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  1. Article: A Pinprick of Conscience.

    Cherian, Ajith

    Annals of Indian Academy of Neurology

    2023  Volume 26, Issue 4, Page(s) 564

    Language English
    Publishing date 2023-09-11
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.aian_538_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Verbigeration of Oblivious Agony.

    Cherian, Ajith

    Annals of Indian Academy of Neurology

    2023  Volume 26, Issue 2, Page(s) 182

    Language English
    Publishing date 2023-03-17
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.aian_1019_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Art of Guile.

    Cherian, Ajith

    Annals of Indian Academy of Neurology

    2022  Volume 25, Issue 3, Page(s) 493–494

    Language English
    Publishing date 2022-06-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.aian_920_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: "Man in The Broken Mirror".

    Cherian, Ajith

    Annals of Indian Academy of Neurology

    2021  Volume 24, Issue 6, Page(s) 931

    Language English
    Publishing date 2021-12-17
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.aian_692_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Nature's Call and DLBD Phantasm.

    Cherian, Ajith

    Annals of Indian Academy of Neurology

    2021  Volume 24, Issue 2, Page(s) 255

    Language English
    Publishing date 2021-04-23
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.AIAN_113_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Salam to the Techie.

    Cherian, Ajith

    Annals of Indian Academy of Neurology

    2020  Volume 23, Issue 3, Page(s) 357

    Language English
    Publishing date 2020-02-11
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.AIAN_509_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: 'Z Plus Corden' during Covid Times.

    Cherian, Ajith

    Annals of Indian Academy of Neurology

    2020  Volume 23, Issue 5, Page(s) 710

    Language English
    Publishing date 2020-10-07
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.AIAN_397_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: The Ape's Tail.

    Cherian, Ajith

    Annals of Indian Academy of Neurology

    2019  Volume 22, Issue 3, Page(s) 266

    Language English
    Publishing date 2019-03-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/0972-2327.261886
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Pearls & Oy-sters: Grisel Syndrome Presenting as Pseudodystonia: A Twist in the Neck.

    K P, Divya / Cherian, Ajith

    Neurology

    2022  Volume 98, Issue 11, Page(s) 462–465

    Abstract: Pseudodystonia is a term that describes abnormal postures, repetitive movements, or both, where clinical analysis, imaging, laboratory, or electrophysiologic investigations indicate that these movements are not consistent with dystonia. Grisel syndrome ( ... ...

    Abstract Pseudodystonia is a term that describes abnormal postures, repetitive movements, or both, where clinical analysis, imaging, laboratory, or electrophysiologic investigations indicate that these movements are not consistent with dystonia. Grisel syndrome (GS), characterized by rotatory subluxation of the atlantoaxial joint (AAJ) due to nontraumatic causes, is a cause of pseudodystonia. GS is seen in children less than 12 years of age and should be suspected in patients with acute onset of painful torticollis. We report 2 girls, aged 9 and 6 years, who developed painful torticollis following upper respiratory tract infection. They were thought to have cervical dystonia and referred to a movement disorder specialist for botulinum neurotoxin therapy (BoNT). MRI of the cervical spine showed type I and type II rotary AAJ subluxation, respectively, which confirmed the diagnosis of GS. Short tau inversion recovery hyperintensity was noted suggesting AAJ edema without any bone erosion or cord compression. Abruptness of onset, presence of severe pain, resistance to passive neck movements, fixed postures present equally in rest and action, absence of sensory trick, and persistence in sleep favor pseudodystonia. Both subjects improved with conservative treatment, which included temporary immobilization of the cervical spine and anti-inflammatory drugs. Early identification and treatment is imperative to avoid neurologic complications, like high cervical compressive myelopathy, which can lead to quadriplegia and respiratory distress. Prominent sternocleidomastoid contraction ipsilateral to the rotated chin helps to clinically identify GS.
    MeSH term(s) Atlanto-Axial Joint/diagnostic imaging ; Cervical Vertebrae ; Child ; Dystonic Disorders/complications ; Female ; Humans ; Joint Dislocations/complications ; Torticollis/diagnostic imaging ; Torticollis/drug therapy
    Language English
    Publishing date 2022-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000200023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Parkinson's disease - genetic cause.

    Cherian, Ajith / K P, Divya / Vijayaraghavan, Asish

    Current opinion in neurology

    2023  Volume 36, Issue 4, Page(s) 292–301

    Abstract: Purpose of review: Our knowledge of the genetic architecture underlying Parkinson's disease has vastly improved in the past quarter century. About 5-10% of all patients suffer from a monogenic form of Parkinson's disease.: Recent findings: Mutations ... ...

    Abstract Purpose of review: Our knowledge of the genetic architecture underlying Parkinson's disease has vastly improved in the past quarter century. About 5-10% of all patients suffer from a monogenic form of Parkinson's disease.
    Recent findings: Mutations in autosomal dominant genes (e.g. SNCA, LRRK2, VPS35) or autosomal recessive genes (e.g. PRKN, PINK1, DJ-1) can cause genetic Parkinson's disease. Recessive DNAJC6 mutations can present predominantly as atypical parkinsonism, but also rarely as typical Parkinson's disease. Majority of Parkinson's disease is genetically complex. Mutation in RIC3 , a chaperone of neuronal nicotinic acetylcholine receptor subunit α-7 (CHRNA7), provides strong evidence for the role of cholinergic pathway, for the first time, in cause of Parkinson's disease. X-linked parkinsonism manifests at a young age accompanied by many (atypical) features such as intellectual disability, spasticity, seizures, myoclonus, dystonia, and have poor response to levodopa.
    Summary: This review article aims to provide a comprehensive overview on Parkinson's disease genetics. MAPT , which encodes the microtubule associated protein tau, TMEM230, LRP10, NUS1 and ARSA are the five new putative disease-causing genes in Parkinson's disease. The validation of novel genes and its association with Parkinson's disease remains extremely challenging, as genetically affected families are sparse and globally widespread. In the near future, genetic discoveries in Parkinson's disease will influence our ability to predict and prognosticate the disease, help in defining etiological subtypes that are critical in implementation of precision medicine.
    MeSH term(s) Humans ; Parkinson Disease/genetics ; Membrane Proteins/genetics ; Parkinsonian Disorders/genetics ; Mutation/genetics ; Seizures ; LDL-Receptor Related Proteins/genetics ; Receptors, Cell Surface/genetics
    Chemical Substances Membrane Proteins ; LRP10 protein, human ; LDL-Receptor Related Proteins ; NUS1 protein, human ; Receptors, Cell Surface
    Language English
    Publishing date 2023-05-24
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1182686-1
    ISSN 1473-6551 ; 1350-7540
    ISSN (online) 1473-6551
    ISSN 1350-7540
    DOI 10.1097/WCO.0000000000001167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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