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  1. Article ; Online: Indoor Positioning Design for Mobile Phones via Integrating a Single Microphone Sensor and an

    Chen, Yung-Hsiang / Chang, Pei-Yu / Chen, Yung-Yue

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 3

    Abstract: An indoor positioning design developed for mobile phones by integrating a single microphone sensor, ... ...

    Abstract An indoor positioning design developed for mobile phones by integrating a single microphone sensor, an
    Language English
    Publishing date 2023-01-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23031508
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Acupoint Catgut Embedding Diminishes Fibromyalgia Pain through TRPV1 in the Mouse Brain.

    Lai, Po-Chih / Yen, Chia-Ming / Hsiao, I-Han / Chen, Yung-Hsiang / Lin, Yi-Wen

    Journal of integrative neuroscience

    2023  Volume 22, Issue 4, Page(s) 97

    Abstract: Background: Chronic pain refers to pain that persists for over three months. Chronic pain may restrict activities of daily living, including work, learning, social life, and can lead to anxiety, depression, and sleep disturbance. Imaging data have ... ...

    Abstract Background: Chronic pain refers to pain that persists for over three months. Chronic pain may restrict activities of daily living, including work, learning, social life, and can lead to anxiety, depression, and sleep disturbance. Imaging data have demonstrated that central sensitization often occurs in the brain of patients with chronic pain, which arises from imbalanced neurotransmission in the central nervous system. Transient receptor potential vanilloid 1 (TRPV1) is an ion channel to serve as an inflammatory detector in the brain. We aim to determine the properties of acupoint catgut embedding (ACE) on cold stress-induced mice fibromyalgia (FM) and surveyed the character of TRPV1 and linked molecules in chronic FM pain.
    Methods: Intermittent cold stress (ICS) was used to induce mice FM model. Mice were subgrouped into normal mice, ICS-induced FM group, FM mice with ACE, and FM in
    Results: Our behavioral experiments showed similar levels of pain response among all groups before treatment. After ICS, prolonged mechanical and thermal pain was initiated (mechanical threshold: 1.96 ± 0.12 g; thermal latency: 4.86 ± 0.21 s) and were alleviated by ACE treatment and
    Conclusions: These novel findings suggest that chronic FM pain can be modulated by ACE or
    MeSH term(s) Animals ; Mice ; Activities of Daily Living ; Acupuncture Points ; Brain/metabolism ; Catgut ; Chronic Pain ; Fibromyalgia/drug therapy ; Fibromyalgia/metabolism ; TRPV Cation Channels/genetics ; TRPV Cation Channels/metabolism
    Chemical Substances TRPV Cation Channels ; TRPV1 protein, mouse
    Language English
    Publishing date 2023-07-31
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2136427-8
    ISSN 0219-6352
    ISSN 0219-6352
    DOI 10.31083/j.jin2204097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Transforaminal Unilateral Biportal Endoscopic Spinal Surgery for Extraforaminal Lumbar Disc Herniation: A Retrospective Observational Study.

    Wu, Chih-Ying / Huang, Hsiang-Ming / Lee, Han-Chung / Tang, Chih-Hsin / Chen, Yung-Hsiang / Chiu, Cheng-Di

    World neurosurgery

    2024  Volume 183, Page(s) e658–e667

    Abstract: Objective: Biportal endoscopic spinal surgery (BESS) is recommended as a safer and less destructive option for lumbar disc herniations. However, limited data exist on clinical outcomes for extraforaminal lumbar disc herniation (ELDH) surgery. This ... ...

    Abstract Objective: Biportal endoscopic spinal surgery (BESS) is recommended as a safer and less destructive option for lumbar disc herniations. However, limited data exist on clinical outcomes for extraforaminal lumbar disc herniation (ELDH) surgery. This retrospective study presents our preliminary experience with transforaminal unilateral BESS for ELDH.
    Methods: Patients with lumbar radiculopathy refractory to conservative treatment, diagnosed with ELDH by magnetic resonance imaging, and treated with transforaminal unilateral BESS in 2021-2023 in 2 institutions in Taiwan were eligible for inclusion. Those with lumbar spondylolisthesis grade 2 or more with segmental instability, history of drug abuse or psychiatric diseases, or with a follow-up duration <1 year were excluded. Primary outcomes included visual analog scale for pain, assessed at 1 week, 1 month, 6 months, and 1 year using generalized estimating equations analysis; success and satisfaction of BESS graded by the Macnab criteria; and perioperative complications. Secondary outcomes were operative time and hospital length of stay.
    Results: Seventeen patients were included in the analysis, with a mean age of 65.8 years; 11 (64.7%) were males and 15 (88.2%) had no prior lumbar spine surgery. mean operative time was 107.9 minutes, and length of stay was 3.5 days. Graded by Macnab criteria, 16 (94.1%) of patients had good to excellent outcomes. Only 1 patient experienced complications. No recurrence/reoperation was observed. Generalized estimating equations analysis showed that postoperative visual analog scale scores decreased significantly at 1 week (adjusted Beta [aBeta] = -5.47, standard error: 0.29, P < 0.001), 1 month (aBeta = -5.82), 6 months (aBeta = -5.88), and 1 year (aBeta = -6.29).
    Conclusions: Transforaminal unilateral BESS is an alternative and feasible method for treating ELDH, producing good surgical outcomes with few complications and sustaining pain improvement. Future studies with larger patient numbers and comparisons between BESS and other minimally invasive techniques for ELDH are warranted.
    MeSH term(s) Male ; Humans ; Aged ; Female ; Intervertebral Disc Displacement/diagnostic imaging ; Intervertebral Disc Displacement/surgery ; Retrospective Studies ; Lumbar Vertebrae/diagnostic imaging ; Lumbar Vertebrae/surgery ; Diskectomy, Percutaneous/methods ; Endoscopy/methods ; Pain/surgery ; Treatment Outcome
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.12.162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Juan Bi Tang, a traditional Chinese medicine, for alleviating pain related to arteriovenous fistula in maintenance hemodialysis patients: An interventional pilot study with brief review.

    Hsu, Yung-Tang / Chen, Yung-Hsiang / Fu, Chung-Ming / Lee, Wen-Chin / Tsai, Ming-Yen

    Medicine

    2023  Volume 102, Issue 45, Page(s) e35974

    Abstract: Myofascial pain around an arteriovenous fistula (AVF) during hemodialysis (HD) can affect a patient compliance with HD and quality of life. Prolonged use of analgesics is often associated with increased adverse events. Juan Bi Tang (JBT) is an ancient ... ...

    Abstract Myofascial pain around an arteriovenous fistula (AVF) during hemodialysis (HD) can affect a patient compliance with HD and quality of life. Prolonged use of analgesics is often associated with increased adverse events. Juan Bi Tang (JBT) is an ancient decoction of Chinese traditional medicinal plants commonly used to treat spasms and pain in the shoulder and upper arm, and it is popularly believed to have favorable outcomes in Asian populations. This interventional prospective pilot study was worked to demonstrate the potential of JBT for fistula-associated myofascial pain in HD patients and to prepare for future randomized controlled trials. Eligible patients were enrolled in this study and took JBT to treat fistula-associated myofascial pain for 4 weeks. Pain scores on a visual analogue scale (VAS) were reported at baseline, after a 4-week intervention, and 2 weeks after completion of treatment. The Kidney Disease Quality of Life 36-Item Short Form and a safety laboratory monitor were statistically compared between different time points. A total of 20 patients were selected as eligible participants and completed the intervention and questionnaires. The mean VAS score was significantly reduced after JBT treatment (P < .01). Participants reported improved physical (P < .01) and mental health (P < .05) after treatment. However, only improvements in mental health were preserved 2 weeks after the end of treatment (P < .05). In this study, complementary JBT for HD patients with fistula-related myofascial pain was viable and well tolerated, and it demonstrated the expected effects on pain control.
    MeSH term(s) Humans ; Pilot Projects ; Medicine, Chinese Traditional ; Prospective Studies ; Quality of Life ; Pain ; Myofascial Pain Syndromes/therapy ; Renal Dialysis ; Arteriovenous Fistula
    Language English
    Publishing date 2023-11-02
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000035974
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Hemophagocytic syndrome in A patient of upper urinary tract urothelial cancer after Bacillus Calmette-Guérin instillation: A case report.

    Li, Ting-Lien / Huang, Chi-Ping / Lin, Chia-Yu / Ho, Mao-Wang / Cho, Chia-Hui / Chen, Yung-Hsiang / Chen, Wen-Chi

    Urology case reports

    2024  Volume 54, Page(s) 102730

    Abstract: Bacillus Calmette-Guérin (BCG) therapy is an adjuvant treatment for urothelial carcinomas of the upper urinary tract (UTUC). BCG therapy can result in various side effects. We present a case of a 67-year-old female with a history of UTUC who developed ... ...

    Abstract Bacillus Calmette-Guérin (BCG) therapy is an adjuvant treatment for urothelial carcinomas of the upper urinary tract (UTUC). BCG therapy can result in various side effects. We present a case of a 67-year-old female with a history of UTUC who developed disseminated tuberculosis following BCG instillation into the upper urinary tract after conservative management. This complex clinical scenario required a multidisciplinary approach, including antibiotic therapy, immunoglobulin infusion, and tailored tuberculosis treatment. The case underscores the importance of vigilance, early detection, and tailored interventions in managing disseminated tuberculosis arising from BCG therapy and rare complications like hemophagocytic syndrome.
    Language English
    Publishing date 2024-04-03
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2745459-9
    ISSN 2214-4420
    ISSN 2214-4420
    DOI 10.1016/j.eucr.2024.102730
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Rosmarinic acid Ameliorates neuronal regeneration in the bridging silicone rubber conduits of the sciatic nerve in taxol-treated rats.

    Chiu, Ping-Ling / Lin, Mei-Chen / Hsu, Shih-Tien / Ho, Tin-Yun / Chen, Yung-Hsiang / Chen, Chung-Chia / Chen, Yueh-Sheng

    Journal of traditional and complementary medicine

    2024  Volume 14, Issue 3, Page(s) 276–286

    Abstract: Background and aim: Taxol modulates local inflammatory conditions in peripheral nerves, which may impair their regeneration and recovery when injured. This study aimed to determine the effects of rosmarinic acid (RA, a polyphenol constituent of many ... ...

    Abstract Background and aim: Taxol modulates local inflammatory conditions in peripheral nerves, which may impair their regeneration and recovery when injured. This study aimed to determine the effects of rosmarinic acid (RA, a polyphenol constituent of many culinary herbs) on the regeneration of the sciatic nerves in the bridging conduits.
    Experimental procedure: In the cell study, RA decreased nuclear factor (NF)-κB activity induced by taxol in a dose dependency. In the animal model, taxol-treated rats were divided into 3 groups (n = 10/group): taxol (2 mg/kg body weight for 4 times) and taxol + RA (3 times/week for 4 weeks at 20 and 40 mg/kg body weight) groups. Macrophage infiltration, calcitonin gene-related peptide (CGRP) expression levels, neuronal connectivity, animal behavior, and neuronal electrophysiology were evaluated.
    Results and conclusion: At the end of 4 weeks, macrophage density, CGRP expression level, and axon number significantly increased in the RA group compared with the taxol group. The RA administration unaffected heat, cold plate licking latencies, and motor coordination. Moreover, the 40 mg/kg RA group had significantly larger nerve conduction velocity and less latency compared to the taxol group. This study suggested that RA could ameliorate local inflammatory conditions to augment the recovery of regenerating nerves by accelerating their regrowth and improving electrophysiological function in taxol-treated peripheral nerve injury repaired with the silicone rubber conduit.
    Language English
    Publishing date 2024-03-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2709698-1
    ISSN 2225-4110
    ISSN 2225-4110
    DOI 10.1016/j.jtcme.2024.03.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Drip-Tape-Following Approach Based on Machine Vision for a Two-Wheeled Robot Trailer in Strip Farming

    Chang, Chung-Liang / Chen, Hung-Wen / Chen, Yung-Hsiang / Yu, Chang-Chen

    Agriculture (Basel). 2022 Mar. 18, v. 12, no. 3

    2022  

    Abstract: Due to the complex environment in the field, using machine vision technology to enable the robot to travel autonomously was a challenging task. This study investigates a method based on mathematical morphology and Hough transformation for drip tape ... ...

    Abstract Due to the complex environment in the field, using machine vision technology to enable the robot to travel autonomously was a challenging task. This study investigates a method based on mathematical morphology and Hough transformation for drip tape following by a two-wheeled robot trailer. First, an image processing technique was utilized to extract the drip tape in the image, including the selection of the region of interest (ROI), Red-Green-Blue (RGB) to Hue-Saturation-Value (HSV) color space conversion, color channel selection, Otsu’s binarization, and morphological operations. The line segments were obtained from the extracted drip tapes image by a Hough line transform operation. Next, the deviation angle between the line segment and the vertical line in the center of the image was estimated through the two-dimensional law of cosines. The steering control system could adjust the rotation speed of the left and right wheels of the robot to reduce the deviation angle, so that the robot could stably travel along the drip tape, including turning. The guiding performance was evaluated on the test path formed by a drip tape in the field. The experimental results show that the proposed method could achieve an average line detection rate of 97.3% and an average lateral error of 2.6 ± 1.1 cm, which was superior to other drip-tape-following methods combined with edge detection, such as Canny and Laplacian.
    Keywords agriculture ; color ; computer vision
    Language English
    Dates of publication 2022-0318
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2651678-0
    ISSN 2077-0472
    ISSN 2077-0472
    DOI 10.3390/agriculture12030428
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Pain Experiences and Coping Strategies in Rural Older Adults With Chronic Musculoskeletal Pain in Mountainous Areas of Taiwan.

    Liu, Chun-Ting / Wu, Bei-Yu / Chen, Yung-Hsiang / Tsai, Ming-Yen

    Pain management nursing : official journal of the American Society of Pain Management Nurses

    2021  Volume 23, Issue 4, Page(s) 524–531

    Abstract: Background: Although rural communities are home to a higher proportion of older residents, they provide fewer healthcare services than do urban core communities. Chronic musculoskeletal (MSK) pain is often associated with reduced daily activity and ... ...

    Abstract Background: Although rural communities are home to a higher proportion of older residents, they provide fewer healthcare services than do urban core communities. Chronic musculoskeletal (MSK) pain is often associated with reduced daily activity and quality of life in older adults, particularly those in rural areas.
    Aims: This study investigated the pain experiences and coping strategies in rural older adults with MSK pain in Taiwan.
    Methods: A structured questionnaire was used to collect data from rural older adults with chronic MSK pain in mountainous areas of Taiwan.
    Results: In total, 55 rural older adults were enrolled in this study. The most common pain sites were the low back and knees. The main cause of pain was osteoarthritis. Three quarters of the participants suffered from moderate to severe chronic MSK pain on average. The results revealed that behavioral strategies were used more often than cognitive strategies. Regarding behavioral strategies, the most common non-pharmacologic and pharmacologic pain coping strategies were to rest and to take Chinese medicine, respectively. The most common cognitive strategy for pain coping was to talk to others.
    Conclusions: The findings suggested that pain management for chronic MSK pain in rural older adults was inadequate in mountainous areas of Taiwan. Most rural older adults used multiple coping strategies to deal with their pain, and behavioral strategies were favored over cognitive strategies.
    MeSH term(s) Adaptation, Psychological ; Aged ; Chronic Pain ; Humans ; Musculoskeletal Pain ; Quality of Life ; Rural Population ; Taiwan
    Language English
    Publishing date 2021-09-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2213260-0
    ISSN 1532-8635 ; 1524-9042
    ISSN (online) 1532-8635
    ISSN 1524-9042
    DOI 10.1016/j.pmn.2021.08.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Comparative Outcomes of Robotic Radical Prostatectomy in Patients with Locally Advanced Prostate Cancer.

    Li, Po-I / Chen, Szu-Ju / Chen, Yung-Hsiang / Chen, Wen-Chi / Huang, Chi-Ping

    Medicina (Kaunas, Lithuania)

    2022  Volume 58, Issue 12

    Abstract: The effectiveness of radical prostatectomy alone for locally advanced prostate cancer is controversial owing to an increased complication rate and treatment-related morbidity. With technical advances and refinements in surgical techniques, robotic- ... ...

    Abstract The effectiveness of radical prostatectomy alone for locally advanced prostate cancer is controversial owing to an increased complication rate and treatment-related morbidity. With technical advances and refinements in surgical techniques, robotic-assisted radical prostatectomy (RARP) has improved the outcomes of patients with locally advanced prostate cancer. RARP therefore plays a role in the treatment of locally advanced prostate cancer. In this study, we enrolled a total of 76 patients with pathologic stage pT3a, pT3b, pT4, or pN1. All patients were followed from surgery to June 2022, and their characteristics, perioperative outcomes, complications, adjuvant therapies and outcomes were analyzed. The median age of the patients was 69 years, and the initial PSA level was 20.5 (IQR 10.8-31.6) ng/mL. The median operative time was 205 (IQR 182-241) minutes. Sixty-six patients (86.8%) regained continence within 1 year, and the continence rate within 3 years of follow-up was 90.8% (69 patients). The overall survival rate was 100%. Twenty-two patients had BCR, of whom 13 received salvage androgen deprivation therapy (ADT), 2 received salvage external beam radiation therapy (EBRT) alone, and 7 received combined ADT and EBRT. No patient had disease progression to castration-resistant prostate cancer during a median 36 months of follow-up after salvage therapy. Our results suggest that RARP can also decrease tumor burden and allow for accurate and precise pathological staging with the need for subsequent treatment. Therefore, we recommend that RARP represents a well-standardized, safe, and oncologically effective option for patients with locally advanced prostate cancer.
    Language English
    Publishing date 2022-12-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina58121820
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Percutaneous Nephrolithotomy Combined Antegrade Flexible Ureteroscope for Complete Staghorn Stones: A Case Report of a New Concept of Stone Surgery.

    Pan, Szu-Ying / Huang, Chi-Ping / Chen, Wen-Chi / Chen, Yung-Hsiang / Chou, Eric Chieh-Lung

    Medicina (Kaunas, Lithuania)

    2022  Volume 59, Issue 1

    Abstract: Percutaneous nephrolithotomy (PCNL) is the treatment of choice for staghorn stones. However, residual stones in calyces remain a challenge due to the limited angle which makes the approach difficult. The new operative technique of endoscopic combined ... ...

    Abstract Percutaneous nephrolithotomy (PCNL) is the treatment of choice for staghorn stones. However, residual stones in calyces remain a challenge due to the limited angle which makes the approach difficult. The new operative technique of endoscopic combined intrarenal surgery (ECIRS), which integrates the advantages of PCNL and retrograde intrarenal surgery (RIRS), was developed to overcome this difficulty. However, two experienced urologists are required to perform ECIRS, and the patient has to be placed in the Galdakao-modified supine Valdivia position or modified prone split-leg position which cannot be achieved in the elderly or patients with ankylosing arthritis, as it may cause harm due to abnormal traction of the joints. In addition, it is difficult for surgeons to create an ideal access tract to perform PCNL in this position. We report the case of a 72-year-old female patient with left staghorn stone. We performed RIRS first and then placed the patient in the decubitus position for PCNL with antegrade flexible ureteroscopy. This method allows patients to be placed in an easier position, with the use of flexible ureteroscopy through a nephroscope to find previously unreachable stones. Moreover, in addition to the more comfortable position both for surgeons and patients, this procedure can also deal with large complex renal stones as with ECIRS. We also created a brand-new definition for stone clearance rate, namely, stone reduction efficiency (SRE). There was a high stone reduction efficiency of 12.64 (mm
    MeSH term(s) Female ; Humans ; Aged ; Nephrolithotomy, Percutaneous ; Ureteroscopes ; Nephrostomy, Percutaneous/adverse effects ; Nephrostomy, Percutaneous/methods ; Kidney Calculi/surgery ; Ureteroscopy/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2022-12-23
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59010035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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