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  1. Book ; Online ; E-Book: RNA-Seq in Drug Discovery and Development

    Cheng, Feng / Morris, Robert

    (Drugs and the Pharmaceutical Sciences Series)

    2024  

    Abstract: The research and development process in modern drug discovery and development is a complex and challenging task. Using traditional biological test methods such as PCR to measure the expression levels or function of these genes is costly and time- ... ...

    Author's details edited by Feng Cheng and Robert Morris
    Series title Drugs and the Pharmaceutical Sciences Series
    Abstract "The research and development process in modern drug discovery and development is a complex and challenging task. Using traditional biological test methods such as PCR to measure the expression levels or function of these genes is costly and time-consuming. RNA-seq can measure the expression patterns of thousands of genes simultaneously and provide insights into functional pathways or regulations in biological processes, which has revolutionized the way biological scientists examine gene functions. This book addresses the various aspects of the RNA-seq technique, especially its application in drug discovery and development"--
    Keywords Drug development ; Small interfering RNA/Therapeutic use.
    Subject code 615.19
    Language English
    Size 1 online resource (279 pages)
    Publisher CRC Press
    Publishing place Boca Raton, FL
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-00-317402-7 ; 1-003-17402-7 ; 1-000-91825-4 ; 9781032004068 ; 978-1-00-317402-8 ; 978-1-003-17402-8 ; 978-1-000-91825-0 ; 1032004061
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Study on the extraction of aerosol information and its spatial-temporal changes based on PARASOL and CALIPSOL remote sensing data in the Yangtze River Delta

    CHENG Feng

    Acta Geodaetica et Cartographica Sinica, Vol 48, Iss 6, Pp 803-

    2019  Volume 803

    Keywords Mathematical geography. Cartography ; GA1-1776
    Language Chinese
    Publishing date 2019-06-01T00:00:00Z
    Publisher Surveying and Mapping Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: The tooth relic of the Buddha: The viewpoint from paleodontology and modern dentistry.

    Cheng, Feng-Chou / Chiang, Chun-Pin

    Journal of dental sciences

    2023  Volume 19, Issue 1, Page(s) 729–731

    Language English
    Publishing date 2023-11-11
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2213-8862
    ISSN (online) 2213-8862
    DOI 10.1016/j.jds.2023.10.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: IgG4-related sclerosing cholangitis: A case report.

    Hu, Haoran / Cheng, Feng

    Asian journal of surgery

    2023  Volume 46, Issue 7, Page(s) 2878–2879

    MeSH term(s) Humans ; Cholangitis, Sclerosing/diagnosis ; Immunoglobulin G ; Cholangiocarcinoma/diagnosis ; Bile Ducts, Intrahepatic ; Bile Duct Neoplasms/diagnosis ; Diagnosis, Differential
    Chemical Substances Immunoglobulin G
    Language English
    Publishing date 2023-02-01
    Publishing country Netherlands
    Document type Case Reports ; Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2023.01.090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Drug Repurposing Using FDA Adverse Event Reporting System (FAERS) Database.

    Morris, Robert / Cheng, Feng / Ali, Rahinatu

    Current drug targets

    2024  

    Abstract: Drug repurposing is an emerging approach to reassigning existing pre-approved therapies for new indications. The FDA Adverse Event Reporting System (FAERS) is a large database of over 28 million adverse event reports submitted by medical providers, ... ...

    Abstract Drug repurposing is an emerging approach to reassigning existing pre-approved therapies for new indications. The FDA Adverse Event Reporting System (FAERS) is a large database of over 28 million adverse event reports submitted by medical providers, patients, and drug manufacturers and provides extensive drug safety signal data. In this review, four common drug repurposing strategies using FAERS are described, including inverse signal detection for a single disease, drug-drug interactions that mitigate a target ADE, identifying drug-ADE pairs with opposing gene perturbation signatures and identifying drug-drug pairs with congruent gene perturbation signatures. The purpose of this review is to provide an overview of these different approaches to FAERS-based drug repurposing using existing successful applications in the literature. With the fast expansion of adverse drug event reports, FAERS-based drug repurposing represents a versatile and promising strategy for discovering new uses for existing therapies.
    Language English
    Publishing date 2024-04-02
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2064859-5
    ISSN 1873-5592 ; 1389-4501
    ISSN (online) 1873-5592
    ISSN 1389-4501
    DOI 10.2174/0113894501290296240327081624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Recent Progress of the Cellulose-Based Antibacterial Hydrogel.

    Sun, Ying / Wang, Jiayi / Li, Duanxin / Cheng, Feng

    Gels (Basel, Switzerland)

    2024  Volume 10, Issue 2

    Abstract: Cellulose-based antibacterial hydrogel has good biocompatibility, antibacterial performance, biodegradability, and other characteristics. It can be very compatible with human tissues and degradation, while its good water absorption and moisturizing ... ...

    Abstract Cellulose-based antibacterial hydrogel has good biocompatibility, antibacterial performance, biodegradability, and other characteristics. It can be very compatible with human tissues and degradation, while its good water absorption and moisturizing properties can effectively absorb wound exudates, keep the wound moist, and promote wound healing. In this paper, the structural properties, and physical and chemical cross-linking preparation methods of cellulose-based antibacterial hydrogels were discussed in detail, and the application of cellulose-based hydrogels in the antibacterial field was deeply studied. In general, cellulose-based antibacterial hydrogels, as a new type of biomaterial, have shown good potential in antimicrobial properties and have been widely used. However, there are still some challenges, such as optimizing the preparation process and performance parameters, improving the antibacterial and physical properties, broadening the application range, and evaluating safety. However, with the deepening of research and technological progress, it is believed that cellulose-based antibacterial hydrogels will be applied and developed in more fields in the future.
    Language English
    Publishing date 2024-01-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2813982-3
    ISSN 2310-2861 ; 2310-2861
    ISSN (online) 2310-2861
    ISSN 2310-2861
    DOI 10.3390/gels10020109
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Survey of the distribution of dental X-ray machines in Taiwan's hospitals.

    Cheng, Feng-Chou / Hu, Yu-Ting / Chiang, Chun-Pin

    Journal of dental sciences

    2024  Volume 19, Issue 2, Page(s) 1270–1273

    Language English
    Publishing date 2024-01-29
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2213-8862
    ISSN (online) 2213-8862
    DOI 10.1016/j.jds.2024.01.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The geographical distribution of physicians and dentists in the public health centers in Taiwan in 2022.

    Cheng, Feng-Chou / Tang, Li-Hua / Chiang, Chun-Pin

    Journal of dental sciences

    2024  Volume 19, Issue 2, Page(s) 1266–1269

    Language English
    Publishing date 2024-02-05
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2213-8862
    ISSN (online) 2213-8862
    DOI 10.1016/j.jds.2024.01.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Survey of the operating models of dental radiology in general hospitals in Taiwan.

    Cheng, Feng-Chou / Chen, Cheng-Hsueh / Chiang, Chun-Pin

    Journal of dental sciences

    2024  Volume 19, Issue 2, Page(s) 1285–1287

    Language English
    Publishing date 2024-01-18
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2213-8862
    ISSN (online) 2213-8862
    DOI 10.1016/j.jds.2024.01.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: How to become a dental equipment technician and overview of the dental equipment repair industry in Taiwan.

    Cheng, Feng-Chou / Wang, Ling-Hsia / Chiang, Chun-Pin

    Journal of dental sciences

    2024  Volume 19, Issue 2, Page(s) 1274–1279

    Language English
    Publishing date 2024-01-23
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2213-8862
    ISSN (online) 2213-8862
    DOI 10.1016/j.jds.2024.01.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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