Article: MAIT Cells Modulate Innate Immune Cells and Inhibit Colon Cancer Growth.
bioRxiv : the preprint server for biology
2024
Abstract: Mucosal-associated invariant T (MAIT) cells are innate-like T cells that can be activated by microbial antigens and cytokines and are abundant in mucosal tissues including the colon. MAIT cells have cytotoxic and pro-inflammatory functions and have ... ...
| Abstract | Mucosal-associated invariant T (MAIT) cells are innate-like T cells that can be activated by microbial antigens and cytokines and are abundant in mucosal tissues including the colon. MAIT cells have cytotoxic and pro-inflammatory functions and have potentials for use as adoptive cell therapy. However, studies into their anti-cancer activity, including their role in colon cancer, are limited. Using an animal model of colon cancer, we show that peritumoral injection of |
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| Language | English |
| Publishing date | 2024-02-02 |
| Publishing country | United States |
| Document type | Preprint |
| DOI | 10.1101/2024.01.16.575894 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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