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Article: Characteristics of intestinal flora in patients with cerebral infarction complicated with Type 2 diabetes mellitus.

Cheng, Xueying / Zhang, Zhengqian / Dong, Wen / Lun, Yongzhi / Liu, Ben

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences

2024 Volume 48, Issue 8, Page(s) 1163–1175

Abstract: Objectives: The intestinal microbial characteristics of patients with simple cerebral infarction (CI) and CI complicated with Type 2 diabetes mellitus (CI-T2DM) are still not clear. This study aims to analyze the differences in the variable ... ...

Title translation	脑梗死合并2型糖尿病患者的肠道菌群特征(英文).
Abstract	Objectives: The intestinal microbial characteristics of patients with simple cerebral infarction (CI) and CI complicated with Type 2 diabetes mellitus (CI-T2DM) are still not clear. This study aims to analyze the differences in the variable characteristics of intestinal flora between patients simply with CI and CI-T2DM. Methods: This study retrospectively collected the patients who were admitted to the Affiliated Hospital of Putian University from September 2021 to September 2022. The patients were divided into a CI group ( Results: At phylum level, the average ratio of Firmicutes, Bacteroidetes, and Proteobacteria in the CI-T2DM group were 33.07%, 54.80%, and 7.00%, respectively. In the CI group, the ratios of each were 14.03%, 69.62%, and 11.13%, respectively, while in the control group, the ratios were 50.99%, 37.67%, and 5.24%, respectively. There was significant differences in the distribution of Firmicutes ( Conclusions: From phylum level to species level, the composition of intestinal flora in the patients with CI-T2DM is different from those in the patients simply with CI. The change in the proportion of
MeSH term(s)	Humans ; Gastrointestinal Microbiome/genetics ; Diabetes Mellitus, Type 2/complications ; Retrospective Studies ; Bacteria/genetics ; High-Throughput Nucleotide Sequencing
Language	Chinese
Publishing date	2024-03-19
Publishing country	China
Document type	Journal Article
ZDB-ID	2168533-2
ISSN	1672-7347
ISSN	1672-7347
DOI	10.11817/j.issn.1672-7347.2023.220558
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Article ; Online: Clinical Features and Risk Factors of Kawasaki Disease Complicated with Deep Neck Space Involvement

ZHU Xiaona / CHENG Xueying / WENG Ruohang / XIA Yu / LUO Ying / HE Tingyan / YANG Jun

Xiehe Yixue Zazhi, Vol 14, Iss 2, Pp 285-

A Summary of 38 Cases

2023 Volume 291

Abstract: Objective To summarize the clinical characteristics and explore the risk factors of Kawasaki disease(KD) with deep neck space involvement(DNSI). Methods This study was a case-control study. We reviewed KD complicated with DNSI patients in Department of ... ...

Abstract	Objective To summarize the clinical characteristics and explore the risk factors of Kawasaki disease(KD) with deep neck space involvement(DNSI). Methods This study was a case-control study. We reviewed KD complicated with DNSI patients in Department of Rheumatology and Immunology of Shenzhen Children's Hospital from January 2018 to December 2020 as DNSI group. Meanwhile, children with KD withoutDNSI during this period were selected by systematic sampling at a ratio of 1∶7 as control group. The clinical characteristics were analyzed by Chi-square test and the Mann-Whitney test and risk factors of KD complicated with DNSI were analyzed by Logistic regression. Results A total of 38 children in the DNSI group who met the inclusion and exclusion criteria and 288 children in the control group were selected. In the DNSI group, 38 children (100%) had fever and cervical lymph node enlargement, and the cervical lymph node enlargement occurred within 5 days of onset; 30 patients (78.9%) had cervical lymph node pain and 25 patients suffered (65.8%) limited movement of neck. Compared with the control group, the clinical data of children in the DNSI group showed a variety of significant changes. In terms of clinical characteristics, the age of onset in the DNSI group was older, the hospital stay was longer and the proportions of cervical lymphadenopathy, cervical lymph node pain, limited neck movement and upper airway obstruction were all higher (all P < 0.05); in terms of laboratory tests, the neutrophil count and its percentage, C-reactive protein (CRP), ferritin (FER), total bile acid, total bilirubin, direct bilirubin, and globulin levels all increased, while platelet and lymphocyte counts and their percentages all decreased(all P < 0.05); in terms of coronary artery damage and treatment effect, the Kobayashi score, Sano score and the proportion of hormone therapy in the DNSI group all increased (all P < 0.05). Multivariate Logistic regression analysis showed that neck lymph node pain (OR=5.523, 95% CI: ...
Keywords	kawasaki disease ; deep neck space involvement ; inflammatory disease ; limited cervical movement ; Medicine ; R
Subject code	610
Language	Chinese
Publishing date	2023-03-01T00:00:00Z
Publisher	Editorial Office of Medical Journal of Peking Union Medical College Hospital
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Cloud top height retrieval over the Arctic Ocean using a cloud-shadow method based on MODIS

Cheng, Xueying / Yi, Li / Bendix, Jörg

Atmospheric research. 2021 May, v. 253

2021

Abstract: Cloud top height (CTH) plays an important role in the Earth's radiation budget and thus in climate change. However, accurate CTH retrieval based on satellite data remains a challenge when using currently widespread methods based on passive remote sensing ...

Abstract	Cloud top height (CTH) plays an important role in the Earth's radiation budget and thus in climate change. However, accurate CTH retrieval based on satellite data remains a challenge when using currently widespread methods based on passive remote sensing satellite data, particularly over the Arctic Ocean. It is well known that using geometric correlation between CTH and cloud-shadow distance along the normal direction of sunlight, cloud-edge top height (CETH) can be determined. However, this cloud-shadow method (CSM) exhibited larger CTH errors due to low-resolution weather satellite data of the past. The aim of the paper is to analyze the effect of higher-resolution images (MODIS with 250-m resolution) on CSM accuracy. We present a method in which CETH is first retrieved using the MODIS data, and to calculate CTH in the center of cloud region by combining the calculated CETH and cloud top brightness temperature using an environmental temperature lapse rate method. We validated 14 cases over the Arctic Ocean by the CALIPSO (Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations) CTH lidar product and another two cases by radiosonde data. CSM revealed better performance (mean difference is 0.45 km and standard deviation is 0.92 km) compared to the operational MODIS CTH product (mean difference is −0.78 km and standard deviation is 1.78 km), when validated by the CALIPSO product. When validated by sounding data, CSM also performed better than the MODIS CTH product: the CSM CTH errors are 0.41 and 0.52 km in two sounding cases, while the corresponding MODIS CTH errors are −1.10 and 1.07 km. The CSM technique especially showed better performance for double-deck cloud systems. We conclude that further improvements in CTH accuracy based on CSM can be achieved by mainly using higher-resolution satellite imagery.
Keywords	ambient temperature ; climate change ; geometry ; lidar ; remote sensing ; research ; satellites ; solar radiation ; standard deviation ; Arctic Ocean
Language	English
Dates of publication	2021-05
Publishing place	Elsevier B.V.
Document type	Article
Note	NAL-AP-2-clean
ISSN	0169-8095
DOI	10.1016/j.atmosres.2021.105468
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Analysis on the physiological changes of residents before and during the COVID-19 pandemic: A cross-sectional study.

Chen, Jinlong / Cheng, Xueying / Xu, Yue / Shi, Tingting / Zhu, Chunran / Wang, Xu

Journal of medical virology

2023 Volume 95, Issue 2, Page(s) e28562

Abstract: People's lifestyles have changed dramatically during the coronavirus disease 2019 (COVID-19) pandemic, yet data on physical examinations in the Chinese population before and during the pandemic are rarely reported. The study was based on the data from ... ...

Abstract	People's lifestyles have changed dramatically during the coronavirus disease 2019 (COVID-19) pandemic, yet data on physical examinations in the Chinese population before and during the pandemic are rarely reported. The study was based on the data from the physical examination center of Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine. We collected the data of physical examinations information between January 2017 and March 2022. The data of participants before December 31, 2019 were classified as "before COVID-19 pandemic group," while data after December 31, 2019 were classified as "during COVID-19 pandemic group." We used t-test and χ
MeSH term(s)	Humans ; COVID-19 ; Pandemics ; Cross-Sectional Studies ; SARS-CoV-2 ; Life Style
Language	English
Publishing date	2023-02-08
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	752392-0
ISSN	1096-9071 ; 0146-6615
ISSN (online)	1096-9071
ISSN	0146-6615
DOI	10.1002/jmv.28562
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Article: [The Study of PI3K-Ⅲ Like Functional Polypeptide on Leukemia Cell K562 during the Process of Programmed Cell Death].

Liu, Ben / Dong, Wen / Sun, Jie / Pan, Ling-Hong / Cheng, Xue-Ying / Lun, Yong-Zhi

Zhongguo shi yan xue ye xue za zhi

2022 Volume 30, Issue 4, Page(s) 990–997

Abstract: Objective: To study the molecular mechanism of PI3K-Ⅲ like functional domain inducing programmed cell death of leukemia cell line K562.: Methods: The purified PI3K-Ⅲ like functional domain protein was obtained by Pichia pastoris expression system. ... ...

Abstract	Objective: To study the molecular mechanism of PI3K-Ⅲ like functional domain inducing programmed cell death of leukemia cell line K562. Methods: The purified PI3K-Ⅲ like functional domain protein was obtained by Pichia pastoris expression system. MTT assay and colony-forming assay were used to detect the effects of PI3K-Ⅲ like functional domain protein on K562 cell proliferation. The effects of PI3K-Ⅲ like functional domain protein on apoptosis and cell cycle of on K562 cells were detected by flow cytometry. The ultrastructural changes were detected by transmission electron microscopy. The expression of caspase-3 was detected by ELISA. The protein expressions of ATG4B, Beclin-1, Bcl-2 and LC3-II were evaluated by Western blot. Results: PI3K-Ⅲ like functional domain protein could inhibit the proliferation and clony formation of K562 cells, which was significantly higher than the control group (P<0.05). In the experimental group, apoptosis and autophagosome were shown in K562 cells. The proportion of cells in G Conclusion: PI3K-Ⅲ like functional polypeptide could induce programmed cell death of leukemia cell K562. Beclin-1/Bcl-2 and caspase pathway may be involved in this way, which suggesting meant autophagy and apoptosis may work together at the same time.
MeSH term(s)	Apoptosis ; Beclin-1/pharmacology ; Caspase 3/metabolism ; Cell Proliferation ; Humans ; K562 Cells ; Leukemia ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism
Chemical Substances	Beclin-1 ; Proto-Oncogene Proteins c-bcl-2 ; Caspase 3 (EC 3.4.22.-)
Language	Chinese
Publishing date	2022-08-18
Publishing country	China
Document type	Journal Article
ZDB-ID	2404306-0
ISSN	1009-2137
ISSN	1009-2137
DOI	10.19746/j.cnki.issn.1009-2137.2022.04.003
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Article ; Online: Lysophosphatidic acid contributes to myocardial ischemia/reperfusion injury by activating TRPV1 in spinal cord.

Wu, Chao / Sun, Meiyan / Qile, Muge / Zhang, Yu / Liu, Liu / Cheng, Xueying / Dai, Xiaoxiao / Gross, Eric R / Zhang, Ye / He, Shufang

Basic research in cardiology

2024 Volume 119, Issue 2, Page(s) 329–348

Abstract: Lysophosphatidic acid (LPA) is a bioactive phospholipid that plays a crucial role in cardiovascular diseases. Here, we question whether LPA contributes to myocardial ischemia/reperfusion (I/R) injury by acting on transient receptor potential vanilloid 1 ( ...

Abstract	Lysophosphatidic acid (LPA) is a bioactive phospholipid that plays a crucial role in cardiovascular diseases. Here, we question whether LPA contributes to myocardial ischemia/reperfusion (I/R) injury by acting on transient receptor potential vanilloid 1 (TRPV1) in spinal cord. By ligating the left coronary artery to establish an in vivo I/R mouse model, we observed a 1.57-fold increase in LPA level in the cerebrospinal fluid (CSF). The I/R-elevated CSF LPA levels were reduced by HA130, an LPA synthesis inhibitor, compared to vehicle treatment (4.74 ± 0.34 vs. 6.46 ± 0.94 μg/mL, p = 0.0014). Myocardial infarct size was reduced by HA130 treatment compared to the vehicle group (26 ± 8% vs. 46 ± 8%, p = 0.0001). To block the interaction of LPA with TRPV1 at the K710 site, we generated a K710N knock-in mouse model. The TRPV1
MeSH term(s)	Mice ; Animals ; Myocardial Reperfusion Injury/prevention & control ; TRPV Cation Channels/genetics ; Peptides/metabolism ; Spinal Cord/metabolism ; Lysophospholipids
Chemical Substances	lysophosphatidic acid (PG6M3969SG) ; TRPV Cation Channels ; Peptides ; TRPV1 protein, mouse ; Lysophospholipids
Language	English
Publishing date	2024-01-18
Publishing country	Germany
Document type	Journal Article
ZDB-ID	189755-x
ISSN	1435-1803 ; 0300-8428 ; 0175-9418
ISSN (online)	1435-1803
ISSN	0300-8428 ; 0175-9418
DOI	10.1007/s00395-023-01031-z
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Article ; Online: Synergetic effect of hydrochar on the transport of anatase titanium dioxide nanoparticles in the presence of phosphate in saturated quartz sand.

Cheng, Xueying / Xu, Nan / Huangfu, Xinxing / Zhou, Xing / Zhang, Mo

Environmental science and pollution research international

2018 Volume 25, Issue 29, Page(s) 28864–28874

Abstract: The rapid development of nanomaterials has led to the unavoidable leakage and release of nanoparticles (NPs) into soil and the underlying groundwater. It is possible for chars and phosphate introduced into soil to improve crop soil properties by ... ...

Abstract	The rapid development of nanomaterials has led to the unavoidable leakage and release of nanoparticles (NPs) into soil and the underlying groundwater. It is possible for chars and phosphate introduced into soil to improve crop soil properties by improving contact with NPs. In this study, the influences of hydrochar and/or phosphate on the anatase nTiO
MeSH term(s)	Adsorption ; Charcoal/chemistry ; Environmental Pollution ; Environmental Restoration and Remediation/methods ; Groundwater/chemistry ; Nanoparticles/chemistry ; Phosphates/chemistry ; Quartz ; Silicon Dioxide ; Soil/chemistry ; Titanium/chemistry
Chemical Substances	Phosphates ; Soil ; Quartz (14808-60-7) ; titanium dioxide (15FIX9V2JP) ; Charcoal (16291-96-6) ; Silicon Dioxide (7631-86-9) ; Titanium (D1JT611TNE)
Language	English
Publishing date	2018-08-11
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-018-2795-3
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Article: Case Report: Rare Iliac Vein Compression (May-Thurner) Syndrome in a Pediatric Patient.

Ji, Lianfu / Yang, Fan / Chen, Xuan / Chen, Jinlong / Cheng, Xueying / Yin, Jie / Qin, Yuming / Yang, Shiwei

Frontiers in pediatrics

2021 Volume 9, Page(s) 694782

Abstract: Iliac vein compression syndrome (IVCS) or May-Thurner syndrome occurs predominantly in young to middle-aged women. Here we reported a case of IVCS in a 5-year-old boy. The child was admitted to our vasculocardiology department with left lower extremity ... ...

Abstract	Iliac vein compression syndrome (IVCS) or May-Thurner syndrome occurs predominantly in young to middle-aged women. Here we reported a case of IVCS in a 5-year-old boy. The child was admitted to our vasculocardiology department with left lower extremity that had been swollen for 1 month. Blood tests revealed coagulation routine and platelets in the normal ranges. Computer tomography angiography (CTA) and magnetic resonance imaging (MRI) showed the left common iliac vein had become narrow before it entered the right common iliac vein. To further clarify, we performed angiography, which clearly showed the stenosis and the blood return of the left common iliac vein. So IVCS was diagnosed. What is more, we found the aorta descended to the right of the spine, and this may be the reason for the apparent compression of the left common iliac vein. Given the young age and mild symptoms of the child, the treatment was conservative mainly including elevation of the affected limb, wearing medical elastic socks, and short-term oral aspirin for anticoagulation. Meanwhile, the boy is being followed up closely. If the swelling of the left lower extremity significantly increases, stent placement may need to be considered in the future.
Language	English
Publishing date	2021-07-15
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2711999-3
ISSN	2296-2360
ISSN	2296-2360
DOI	10.3389/fped.2021.694782
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Article: Synergetic effect of hydrochar on the transport of anatase titanium dioxide nanoparticles in the presence of phosphate in saturated quartz sand

Cheng, Xueying / Xu, Nan / Huangfu, Xinxing / Zhou, Xing / Zhang, Mo

Environmental science and pollution research international. 2018 Oct., v. 25, no. 29

2018

Abstract	The rapid development of nanomaterials has led to the unavoidable leakage and release of nanoparticles (NPs) into soil and the underlying groundwater. It is possible for chars and phosphate introduced into soil to improve crop soil properties by improving contact with NPs. In this study, the influences of hydrochar and/or phosphate on the anatase nTiO2 transport behaviors were investigated under different conditions. The breakthrough curves (BTCs) and retention profiles were obtained by the saturated sand column experiments. The additional analysis of zeta potentials, sedimentation kinetics, Raman mapping, and the two-site kinetic attachment model (TSKAM) was conducted to explore the possible underlying mechanisms. The simultaneous presence of phosphate and hydrochar acted in a synergetic fashion to enhance the transport of nTiO2 in a sand medium compared to the facilitated effect of single phosphate or hydrochar. The higher levels of hydrochar induce the more nTiO2 in the high IC solution passing through the saturated sand columns in the co-presence of phosphate. It was attributed to the competitive adsorption of hydrochar with nTiO2 to the sand site and the phosphate adsorption on nTiO2 occurred simultaneously through the sand columns. The fitting results of BTCs using TSKAM showed that the value of k2 for nTiO2 (the irreversible attachment coefficient at site 2) was smaller than that of k1d/k1 (the first-order reversible detachment and attachment coefficient at site 1, respectively), suggesting irreversible retention of anatase nTiO2 at site 1. The value of k1d/k1 could be better used to explain the retention of nTiO2 with combined phosphate and hydrochar. This study provides insight into the implications of phosphate and/or hydrochar for nTiO2 transport in crop soil environments. Graphical abstract ᅟ
Keywords	Raman spectroscopy ; adsorption ; groundwater ; hydrochars ; models ; nanoparticles ; phosphates ; quartz ; sand ; soil properties ; synergism ; titanium dioxide ; zeta potential
Language	English
Dates of publication	2018-10
Size	p. 28864-28874.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-018-2795-3
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Article ; Online: Facilitated transport of nTiO

Xu, Nan / Li, Zuling / Huangfu, Xinxing / Cheng, Xueying / Christodoulatos, Christos / Qian, Junchao / Chen, Ming / Chen, Jianping / Su, Chunming / Wang, Dengjun

The Science of the total environment

2020 Volume 713, Page(s) 136589

Abstract: The soil major component of clay plays an important role in governing the fate and transport of engineered nanomaterials (e.g., the most commonly used titanium dioxide nanoparticles; ... ...

Abstract	The soil major component of clay plays an important role in governing the fate and transport of engineered nanomaterials (e.g., the most commonly used titanium dioxide nanoparticles; nTiO
MeSH term(s)	Escherichia coli ; Kaolin ; Nanoparticles ; Phosphates ; Quartz ; Sand ; Silicon Dioxide ; Titanium ; Water
Chemical Substances	Phosphates ; Sand ; Water (059QF0KO0R) ; Quartz (14808-60-7) ; Kaolin (24H4NWX5CO) ; Silicon Dioxide (7631-86-9) ; Titanium (D1JT611TNE)
Language	English
Publishing date	2020-01-11
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2020.136589
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