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  1. Article: Factors influencing smart device addiction among preschool children: An extended protection-risk model perspective.

    Cheng, Lu / Cao, Junwei

    Frontiers in psychology

    2023  Volume 14, Page(s) 1017772

    Abstract: Today, users of smart devices are from increasingly younger generations, and their use is very common among preschoolers. The problem of smart device addiction in preschool children has attracted widespread attention, due to which this study explores the ...

    Abstract Today, users of smart devices are from increasingly younger generations, and their use is very common among preschoolers. The problem of smart device addiction in preschool children has attracted widespread attention, due to which this study explores the influencing factors in children aged 2-5 years. Based on the protection-risk model, 236 Chinese parents were surveyed, and the data was analyzed using partial least squares structural equation modeling. The findings show that parental emotion regulation significantly and negatively influences children's depression and social withdrawal symptoms, whereas it has a significant and positive influence on parental self-control as well as outdoor intention. Also, children's depression and social withdrawal symptoms have a significant and positive influence on their smart device addiction, whereas parental self-control and outdoor intentions have no significant influence on it. Moreover, children's social withdrawal and depression have a mediating effect between parental emotion regulation and children's smart device addiction, but parental self-control and outdoor intention have no mediating effect between the two. This study identifies the factors influencing children's smart device addiction from a new perspective, providing theoretical support to address this problem of addiction.
    Language English
    Publishing date 2023-02-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1017772
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Correlation between the facial skin microbiome and sensitive skin using the 2bRAD-M technique.

    Lu, Yi-Na / Cheng, Lu / Shi, Xue-Mei

    International journal of cosmetic science

    2024  

    Abstract: Objective: This study aimed to expound on the correlation between facial skin microbiome and sensitive skin (SS) using a novel sequencing technique.: Methods: We applied the 2bRAD sequencing for the microbiome, which enables accurate characterization ...

    Abstract Objective: This study aimed to expound on the correlation between facial skin microbiome and sensitive skin (SS) using a novel sequencing technique.
    Methods: We applied the 2bRAD sequencing for the microbiome, which enables accurate characterization of the low-biomass microbiome at species resolution to profile facial skin microbes in SS and non-SS groups. Further, the bacterial colonies were isolated and cultured from skin surfaces to study the pro-inflammatory effect on human keratinocytes by ELISA.
    Results: We accordingly identified 1142 genera and 4436 strains. In the SS group, the proportions of Actinomyces and Microbotryomycetes were significantly increased, whereas that of Acidimicrobiia was decreased. Kruskal-Wallis analysis revealed significant differences in 11 genera and 35 species, among which the proportions of Dermabacter, Chryseobacterium, Rhodotorula and Peptoniphilus A were increased in the SS group. Analysis of the top 10 genera revealed increased proportions of Cutibacterium, Corynebacterium and Staphylococcus. Moreover, the proportion of Dermabacter hominis was significantly increased by 18.9-fold in the SS group, whereas those of many Streptococcus strains were significantly decreased. Focus on the isolated bacterial colonies from skin surfaces, more yellow colonies were found in SS group when cultured in Tryptic Soy Broth medium for 48 h, and more interleukin-8 was detected on keratinocytes after yellow colonies stimulation, such as S.capitis, M.luteus.
    Conclusions: This study suggests that more SS-associated microorganisms can be identified using the 2bRAD technique even with a small sample size. Dermabacter hominis and Chryseobacterium was firstly reported with a significantly increase in SS, and the S.capitis, as well as M.luteus, but not S.aureus, may be associated with skin inflammation.
    Language English
    Publishing date 2024-01-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 198917-0
    ISSN 1468-2494 ; 0142-5463
    ISSN (online) 1468-2494
    ISSN 0142-5463
    DOI 10.1111/ics.12941
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  3. Article ; Online: Teaching NeuroImage: Metastatic Urachal Carcinoma in the Extraocular Muscles Mimicking Oculomotor Paralysis.

    Cheng, Lu / Wang, Chungang / Sun, Qiao

    Neurology

    2024  Volume 102, Issue 5, Page(s) e209191

    MeSH term(s) Humans ; Oculomotor Muscles ; Ophthalmoplegia/pathology ; Urinary Bladder Neoplasms/pathology ; Carcinoma ; Paralysis
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000209191
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  4. Article ; Online: Artificial Trachea from Microtissue Engineering and Three-Dimensional Printing for Tracheal Personalized Repair.

    Qi, Chao / Cheng, Lu / Huang, Chuanqi

    Tissue engineering. Part A

    2024  

    Abstract: Millions of people suffer from tracheal defect worldwide each year, while autograft and allograft cannot meet existing treatment needs. Tissue-engineered trachea substitutes represent a promising treatment for tracheal defect, while lack of precisely ... ...

    Abstract Millions of people suffer from tracheal defect worldwide each year, while autograft and allograft cannot meet existing treatment needs. Tissue-engineered trachea substitutes represent a promising treatment for tracheal defect, while lack of precisely personalized treatment abilities. Therefore, development of an artificial trachea that can be used for personalized transplantation is highly desired. In this study, we report the design and fabrication of an artificial trachea based on sericin microsphere (SM) by microtissue engineering technology and three-dimensional (3D) printing for personalized repair of tracheal defect. The SM possessed natural cell adhesion and promoting cell proliferation ability. Then, the microtissue was fabricated by coincubation of SM with chondrocytes and tracheal epithelial cells. This microtissue displayed good cytocompatibility and could support seed cell adhesion and proliferation. After that, this microtissue was individually assembled to form an artificial trachea by 3D printing. Notably, artificial trachea had an encouraging complete cartilaginous and epithelial structure after transplantation. Furthermore, the artificial trachea molecularly resembled native trachea as evidenced by similar expression of trachea-critical genes. Altogether, the work demonstrates the effectiveness of microtissue engineering and 3D printing for individual construction of artificial trachea, providing a promising approach for personalized treatment of tracheal defect.
    Language English
    Publishing date 2024-02-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2420582-5
    ISSN 1937-335X ; 1937-3341
    ISSN (online) 1937-335X
    ISSN 1937-3341
    DOI 10.1089/ten.TEA.2023.0171
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5500/A: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  5. Article ; Online: Hagnifinder

    Hongtai Zhang / Zaiyi Liu / Mingli Song / Cheng Lu

    Journal of Pathology Informatics, Vol 14, Iss , Pp 100302- (2023)

    Recovering magnification information of digital histological images using deep learning

    2023  

    Abstract: Background and objective: Training a robust cancer diagnostic or prognostic artificial intelligent model using histology images requires a large number of representative cases with labels or annotations, which are difficult to obtain. The histology ... ...

    Abstract Background and objective: Training a robust cancer diagnostic or prognostic artificial intelligent model using histology images requires a large number of representative cases with labels or annotations, which are difficult to obtain. The histology snapshots available in published papers or case reports can be used to enrich the training dataset. However, the magnifications of these invaluable snapshots are generally unknown, which limits their usage. Therefore, a robust magnification predictor is required for utilizing those diverse snapshot repositories consisting of different diseases. This paper presents a magnification prediction model named Hagnifinder for H&E-stained histological images. Methods: Hagnifinder is a regression model based on a modified convolutional neural network (CNN) that contains 3 modules: Feature Extraction Module, Regression Module, and Adaptive Scaling Module (ASM). In the training phase, the Feature Extraction Module first extracts the image features. Secondly, the ASM is proposed to address the learned feature values uneven distribution problem. Finally, the Regression Module estimates the mapping between the regularized extracted features and the magnifications. We construct a new dataset for training a robust model, named Hagni40, consisting of 94 643 H&E-stained histology image patches at 40 different magnifications of 13 types of cancer based on The Cancer Genome Atlas. To verify the performance of the Hagnifinder, we measure the accuracy of the predictions by setting the maximum allowable difference values (0.5, 1, and 5) between the predicted magnification and the actual magnification. We compare Hagnifinder with state-of-the-art methods on a public dataset BreakHis and the Hagni40. Results: The Hagnifinder provides consistent prediction accuracy, with a mean accuracy of 98.9%, across 40 different magnifications and 13 different cancer types when Resnet50 is used as the feature extractor. Compared with the state-of-the-art methods focusing on 4–5 levels of ...
    Keywords Histology images ; Magnification prediction ; Regression model ; Deep learning ; Computer applications to medicine. Medical informatics ; R858-859.7 ; Pathology ; RB1-214
    Subject code 006
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Constructing an Indicator System for Cultural Sustainability in Chinese Cities under the Objective of Urban Renewal and Capability Measurement

    Yunxiang Ge / Cheng Lu / Han Gao

    Sustainability, Vol 15, Iss 13571, p

    2023  Volume 13571

    Abstract: Urban renewal is a planning and renovation activity for cities, and pursuing cultural sustainability as a goal of urban renewal can expedite the achievement of high-quality and sustainable urban development. This paper uses the seven elements of cultural ...

    Abstract Urban renewal is a planning and renovation activity for cities, and pursuing cultural sustainability as a goal of urban renewal can expedite the achievement of high-quality and sustainable urban development. This paper uses the seven elements of cultural sustainability—Cultural Heritage (B1), Cultural Vitality (B2), Economic Vitality (B3), Cultural Diversity (B4), Place (B5), Eco-Cultural Resilience (B6), and Eco-Cultural Civilization (B7)—as the core indexes to develop a three-level indicator system applicable to cities with Chinese characteristics. The subjective–objective combination weighting method is then employed to assign weights to the indicators. Among them, Economic Vitality (B3) has the most significant weight, indicating that economic vitality significantly impacts the cultural sustainability of Chinese cities. In addition, the TOPSIS method was employed to assess typical Chinese cities. The assessment demonstrates that our cities can preserve cultural heritage, foster cultural vitality, attract a diverse population, and promote ecological civilization construction. The index system is exhaustive, the selection of indicators is appropriate, and the results of the practical application of the assessment are accurate and effective, allowing it to provide scientific planning guidance for urban renewal.
    Keywords cultural sustainability ; urban renewal ; indicator system ; city measurements ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 720 ; 710
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Whether the addition of high-dosage methylprednisolone to plasma exchange was more effective than plasma exchange in the treatment for severe antineutrophil cytoplasmic antibody-associated vasculitis?

    Cheng, Lu / Gou, Shen-Ju

    Kidney international

    2022  Volume 101, Issue 3, Page(s) 647–648

    MeSH term(s) Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/drug therapy ; Antibodies, Antineutrophil Cytoplasmic/blood ; Humans ; Methylprednisolone ; Plasma Exchange ; Plasmapheresis
    Chemical Substances Antibodies, Antineutrophil Cytoplasmic ; Methylprednisolone (X4W7ZR7023)
    Language English
    Publishing date 2022-02-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2021.11.025
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    Zs.A 797: Show issues Location:
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  8. Article ; Online: The influence of pontic distribution on the marginal and internal gaps of CAD/CAM five-unit anterior zirconia framework.

    Chang, Min-Chieh / Cheng, Lu-Wen / Chuang, Shu-Fen / Chen, Yung-Chung

    Journal of dental sciences

    2024  Volume 19, Issue 2, Page(s) 1105–1115

    Abstract: Background/purpose: Nowadays, zirconia-based framework has been used for longspan or full-arch fixed dental prostheses (FDPs). This study aimed to evaluate the effect of pontic distribution on marginal and internal gaps of five-unit anterior ... ...

    Abstract Background/purpose: Nowadays, zirconia-based framework has been used for longspan or full-arch fixed dental prostheses (FDPs). This study aimed to evaluate the effect of pontic distribution on marginal and internal gaps of five-unit anterior zirconiabased DPs.
    Materials and methods: Right maxillary central incisor and second premolar were selected as terminal abutments and three different edentulous conditions with one nonterminal abutment were simulated. Marginal and internal gaps in each zirconia-based samples(n = 10) were examined by computer-aided replica technique. Five regions, including marginal gaps at mesial or distal finishing line, internal gaps at the mesial or distal axial wall, and occlusal surface, were statistically analyzed (α = .05).
    Results: Most of marginal gaps and internal gaps at axial wall were clinically acceptable, but larger at occlusal surface. For the three experimental groups, clinically accepted percentage with qualified gaps were less than 30%.There were statistical differences at axial wall over pontic side and marginal gaps over non-pontic side between groups (
    Conclusion: Except for occlusal surface, the overall marginal gaps and internal gaps at axial wall of five-unit anterior zirconia-based FDPs with different pontic distribution were clinically acceptable. However, the percentage with qualified gaps were low (<30%). Greater gaps were noted when adjacent pontic existed. Different pontic size and distribution with curvature had an influence on the gaps.
    Language English
    Publishing date 2024-01-16
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2213-8862
    ISSN (online) 2213-8862
    DOI 10.1016/j.jds.2023.12.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Extensive yellowish masses in bilateral orbit and neck.

    Zang, Yinshan / Xu, Lingxiao / Fan, Ran / Cheng, Lu / Xu, Yan

    The Journal of dermatology

    2024  Volume 51, Issue 5, Page(s) e145–e146

    MeSH term(s) Humans ; Neck/pathology ; Male ; Female ; Orbital Diseases/diagnosis ; Orbital Diseases/pathology ; Orbital Diseases/diagnostic imaging ; Orbit/diagnostic imaging ; Orbit/pathology
    Language English
    Publishing date 2024-02-27
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.17166
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  10. Article ; Online: Corrigendum: Exploring the molecular mechanism of hepatitis virus inducing hepatocellular carcinoma by microarray data and immune infiltrates analysis.

    Zhang, Yong-Zheng / Zeb, Amir / Cheng, Lu-Feng

    Frontiers in immunology

    2023  Volume 14, Page(s) 1168774

    Abstract: This corrects the article DOI: 10.3389/fimmu.2022.1032819.]. ...

    Abstract [This corrects the article DOI: 10.3389/fimmu.2022.1032819.].
    Language English
    Publishing date 2023-02-28
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1168774
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