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  1. Article ; Online: The Implementation of a Gesture Recognition System with a Millimeter Wave and Thermal Imager.

    Cheng, Yi-Lin / Yeh, Wen-Hsiang / Liao, Yu-Ping

    Sensors (Basel, Switzerland)

    2024  Volume 24, Issue 2

    Abstract: During the COVID-19 pandemic, the number of cases continued to rise. As a result, there was a growing demand for alternative control methods to traditional buttons or touch screens. However, most current gesture recognition technologies rely on machine ... ...

    Abstract During the COVID-19 pandemic, the number of cases continued to rise. As a result, there was a growing demand for alternative control methods to traditional buttons or touch screens. However, most current gesture recognition technologies rely on machine vision methods. However, this method can lead to suboptimal recognition results, especially in situations where the camera is operating in low-light conditions or encounters complex backgrounds. This study introduces an innovative gesture recognition system for large movements that uses a combination of millimeter wave radar and a thermal imager, where the multi-color conversion algorithm is used to improve palm recognition on the thermal imager together with deep learning approaches to improve its accuracy. While the user performs gestures, the mmWave radar captures point cloud information, which is then analyzed through neural network model inference. It also integrates thermal imaging and palm recognition to effectively track and monitor hand movements on the screen. The results suggest that this combined method significantly improves accuracy, reaching a rate of over 80%.
    MeSH term(s) Humans ; Gestures ; Pandemics ; Algorithms ; COVID-19/diagnosis ; Hand/diagnostic imaging
    Language English
    Publishing date 2024-01-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s24020581
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Interplay between group A

    Su, Marcia Shu-Wei / Cheng, Yi-Lin / Lin, Yee-Shin / Wu, Jiunn-Jong

    Microbiology and molecular biology reviews : MMBR

    2024  Volume 88, Issue 1, Page(s) e0005222

    Abstract: SUMMARYGroup ... ...

    Abstract SUMMARYGroup A
    MeSH term(s) Humans ; Streptococcus pyogenes ; Streptococcal Infections/pathology ; Immunity, Innate ; Virulence Factors ; Phagocytosis
    Chemical Substances Virulence Factors
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1376131-6
    ISSN 1098-5557 ; 1070-6275 ; 1092-2172
    ISSN (online) 1098-5557 ; 1070-6275
    ISSN 1092-2172
    DOI 10.1128/mmbr.00052-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Cryptanalysis and Improvement of a Chaotic Map-Based Image Encryption System Using Both Plaintext Related Permutation and Diffusion

    Cheng-Yi Lin / Ja-Ling Wu

    Entropy, Vol 22, Iss 589, p

    2020  Volume 589

    Abstract: In theory, high key and high plaintext sensitivities are a must for a cryptosystem to resist the chosen/known plaintext and the differential attacks. High plaintext sensitivity can be achieved by ensuring that each encrypted result is plaintext-dependent. ...

    Abstract In theory, high key and high plaintext sensitivities are a must for a cryptosystem to resist the chosen/known plaintext and the differential attacks. High plaintext sensitivity can be achieved by ensuring that each encrypted result is plaintext-dependent. In this work, we make detailed cryptanalysis on a published chaotic map-based image encryption system, where the encryption process is plaintext Image dependent. We show that some designing flaws make the published cryptosystem vulnerable to chosen-plaintext attack, and we then proposed an enhanced algorithm to overcome those flaws.
    Keywords image encryption ; chaotic map ; permutation ; diffusion ; cryptanalysis ; Science ; Q ; Astrophysics ; QB460-466 ; Physics ; QC1-999
    Language English
    Publishing date 2020-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Improved Mass-Transfer Enhances Photo-Driven Dye Degradation and H2 Evolution over a Few-Layer WS2/ZnO Heterostructure

    Yu-Ju Huang / Lian-Ming Lyu / Cheng-Yi Lin / Guan-Chi Lee / Kai-Yuan Hsiao / Ming-Yen Lu

    ACS Omega, Vol 7, Iss 2, Pp 2217-

    2022  Volume 2223

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Iatrogenic Kaposi sarcoma of the small bowel in Crohn’s disease following short-term use of immunomodulators

    Pei-Jui Wu / Chi-Shu Sun / Hsing-Tao Kuo / Ming-Jen Sheu / Cheng-Yi Lin / Su-Hung Wang / Chun-Chi Yang / Chi‐Hsing Chen / Shih-Sung Chuang / I-Che Feng

    Journal of Medical Case Reports, Vol 16, Iss 1, Pp 1-

    a case report and review of the literature

    2022  Volume 6

    Abstract: Abstract Background Kaposi sarcoma is a vascular tumor highly related to human herpesvirus-8 and Kaposi sarcoma–associated herpesvirus. Kaposi sarcoma usually manifests as skin or mucosal lesions; involvement in visceral organs such as the ... ...

    Abstract Abstract Background Kaposi sarcoma is a vascular tumor highly related to human herpesvirus-8 and Kaposi sarcoma–associated herpesvirus. Kaposi sarcoma usually manifests as skin or mucosal lesions; involvement in visceral organs such as the gastrointestinal tract is rare. Kaposi sarcoma can occur in immunocompromised patients receiving immunosuppressive therapy, in which case it is known as iatrogenic Kaposi sarcoma or drug-induced Kaposi sarcoma. Intestinal Kaposi sarcoma in patients with inflammatory bowel disease is extremely rare. Case presentation A 46-year-old East Asian male with recently diagnosed Crohn’s disease was administered azathioprine and prednisolone; however, the patient complained of persistent abdominal pain and diarrhea following treatment. Endoscopy revealed small bowel Kaposi sarcoma. The patient was treated with systemic chemotherapy successfully without relapse. Conclusions This is the fifth case of Kaposi sarcoma developed over the small intestine in a patient with Crohn’s disease following administration of immunomodulators. Additionally, this case indicated that even short-term immunomodulator use can induce Kaposi sarcoma in patients with inflammatory bowel disease. Thus, in patients with inflammatory bowel disease, if symptoms are aggravated or do not abate after immunomodulators prescription, and before intending to upgrade immunomodulators, endoscopy should be considered. Finally, chemotherapy can also be considered if both medication withdrawal and surgical intervention are not feasible.
    Keywords Crohn’s disease ; Chemotherapy ; Gastrointestinal Kaposi sarcoma ; Immunomodulator ; Kaposi sarcoma ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: The Relationship of Academic Collaborative Degree and Academic Productivity

    Chao-Chen Chen / Cheng-Yi Lin

    Journal of Library and Information Science Research, Vol 7, Iss 2, Pp 1-

    2013  Volume 28

    Abstract: Academic research plays an important role in universities and higher education evaluation. A correlation between a researcher’s scope of collaboration and his/her research impact. That’s why collaboration becomes more and more popular. When discussing ... ...

    Abstract Academic research plays an important role in universities and higher education evaluation. A correlation between a researcher’s scope of collaboration and his/her research impact. That’s why collaboration becomes more and more popular. When discussing about research collaborations, we found that most of the related literatures were based on subjects or a field. Relative few studies have been done in Taiwan to explore the relationship between collaboration and scholarly performance at the university level. Furthermore, analyzing research collaborations of a whole university provides invaluable inpust into the strategic planning of a university. Therefore, we represent collaboration in academic papers of Web of science (WoS) in the last two decades and analyze publication of National Taiwan Normal University by applying several bibliometric and SNA techniques.
    Keywords Academic co-authoring ; Academic productivity ; Collaborative Degree ; Social Network Analysis ; Bibliometrics ; Bibliography. Library science. Information resources ; Z ; DOAJ:Library and Information Science ; DOAJ:Social Sciences
    Subject code 001
    Language Chinese
    Publishing date 2013-06-01T00:00:00Z
    Publisher Library Association of the Republic of China (Taiwan)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Erratum for Cheng et al., "Group A

    Cheng, Yi-Lin / Kuo, Chih-Feng / Lu, Shiou-Ling / Omori, Hiroko / Wu, Ya-Na / Hsieh, Cheng-Lu / Noda, Takeshi / Wu, Shang-Rung / Anderson, Robert / Lin, Chiou-Feng / Chen, Chia-Ling / Wu, Jiunn-Jong / Lin, Yee-Shin

    mBio

    2021  Volume 12, Issue 4, Page(s) e0225021

    Language English
    Publishing date 2021-08-31
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 2557172-2
    ISSN 2150-7511 ; 2161-2129
    ISSN (online) 2150-7511
    ISSN 2161-2129
    DOI 10.1128/mBio.02250-21
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  8. Article ; Online: Combination Therapy with Low-Dose IVIG and a C1-esterase Inhibitor Ameliorates Brain Damage and Functional Deficits in Experimental Ischemic Stroke.

    Chen, Xinzhi / Arumugam, Thiruma V / Cheng, Yi-Lin / Lee, Jong-Hwan / Chigurupati, Srinivasulu / Mattson, Mark P / Basta, Milan

    Neuromolecular medicine

    2018  Volume 20, Issue 1, Page(s) 63–72

    Abstract: Acute ischemic stroke causes a high rate of deaths and permanent neurological deficits in survivors. Current interventional treatment, in the form of enzymatic thrombolysis, benefits only a small percentage of patients. Brain ischemia triggers ... ...

    Abstract Acute ischemic stroke causes a high rate of deaths and permanent neurological deficits in survivors. Current interventional treatment, in the form of enzymatic thrombolysis, benefits only a small percentage of patients. Brain ischemia triggers mobilization of innate immunity, specifically the complement system and Toll-like receptors (TLRs), ultimately leading to an exaggerated inflammatory response. Here we demonstrate that intravenous immunoglobulin (IVIG), a scavenger of potentially harmful complement fragments, and C1-esterase inhibitor (C1-INH), an inhibitor of complement activation, exert a beneficial effect on the outcome of experimental brain ischemia (I) and reperfusion (R) injury induced by transient occlusion of middle cerebral artery in mice. Both IVIG and C1-INH significantly and in a dose-responsive manner reduced brain infarction size, neurological deficit and mortality when administered to male mice 30 min before ischemia or up to 6 h after the onset of reperfusion. When combined, suboptimal doses of IVIG and C1-INH potentiated each other's neuroprotective therapeutic effects. Complement C3 and TLR2 signals were colocalized and significantly greater in brain cells adjacent to infracted brain lesions when compared to the corresponding regions of the contralateral hemisphere and to control (sham) mice. Treatment with IVIG and C1-INH effectively reduced deposition of C3b and downregulated excessive TLR2 and p-JNK1 expression at the site of I/R injury. Taken together, these results provide a rationale for potential use of IVIG and C1-INH, alone or in combination with ischemic stroke and other neurological conditions that involve inappropriately activated components of the innate immune system.
    MeSH term(s) Animals ; Brain/drug effects ; Brain/pathology ; Complement Activation/drug effects ; Complement C1 Inhibitor Protein/administration & dosage ; Complement C1 Inhibitor Protein/therapeutic use ; Complement C3b/analysis ; Complement Inactivating Agents/administration & dosage ; Complement Inactivating Agents/therapeutic use ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical ; Drug Therapy, Combination ; Female ; Gait Disorders, Neurologic/etiology ; Gait Disorders, Neurologic/prevention & control ; Immunoglobulins, Intravenous/administration & dosage ; Immunoglobulins, Intravenous/therapeutic use ; Infarction, Middle Cerebral Artery/complications ; Infarction, Middle Cerebral Artery/drug therapy ; Infarction, Middle Cerebral Artery/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mitogen-Activated Protein Kinase 8/metabolism ; Neuroprotective Agents/administration & dosage ; Neuroprotective Agents/therapeutic use ; Single-Blind Method ; Toll-Like Receptor 2/biosynthesis ; Toll-Like Receptor 2/genetics ; Up-Regulation
    Chemical Substances Complement C1 Inhibitor Protein ; Complement Inactivating Agents ; Immunoglobulins, Intravenous ; Neuroprotective Agents ; Tlr2 protein, mouse ; Toll-Like Receptor 2 ; Complement C3b (80295-43-8) ; Mitogen-Activated Protein Kinase 8 (EC 2.7.11.24)
    Language English
    Publishing date 2018-01-03
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2077809-0
    ISSN 1559-1174 ; 1535-1084
    ISSN (online) 1559-1174
    ISSN 1535-1084
    DOI 10.1007/s12017-017-8474-6
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    Zs.A 5818: Show issues Location:
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  9. Article ; Online: Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection.

    Shin, Donghyuk / Bhattacharya, Anshu / Cheng, Yi-Lin / Alonso, Marta Campos / Mehdipour, Ahmad Reza / van der Heden van Noort, Gerbrand J / Ovaa, Huib / Hummer, Gerhard / Dikic, Ivan

    eLife

    2020  Volume 9

    Abstract: Legionella ... ...

    Abstract Legionella pneumophila
    MeSH term(s) Bacteria/enzymology ; Cell Line ; Deubiquitinating Enzymes/genetics ; Deubiquitinating Enzymes/metabolism ; Escherichia coli ; Gene Expression Regulation, Bacterial/physiology ; Gene Expression Regulation, Enzymologic/physiology ; Humans ; Legionella ; Legionellosis ; Models, Molecular ; Protein Binding ; Protein Conformation ; Ubiquitination
    Chemical Substances Deubiquitinating Enzymes (EC 3.4.19.12)
    Language English
    Publishing date 2020-11-13
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.58277
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  10. Article ; Online: Emerging roles of the γ-secretase-notch axis in inflammation.

    Cheng, Yi-Lin / Choi, Yuri / Sobey, Christopher G / Arumugam, Thiruma V / Jo, Dong-Gyu

    Pharmacology & therapeutics

    2015  Volume 147, Page(s) 80–90

    Abstract: γ-Secretase is a distinct proteolytic complex required for the activation of many transmembrane proteins. The cleavage of substrates by γ-secretase plays diverse biological roles in producing essential products for the organism. More than 90 ... ...

    Abstract γ-Secretase is a distinct proteolytic complex required for the activation of many transmembrane proteins. The cleavage of substrates by γ-secretase plays diverse biological roles in producing essential products for the organism. More than 90 transmembrane proteins have been reported to be substrates of γ-secretase. Two of the most widely known and studied of these substrates are the amyloid precursor protein (APP) and the Notch receptor, which are precursors for the generation of amyloid-β (Aβ) and the Notch intracellular domain (NICD), respectively. The wide spectrum of γ-secretase substrates has made analyses of the pathology of γ-secretase-related diseases and underlying mechanisms challenging. Inflammation is an important aspect of disease pathology that requires an in-depth analysis. γ-Secretase may contribute to disease development or progression by directly increasing and regulating production of pro-inflammatory cytokines. This review summarizes recent evidence for a role of γ-secretase in inflammatory diseases, and discusses the potential use of γ-secretase inhibitors as an effective future treatment option.
    MeSH term(s) Alzheimer Disease/drug therapy ; Alzheimer Disease/metabolism ; Amyloid Precursor Protein Secretases/antagonists & inhibitors ; Amyloid Precursor Protein Secretases/physiology ; Animals ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/therapeutic use ; Humans ; Inflammation/drug therapy ; Inflammation/metabolism ; Receptors, Notch/antagonists & inhibitors ; Receptors, Notch/physiology ; Stroke/drug therapy ; Stroke/metabolism
    Chemical Substances Enzyme Inhibitors ; Receptors, Notch ; Amyloid Precursor Protein Secretases (EC 3.4.-)
    Language English
    Publishing date 2015-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 194735-7
    ISSN 1879-016X ; 0163-7258
    ISSN (online) 1879-016X
    ISSN 0163-7258
    DOI 10.1016/j.pharmthera.2014.11.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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