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Article ; Online: Self-Expression and Sharing around Chronic Illness on TikTok.

Zehrung, Rachael F / Chen, Yunan

AMIA ... Annual Symposium proceedings. AMIA Symposium

2024 Volume 2023, Page(s) 1334–1343

Abstract: While prior work has investigated the benefits of online health communities and general-purpose social media used for health-related purposes, little work examines the use of TikTok, an emerging social media platform with a substantial user base. The ... ...

Abstract	While prior work has investigated the benefits of online health communities and general-purpose social media used for health-related purposes, little work examines the use of TikTok, an emerging social media platform with a substantial user base. The platform's multimodal capabilities foster creative self-expression, while the content-driven network allows users to reach new audiences beyond their personal connections. To investigate users' challenges and motivations, we analyzed 160 TikTok videos that center on users' firsthand experiences living with chronic illness. We found that users struggled with a loss of normalcy and stigmatization in daily life. To contend with these challenges, they publicly shared their experiences to raise awareness, seek support from peers, and normalize chronic illness experiences. Based on our findings, we discuss the modalities of TikTok that facilitate self-expression around stigmatized topics and provide implications for the design of online health communities that better support adolescents and young adults.
MeSH term(s)	Adolescent ; Young Adult ; Humans ; Social Media ; Chronic Disease ; Motivation ; Peer Group
Language	English
Publishing date	2024-01-11
Publishing country	United States
Document type	Journal Article
ISSN	1942-597X
ISSN (online)	1942-597X
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Mobile Apps for Children's Health and Wellbeing: Design Features and Future Opportunities.

Lee, Jamie / Su, Zhaoyuan / Chen, Yunan

AMIA ... Annual Symposium proceedings. AMIA Symposium

2024 Volume 2023, Page(s) 1027–1036

Abstract: Mobile health apps hold great potential for promoting children's health and wellbeing. However, there is limited understanding of how these technologies are currently designed to support children with their health concerns or wellness goals. To gain ... ...

Abstract	Mobile health apps hold great potential for promoting children's health and wellbeing. However, there is limited understanding of how these technologies are currently designed to support children with their health concerns or wellness goals. To gain insight into the current landscape of mobile apps designed for children's health, we retrieved and reviewed 43 apps from IOS and Google Play store that are specifically marketed for children. Our qualitative analysis identified the dominant health focuses and goals of children's mobile health apps. We analyzed the primary users and their expectations as well as the methods of engagement and involvement adopted. Based on our findings, we discussed the opportunities to support children with chronic illnesses through mobile apps, design for dual use, and design for age appropriateness and digital health safety. This study provides insights and recommendations for app designers, health researchers, and policymakers on strategies for engaging children and parents while also promoting children's health and wellbeing through mobile technology.
MeSH term(s)	Child ; Humans ; Mobile Applications ; Child Health ; Telemedicine/methods ; Digital Health ; Parents
Language	English
Publishing date	2024-01-11
Publishing country	United States
Document type	Journal Article
ISSN	1942-597X
ISSN (online)	1942-597X
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Article ; Online: Perspectives on Privacy in the Post-Roe Era: A Mixed-Methods of Machine Learning and Qualitative Analyses of Tweets.

Guo, Yawen / Zehrung, Rachael / Genuario, Katie / Lu, Xuan / Mei, Qiaozhu / Chen, Yunan / Zheng, Kai

AMIA ... Annual Symposium proceedings. AMIA Symposium

2024 Volume 2023, Page(s) 951–960

Abstract: Abortion is a controversial topic that has long been debated in the US. With the recent Supreme Court decision to overturn Roe v. Wade, access to safe and legal reproductive care is once again in the national spotlight. A key issue central to this debate ...

Abstract	Abortion is a controversial topic that has long been debated in the US. With the recent Supreme Court decision to overturn Roe v. Wade, access to safe and legal reproductive care is once again in the national spotlight. A key issue central to this debate is patient privacy, as in the post-HITECH Act era it has become easier for medical records to be electronically accessed and shared. This study analyzed a large Twitter dataset from May to December 2022 to examine the public's reactions to Roe v. Wade's overruling and its implications for privacy. Using a mixed-methods approach consisting of computational and qualitative content analysis, we found a wide range of concerns voiced from the confidentiality of patient-physician information exchange to medical records being shared without patient consent. These findings may inform policy making and healthcare industry practices concerning medical privacy related to reproductive rights and women's health.
MeSH term(s)	Pregnancy ; Female ; Humans ; United States ; Privacy ; Abortion, Legal ; Supreme Court Decisions ; Confidentiality ; Machine Learning
Language	English
Publishing date	2024-01-11
Publishing country	United States
Document type	Journal Article
ISSN	1942-597X
ISSN (online)	1942-597X
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Article ; Online: Mechanistic insights and catalytic enhancement of phenolic wastewater supercritical water gasification: A combined experiment and density functional theory study.

Qi, Xingang / Zhang, Jiawei / Li, Xujun / Cui, Jinhua / Chen, Yunan / Jin, Hui / Guo, Liejin

Journal of environmental management

2024 Volume 358, Page(s) 120836

Abstract: Supercritical water gasification technology provides a favorable technology to achieve pollution elimination and resource utilization of phenolic wastewater. In this study, the reaction mechanism of phenolic wastewater supercritical water gasification ... ...

Abstract	Supercritical water gasification technology provides a favorable technology to achieve pollution elimination and resource utilization of phenolic wastewater. In this study, the reaction mechanism of phenolic wastewater supercritical water gasification was investigated using a combination of experimental and computational methods. Five reaction channels were identified to elucidate the underlying pathway of phenol decomposition. Importantly, the rate-determining step was found to be the dearomatization reaction. By integrating computational and experimental analyses, it was found that phenol decomposition via the path with the lowest energy barrier generates cyclopentadiene, featuring a dearomatization barrier of 70.97 kcal/mol. Additionally, supercritical water plays a catalytic role in the dearomatization process by facilitating proton transfer. Based on the obtained reaction pathway, alkali salts (Na
MeSH term(s)	Wastewater/chemistry ; Catalysis ; Phenols/chemistry ; Waste Disposal, Fluid/methods ; Water Pollutants, Chemical/chemistry ; Water/chemistry
Chemical Substances	Wastewater ; Phenols ; Water Pollutants, Chemical ; Water (059QF0KO0R)
Language	English
Publishing date	2024-04-09
Publishing country	England
Document type	Journal Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2024.120836
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Article ; Online: Sulfur migration mechanism of pig manure in supercritical water: A combined experimental and DFT study.

Zhang, Shuyuan / Du, Mingming / Ge, Hui / Rong, Siqi / Chen, Yunan / Guo, Liejin

Journal of hazardous materials

2024 Volume 471, Page(s) 134376

Abstract: Pig manure (PM) is a high concentration organic waste rich in sulfur, and its biofuel contains various sulfur-containing pollutants, which reduces the safety of the products. Supercritical water (SCW) can dissolve most organic matter, which is a ... ...

Abstract	Pig manure (PM) is a high concentration organic waste rich in sulfur, and its biofuel contains various sulfur-containing pollutants, which reduces the safety of the products. Supercritical water (SCW) can dissolve most organic matter, which is a technology worthy of further study. In order to reduce sulfur pollution in the process of PM resource utilization and better control the conversion path of sulfur, it is necessary to explore the migration mechanism of sulfur in the whole PM-SCW gasification process. The experimental results indicated that H
Language	English
Publishing date	2024-04-20
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1491302-1
ISSN	1873-3336 ; 0304-3894
ISSN (online)	1873-3336
ISSN	0304-3894
DOI	10.1016/j.jhazmat.2024.134376
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Article ; Online: Thermodynamic analysis of the series system for the supercritical water gasification of coal-water slurry

Guo, Shenghui / Wang, Yu / Shang, Fei / Yi, Lei / Chen, Yunan / Chen, Bin / Guo, Liejin

Energy. 2023 Nov., v. 283 p.128646-

2023

Abstract: Supercritical water gasification (SCWG) is a potential clean technology for utilizing solid fuel or waste without producing gaseous pollution. Efficient energy integration and recovery strategies play an essential role in the endothermal gasification ... ...

Abstract	Supercritical water gasification (SCWG) is a potential clean technology for utilizing solid fuel or waste without producing gaseous pollution. Efficient energy integration and recovery strategies play an essential role in the endothermal gasification process. Previous approaches have only focused on the heat source or heat transfer with very little attention to the utilization of the abundant supercritical water in the product gas. This paper proposes an innovative series design for heat integration in the SCWG system while taking the gasification process into account. Notably, the first-stage oxidized hot fluid containing abundant water is directly utilized as the gasification agent for the second-stage gasification reactor. The thermodynamic analysis shows that the cold gas and exergy efficiency in the two-stage series system is 17.4% and 15.0% higher than in the previous single-stage gasification reactor. The sensitivity analysis illustrates that increasing series stages and feedstock concentration while decreasing oxidation proportion and the agent-slurry ratio can improve the overall system efficiency by decreasing the demand for oxygen, power consumption, and heat transfer rate. The series design should offer an innovative and practical approach for the heat supply in the industrial SCWG plant.
Keywords	cold ; energy use and consumption ; exergy ; feedstocks ; fuels ; gasification ; heat transfer ; oxidation ; oxygen ; pollution ; slurries ; sustainable technology ; wastes ; Supercritical water gasification ; Series system ; Thermodynamic analysis ; Exergy efficiency ; Sensitivity analysis
Language	English
Dates of publication	2023-11
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	2019804-8
ISSN	0360-5442 ; 0360-5442
ISSN (online)	0360-5442
ISSN	0360-5442
DOI	10.1016/j.energy.2023.128646
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Article ; Online: Atypical histiocytoid cells in fine-needle aspiration cytology of metastatic papillary thyroid carcinoma: A potential diagnostic pitfall.

Chen, Yun-An / Lin, Shu-Jiuan / Teng, Hsin-Yu / Yang, Chi-Shun

Diagnostic cytopathology

2022 Volume 50, Issue 3, Page(s) 133–140

Abstract: Background: Fine needle aspiration (FNA) cytology of cervical lymph nodes is an effective diagnostic tool to detect metastatic papillary thyroid carcinoma (PTC) when typical cytomorphologic features of PTC are observed. However, the presence of atypical ...

Abstract	Background: Fine needle aspiration (FNA) cytology of cervical lymph nodes is an effective diagnostic tool to detect metastatic papillary thyroid carcinoma (PTC) when typical cytomorphologic features of PTC are observed. However, the presence of atypical histiocytoid cells (AHCs) due to cystic degeneration sometimes poses a diagnostic challenge. The purpose of this study was to evaluate the presence and cytomorphology of AHCs in metastatic PTC. Methods: We analyzed a total of 76 FNA cytological samples of cervical lymph nodes from 66 patients with metastatic PTC diagnosed during approximately 10-year period, from January 2010 to April 2020. Samples were either liquid based preparation (n = 53) or conventional smear (n = 23). Results: AHCs were present in 38 (50%) of the 76 FNA cases and the remaining 38 cases showed classic PTC features. Among the 38 cases, eight displayed pure AHCs that constituted 10.5% of all the metastatic PTC in the lymph nodes. Pure AHCs were more commonly detected in the liquid based preparation (7/53, 13.2%) than the conventional smear (1/23, 4.3%). The remaining 30 cases had AHCs mixed with the characteristic PTC components. The presence of AHCs was found to be statistically associated with cystic background (p < .002). Conclusion: Metastatic PTC frequently exhibits cystic degeneration and the FNA cytology may not yield classic cytological features of PTC. Pure AHCs composed 10.5% of all cases and might be a potential pitfall for liquid based preparation in diagnosing metastatic PTC. The finding of AHCs within the cystic background should raise the concern of metastatic PTC.
MeSH term(s)	Biopsy, Fine-Needle ; Carcinoma, Papillary/pathology ; Humans ; Lymphatic Metastasis ; Thyroid Cancer, Papillary ; Thyroid Neoplasms/diagnosis ; Thyroid Neoplasms/pathology
Language	English
Publishing date	2022-01-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	632710-2
ISSN	1097-0339 ; 8755-1039
ISSN (online)	1097-0339
ISSN	8755-1039
DOI	10.1002/dc.24932
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Article ; Online: Directional transformation and migration pathways of nitrogen during pig manure supercritical water gasification.

Du, Mingming / Xie, Anlan / Wei, Wenwen / Liu, Shi / Chen, Yunan / Guo, Liejin

Bioresource technology

2023 Volume 394, Page(s) 130256

Abstract: Nitrogen is a valuable nutrient element in pig manure. This work focuses on investigating the distribution, directional transformation, and migration pathways to facilitate the recovery of nitrogen from supercritical water gasification products. Results ... ...

Abstract	Nitrogen is a valuable nutrient element in pig manure. This work focuses on investigating the distribution, directional transformation, and migration pathways to facilitate the recovery of nitrogen from supercritical water gasification products. Results indicated that no nitrogen-containing gas was detected and 12.65 % of nitrogen remained in solid products. 82.49 % of nitrogen migrated into liquid products, which are predominated by ammonia. Catalysts were employed to promote the conversion of solid nitrogen to liquid nitrogen and organic nitrogen to ammonia. Finally, 85 % of nitrogen is enriched into liquid products and ammonia predominated the liquid nitrogen. The percentage of ammonia increased to 97.51 % at 620 °C in the presence of potassium carbonate. The migration pathways indicated that nitrogen was transformed into ammonia by various intermediates such as indole. The rest of the nitrogen remained in solid products with stable quaternary-nitrogen. These findings provide valuable insights into nitrogen management and recovery.
MeSH term(s)	Animals ; Swine ; Nitrogen/analysis ; Manure ; Ammonia ; Water ; Gases
Chemical Substances	Nitrogen (N762921K75) ; Manure ; Ammonia (7664-41-7) ; Water (059QF0KO0R) ; Gases
Language	English
Publishing date	2023-12-23
Publishing country	England
Document type	Journal Article
ZDB-ID	1065195-0
ISSN	1873-2976 ; 0960-8524
ISSN (online)	1873-2976
ISSN	0960-8524
DOI	10.1016/j.biortech.2023.130256
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Article ; Online: Olfactory bulb activity shapes the development of entorhinal-hippocampal coupling and associated cognitive abilities.

Chen, Yu-Nan / Kostka, Johanna K / Bitzenhofer, Sebastian H / Hanganu-Opatz, Ileana L

Current biology : CB

2023 Volume 33, Issue 20, Page(s) 4353–4366.e5

Abstract: The interplay between olfaction and higher cognitive processing has been documented in the adult brain; however, its development is poorly understood. In mice, shortly after birth, endogenous and stimulus-evoked activity in the olfactory bulb (OB) boosts ...

Abstract	The interplay between olfaction and higher cognitive processing has been documented in the adult brain; however, its development is poorly understood. In mice, shortly after birth, endogenous and stimulus-evoked activity in the olfactory bulb (OB) boosts the oscillatory entrainment of downstream lateral entorhinal cortex (LEC) and hippocampus (HP). However, it is unclear whether early OB activity has a long-lasting impact on entorhinal-hippocampal function and cognitive processing. Here, we chemogenetically silenced the synaptic outputs of mitral/tufted cells, the main projection neurons in the OB, during postnatal days 8-10. The transient manipulation leads to a long-lasting reduction of oscillatory coupling and weaker responsiveness to stimuli within developing entorhinal-hippocampal circuits accompanied by dendritic sparsification of LEC pyramidal neurons. Moreover, the transient silencing reduces the performance in behavioral tests involving entorhinal-hippocampal circuits later in life. Thus, neonatal OB activity is critical for the functional LEC-HP development and maturation of cognitive abilities.
MeSH term(s)	Mice ; Animals ; Olfactory Bulb/physiology ; Hippocampus/physiology ; Entorhinal Cortex/physiology ; Smell/physiology ; Cognition
Language	English
Publishing date	2023-09-19
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1071731-6
ISSN	1879-0445 ; 0960-9822
ISSN (online)	1879-0445
ISSN	0960-9822
DOI	10.1016/j.cub.2023.08.072
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Article ; Online: Thermodynamic and environmental assessment of black liquor supercritical water gasification integrated online salt recovery polygeneration system

Qi, Xingang / Chen, Yunan / Zhao, Jiuyun / Su, Di / Liu, Fan / Lu, Libo / Jin, Hui / Guo, Liejin

Energy. 2023 Sept., v. 278 p.127835-

2023

Abstract: Conventional black liquor treatment has weaknesses in pollution. Supercritical water gasification (SCWG) technology makes it possible to utilize the energy of black liquor cleanly. In this work, an auto-thermal SCWG black liquor polygeneration system ... ...

Abstract	Conventional black liquor treatment has weaknesses in pollution. Supercritical water gasification (SCWG) technology makes it possible to utilize the energy of black liquor cleanly. In this work, an auto-thermal SCWG black liquor polygeneration system integrated with online salt recovery was proposed. The performance of salt recovery and gasification was evaluated. The results show that the increasing gasification temperature, black liquor concentration, and salt discharge concentration are favorable to hydrogen production and system efficiency. For salt recovery, the sulfur-containing substances in black liquor are all converted into Na₂S/NaHS and recovered in this system. Through exergy analysis, the major exergy destructions are caused by the oxidation unit, SCWG unit, and sub-critical heat transfer. Then, the discharge brine heat is utilized to heat oxygen and feed to reduce the exergy destruction of reaction and heat transfer, which improved the energy efficiency from 78.03% to 88.16%, and the exergy efficiency from 60.86% to 64.10%. After adding a discharge salt utilization unit, the system's hydrogen production is 58,438 Nm³/h and the steam supply is 70,455 kW. This work provides theoretical guidance for the design and establishment of a black liquor SCWG industry system.
Keywords	energy efficiency ; environmental assessment ; exergy ; gasification ; heat transfer ; hydrogen production ; industry ; oxidation ; oxygen ; pollution ; steam ; temperature ; waste liquors ; Supercritical water ; Black liquor ; Salt recovery ; Exergy analysis
Language	English
Dates of publication	2023-09
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	2019804-8
ISSN	0360-5442 ; 0360-5442
ISSN (online)	0360-5442
ISSN	0360-5442
DOI	10.1016/j.energy.2023.127835
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