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  1. AU="Chen, Zipeng"
  2. AU=Bilinski Alyssa
  3. AU="Honboh, Takuya"
  4. AU=Dobie David Robertson
  5. AU=Gagnon R F
  6. AU="Suthaharan, Praveen"
  7. AU=Freeman Alexandra F
  8. AU="Szabo, Gergo"

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  1. Artikel ; Online: Difference-Guided Representation Learning Network for Multivariate Time-Series Classification.

    Ma, Qianli / Chen, Zipeng / Tian, Shuai / Ng, Wing W Y

    IEEE transactions on cybernetics

    2022  Band 52, Heft 6, Seite(n) 4717–4727

    Abstract: Multivariate time series (MTSs) are widely found in many important application fields, for example, medicine, multimedia, manufacturing, action recognition, and speech recognition. The accurate classification of MTS has become an important research topic. ...

    Abstract Multivariate time series (MTSs) are widely found in many important application fields, for example, medicine, multimedia, manufacturing, action recognition, and speech recognition. The accurate classification of MTS has become an important research topic. Traditional MTS classification methods do not explicitly model the temporal difference information of time series, which is, in fact, important and reflects the dynamic evolution information. In this article, the difference-guided representation learning network (DGRL-Net) is proposed to guide the representation learning of time series by dynamic evolution information. The DGRL-Net consists of a difference-guided layer and a multiscale convolutional layer. First, in the difference-guided layer, we propose a difference gating LSTM to model the time dependency and dynamic evolution of the time series to obtain feature representations of both raw and difference series. Then, these two representations are used as two input channels of the multiscale convolutional layer to extract multiscale information. Extensive experiments demonstrate that the proposed model outperforms state-of-the-art methods on 18 MTS benchmark datasets and achieves competitive results on two skeleton-based action recognition datasets. Furthermore, the ablation study and visualized analysis are designed to verify the effectiveness of the proposed model.
    Mesh-Begriff(e) Learning ; Time Factors
    Sprache Englisch
    Erscheinungsdatum 2022-06-16
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2168-2275
    ISSN (online) 2168-2275
    DOI 10.1109/TCYB.2020.3034755
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Spider-Silk-Inspired Nanocomposite Polymers for Durable Daytime Radiative Cooling.

    Yao, Pengcheng / Chen, Zipeng / Liu, Tianji / Liao, Xiangbiao / Yang, Zhengwei / Li, Jinlei / Jiang, Yi / Xu, Ning / Li, Wei / Zhu, Bin / Zhu, Jia

    Advanced materials (Deerfield Beach, Fla.)

    2022  , Seite(n) e2208236

    Abstract: Passive daytime radiative cooling (PDRC) materials, that strongly reflect sunlight and emit thermal radiation to outer space, demonstrate great potential in energy-saving for sustainable development. Particularly, polymer-based PDRC materials, with ... ...

    Abstract Passive daytime radiative cooling (PDRC) materials, that strongly reflect sunlight and emit thermal radiation to outer space, demonstrate great potential in energy-saving for sustainable development. Particularly, polymer-based PDRC materials, with advantages of easy-processing, low cost, and outstanding cooling performance, have attracted intense attention. However, just like other polymer devices (for example polymer solar cells) working under sunlight, the issue of durability related to mechanical and UV properties needs to be addressed for large-scale practical applications. Here, a spider-silk-inspired design of nanocomposite polymers with potassium titanate (K
    Sprache Englisch
    Erscheinungsdatum 2022-10-18
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202208236
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: TSPAN31 suppresses cell proliferation in human cervical cancer through down-regulation of its antisense pairing with CDK4.

    Xia, Yingjie / Deng, Yuanfei / Zhou, Yuting / Li, Dan / Sun, Xuemeng / Gu, Lei / Chen, Zipeng / Zhao, Qing

    Cell biochemistry and function

    2020  Band 38, Heft 5, Seite(n) 660–668

    Abstract: Natural antisense transcripts (NAT) are prevalent phenomena in the mammalian genome and play significant regulatory roles in gene expression. While new insights into NAT continue to be revealed, their exact function and their underlying mechanisms in ... ...

    Abstract Natural antisense transcripts (NAT) are prevalent phenomena in the mammalian genome and play significant regulatory roles in gene expression. While new insights into NAT continue to be revealed, their exact function and their underlying mechanisms in human cancer remain largely unclear. We identified a NAT of CDK4, referred to TSPAN31, which inhibits CDK4 mRNA and protein expression in human cervical cancer by targeting the 3'-untranslated region (3'-UTR) of the CDK4 mRNA. Furthermore, silencing the expression of the TSPAN31 mRNA rescued the TSPAN31 3'-UTR- or the TSPAN31 full-length-induced decrease in CDK4 expression. Noteworthy, we discovered that TSPAN31, as a member of the tetraspanin family, suppressed cell proliferation by down-regulating its antisense pairing with CDK4 and decreasing retinoblastoma protein phosphorylation in human cervical cancer. Therefore, the results of the present study suggest that TSPAN31 may serve as a potential molecular target for the development of novel anti-cancer agents. SIGNIFICANCE OF THE STUDY: Natural antisense transcripts are widely found in the genome and play an important role in the growth and development of cells. TSPAN31 is natural antisense transcript, and CDK4 is an important gene in the regulation of the cell cycle. Therefore, TSPAN31 and CDK4 have great significance in the study of tumour therapeutic targets.
    Mesh-Begriff(e) Cell Proliferation ; Cell Survival ; Cells, Cultured ; Cyclin-Dependent Kinase 4/genetics ; Cyclin-Dependent Kinase 4/metabolism ; Down-Regulation ; Female ; Humans ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Tetraspanins/metabolism ; Uterine Cervical Neoplasms/metabolism ; Uterine Cervical Neoplasms/pathology
    Chemische Substanzen RNA, Messenger ; TSPAN31 protein, human ; Tetraspanins ; CDK4 protein, human (EC 2.7.11.22) ; Cyclin-Dependent Kinase 4 (EC 2.7.11.22)
    Sprache Englisch
    Erscheinungsdatum 2020-03-23
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 283643-9
    ISSN 1099-0844 ; 0263-6484
    ISSN (online) 1099-0844
    ISSN 0263-6484
    DOI 10.1002/cbf.3526
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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