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  1. Article: [Hospital Safety Climate and Nursing Staff Mental Health: The Example of Workplace Violence].

    Cheng, Wan-Ju / Pien, Li-Chung

    Hu li za zhi The journal of nursing

    2022  Volume 69, Issue 5, Page(s) 21–26

    Abstract: Workplace violence is recognized as a serious psychosocial work hazard in the workplace. Nurses face higher risks of workplace violence and poor mental health than other medical professionals. In addition to addressing personal factors, workplace ... ...

    Abstract Workplace violence is recognized as a serious psychosocial work hazard in the workplace. Nurses face higher risks of workplace violence and poor mental health than other medical professionals. In addition to addressing personal factors, workplace violence should be understood and managed in the context of the organizational climate. In this article, the definition and types of workplace violence and a socio-ecological perspective on workplace violence are introduced. In addition, the prevalence and impact on mental health of workplace violence are described. Lastly, the concept of safety climate and its influence on mental health are proposed. We hope this article provides readers with a better understanding of workplace violence and a contextual perspective on this issue. In addition to understanding workplace violence and learning coping strategies and skills, hospital managers should promote a positive climate of safety to reduce the occurrence of workplace violence and the impact of workplace violence on nurses.
    MeSH term(s) Hospitals ; Humans ; Mental Health ; Nursing Staff ; Organizational Culture ; Workplace Violence/prevention & control ; Workplace Violence/psychology
    Language Chinese
    Publishing date 2022-09-20
    Publishing country China (Republic : 1949- )
    Document type Journal Article
    ISSN 0047-262X
    ISSN 0047-262X
    DOI 10.6224/JN.202210_69(5).04
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  2. Article ; Online: Gender- and age-specific associations between psychosocial work conditions and perceived work sustainability in the general working population in Taiwan.

    Cheng, Yawen / Li, Yi-Jing / Cheng, Wan-Ju

    PloS one

    2023  Volume 18, Issue 10, Page(s) e0293282

    Abstract: Objectives: One aspect of work sustainability pertains to workers' intention to remain in their current job until reaching retirement age. Various adverse working conditions are expected to diminish work sustainability among different social groups. ... ...

    Abstract Objectives: One aspect of work sustainability pertains to workers' intention to remain in their current job until reaching retirement age. Various adverse working conditions are expected to diminish work sustainability among different social groups. This study aims to examine these associations across gender and age groups.
    Methods: The study participants were 19,152 economically-active adults in a national survey conducted in Taiwan. Information concerning psychosocial working conditions were obtained through interviews, using the Job Content Questionnaire. Work sustainability was evaluated by one question that asked whether the participants felt they would be able to do their current job until the age of 60. The association between psychosocial work conditions and work sustainability was examined by logistic regression analysis. We further performed stratified analysis to explore age and gender-specific associations.
    Results: We observed that 14.2% and 17.1% of male and female workers reported low work sustainability. Workers in the electronics industries and female workers in the healthcare and education sectors reported low work sustainability. Gender-specific analyses showed that low job control among men and shift work among women were significantly associated with low work sustainability. Age-specific analyses indicated that having poor health, shift work, and long working hours in younger workers, and having low job control in older workers were associated with low work sustainability.
    Conclusion: To retain older workers in the labor market, policies should aim at the improvement of psychosocial work conditions, and gender- and age-specific issues should be taken into consideration.
    MeSH term(s) Adult ; Humans ; Male ; Female ; Aged ; Taiwan/epidemiology ; Surveys and Questionnaires ; Retirement ; Social Status ; Age Factors ; Workplace/psychology
    Language English
    Publishing date 2023-10-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0293282
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  3. Article ; Online: Endotypic traits of supine position and supine-predominant obstructive sleep apnoea in Asian patients.

    Cheng, Wan-Ju / Finnsson, Eysteinn / Ágústsson, Jón S / Sands, Scott A / Hang, Liang-Wen

    The European respiratory journal

    2024  Volume 63, Issue 3

    Abstract: Background: Over half of all cases of obstructive sleep apnoea (OSA) are classified as supine-related OSA; however, the pathological endotype during supine position is not fully understood. This study aims to investigate the endotypic traits of supine- ... ...

    Abstract Background: Over half of all cases of obstructive sleep apnoea (OSA) are classified as supine-related OSA; however, the pathological endotype during supine position is not fully understood. This study aims to investigate the endotypic traits of supine-predominant OSA and explore the variations in endotypic traits between the supine and lateral positions.
    Methods: We prospectively recruited 689 adult patients with OSA from a single sleep centre between April 2020 and December 2022. Endotypic traits, namely arousal threshold, collapsibility, loop gain and upper airway muscle compensation, were retrieved from polysomnographic signals. We identified spOSA by a supine to non-supine apnoea-hypopnoea index (AHI) ratio >2. We cross-sectionally compared demographic and endotypic traits between supine-predominant OSA and non-positional OSA and examined the associations between supine-predominant OSA and endotypic traits. Additionally, we compared the changes in endotypic traits between supine and lateral positions in patients with supine-predominant OSA and non-positional OSA.
    Results: In our study sample, 75.8% of patients were identified as having supine-predominant OSA. Compared to non-positional OSA, supine-predominant OSA was associated with low collapsibility (β= -3.46 %
    Conclusions: Supine-predominant OSA is the prevalent phenotype of OSA in Asian patients. Inadequate upper airway compensation appears to be a crucial underlying pathology in patients with supine-predominant OSA.
    MeSH term(s) Adult ; Humans ; Supine Position/physiology ; Polysomnography ; Sleep Apnea, Obstructive/diagnosis ; Sleep
    Language English
    Publishing date 2024-03-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.01660-2023
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  4. Article ; Online: Associations of road traffic noise and its frequency spectrum with prevalent depression in Taichung, Taiwan.

    Lin, Jia-Yi / Cheng, Wan-Ju / Wu, Chang-Fu / Chang, Ta-Yuan

    Frontiers in public health

    2023  Volume 11, Page(s) 1116345

    Abstract: Introduction: Exposure to road traffic noise has been reported to be associated with depression in many epidemiological studies, but the association between noise frequency spectrum and depression remains unclear. This community-based study investigated ...

    Abstract Introduction: Exposure to road traffic noise has been reported to be associated with depression in many epidemiological studies, but the association between noise frequency spectrum and depression remains unclear. This community-based study investigated the associations between road traffic noise exposure and its frequency components with prevalent depression.
    Methods: A total of 3,191 residents living in Taichung who participated in the Taiwan Biobank between 2010 and 2017, were included as study participants. The land-use regression models were used to evaluate individual annual average values of A-weighted equivalent sound level over 24 h (L
    Results: An interquartile range increase in L
    Conclusion: Exposure to road traffic noise may be associated with an increased prevalence of depression, particularly at 1,000 and 2,000 Hz.
    MeSH term(s) Humans ; Noise, Transportation/adverse effects ; Depression/epidemiology ; Taiwan/epidemiology ; Particulate Matter/analysis ; Geographic Information Systems
    Chemical Substances Particulate Matter
    Language English
    Publishing date 2023-01-27
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1116345
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  5. Article ; Online: Association Between Retirement Age and Incidence of Depressive Disorders: A 19-Year Population-Based Study.

    Yang, Hang-Ju / Cheng, Yawen / Yu, Teng-Shun / Cheng, Wan-Ju

    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    2023  Volume 32, Issue 2, Page(s) 166–177

    Abstract: Objective: To investigate the occurrence of depressive disorders spanning the transition to retirement, and explore the relationship between retirement age and depressive disorders.: Methods: We utilized a national population-based health insurance ... ...

    Abstract Objective: To investigate the occurrence of depressive disorders spanning the transition to retirement, and explore the relationship between retirement age and depressive disorders.
    Methods: We utilized a national population-based health insurance database encompassing 2 million Taiwanese individuals from 2000 to 2019. The study focused on individuals aged 50 years and older who were employed at the baseline, and 84,224 individuals had records of retirement during the follow-up period. Depressive disorders were identified using codes from the International Classification of Diseases. To assess the trend in the incidence of depressive disorders 7-year period before and after retirement, an interrupted time series analysis was performed. Cox-proportional hazard models were employed to investigate the association between retirement age and the occurrence of depressive disorders following retirement.
    Results: The incidence of depression peaks at the time of retirement and shows a significant decrease after retirement. Incidence of depressive disorders was 6.4 and 7.6 per 1000 person-years among individuals who retired between the ages of 60-64 and 65-69. Comparing the two groups, those who retired between 65 and 69 exhibits a higher risk of developing depressive disorders (hazard ratio = 1.10, 95% confidence interval = 1.02-1.18). This association is particularly pronounced among women and individuals residing in areas with low urbanization levels.
    Conclusion: Retirement marks a crucial life milestone accompanied by a peak in depressive disorders. It is important to address the higher risk of depression associated with late retirement among socially disadvantaged groups.
    MeSH term(s) Humans ; Female ; Middle Aged ; Aged ; Retirement ; Incidence ; Proportional Hazards Models ; Depression/epidemiology ; Depressive Disorder/epidemiology ; Longitudinal Studies
    Language English
    Publishing date 2023-09-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1278145-9
    ISSN 1545-7214 ; 1064-7481
    ISSN (online) 1545-7214
    ISSN 1064-7481
    DOI 10.1016/j.jagp.2023.09.010
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  6. Article ; Online: Reply to letter by Dr. Fu and Dr. Chu: Risk factors for poor COVID-19 outcomes in patients with psychiatric disorders.

    Cheng, Wan-Ju / Shih, Hong-Mo / Su, Kuan-Pin / Hsueh, Po-Ren

    Brain, behavior, and immunity

    2023  Volume 115, Page(s) 448–449

    MeSH term(s) Humans ; COVID-19 ; Risk Factors ; Mental Disorders/complications
    Language English
    Publishing date 2023-11-04
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 639219-2
    ISSN 1090-2139 ; 0889-1591
    ISSN (online) 1090-2139
    ISSN 0889-1591
    DOI 10.1016/j.bbi.2023.10.029
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  7. Article ; Online: Risk factors for poor COVID-19 outcomes in patients with psychiatric disorders.

    Cheng, Wan-Ju / Shih, Hong-Mo / Su, Kuan-Pin / Hsueh, Po-Ren

    Brain, behavior, and immunity

    2023  Volume 114, Page(s) 255–261

    Abstract: Background: Coronavirus disease 2019 (COVID-19) has been found to have a greater impact on individuals with pre-existing psychiatric disorders. However, the underlying reasons for this increased risk have yet to be determined. This study aims to ... ...

    Abstract Background: Coronavirus disease 2019 (COVID-19) has been found to have a greater impact on individuals with pre-existing psychiatric disorders. However, the underlying reasons for this increased risk have yet to be determined. This study aims to investigate the potential factors contributing poor outcomes among COVID-19 patients with psychiatric disorders, including delayed diagnosis of infection, vaccination rates, immune response, and the use of psychotropic medications.
    Methods: This retrospective cohort study analyzed medical records of 15,783 adult patients who were diagnosed with COVID-19 infection by positive PCR tests between January and September 2022 at a single medical center. We identified psychiatric diagnoses using ICD-9 diagnostic codes from the preceding 3 years before COVID infection. Primary outcome was in-hospital mortality and secondary outcomes were severe illness requiring intensive care or mechanical ventilation, and hospitalization within 45 days after a positive COVID-19 test. We compared the rates of outcomes, viral load, vaccination status at the time of positive test, psychotropic medications prescription within 90 days prior, antiviral medication use, and blood inflammation markers between patients with and without psychiatric disorders. The Cox proportional hazard model was used to examine the association of psychiatric diagnoses, vaccination status, and psychotropic medication prescription with poor outcomes.
    Results: Patients with psychiatric disorders demonstrated higher rates of severe illness (10.4% v.s. 7.1%) and hospitalization (16.4% vs. 11.3%), as well as a shorter duration to in-hospital mortality (6 vs. 12.5 days) compared to non-psychiatric patients. Psychiatric patients had higher vaccination rates and lower levels of inflammatory markers than non-psychiatric patients. Antipsychotic medication use was associated with in-hospital mortality (hazard ratio [HR] = 4.79, 95% confidence interval [CI] = 1.23-18.7), while being unvaccinated was associated with hospitalization (HR = 1.81, 95% CI = 1.29 to 2.54) and severe illness (HR = 3.23, 95% CI = 1.95 to 5.34) among patients with psychiatric disorders. Sedatives prescription was associated with all poor outcomes in general patients.
    Conclusion: Considering the narrow time window between a positive COVID-19 test and poor outcomes, healthcare providers should undertake close monitoring of patients with preexisting psychiatric disorders during the initial days after a positive PCR test. Furthermore, caution should be taken when prescribing psychotropic medications, with special attention to antipsychotics.
    MeSH term(s) Adult ; Humans ; COVID-19 ; Retrospective Studies ; Mental Disorders/complications ; Mental Disorders/epidemiology ; Mental Disorders/diagnosis ; Antipsychotic Agents/therapeutic use ; Risk Factors
    Chemical Substances Antipsychotic Agents
    Language English
    Publishing date 2023-08-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 639219-2
    ISSN 1090-2139 ; 0889-1591
    ISSN (online) 1090-2139
    ISSN 0889-1591
    DOI 10.1016/j.bbi.2023.08.024
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  8. Article ; Online: Direction and magnitude of social jetlag are associated with obesity: Results from a sample of hospital employees.

    Li, Tin-May / Pien, Li-Chung / Cheng, Wan-Ju

    Chronobiology international

    2022  Volume 39, Issue 9, Page(s) 1242–1248

    Abstract: Social jetlag, the discrepancy between social and biological timing, has been suggested to disturb metabolic functions. However, the relationship between social jetlag and obesity has been inconsistent in other studies. In this study we examined the ... ...

    Abstract Social jetlag, the discrepancy between social and biological timing, has been suggested to disturb metabolic functions. However, the relationship between social jetlag and obesity has been inconsistent in other studies. In this study we examined the association between social jetlag and obesity among day and shift workers. We invited 2508 day workers and 1383 shift workers from a hospital worker health cohort to participate in a 2018-2019 survey on their sleep behaviors. Shift-specific social jetlag was quantified using the Munich ChronoType Questionnaire, and body mass index was measured during annual physical examinations. The distributions of shift-specific social jetlag were illustrated, and logistic regression analysis was used to examine the association between social jetlag and obesity. We found that high level of social jetlag (odds ratio [OR] = 1.26, 95% confidence interval [CI] = 1.08-1.47) and positive social jetlag (OR = 2.25, 95% CI = 1.30-3.90) during evening shifts were associated with obesity after adjustment for age, sex, health behaviors, and sleep quality. During night shift periods, sleep time varied greatly on free days, but the participants slept at similar times, namely 16:00, on workdays. In conclusion, phase advance on workdays and high levels of social jetlag were associated with obesity. Sleep timing should therefore be recommended according to the relative phase of individuals' preferred sleep time and work time.
    MeSH term(s) Circadian Rhythm ; Hospitals ; Humans ; Jet Lag Syndrome ; Obesity ; Sleep ; Surveys and Questionnaires
    Language English
    Publishing date 2022-07-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 998996-1
    ISSN 1525-6073 ; 0742-0528
    ISSN (online) 1525-6073
    ISSN 0742-0528
    DOI 10.1080/07420528.2022.2090953
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  9. Article ; Online: Relationship between Symptom Profiles and Endotypes among Patients with Obstructive Sleep Apnea: A Latent Class Analysis.

    Cheng, Wan-Ju / Finnsson, Eysteinn / Arnardóttir, Eydís / Ágústsson, Jón S / Sands, Scott A / Hang, Liang-Wen

    Annals of the American Thoracic Society

    2023  Volume 20, Issue 9, Page(s) 1337–1344

    Abstract: Rationale: ...

    Abstract Rationale:
    MeSH term(s) Humans ; Latent Class Analysis ; Polysomnography ; Sleep Apnea, Obstructive ; Sleep ; Cluster Analysis
    Language English
    Publishing date 2023-06-14
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202212-1054OC
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  10. Article ; Online: Continuous positive airway pressure and adherence in patients with different endotypes of obstructive sleep apnea.

    Cheng, Wan-Ju / Finnsson, Eysteinn / Ágústsson, Jón S / Sands, Scott A / Hang, Liang-Wen

    Journal of sleep research

    2023  Volume 33, Issue 1, Page(s) e13999

    Abstract: Determining the endotypes of obstructive sleep apnea (OSA) has potential implications for precision interventions. Here we assessed whether continuous positive airway pressure (CPAP) treatment outcomes differ across endotypic subgroups. We conducted a ... ...

    Abstract Determining the endotypes of obstructive sleep apnea (OSA) has potential implications for precision interventions. Here we assessed whether continuous positive airway pressure (CPAP) treatment outcomes differ across endotypic subgroups. We conducted a retrospective analysis of data obtained from 225 patients with moderate-to-severe OSA from a single sleep centre. Polysomnographic and CPAP titration study data were collected between May 2020 and January 2022. One-month CPAP treatment adherence was followed. Obstructive sleep apnea endotypes, namely arousal threshold, collapsibility, loop gain, and upper airway gain were estimated from polysomnography and dichotomised as high versus low. We examined associations between endotypic subgroups and (1) optimal CPAP titration pressure, (2) CPAP-related improvements in sleep architecture (proportions of slow-wave and rapid eye movement (REM) sleep), and (3) CPAP adherence. We observed that patients with high collapsibility required a higher CPAP pressure than those with low collapsibility (∆ = 0.4 cmH
    MeSH term(s) Humans ; Continuous Positive Airway Pressure ; Retrospective Studies ; Sleep Apnea, Obstructive/therapy ; Sleep ; Polysomnography
    Language English
    Publishing date 2023-07-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1122722-9
    ISSN 1365-2869 ; 0962-1105
    ISSN (online) 1365-2869
    ISSN 0962-1105
    DOI 10.1111/jsr.13999
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