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  1. Article ; Online: Our choice is not binary between lockdown and herd immunity.

    Cheng, K K

    BMJ (Clinical research ed.)

    2020  Volume 371, Page(s) m4051

    MeSH term(s) Adult ; Age Factors ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/immunology ; Coronavirus Infections/mortality ; Coronavirus Infections/prevention & control ; Humans ; Immunity, Herd ; Infection Control ; Middle Aged ; Pandemics/prevention & control ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/immunology ; Pneumonia, Viral/mortality ; Pneumonia, Viral/prevention & control ; Young Adult
    Keywords covid19
    Language English
    Publishing date 2020-10-22
    Publishing country England
    Document type Letter
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.m4051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Challenges in screening and general health checks in China.

    Gong, Wenjie / Cheng, K K

    The Lancet. Public health

    2022  Volume 7, Issue 12, Page(s) e989–e990

    MeSH term(s) Humans ; Research ; Mass Screening ; China
    Language English
    Publishing date 2022-11-30
    Publishing country England
    Document type Journal Article
    ISSN 2468-2667
    ISSN (online) 2468-2667
    DOI 10.1016/S2468-2667(22)00207-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The effects of obstructing the blood-flow through the pulmonary vessels: an experimental study in rats.

    CHENG, K K

    Quarterly journal of experimental physiology and cognate medical sciences

    2014  Volume 36, Issue 2, Page(s) 101–117

    MeSH term(s) Animals ; Hemodynamics ; Lung/surgery ; Pulmonary Artery ; Rats
    Language English
    Publishing date 2014-01-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 80192-6
    ISSN 0033-5541 ; 0144-8757 ; 0370-2901
    ISSN 0033-5541 ; 0144-8757 ; 0370-2901
    DOI 10.1113/expphysiol.1951.sp000961
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Covid-19: risk factors for severe disease and death.

    Jordan, Rachel E / Adab, Peymane / Cheng, K K

    BMJ (Clinical research ed.)

    2020  Volume 368, Page(s) m1198

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; Retrospective Studies ; Risk Factors ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-03-26
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.m1198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Let us not forget the mask in our attempts to stall the spread of COVID-19.

    Leung, C C / Lam, T H / Cheng, K K

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2020  Volume 24, Issue 4, Page(s) 364–366

    Keywords covid19
    Language English
    Publishing date 2020-04-14
    Publishing country France
    Document type Editorial
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.20.0124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Barriers and facilitators for referring women with positive perinatal depression screening results in China: a qualitative study.

    Xue, Wenqing / Cheng, K K / Liu, Lu / Li, Qiao / Jin, Xin / Yi, Jingmin / Gong, Wenjie

    BMC pregnancy and childbirth

    2023  Volume 23, Issue 1, Page(s) 230

    Abstract: Background: Timely screening and referral can improve the outcomes of perinatal depression (PND). However, uptake rates of referral after PND screening are low in China and the reasons are unclear. The aim of this article is to explore the barriers and ... ...

    Abstract Background: Timely screening and referral can improve the outcomes of perinatal depression (PND). However, uptake rates of referral after PND screening are low in China and the reasons are unclear. The aim of this article is to explore the barriers and facilitators for referring women with positive results of PND screening in the Chinese primary maternal health care system.
    Methods: Qualitative data were collected from four primary health centers located in four different provinces of China. Each of the four investigators conducted 30 days of participant observations in the primary health centers from May to August 2020. Data were collected via participant observations and semi-structured in-depth interviews with new mothers who had positive results of PND screening, their family members, and primary health providers. Two investigators analyzed qualitative data independently. A thematic analysis was conducted, and data were framed using the social ecological model.
    Results: A total of 870 hours of observation and 46 interviews were carried out. Five themes were identified: individual (new mothers' knowledge of PND, perceived need to seek help), interpersonal (new mothers' attitudes towards providers, family support), institutional (providers' perception of PND, lack of training, time constraints), community (accessibility to mental health services, practical factors), and public policy (policy requirements, stigma).
    Conclusions: The likelihood of new mothers accepting PND referral is related to factors in five areas. Intervention strategies can be developed around these themes and may include educating new mothers and their families about PND, training primary health providers to improve their awareness of condition and indication for referral, building mental health support in routine postpartum home visits, and providing support through mobile technology.
    MeSH term(s) Female ; Humans ; Pregnancy ; Depression ; Maternal Health Services ; Mental Health ; Mothers/psychology ; Qualitative Research ; China ; Health Services Accessibility ; Referral and Consultation
    Language English
    Publishing date 2023-04-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059869-5
    ISSN 1471-2393 ; 1471-2393
    ISSN (online) 1471-2393
    ISSN 1471-2393
    DOI 10.1186/s12884-023-05532-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Prevalence of and optimal screening tool for postpartum depression in a community-based population in China.

    Zeng, Zhen / Li, Qiao / Caine, Eric D / Takwoingi, Yemisi / Zhong, Baoliang / Tong, Yongsheng / Cheng, K K / Gong, Wenjie

    Journal of affective disorders

    2023  Volume 348, Page(s) 191–199

    Abstract: Background: Postpartum depression (PPD) is an important public health problem worldwide. China is planning to launch PPD screening in community settings, but there are questions on the community prevalence of PPD and validated screening tools.: ... ...

    Abstract Background: Postpartum depression (PPD) is an important public health problem worldwide. China is planning to launch PPD screening in community settings, but there are questions on the community prevalence of PPD and validated screening tools.
    Methods: We sought to recruit all eligible new mothers during postnatal home visits in two districts of Changsha, China, and after informed consent, screened them for PPD using three self-administered questionnaires-the Edinburgh Postpartum Depression Scale (EPDS), the Patient Health Questionnaire (PHQ-9), and Whooley Questions for Depression Screening. Video structured diagnostic interviews were performed online according to Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) by qualified specialists who were blinded to screening results. Optimal screening was determined based on the acceptability of scales and diagnostic accuracy metrics including sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV).
    Results: Out of 3004 eligible women, 2730 (90.9 %) completed the screening questionnaires. Among those screened, the video structured diagnostic interview was administered to 1862 (68.2 %) and 62 (3.3 %) were diagnosed with a current depressive condition. The optimal screening approach involved combining Whooley Questions (at least one "yes") with EPDS (cutoff >10) in series, with sensitivity of 0.76 (95 % CI 0.63 to 0.85), specificity of 0.93 (0.92 to 0.94), PPV of 0.28 (0.21 to 0.36) and NPV of 0.99 (0.98 to 1.00).
    Limitations: Due to the regional sample and exclusion of mothers with telephone contact rather than home visits, our findings may not be fully generalizable to the entire population.
    Conclusions: The prevalence of PPD among women in this sample was substantially lower than those reported in previous studies in China, the majority of which used screen positivity in measuring prevalence. Combining Whooley Questions with EPDS in series is the most optimal screening approach in this population, though this would still result in a high number of false positives at current prevalence.
    MeSH term(s) Female ; Humans ; Depression, Postpartum/diagnosis ; Depression, Postpartum/epidemiology ; Depression, Postpartum/prevention & control ; Sensitivity and Specificity ; Mass Screening/methods ; Prevalence ; Psychiatric Status Rating Scales
    Language English
    Publishing date 2023-12-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2023.12.046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Circulating Tumour DNA Detection By The Urine-Informed Analysis Of Archival Serum Samples From Muscle-Invasive Bladder Cancer Patients.

    BinHumaid, Faisal S / Goel, Anshita / Gordon, Naheema S / Abbotts, Ben / Cheng, K K / Zeegers, Maurice P / James, Nicholas D / Altaweel, Waleed M / Seyam, Raouf M / Meyer, Brian F / Arnold, Roland / Ward, Douglas G / Bryan, Richard T

    European urology

    2024  Volume 85, Issue 5, Page(s) 508–509

    MeSH term(s) Humans ; Circulating Tumor DNA/genetics ; Urinary Bladder Neoplasms/pathology ; Biomarkers, Tumor/genetics ; Muscles/pathology
    Chemical Substances Circulating Tumor DNA ; Biomarkers, Tumor
    Language English
    Publishing date 2024-02-01
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2024.01.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Covid-19: why is the UK government ignoring WHO's advice?

    Pollock, Allyson M / Roderick, Peter / Cheng, K K / Pankhania, Bharat

    BMJ (Clinical research ed.)

    2020  Volume 368, Page(s) m1284

    MeSH term(s) Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Communicable Disease Control ; Contact Tracing ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Disease Outbreaks ; Evidence-Based Medicine ; Humans ; Laboratories ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; Public Health ; SARS-CoV-2 ; State Medicine/organization & administration ; United Kingdom/epidemiology ; World Health Organization
    Keywords covid19
    Language English
    Publishing date 2020-03-30
    Publishing country England
    Document type Editorial
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.m1284
    Database MEDical Literature Analysis and Retrieval System OnLINE

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