the findings of this study.
MeSH term(s)	Sustainable Development ; Economic Development ; China ; Gravitation ; Policy
Language	English
Publishing date	2023-10-03
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-023-30076-9
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Article ; Online: Structure and function of the pyridoxal 5'-phosphate-dependent (PLP) threonine deaminase IlvA1 from Pseudomonas aeruginosa PAO1.

Jia, Haizhu / Chen, Yujing / Chen, Yuan / Liu, Ruihua / Zhang, Qionglin / Bartlam, Mark

Biochemical and biophysical research communications

2024 Volume 704, Page(s) 149710

Abstract: IlvA1, a pyridoxal phosphate-dependent (PLP) enzyme, catalyzes the deamination of l-threonine and l-serine to yield 2-ketobutyric acid or pyruvate. To gain insights into the function of IlvA1, we determined its crystal structure from Pseudomonas ... ...

Abstract	IlvA1, a pyridoxal phosphate-dependent (PLP) enzyme, catalyzes the deamination of l-threonine and l-serine to yield 2-ketobutyric acid or pyruvate. To gain insights into the function of IlvA1, we determined its crystal structure from Pseudomonas aeruginosa to 2.3 Å. Density for a 2-ketobutyric acid product was identified in the active site and a putative allosteric site. Activity and substrate binding assays confirmed that IlvA1 utilizes l-threonine, l-serine, and L-allo-threonine as substrates. The enzymatic activity is regulated by the end products l-isoleucine and l-valine. Additionally, the efficiency of d-cycloserine and l-cycloserine inhibitors on IlvA1 enzymatic activity was examined. Notably, site-directed mutagenesis confirmed the active site residues and revealed that Gln165 enhances the enzyme activity, emphasizing its role in substrate access. This work provides crucial insights into the structure and mechanism of IlvA1 and serves as a starting point for further functional and mechanistic studies of the threonine deaminase in P. aeruginosa.
MeSH term(s)	Butyrates ; Crystallography, X-Ray ; Cycloserine ; Phosphates ; Pseudomonas aeruginosa/genetics ; Pseudomonas aeruginosa/metabolism ; Pyridoxal Phosphate/metabolism ; Threonine/metabolism ; Threonine Dehydratase/genetics ; Threonine Dehydratase/metabolism
Chemical Substances	alpha-ketobutyric acid (600-18-0) ; Butyrates ; Cycloserine (95IK5KI84Z) ; Phosphates ; Pyridoxal Phosphate (5V5IOJ8338) ; Threonine (2ZD004190S) ; Threonine Dehydratase (EC 4.3.1.19)
Language	English
Publishing date	2024-02-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	205723-2
ISSN	1090-2104 ; 0006-291X ; 0006-291X
ISSN (online)	1090-2104 ; 0006-291X
ISSN	0006-291X
DOI	10.1016/j.bbrc.2024.149710
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Article: Adoption of Rehabilitation Climbing Wall Combined with Brain-computer Fusion Interface in Adolescent Idiopathic Scoliosis.

Kong, Dongmei / Chen, Yujing / Wang, Li / Lu, Yifang / Luo, Sudan / Chai, Hui / Chen, Lei

Alternative therapies in health and medicine

2024

Abstract: Background: As the adoption of brain-computer interface (BCI) technology in rehabilitation training is gradually maturing, the rehabilitation climbing walls combined with BCI technology are applied in adolescent idiopathic scoliosis (AIS) adoption ... ...

Abstract	Background: As the adoption of brain-computer interface (BCI) technology in rehabilitation training is gradually maturing, the rehabilitation climbing walls combined with BCI technology are applied in adolescent idiopathic scoliosis (AIS) adoption research. Methods: From January 2022 to January 2023, a total of 100 AIS patients were assigned into a control group (group C, rehabilitation climbing wall training) and an observation group (group B, rehabilitation climbing wall training based on BCI technology) equally and randomly. The therapeutic effects of the patients were analyzed, including the Cobb angle, waist range of motion, and quality of life. Results: The Cobb angles of all patients after three months of treatment were obviously smaller than those preoperatively, and the Cobb angle of patients in group B was smaller than that of group C. The improvement rate of the Cobb angle of patients in group B was substantially superior to that in group C (95%CI 17.8-42.6, P = .034). Moreover, patients in groups C and B had more extensive waist flexion, tension, and left ranges. Suitable lateral regions after three months of treatment than before and lower lumbar dysfunction scores, and group B was significantly better than group C (95%CI 20.3-35.4, P = .042). After three months of treatment, all patients' general condition, physical pain, physiological function, and mental health scores were higher than those preoperatively, and the scores in group B were substantially superior to those in group C (95%CI 51.3-84.2, P = .022). Furthermore, the total effective rate of patients in group B after three months was markedly superior to that in group C (96% vs. 82%) (95%CI 79.3-97.2, P = .014). Conclusion: The results of the study suggest that the rehabilitation climbing wall training method combined with brain-computer interface (BCI) technology has significant therapeutic effects on adolescent idiopathic scoliosis (AIS) patients. The intervention was found to effectively reduce the Cobb angle, increase the lumbar range of motion, improve lumbar function, and enhance the quality of life of the patients. These findings indicate that the adoption of rehabilitation climbing walls combined with BCI technology can be clinically valuable in the treatment of AIS. This approach holds promise in improving the rehabilitation outcomes for AIS patients, providing a non-invasive alternative to surgical interventions.
Language	English
Publishing date	2024-04-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	1225073-9
ISSN	1078-6791
ISSN	1078-6791
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Article ; Online: Staged treatment of Hunt-Hess IV distal posterior inferior cerebellar artery aneurysm: A case report.

Chen, Lang / Chen, Yu-Jing / Hu, Fei / Shao, Qiang

Asian journal of surgery

2023 Volume 46, Issue 9, Page(s) 4066–4067

MeSH term(s)	Humans ; Aneurysm ; Embolization, Therapeutic ; Arteries
Language	English
Publishing date	2023-04-26
Publishing country	Netherlands
Document type	Case Reports ; Letter
ZDB-ID	1068461-x
ISSN	0219-3108 ; 1015-9584
ISSN (online)	0219-3108
ISSN	1015-9584
DOI	10.1016/j.asjsur.2023.04.053
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Article ; Online: Study of the Microscopic Mechanism of Natural Rubber (Cis-1, 4-Polyisoprene, NR)/Polyethylene (PE) Modified Asphalt from the Perspective of Simulation.

Chen, Yujing / Hu, Kui / Yu, Caihua / Yuan, Dongdong / Ban, Xiaoyi

Polymers

2022 Volume 14, Issue 19

Abstract: This paper aims to study the interaction mechanism of waste tire/plastic modified asphalt from the microscopic perspective of molecules. Based on BIOVIA Materials Studio, a classic four-component asphalt model consisting of asphaltene ( ... ...

Abstract	This paper aims to study the interaction mechanism of waste tire/plastic modified asphalt from the microscopic perspective of molecules. Based on BIOVIA Materials Studio, a classic four-component asphalt model consisting of asphaltene (C
Language	English
Publishing date	2022-09-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527146-5
ISSN	2073-4360 ; 2073-4360
ISSN (online)	2073-4360
ISSN	2073-4360
DOI	10.3390/polym14194087
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Article ; Online: Effect of acupuncture on long-term outcomes in patients with post-stroke dysphagia.

Yao, Lulu / Liang, Wei / Du, Xin / Chen, Yujing / Huang, Xiaobo

NeuroRehabilitation

2022 Volume 51, Issue 3, Page(s) 433–441

Abstract: Background: Acupuncture has been used to treat patients with post-stroke neurological dysfunction.: Objective: The purpose of our observational study was to observe the long-term efficacy of acupuncture and investigate whether the acupuncture ... ...

Abstract	Background: Acupuncture has been used to treat patients with post-stroke neurological dysfunction. Objective: The purpose of our observational study was to observe the long-term efficacy of acupuncture and investigate whether the acupuncture treatment could short the recovery time of patients with post-stroke dysphagia. Methods: Medical records were reviewed to select patients who met the inclusion criteria for post-stroke dysphagia. Exposure factor was defined as received acupuncture during inpatient. Clinical data were obtained at the 6-month follow-up. The primary outcome was the time to improve the score of Food Intake Level Scale (FILS, 0-10) by 3 grades. Cox regression models were used to assess the relationship between acupuncture and recovery of dysphagia. Results: In acupuncture group, the median time to achieve clinical improvement of dysphagia was 97 days (95% CI, 93-124) compared with 119 days (95% CI, 108-145) in control group, with a statistically significant difference between the two groups (HR = 1.48; 95% CI 1.14-1.92; P = 0.003). At 6 months, 78 patients (60.5%) in acupuncture group reached excellent function and 61 patients (47.3%) in control group (RR = 1.28; 95% CI, 1.02-1.62; P = 0.045). 106 patients (82.2%) in acupuncture group achieved favorable function and 91 patients (70.5%) in control group (RR = 1.17; 95% CI, 1.02-1.35; P = 0.039). The outcome of adjusted multivariable Cox regression models showed that there was a difference in the recovery time of dysphagia between groups, HR = 1.79, 95% CI 1.34-2.39. The rates of adverse events were similar in both groups. Conclusions: Acupuncture can promote the recovery of post-stroke dysphagia, and has a better long-term efficacy. Besides, it can reduce the degree of disability and improve the quality of life.
MeSH term(s)	Humans ; Deglutition Disorders/etiology ; Deglutition Disorders/therapy ; Quality of Life ; Treatment Outcome ; Acupuncture Therapy ; Stroke/complications ; Stroke/therapy
Language	English
Publishing date	2022-07-21
Publishing country	Netherlands
Document type	Observational Study ; Journal Article
ZDB-ID	1087912-2
ISSN	1878-6448 ; 1053-8135
ISSN (online)	1878-6448
ISSN	1053-8135
DOI	10.3233/NRE-220113
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Article: The role of smoking and alcohol in mediating the effect of gastroesophageal reflux disease on lung cancer: A Mendelian randomization study.

Yang, Jing / Nie, Duorui / Chen, Yujing / Liu, Zixing / Li, Mengzhao / Gong, Chun / Liu, Qiong

Frontiers in genetics

2023 Volume 13, Page(s) 1054132

Abstract: Observational studies have suggested a positive association between gastroesophageal reflux disease and lung cancer, but due to the existence of confounders, it remains undetermined whether gastroesophageal reflux disease (GERD) has a causal association ... ...

Abstract	Observational studies have suggested a positive association between gastroesophageal reflux disease and lung cancer, but due to the existence of confounders, it remains undetermined whether gastroesophageal reflux disease (GERD) has a causal association with lung cancer. Therefore, Mendelian randomization (MR) analyses were applied to investigate the relationship between the two conditions. Two-sample Mendelian randomization analysis was utilized with summary genetic data from the European Bioinformatics Institute (602,604 individuals) and International Lung Cancer Consortium, which provides information on lung cancer and its histological subgroups. Furthermore, we used two-step Mendelian randomization and multivariable Mendelian randomization to estimate whether smoking initiation (311,629 cases and 321,173 controls) and alcohol intake frequency (
Language	English
Publishing date	2023-01-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606823-0
ISSN	1664-8021
ISSN	1664-8021
DOI	10.3389/fgene.2022.1054132
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