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Article ; Online: The neuromuscular control for lower limb exoskeleton- a 50-year perspective.

Chen, Yu-Ning / Wu, Yi-Ning / Yang, Bing-Shiang

2023 Volume 158, Page(s) 111738

Abstract: Historically, impaired lower limb function has resulted in heavy health burden and large economic loss in society. Although experts from various fields have put large amounts of effort into overcoming this challenge, there is still not a single standard ... ...

Abstract	Historically, impaired lower limb function has resulted in heavy health burden and large economic loss in society. Although experts from various fields have put large amounts of effort into overcoming this challenge, there is still not a single standard treatment that can completely restore the lost limb function. During the past half century, with the advancing understanding of human biomechanics and engineering technologies, exoskeletons have achieved certain degrees of success in assisting and rehabilitating patients with loss of limb function, and therefore has been spotlighted in both the medical and engineering fields. In this article, we review the development milestones of lower limb exoskeletons as well as the neuromuscular interactions between the device and wearer throughout the past 50 years. Fifty years ago, the lower-limb exoskeletons just started to be devised. We review several prototypes and present their designs in terms of structure, sensor and control systems. Subsequently, we introduce the development milestones of modern lower limb exoskeletons and discuss the pros and cons of these differentiated devices. In addition, we summarize current important neuromuscular control systems and sensors; and discuss current evidence demonstrating how the exoskeletons may affect neuromuscular control of wearers. In conclusion, based on our review, we point out the possible future direction of combining multiple current technologies to build lower limb exoskeletons that can serve multiple aims.
MeSH term(s)	Humans ; Exoskeleton Device ; Lower Extremity ; Biomechanical Phenomena
Language	English
Publishing date	2023-07-22
Publishing country	United States
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	218076-5
ISSN	1873-2380 ; 0021-9290
ISSN (online)	1873-2380
ISSN	0021-9290
DOI	10.1016/j.jbiomech.2023.111738
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Article ; Online: Silver nanoparticles doped TiO

Chen, Yuning / Feng, Li

Journal of photochemistry and photobiology. B, Biology

2020 Volume 205, Page(s) 111807

Abstract: The formation of the carbon‑carbon bond in the synthetic chemistry explored in many ways. Suzuki-cross coupling is one of the ways to make bonds between two carbon atoms of similar molecules or different molecules. CC bond was successfully formed between ...

Abstract	The formation of the carbon‑carbon bond in the synthetic chemistry explored in many ways. Suzuki-cross coupling is one of the ways to make bonds between two carbon atoms of similar molecules or different molecules. CC bond was successfully formed between two aryl rings of aryl halides and phenylboronic acid at room temperature and atmospheric pressure under the visible illuminance. In this work we report, an in-situ synthesis of silver nanoparticles doped TiO
MeSH term(s)	Boronic Acids/chemistry ; Catalysis ; Hydrocarbons, Brominated/chemistry ; Light ; Metal Nanoparticles/chemistry ; Metal Nanoparticles/radiation effects ; Silver/chemistry ; Silver/radiation effects ; Titanium/chemistry ; Titanium/radiation effects
Chemical Substances	Boronic Acids ; Hydrocarbons, Brominated ; titanium dioxide (15FIX9V2JP) ; Silver (3M4G523W1G) ; Titanium (D1JT611TNE) ; benzeneboronic acid (L12H7B02G5)
Language	English
Publishing date	2020-01-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	623022-2
ISSN	1873-2682 ; 1011-1344
ISSN (online)	1873-2682
ISSN	1011-1344
DOI	10.1016/j.jphotobiol.2020.111807
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Article: Silver nanoparticles doped TiO2 catalyzed Suzuki-coupling of bromoaryl with phenylboronic acid under visible light

Chen, Yuning / Feng, Li

Journal of photochemistry and photobiology. 2020 Apr., v. 205

2020

Abstract: The formation of the carbon‐carbon bond in the synthetic chemistry explored in many ways. Suzuki-cross coupling is one of the ways to make bonds between two carbon atoms of similar molecules or different molecules. CC bond was successfully formed between ...

Abstract	The formation of the carbon‐carbon bond in the synthetic chemistry explored in many ways. Suzuki-cross coupling is one of the ways to make bonds between two carbon atoms of similar molecules or different molecules. CC bond was successfully formed between two aryl rings of aryl halides and phenylboronic acid at room temperature and atmospheric pressure under the visible illuminance. In this work we report, an in-situ synthesis of silver nanoparticles doped TiO2 nanoparticles (NPs) and studied its catalytic activity as an eco-friendly, simple, recyclable and efficient catalyst for one-pot Suzuki-coupling of bromoaryl with phenylboronic acid under visible light. Only, 45 mg of the catalyst resulted in a 98% conversion of p-ethyl bromobenzene with a 97% yield of p-ethyl biphenyl using toluene as the solvent in the presence of visible light at atmospheric pressure. The electron-donating groups (e.g., ethyl group) substituted bromobenzene resulted in the maximum yields than that of the substitution with the electron-withdrawing groups. The catalyst shown significant catalytic activity up to seven recycling runs without any loss. The doping of silver nanoparticles boosted the catalytic activity at titanium dioxide surface as well as inside the pores. The high surface area of the semiconductor support provides the sites for accommodated silver nanoparticles and shows enhanced reactivity towards the coupling reaction of bromoaryl with phenylboronic acid. The as-synthesized catalyst was thoroughly characterized by XRD, TEM, EDX, XPS, FTIR, TGA, UV–vis, Raman and BET analysis. The high recyclability of the photocatalyst remarked the footprints in the CC coupling reactions.
Keywords	Fourier transform infrared spectroscopy ; Raman spectroscopy ; Suzuki reaction ; X-ray diffraction ; X-ray photoelectron spectroscopy ; ambient temperature ; atmospheric pressure ; biphenyl ; bromobenzenes ; carbon ; catalytic activity ; chemical bonding ; energy-dispersive X-ray analysis ; light ; moieties ; nanoparticles ; nanosilver ; organic halogen compounds ; phenylboronic acids ; photocatalysts ; semiconductors ; solvents ; surface area ; thermogravimetry ; titanium dioxide ; toluene ; transmission electron microscopy ; ultraviolet-visible spectroscopy
Language	English
Dates of publication	2020-04
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	623022-2
ISSN	1873-2682 ; 1011-1344
ISSN (online)	1873-2682
ISSN	1011-1344
DOI	10.1016/j.jphotobiol.2020.111807
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Application of new chitosan 2,4-dihydroxyacetophenone Schiff base @SrFe

Wei, Wei / Wu, Houfan / Chen, Yuning / Zhong, Kunyu / Feng, Li

International journal of biological macromolecules

2022 Volume 226, Page(s) 336–344

Abstract: A new chitosan 2,4-dihydroxyacetophenone Schiff base @ ... ...

Abstract	A new chitosan 2,4-dihydroxyacetophenone Schiff base @SrFe
Language	English
Publishing date	2022-12-08
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2022.12.041
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Article ; Online: Graft-versus-Host Disease Modulation by Innate T Cells.

Fang, Ying / Zhu, Yichen / Kramer, Adam / Chen, Yuning / Li, Yan-Ruide / Yang, Lili

International journal of molecular sciences

2023 Volume 24, Issue 4

Abstract: Allogeneic cell therapies, defined by genetically mismatched transplantation, have the potential to become a cost-effective solution for cell-based cancer immunotherapy. However, this type of therapy is often accompanied by the development of graft- ... ...

Abstract	Allogeneic cell therapies, defined by genetically mismatched transplantation, have the potential to become a cost-effective solution for cell-based cancer immunotherapy. However, this type of therapy is often accompanied by the development of graft-versus-host disease (GvHD), induced by the mismatched major histocompatibility complex (MHC) between healthy donors and recipients, leading to severe complications and death. To address this issue and increase the potential for allogeneic cell therapies in clinical practice, minimizing GvHD is a crucial challenge. Innate T cells, encompassing subsets of T lymphocytes including mucosal-associated invariant T (MAIT) cells, invariant natural killer T (iNKT) cells, and gamma delta T (γδ T) cells, offer a promising solution. These cells express MHC-independent T-cell receptors (TCRs), allowing them to avoid MHC recognition and thus GvHD. This review examines the biology of these three innate T-cell populations, evaluates research on their roles in GvHD modulation and allogeneic stem cell transplantation (allo HSCT), and explores the potential futures for these therapies.
MeSH term(s)	Humans ; Hematopoietic Stem Cell Transplantation/adverse effects ; Graft vs Host Disease/etiology ; Mucosal-Associated Invariant T Cells ; Natural Killer T-Cells ; Immunotherapy/adverse effects
Language	English
Publishing date	2023-02-17
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms24044084
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Article: Contemporary Management of Pediatric Brainstem Tumors.

Chou, Sheng-Che / Chen, Yu-Ning / Huang, Hsin-Yi / Kuo, Meng-Fai / Wong, Tai-Tong / Kuo, Sung-Hsin / Yang, Shih-Hung

Advances and technical standards in neurosurgery

2024 Volume 49, Page(s) 231–254

Abstract: Brain tumors are the second most common malignancy in childhood. Around 15-20% of pediatric brain tumors occur in the brainstem. The most common type of brainstem tumor are diffuse tumors in the ventral pons, whereas focal tumors tend to arise from the ... ...

Abstract	Brain tumors are the second most common malignancy in childhood. Around 15-20% of pediatric brain tumors occur in the brainstem. The most common type of brainstem tumor are diffuse tumors in the ventral pons, whereas focal tumors tend to arise from the midbrain, medulla, and dorsal pons. Glioma is the most common pathological entity. Contemporary management consists of surgery, radiotherapy, chemotherapy, and other adjuvant treatment. Surgical options range from biopsy to radical excision. Biopsy can be performed for diagnostic and prognostic purposes, or in the setting of clinical trials, mainly for diffuse intrinsic pontine gliomas. For focal tumors, surgeons need to carefully balance clinical outcomes against possible neurological sequelae in order to achieve maximal safe resection. Radiotherapy is essential for control of high-grade tumors and may be applied to residual or recurrent low-grade tumors. Proton therapy may provide similar efficacy and less neurotoxicity in comparison to conventional photon therapy. Oncological treatment continues to evolve from conventional chemotherapy to targeted therapy, immunotherapy, and other novel treatment methods and holds great potential as adjuvant therapy for pediatric brainstem tumors.
MeSH term(s)	Humans ; Brain Stem Neoplasms/therapy ; Brain Stem Neoplasms/pathology ; Child ; Glioma/therapy ; Glioma/pathology ; Neurosurgical Procedures/methods ; Combined Modality Therapy
Language	English
Publishing date	2024-05-03
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	189820-6
ISSN	0095-4829
ISSN	0095-4829
DOI	10.1007/978-3-031-42398-7_11
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Article: The effect of counter-ion substitution on poly(phthalazinone ether ketone) amphoteric ion exchange membranes for vanadium redox flow battery

Chen, Yuning / Zhang, Shouhai / Liu, Qian / Jian, Xigao

Journal of membrane science. 2021 Feb. 15, v. 620

2021

Abstract: The study proposed a novel method to prepare poly(phthalazinone ether ketone) amphoteric ion exchange membranes (Q/S-M) with both increased efficiency and chemical stability for vanadium redox flow battery (VRB) applications. Q/S-M membranes were ... ...

Abstract	The study proposed a novel method to prepare poly(phthalazinone ether ketone) amphoteric ion exchange membranes (Q/S-M) with both increased efficiency and chemical stability for vanadium redox flow battery (VRB) applications. Q/S-M membranes were obtained after the successive amination and acidification process of blend base membranes prepared from brominated poly(phthalazinone ether ketone) (BPPEK) and sulfonated poly(phthalazinone ether ketone) substituted by counter-ions (SPPEK-M), where M was defined as counter-ions: Li⁺, Na⁺ and K⁺. The study analyzed the effect of counter-ion size on properties of Q/S-M membranes, which were compared with those for Q/S membrane obtained from BPPEK and SPPEK in acid form. Q/S and Q/S-M membranes maintained the same composition of ionic groups. The Q/S-M membranes induced by bigger counter-ion size showed the increasing of water content and ion diffusion rate, which was higher than that of Q/S membrane. Related to Q/S membrane, Q/S–K membrane possessed almost half area resistance (0.67 Ω cm² vs 1.43 Ω cm²), and the value was close to that of Nafion115. Q/S-M membranes exhibited a 96.0–98.8% decrease in VO²⁺ permeability over Nafion115. Q/S–K membrane displayed a 6.5% increase in VE and correspondingly a 6.2% increase in EE over Q/S membrane, maintaining superior EE than Nafion115 (89.7% vs 86.5%). The ex-situ degradation test in VO₂⁺ solutions indicated that despite close EE, Q/S–K membrane showed superior chemical stability over amphoteric ion exchange membranes (AIEMs) in our previous works. There was no obvious efficiency decay of Q/S–K membrane during 100-cycles test, indicating the good duration in operating VRB.
Keywords	acidification ; amination ; batteries ; bromination ; ion exchange ; permeability ; vanadium ; water content
Language	English
Dates of publication	2021-0215
Publishing place	Elsevier B.V.
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	194516-6
ISSN	0376-7388
ISSN	0376-7388
DOI	10.1016/j.memsci.2020.118816
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Structuring alginate/dopamine powder into macroscopic aerogel microsphere for exceptional removal of tetracycline from water: Performance and mechanisms

Chen, Bo / Yu, Fengling / Wang, Sha / Liu, Yang / Li, Dehong / Chen, Yuning / Dao, Guohua / Xu, Zhixiang / Pan, Xuejun

International Journal of Biological Macromolecules. 2023 July, v. 242 p.124994-

2023

Abstract: Aerogel was selected as one of IUPAC Top Ten Emerging Technologies in Chemistry in 2022, and has attracted tremendous concerns of scientists in removal of emerging contaminants. In this work a novel Fe³⁺ cross-linked alginate aerogel (SA/DA-Fe³⁺) with ... ...

Abstract	Aerogel was selected as one of IUPAC Top Ten Emerging Technologies in Chemistry in 2022, and has attracted tremendous concerns of scientists in removal of emerging contaminants. In this work a novel Fe³⁺ cross-linked alginate aerogel (SA/DA-Fe³⁺) with multiple sorption sites were facilely fabricated and applied for highly efficient removal of tetracycline (TC) from water. Results showed that Fe³⁺ and DA cooperatively improve adsorption of TC and TC was efficiently removed over a broad pH range of 4–8. The kinetics process can be better described by a chemisorption controlled pseudo-second-order kinetics model and Langmuir isotherm equation with characteristics of monolayer coverage. The fitted qₘₐₓ value of TC at ambient temperature was 804.6 mg g⁻¹ higher than those of other reported adsorbents. Multiple interactions including π-π EDA, complexation, hydrogen bonding, electrostatic attraction, etc. were involved in adsorption process. Moreover, SA/DA-Fe³⁺ aerogel exhibited satisfactory stability, reusability, and recyclability for consecutive applications. Most importantly, after consecutively running for >1000 h with dynamic sorption capacity over 500 mg g⁻¹, the packed-column was still not saturated, manifesting its great potentials for treating actual wastewaters. Thus, above superiorities make SA/DA-Fe³⁺ a promising candidate adsorbent for treating TC-containing wastewater.
Keywords	adsorbents ; adsorption ; aerogels ; alginates ; ambient temperature ; crosslinking ; dopamine ; electrostatic interactions ; equations ; hydrogen ; microparticles ; models ; pH ; sorption isotherms ; tetracycline ; wastewater ; Fe3+-crosslinked alginate aerogel ; Dopamine incorporation ; Tetracycline adsorption
Language	English
Dates of publication	2023-07
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2023.124994
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Book ; Online: Satellite downlink scheduling under breakpoint resume mode

Chang, Zhongxiang / Chen, Yuning / Zhou, Zhongbao

2022

Abstract: A novel problem called satellite downlink scheduling problem (SDSP) under breakpoint resume mode (SDSP-BRM) is studied in our paper. Compared to the traditional SDSP where an imaging data has to be completely downloaded at one time, SDSP-BRM allows the ... ...

Abstract	A novel problem called satellite downlink scheduling problem (SDSP) under breakpoint resume mode (SDSP-BRM) is studied in our paper. Compared to the traditional SDSP where an imaging data has to be completely downloaded at one time, SDSP-BRM allows the data of an imaging data be broken into a number of pieces which can be downloaded in different playback windows. By analyzing the characteristics of SDSP-BRM, we first propose a mixed integer programming model for its formulation and then prove the NP-hardness of SDSP-BRM. To solve the problem, we design a simple and effective heuristic algorithm (SEHA) where a number of problem-tailored move operators are proposed for local searching. Numerical results on a set of well-designed scenarios demonstrate the efficiency of the proposed algorithm in comparison to the general purpose CPLEX solver. We conduct additional experiments to shed light on the impact of the segmental strategy on the overall performance of the proposed SEHA.
Keywords	Computer Science - Artificial Intelligence
Subject code	006
Publishing date	2022-07-04
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: A parametric study on the efficiency of a solar evacuated tube collector using phase change materials: A transient simulation

Feng, Li / Liu, Jiajun / Lu, Haitao / Chen, Yuning / Wu, Shenyu

Renewable energy. 2022 Nov., v. 199

2022

Abstract: Evacuated solar collectors are renewable systems that provide a considerable quantity of heat during test time. However, this system is unable to provide energy in the absence of sunlight. Thus, this study attempted to numerically study a Solar Evacuated ...

Abstract	Evacuated solar collectors are renewable systems that provide a considerable quantity of heat during test time. However, this system is unable to provide energy in the absence of sunlight. Thus, this study attempted to numerically study a Solar Evacuated Tube Collector (ETC) performance using phase change materials (PCM). PCM can store considerable thermal energy during the day and release it to the system at night. In order to simulate the ETC-PCM system, an accurate three-dimensional model considering all the layers is designed. In the present numerical investigation, the effect of various properties of the PCM, including enthalpy, melting point, and thermal conductivity, on the outputs of the ETC-PCM system are evaluated separately. Also, the effects of some other factors, such as MWCNT nanoparticles dispersion in the base fluid and working fluid mass flow rate, on the performance of the ETC-PCM system are studied. Furthermore, to evaluate the performance of the system and model the behavior of the PCM during the day, the system is simulated under the weather condition of Hing Kong from sunrise until sunset. According to the results of the simulations, a reduction in PCM melting point from 50 °C to 35 °C can elevate the efficiency of the ETC-PCM device. PCM with a high melting point remains solid during the day. Thus, its effect on the output of the system cannot be revealed. Moreover, it is found that the system using PCM with the latent heat of 160 kJ/kg has the best performance among the studied cases. Besides, it is illustrated that raising the mass flow rate of working fluid and mass fraction of nanoparticles can enhance the system's performance.
Keywords	enthalpy ; heat ; latent heat ; mass flow ; models ; nanoparticles ; phase transition ; renewable energy sources ; solar radiation ; thermal conductivity ; thermal energy
Language	English
Dates of publication	2022-11
Size	p. 745-758.
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	2001449-1
ISSN	1879-0682 ; 0960-1481
ISSN (online)	1879-0682
ISSN	0960-1481
DOI	10.1016/j.renene.2022.09.029
Database	NAL-Catalogue (AGRICOLA)

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