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Article: A systematic review of non-pharmacological interventions used for pain relief after orthopedic surgical procedures.

Fan, Meifen / Chen, Zheying

2020 Volume 20, Issue 5, Page(s) 36

Abstract: The purpose of the present review was to evaluate the available evidence on the efficacy of various non-pharmacological interventions to relieve pain after orthopedic surgical procedures. An electronic search of the PubMed, Embase and Cochrane library ... ...

Abstract	The purpose of the present review was to evaluate the available evidence on the efficacy of various non-pharmacological interventions to relieve pain after orthopedic surgical procedures. An electronic search of the PubMed, Embase and Cochrane library databases was performed to retrieve studies of all types assessing the role of non-pharmacological interventions for pain relief after orthopedic surgical procedures. The included studies were required to assess pain outcomes using a validated measurement index, such as the Visual Analog Scale. The quality of randomized control trials (RCTs) was assessed using the Cochrane tool, while the ROBINS-I tool was used for non-RCTs. A total of five studies were included, namely three RCTs and two non-RCTs. The included studies used relaxation therapy, guided imagery, music and audio-visual distraction for pain management. There was considerable heterogeneity concerning study participants and types of intervention, which precluded a meta-analysis. Overall, all studies reported a significant beneficial effect of non-pharmacological interventions for pain relief. To conclude, current evidence from a limited number of studies indicates there may be a potential role of non-pharmacological interventions, including relaxation therapy, guided imagery, music and audio-visual distraction, in pain management of patients after orthopedic surgery. Owing to considerable heterogeneity and risk of bias in the included studies, strong conclusions cannot be drawn. Further high-quality RCTs assessing the role of such non-pharmacological techniques of pain management are required to strengthen the current evidence.
Language	English
Publishing date	2020-09-01
Publishing country	Greece
Document type	Journal Article
ZDB-ID	2683844-8
ISSN	1792-1015 ; 1792-0981
ISSN (online)	1792-1015
ISSN	1792-0981
DOI	10.3892/etm.2020.9163
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Article: New material of the Early Pleistocene spiral horned antelope spirocerus (Artiodactyla, Mammalia) from North China and discussion on its evolution

Bai, Weipeng / Dong, Wei / Zhang, Limin / Wei, Qi / Liu, Wenhui / Chen, Zheying

Quaternary international. 2019 July 10, v. 522

2019

Abstract: The taxonomic and phylogenetic positions of spiral horned antelope Spirocerus have been controversial since its first discovery in Central Asia and with the discovery of more and more fossil specimens and localities in Central and East Asia. New material ...

Abstract	The taxonomic and phylogenetic positions of spiral horned antelope Spirocerus have been controversial since its first discovery in Central Asia and with the discovery of more and more fossil specimens and localities in Central and East Asia. New material of Spirocerus wongi were recently identified from the fossil specimens collected from Nihewan Formation at Shuichongkou along Xinyaozi ravine of Tianzhen County, Shanxi Province in North China. Taxonomic study shows that three species of Spirocerus can be regarded valid, i.e. S kiakhtensis, S. wongi and S. peii. Phylogenetic analyses indicates that they form a distinct clade closer to Bovinae than to Antilopinae, and Spirocerus can be placed in Bovinae rather than in Antilopinae. S. kiakhtensis might evolve from a Gazellospira-like form migrated from Europe to Central Asia in the Pliocene, then dispersed into northern China in the Early Pleistocene and evolved into S. wongi and S. peii. S. wongi dispersed further into northwestern and central China in the Early Pleistocene and disappeared in the Middle Pleistocene. S. peii ranged only in northern China in the Middle Pleistocene. After dispersion into northwestern and northeastern China in the Late Pleistocene, S. kiakhtensis disappeared near the end of the Pleistocene.
Keywords	Artiodactyla ; Pleistocene epoch ; Pliocene epoch ; antelopes ; fossils ; phylogeny ; Central Asia ; China ; Europe
Language	English
Dates of publication	2019-0710
Size	p. 94-102.
Publishing place	Elsevier Ltd
Document type	Article
ISSN	1040-6182
DOI	10.1016/j.quaint.2019.06.029
Database	NAL-Catalogue (AGRICOLA)

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Article: New material of the Early Pleistocene Elaphurus (Artiodactyla, Mammalia) from North China and discussion on taxonomy of Elaphurus

Dong, Wei / Bai, Weipeng / Bai, Yongbing / Chen, Zheying / Liu, Wenhui / Wei, Qi / Wu, Yongchun / Zhang, Limin

Quaternary international. 2019 June 10, v. 519

2019

Abstract: Many fossil Elaphurus have been discovered in East Asia and some in Central Asia since the discovery of the first fossil E. bifurcatus of the genus from Nihewan Basin in the 1920s. Some of them are well preserved, but some others are fragmental and it ... ...

Abstract	Many fossil Elaphurus have been discovered in East Asia and some in Central Asia since the discovery of the first fossil E. bifurcatus of the genus from Nihewan Basin in the 1920s. Some of them are well preserved, but some others are fragmental and it makes some identifications doubtful. Two Elaphurus were identified in recent study based on the unstudied material of fossil deer unearthed from Taijiaping, Tianzhen, Shanxi Province in North China. The taxonomy of Elaphurus was consequently discussed and it is recommended to classify the genus into four species with eight subspecies. Elaphurus davidianus predavidianus subsp. nov. distributed in North China and Taiwan in the Early Pleistocene. E. davidianus tamaensis is a geographic subspecies of the Early Pleistocene in Japan. E. d. menziesianus derived from E. d. predavidianus and distributed in North, Northeast and East China including Taiwan, as well as in Japan, from the Middle Pleistocene to the Holocene and E. d. davidianus restricted in North and East China probably since recent thousands years ago. E. bifurcatus bifurcatus and E. b. shikamai existed in the Early Pleistocene in North China and Japan respectively. The probable ancestor of E. bifurcatus is Elaphurus eleonorae from the Early Pleistocene of Kuruksay, Tadjikistan in Central Asia. The Early Pleistocene E. chinnaniensis chinnaniensis and E. c. lantianensis ranged in North China only and with dubious generic status.
Keywords	ancestry ; basins ; deer ; Elaphurus davidianus ; fossils ; Holocene epoch ; new subspecies ; Pleistocene epoch ; Central Asia ; China ; Japan ; Taiwan
Language	English
Dates of publication	2019-0610
Size	p. 113-121.
Publishing place	Elsevier Ltd
Document type	Article
ISSN	1040-6182
DOI	10.1016/j.quaint.2018.05.015
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Transforming Growth Factor-β in Thoracic Aortic Aneurysms: Good, Bad, or Irrelevant?

Daugherty, Alan / Chen, Zheying / Sawada, Hisashi / Rateri, Debra L / Sheppard, Mary B

Journal of the American Heart Association

2017 Volume 6, Issue 1

MeSH term(s)	Aorta, Thoracic ; Aortic Aneurysm, Thoracic ; Genetic Predisposition to Disease ; Humans ; Transforming Growth Factor beta/genetics ; Transforming Growth Factors
Chemical Substances	Transforming Growth Factor beta ; Transforming Growth Factors (76057-06-2)
Language	English
Publishing date	2017-01-24
Publishing country	England
Document type	Editorial ; Research Support, N.I.H., Extramural ; Comment
ZDB-ID	2653953-6
ISSN	2047-9980 ; 2047-9980
ISSN (online)	2047-9980
ISSN	2047-9980
DOI	10.1161/JAHA.116.005221
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Article ; Online: Combined therapy with GABA and proinsulin/alum acts synergistically to restore long-term normoglycemia by modulating T-cell autoimmunity and promoting β-cell replication in newly diabetic NOD mice.

Tian, Jide / Dang, Hoa / Nguyen, An Viet / Chen, Zheying / Kaufman, Daniel L

Diabetes

2014 Volume 63, Issue 9, Page(s) 3128–3134

Abstract: Antigen-based therapies (ABTs) fail to restore normoglycemia in newly diabetic NOD mice, perhaps because too few β-cells remain by the time that ABT-induced regulatory responses arise and spread. We hypothesized that combining a fast-acting anti- ... ...

Abstract	Antigen-based therapies (ABTs) fail to restore normoglycemia in newly diabetic NOD mice, perhaps because too few β-cells remain by the time that ABT-induced regulatory responses arise and spread. We hypothesized that combining a fast-acting anti-inflammatory agent with an ABT could limit pathogenic responses while ABT-induced regulatory responses arose and spread. γ-Aminobutyric acid (GABA) administration can inhibit inflammation, enhance regulatory T-cell (Treg) responses, and promote β-cell replication in mice. We examined the effect of combining a prototypic ABT, proinsulin/alum, with GABA treatment in newly diabetic NOD mice. Proinsulin/alum monotherapy failed to correct hyperglycemia, while GABA monotherapy restored normoglycemia for a short period. Combined treatment restored normoglycemia in the long term with apparent permanent remission in some mice. Proinsulin/alum monotherapy induced interleukin (IL)-4- and IL-10-secreting T-cell responses that spread to other β-cell autoantigens. GABA monotherapy induced moderate IL-10 (but not IL-4) responses to β-cell autoantigens. Combined treatment synergistically reduced spontaneous type 1 T-helper cell responses to autoantigens, ABT-induced IL-4 and humoral responses, and insulitis, but enhanced IL-10 and Treg responses and promoted β-cell replication in the islets. Thus, combining ABT with GABA can inhibit pathogenic T-cell responses, induce Treg responses, promote β-cell replication, and effectively restore normoglycemia in newly diabetic NOD mice. Since these treatments appear safe for humans, they hold promise for type 1 diabetes intervention.
MeSH term(s)	Alum Compounds/administration & dosage ; Animals ; Autoimmunity/drug effects ; Autoimmunity/immunology ; Blood Glucose/metabolism ; Cell Division/drug effects ; Diabetes Mellitus, Type 1/drug therapy ; Diabetes Mellitus, Type 1/immunology ; Drug Therapy, Combination ; Female ; Interleukin-10/biosynthesis ; Interleukin-4/biosynthesis ; Mice ; Mice, Inbred NOD ; Proinsulin/administration & dosage ; T-Lymphocytes, Regulatory/immunology
Chemical Substances	Alum Compounds ; Blood Glucose ; Interleukin-10 (130068-27-8) ; Interleukin-4 (207137-56-2) ; aluminum sulfate (34S289N54E) ; Proinsulin (9035-68-1)
Language	English
Publishing date	2014-08-22
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	80085-5
ISSN	1939-327X ; 0012-1797
ISSN (online)	1939-327X
ISSN	0012-1797
DOI	10.2337/db13-1385
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Article ; Online: γ-Aminobutyric acid regulates both the survival and replication of human β-cells.

Tian, Jide / Dang, Hoa / Chen, Zheying / Guan, Alice / Jin, Yingli / Atkinson, Mark A / Kaufman, Daniel L

Diabetes

2013 Volume 62, Issue 11, Page(s) 3760–3765

Abstract: γ-Aminobutyric acid (GABA) has been shown to inhibit apoptosis of rodent β-cells in vitro. In this study, we show that activation of GABAA receptors (GABAA-Rs) or GABAB-Rs significantly inhibits oxidative stress-related β-cell apoptosis and preserves ... ...

Abstract	γ-Aminobutyric acid (GABA) has been shown to inhibit apoptosis of rodent β-cells in vitro. In this study, we show that activation of GABAA receptors (GABAA-Rs) or GABAB-Rs significantly inhibits oxidative stress-related β-cell apoptosis and preserves pancreatic β-cells in streptozotocin-rendered hyperglycemic mice. Moreover, treatment with GABA, or a GABAA-R- or GABAB-R-specific agonist, inhibited human β-cell apoptosis following islet transplantation into NOD/scid mice. Accordingly, activation of GABAA-Rs and/or GABAB-Rs may be a useful adjunct therapy for human islet transplantation. GABA-R agonists also promoted β-cell replication in hyperglycemic mice. While a number of agents can promote rodent β-cell replication, most fail to provide similar activities with human β-cells. In this study, we show that GABA administration promotes β-cell replication and functional recovery in human islets following implantation into NOD/scid mice. Human β-cell replication was induced by both GABAA-R and GABAB-R activation. Hence, GABA regulates both the survival and replication of human β-cells. These actions, together with the anti-inflammatory properties of GABA, suggest that modulation of peripheral GABA-Rs may represent a promising new therapeutic strategy for improving β-cell survival following human islet transplantation and increasing β-cells in patients with diabetes.
MeSH term(s)	Animals ; Apoptosis/drug effects ; Baclofen/pharmacology ; Cell Survival/drug effects ; Diabetes Mellitus, Experimental ; GABA-A Receptor Agonists/pharmacology ; Heterografts ; Humans ; Insulin-Secreting Cells/drug effects ; Insulin-Secreting Cells/pathology ; Islets of Langerhans Transplantation ; Male ; Mice ; Mice, Inbred NOD ; Muscimol/pharmacology ; Receptors, GABA-A/physiology ; gamma-Aminobutyric Acid/pharmacology
Chemical Substances	GABA-A Receptor Agonists ; Receptors, GABA-A ; Muscimol (2763-96-4) ; gamma-Aminobutyric Acid (56-12-2) ; Baclofen (H789N3FKE8)
Language	English
Publishing date	2013-08-30
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	80085-5
ISSN	1939-327X ; 0012-1797
ISSN (online)	1939-327X
ISSN	0012-1797
DOI	10.2337/db13-0931
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Article ; Online: A functional genomics screen identifying blood cell development genes in Drosophila by undergraduates participating in a course-based research experience.

Evans, Cory J / Olson, John M / Mondal, Bama Charan / Kandimalla, Pratyush / Abbasi, Ariano / Abdusamad, Mai M / Acosta, Osvaldo / Ainsworth, Julia A / Akram, Haris M / Albert, Ralph B / Alegria-Leal, Elitzander / Alexander, Kai Y / Ayala, Angelica C / Balashova, Nataliya S / Barber, Rebecca M / Bassi, Harmanjit / Bennion, Sean P / Beyder, Miriam / Bhatt, Kush V /

Bhoot, Chinmay / Bradshaw, Aaron W / Brannigan, Tierney G / Cao, Boyu / Cashell, Yancey Y / Chai, Timothy / Chan, Alex W / Chan, Carissa / Chang, Inho / Chang, Jonathan / Chang, Michael T / Chang, Patrick W / Chang, Stephen / Chari, Neel / Chassiakos, Alexander J / Chen, Iris E / Chen, Vivian K / Chen, Zheying / Cheng, Marsha R / Chiang, Mimi / Chiu, Vivian / Choi, Sharon / Chung, Jun Ho / Contreras, Liset / Corona, Edgar / Cruz, Courtney J / Cruz, Renae L / Dang, Jefferson M / Dasari, Suhas P / De La Fuente, Justin R O / Del Rio, Oscar M A / Dennis, Emily R / Dertsakyan, Petros S / Dey, Ipsita / Distler, Rachel S / Dong, Zhiqiao / Dorman, Leah C / Douglass, Mark A / Ehresman, Allysen B / Fu, Ivy H / Fua, Andrea / Full, Sean M / Ghaffari-Rafi, Arash / Ghani, Asmar Abdul / Giap, Bosco / Gill, Sonia / Gill, Zafar S / Gills, Nicholas J / Godavarthi, Sindhuja / Golnazarian, Talin / Goyal, Raghav / Gray, Ricardo / Grunfeld, Alexander M / Gu, Kelly M / Gutierrez, Natalia C / Ha, An N / Hamid, Iman / Hanson, Ashley / Hao, Celesti / He, Chongbin / He, Mengshi / Hedtke, Joshua P / Hernandez, Ysrael K / Hlaing, Hnin / Hobby, Faith A / Hoi, Karen / Hope, Ashley C / Hosseinian, Sahra M / Hsu, Alice / Hsueh, Jennifer / Hu, Eileen / Hu, Spencer S / Huang, Stephanie / Huang, Wilson / Huynh, Melanie / Javier, Carmen / Jeon, Na Eun / Ji, Sunjong / Johal, Jasmin / John, Amala / Johnson, Lauren / Kadakia, Saurin / Kakade, Namrata / Kamel, Sarah / Kaur, Ravinder / Khatra, Jagteshwar S / Kho, Jeffrey A / Kim, Caleb / Kim, Emily Jin-Kyung / Kim, Hee Jong / Kim, Hyun Wook / Kim, Jin Hee / Kim, Seong Ah / Kim, Woo Kyeom / Kit, Brian / La, Cindy / Lai, Jonathan / Lam, Vivian / Le, Nguyen Khoi / Lee, Chi Ju / Lee, Dana / Lee, Dong Yeon / Lee, James / Lee, Jason / Lee, Jessica / Lee, Ju-Yeon / Lee, Sharon / Lee, Terrence C / Lee, Victoria / Li, Amber J / Li, Jialing / Libro, Alexandra M / Lien, Irvin C / Lim, Mia / Lin, Jeffrey M / Liu, Connie Y / Liu, Steven C / Louie, Irene / Lu, Shijia W / Luo, William Y / Luu, Tiffany / Madrigal, Josef T / Mai, Yishan / Miya, Darron I / Mohammadi, Mina / Mohanta, Sayonika / Mokwena, Tebogo / Montoya, Tonatiuh / Mould, Dallas L / Murata, Mark R / Muthaiya, Janani / Naicker, Seethim / Neebe, Mallory R / Ngo, Amy / Ngo, Duy Q / Ngo, Jamie A / Nguyen, Anh T / Nguyen, Huy C X / Nguyen, Rina H / Nguyen, Thao T T / Nguyen, Vincent T / Nishida, Kevin / Oh, Seo-Kyung / Omi, Kristen M / Onglatco, Mary C / Almazan, Guadalupe Ortega / Paguntalan, Jahzeel / Panchal, Maharshi / Pang, Stephanie / Parikh, Harin B / Patel, Purvi D / Patel, Trisha H / Petersen, Julia E / Pham, Steven / Phan-Everson, Tien M / Pokhriyal, Megha / Popovich, Davis W / Quaal, Adam T / Querubin, Karl / Resendiz, Anabel / Riabkova, Nadezhda / Rong, Fred / Salarkia, Sarah / Sama, Nateli / Sang, Elaine / Sanville, David A / Schoen, Emily R / Shen, Zhouyang / Siangchin, Ken / Sibal, Gabrielle / Sin, Garuem / Sjarif, Jasmine / Smith, Christopher J / Soeboer, Annisa N / Sosa, Cristian / Spitters, Derek / Stender, Bryan / Su, Chloe C / Summapund, Jenny / Sun, Beatrice J / Sutanto, Christine / Tan, Jaime S / Tan, Nguon L / Tangmatitam, Parich / Trac, Cindy K / Tran, Conny / Tran, Daniel / Tran, Duy / Tran, Vina / Truong, Patrick A / Tsai, Brandon L / Tsai, Pei-Hua / Tsui, C Kimberly / Uriu, Jackson K / Venkatesh, Sanan / Vo, Maique / Vo, Nhat-Thi / Vo, Phuong / Voros, Timothy C / Wan, Yuan / Wang, Eric / Wang, Jeffrey / Wang, Michael K / Wang, Yuxuan / Wei, Siman / Wilson, Matthew N / Wong, Daniel / Wu, Elliott / Xing, Hanning / Xu, Jason P / Yaftaly, Sahar / Yan, Kimberly / Yang, Evan / Yang, Rebecca / Yao, Tony / Yeo, Patricia / Yip, Vivian / Yogi, Puja / Young, Gloria Chin / Yung, Maggie M / Zai, Alexander / Zhang, Christine / Zhang, Xiao X / Zhao, Zijun / Zhou, Raymond / Zhou, Ziqi / Abutouk, Mona / Aguirre, Brian / Ao, Chon / Baranoff, Alexis / Beniwal, Angad / Cai, Zijie / Chan, Ryan / Chien, Kenneth Chang / Chaudhary, Umar / Chin, Patrick / Chowdhury, Praptee / Dalie, Jamlah / Du, Eric Y / Estrada, Alec / Feng, Erwin / Ghaly, Monica / Graf, Rose / Hernandez, Eduardo / Herrera, Kevin / Ho, Vivien W / Honeychurch, Kaitlyn / Hou, Yurianna / Huang, Jo M / Ishii, Momoko / James, Nicholas / Jang, Gah-Eun / Jin, Daphne / Juarez, Jesse / Kesaf, Ayse Elif / Khalsa, Sat Kartar / Kim, Hannah / Kovsky, Jenna / Kuang, Chak Lon / Kumar, Shraddha / Lam, Gloria / Lee, Ceejay / Lee, Grace / Li, Li / Lin, Joshua / Liu, Josephine / Ly, Janice / Ma, Austin / Markovic, Hannah / Medina, Cristian / Mungcal, Jonelle / Naranbaatar, Bilguudei / Patel, Kayla / Petersen, Lauren / Phan, Amanda / Phung, Malcolm / Priasti, Nadiyah / Ruano, Nancy / Salim, Tanveer / Schnell, Kristen / Shah, Paras / Shen, Jinhua / Stutzman, Nathan / Sukhina, Alisa / Tian, Rayna / Vega-Loza, Andrea / Wang, Joyce / Wang, Jun / Watanabe, Rina / Wei, Brandon / Xie, Lillian / Ye, Jessica / Zhao, Jeffrey / Zimmerman, Jill / Bracken, Colton / Capili, Jason / Char, Andrew / Chen, Michel / Huang, Pingdi / Ji, Sena / Kim, Emily / Kim, Kenneth / Ko, Julie / Laput, Sean Louise G / Law, Sam / Lee, Sang Kuk / Lee, Olivia / Lim, David / Lin, Eric / Marik, Kyle / Mytych, Josh / O'Laughlin, Andie / Pak, Jensen / Park, Claire / Ryu, Ruth / Shinde, Ashwin / Sosa, Manny / Waite, Nick / Williams, Mane / Wong, Richard / Woo, Jocelyn / Woo, Jonathan / Yepuri, Vishaal / Yim, Dorothy / Huynh, Dan / Wijiewarnasurya, Dinali / Shapiro, Casey / Levis-Fitzgerald, Marc / Jaworski, Leslie / Lopatto, David / Clark, Ira E / Johnson, Tracy / Banerjee, Utpal

G3 (Bethesda, Md.)

2021 Volume 11, Issue 1

Abstract: Undergraduate students participating in the UCLA Undergraduate Research Consortium for Functional Genomics (URCFG) have conducted a two-phased screen using RNA interference (RNAi) in combination with fluorescent reporter proteins to identify genes ... ...

Abstract	Undergraduate students participating in the UCLA Undergraduate Research Consortium for Functional Genomics (URCFG) have conducted a two-phased screen using RNA interference (RNAi) in combination with fluorescent reporter proteins to identify genes important for hematopoiesis in Drosophila. This screen disrupted the function of approximately 3500 genes and identified 137 candidate genes for which loss of function leads to observable changes in the hematopoietic development. Targeting RNAi to maturing, progenitor, and regulatory cell types identified key subsets that either limit or promote blood cell maturation. Bioinformatic analysis reveals gene enrichment in several previously uncharacterized areas, including RNA processing and export and vesicular trafficking. Lastly, the participation of students in this course-based undergraduate research experience (CURE) correlated with increased learning gains across several areas, as well as increased STEM retention, indicating that authentic, student-driven research in the form of a CURE represents an impactful and enriching pedagogical approach.
MeSH term(s)	Animals ; Blood Cells ; Drosophila/genetics ; Genomics/education ; Humans ; Students ; Universities
Language	English
Publishing date	2021-02-12
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2629978-1
ISSN	2160-1836 ; 2160-1836
ISSN (online)	2160-1836
ISSN	2160-1836
DOI	10.1093/g3journal/jkaa028
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Article: A systematic review of non-pharmacological interventions used for pain relief after orthopedic surgical procedures.

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Article: New material of the Early Pleistocene spiral horned antelope spirocerus (Artiodactyla, Mammalia) from North China and discussion on its evolution

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Article: New material of the Early Pleistocene Elaphurus (Artiodactyla, Mammalia) from North China and discussion on taxonomy of Elaphurus

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Article ; Online: Transforming Growth Factor-β in Thoracic Aortic Aneurysms: Good, Bad, or Irrelevant?

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Article ; Online: Combined therapy with GABA and proinsulin/alum acts synergistically to restore long-term normoglycemia by modulating T-cell autoimmunity and promoting β-cell replication in newly diabetic NOD mice.

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Article ; Online: γ-Aminobutyric acid regulates both the survival and replication of human β-cells.

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Article ; Online: A functional genomics screen identifying blood cell development genes in Drosophila by undergraduates participating in a course-based research experience.

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