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  1. Article ; Online: Open Access Budget Impact Assessment Tools: A Welcome Step in Supporting Evidence-Informed Policy Decisions.

    Chew, Derek / Clement, Fiona

    The Canadian journal of cardiology

    2022  Volume 38, Issue 10, Page(s) 1485–1487

    MeSH term(s) Access to Information ; Cost-Benefit Analysis ; Health Policy ; Humans
    Language English
    Publishing date 2022-09-12
    Publishing country England
    Document type Editorial
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2022.07.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Diagnosis and management of acute coronary syndromes.

    Eng-Frost, Joanne / Chew, Derek

    Australian prescriber

    2021  Volume 44, Issue 6, Page(s) 180–184

    Abstract: Acute coronary syndromes are a significant cause of morbidity and mortality in Australia. Outcomes are likely to be improved by rapid and accurate diagnosis, and early intervention The development of high-sensitivity troponin assays has revealed ... ...

    Abstract Acute coronary syndromes are a significant cause of morbidity and mortality in Australia. Outcomes are likely to be improved by rapid and accurate diagnosis, and early intervention The development of high-sensitivity troponin assays has revealed previously unrecognised types of myocardial injury, for which conventional management guidelines for myocardial infarction may not confer similar benefits. The distinction between myocardial injury and myocardial infarction has therefore become increasingly important Once the diagnosis of acute myocardial infarction has been made, individualised acute reperfusion strategies including percutaneous coronary intervention or fibrinolytic therapy should be considered. Secondary prevention strategies should be implemented before hospital discharge.
    Language English
    Publishing date 2021-12-01
    Publishing country Australia
    Document type Journal Article ; Review
    ZDB-ID 1075442-8
    ISSN 0312-8008
    ISSN 0312-8008
    DOI 10.18773/austprescr.2021.049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Long-term oral anticoagulant after catheter ablation for atrial fibrillation.

    Chew, Derek / Piccini, Jonathan P

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2021  Volume 23, Issue 8, Page(s) 1157–1165

    Abstract: Catheter ablation is superior to antiarrhythmic therapy for the reduction of symptomatic atrial fibrillation (AF), recurrence, and burden. The possibility of a true 'rhythm' control strategy with catheter ablation has re-opened the debate on rate vs. ... ...

    Abstract Catheter ablation is superior to antiarrhythmic therapy for the reduction of symptomatic atrial fibrillation (AF), recurrence, and burden. The possibility of a true 'rhythm' control strategy with catheter ablation has re-opened the debate on rate vs. rhythm control and the subsequent impact on stroke risk. Some observation studies suggest that successful AF catheter ablation and maintenance of sinus rhythm are associated with a decrease in stroke risk, while the CABANA trial had demonstrated no apparent reduction. Other observational studies have demonstrated increased stroke risk when oral anticoagulation (OAC) is discontinued after catheter ablation. When and in whom OAC can be discontinued after ablation will need to be determined in properly conducted randomized control trials. In this review article, we discuss our current understanding of the interactions between AF, stroke, and anticoagulation following catheter ablation. Specifically, we discuss the evidence for the long-term anticoagulation following successful catheter ablation, the potential for OAC discontinuation with restoration of sinus rhythm, and novel approaches to anticoagulation management post-ablation.
    MeSH term(s) Anti-Arrhythmia Agents ; Anticoagulants/adverse effects ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/surgery ; Catheter Ablation/adverse effects ; Humans ; Stroke/etiology ; Stroke/prevention & control ; Treatment Outcome
    Chemical Substances Anti-Arrhythmia Agents ; Anticoagulants
    Language English
    Publishing date 2021-01-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/euaa365
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Ocular MPox: A report of two cases.

    Bhamray-Sanchez, Devina / Subramanian, Shyamala / Dever, Lisa L / Chew, Debra

    IDCases

    2023  Volume 31, Page(s) e01706

    Abstract: We report two cases of ocular MPox in men living with HIV, and review the clinical manifestations, diagnosis, and treatment of this rare syndrome. Our cases highlight the need for early recognition and prompt treatment for this potentially sight ... ...

    Abstract We report two cases of ocular MPox in men living with HIV, and review the clinical manifestations, diagnosis, and treatment of this rare syndrome. Our cases highlight the need for early recognition and prompt treatment for this potentially sight threatening infection.
    Language English
    Publishing date 2023-02-01
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2023.e01706
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: New Osia® OSI200 active transcutaneous bone-anchored hearing device: how I do it.

    Chew, Dylan / Proctor, Vicki / Ray, Jaydip

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2022  Volume 280, Issue 2, Page(s) 935–939

    Abstract: Introduction: The new Osia® OSI200 implant incorporates a receiver coil and Piezo Power™ Transducer into one monolithic unit. Appropriate planning and surgical approach is needed for suitable positioning of the device.: Method: To optimise the ... ...

    Abstract Introduction: The new Osia® OSI200 implant incorporates a receiver coil and Piezo Power™ Transducer into one monolithic unit. Appropriate planning and surgical approach is needed for suitable positioning of the device.
    Method: To optimise the surgical field and provide tension-free wound closure our team have adopted a versatile 'Sheffield-S' post-auricular incision which remains hidden within the hairline.
    Conclusion: This incision provides adequate exposure for device placement and bone polishing/recessing. The soft tissue approach has resulted in improved operative efficacy particularly in those patients with irregular cortical bone or where pre-existing osseointegrated implants need to be removed or avoided.
    MeSH term(s) Humans ; Bone-Anchored Prosthesis ; Hearing Aids ; Bone Conduction ; Hearing ; Hearing Tests ; Hearing Loss, Conductive/surgery ; Treatment Outcome
    Language English
    Publishing date 2022-12-19
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-022-07786-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Challenges in measuring gender identity among transgender, gender diverse, and non-binary young people.

    Blacklock, C / McGlasson, C / Chew, D / Murfitt, K / Hoq, M

    Public health

    2021  Volume 200, Page(s) e4–e5

    MeSH term(s) Adolescent ; Female ; Gender Identity ; Humans ; Male ; Transgender Persons
    Language English
    Publishing date 2021-10-16
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 427333-3
    ISSN 1476-5616 ; 0033-3506
    ISSN (online) 1476-5616
    ISSN 0033-3506
    DOI 10.1016/j.puhe.2021.09.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Multidimensional Scaling of Varietal Data in Sedimentary Provenance Analysis

    Vermeesch, P. / Lipp, A. G. / Hatzenbühler, D. / Caracciolo, L. / Chew, D.

    Journal of Geophysical Research: Earth Surface. 2023 Mar., v. 128, no. 3 p.e2022JF006992-

    2023  

    Abstract: Varietal studies of sedimentary provenance use the properties of individual minerals or mineral groups. These are recorded as lists of numerical tables that can be difficult to interpret. Multidimensional Scaling (MDS) is a popular multivariate ... ...

    Abstract Varietal studies of sedimentary provenance use the properties of individual minerals or mineral groups. These are recorded as lists of numerical tables that can be difficult to interpret. Multidimensional Scaling (MDS) is a popular multivariate ordination technique for analyzing other types of provenance data based on, for example, detrital geochronology or petrography. Applying MDS to varietal data would allow them to be treated on an equal footing with those other provenance proxies. MDS requires a method to quantify the dissimilarity between two samples. This paper introduces three ways to do so. The first method (“treatment‐by‐row”) turns lists of (compositional) data tables into lists of vectors, using principal component analysis. These lists of vectors can then be treated as “distributional” data and subjected to MDS analysis using dissimilarity measures such as the Kolmogorov‐Smirnov statistic. The second method (“treatment‐by‐column”) turns lists of compositional data tables into multiple lists of vectors, each representing a single component of the varietal data. These multiple distributional data sets are subsequently subjected to Procrustes analysis or 3‐way MDS. The third method uses the Wasserstein‐2 distance to jointly compare the rows and columns of varietal data. This arguably makes the best use of the data but acts more like a “black box” than the other two methods. Applying the three methods to a detrital titanite data set from Colombia yields similar results. After converting varietal data to dissimilarity matrices, they can be combined with other types of provenance data, again using Procrustes analysis or 3‐way MDS.
    Keywords data collection ; geochronology ; geophysics ; principal component analysis ; provenance ; research ; Colombia
    Language English
    Dates of publication 2023-03
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ISSN 2169-9003
    DOI 10.1029/2022JF006992
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: The influence of Cenozoic Eurasia-Arabia convergence on the Southeast Arabian Foreland Basin: new geochronological and geochemical constraints from syn-kinematic carbonate mineralization.

    Arboit, Francesco / Drost, Kerstin / Decarlis, Alessandro / Chew, David / Hennhoefer, Dominik / Ceriani, Andrea

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 4387

    Abstract: The Cenozoic succession of the Jabal Hafeet anticline yields the most complete surface expression of the deformation that affected the Southeast Arabian Foreland Basin (SEAFB). The carbonate rocks of the Eocene Rus Formation comprise the core of the ... ...

    Abstract The Cenozoic succession of the Jabal Hafeet anticline yields the most complete surface expression of the deformation that affected the Southeast Arabian Foreland Basin (SEAFB). The carbonate rocks of the Eocene Rus Formation comprise the core of the Jabal Hafeet anticline and host a network of fractures and carbonate veins associated with dynamic fracture opening and sealing events. These fracture networks developed during the propagation of compressional stresses from the Makran and Zagros fold-and-thrust belts into their foreland basin system (the SEAFB) and are associated with Arabia-Eurasia convergence. Syn-kinematic calcite veins associated with the Cenozoic folding events in the SEAFB were dated by U-Pb LA-ICP-MS carbonate geochronology and characterized further by Raman fluid-inclusion geochemistry. The U-Pb data show that Cenozoic compression linked to the propagation of the Makran fold-and-thrust belt into the SEAFB took place from c. 20 Ma (early Miocene) to c. 2 Ma (mid Pleistocene). Raman fluid-inclusion data reveal the presence of complex hydrocarbons within the parent carbonate-bearing fluids, reflecting a fluid transport pathway between the upper Cenozoic rocks and deeper hydrocarbon-bearing Mesozoic sequences. Combined isotopic and geochemical datasets show that the deformational history of the SEAFB is likely related to the reactivation of inherited deep-seated structures in the upper Cenozoic stratigraphic sequence due to the far-field stress propagation from the Makran belt into the Arabian peninsula, rather than the propagation of a thin-skinned deformation architecture.
    Language English
    Publishing date 2023-03-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-31611-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Outcome trial data on sodium glucose cotransporter-2 inhibitors: Putting clinical benefits and risks in perspective.

    Chiang, B / Chew, D P / De Pasquale, C G

    International journal of cardiology

    2021  Volume 349, Page(s) 96–98

    Abstract: Background: Sodium glucose cotransporter-2 (SGLT2) inhibitors have significant heart failure and renoprotective benefits with a wide spectrum of unfamiliar and potentially serious adverse effects. Limited understanding of the risk-benefit profile of ... ...

    Abstract Background: Sodium glucose cotransporter-2 (SGLT2) inhibitors have significant heart failure and renoprotective benefits with a wide spectrum of unfamiliar and potentially serious adverse effects. Limited understanding of the risk-benefit profile of SGLT2 inhibitor treatment may result in under utilisation by prescribers and patients.
    Methods: Data from recent seminal randomized, placebo-controlled, outcome trials for multiple SGLT2 inhibitors were incorporated. Trial populations were sub-classified into high cardiovascular risk T2DM, HFrEF, and CKD. Efficacy outcomes of heart failure hospitalisation (HFH), cardiovascular (CV) mortality, total mortality, and prevention of renal deterioration were examined. Safety outcomes included were major hypoglycaemia, diabetic ketoacidosis (DKA), urinary tract infections (UTI), mycotic genital infections (MGI), hypotension, amputations and fractures. Absolute risk reduction/increase were used to calculate number needed to treat/harm.
    Results: Trial data comprised 71,545 patients, of which 53,144 were high risk T2DM, 9696 HFrEF and 8705 CKD. For HFrEF, NNT for HFH was 18, CV mortality 93, total mortality 76, prevention of renal deterioration 143 and prevention of DKA 6224. NNH for UTI was 557, MGI 356, hypotension 120, hypoglycaemia 574, amputations 707 and fractures 858. For CKD, NNT for HFH was 116, CV mortality 245, total mortality 138, and prevention of renal deterioration was 63. NNH for DKA was 1458, UTI 309, MGI 291, hypotension 165, hypoglycaemia 374, amputations 4450 and fractures 696. In the T2DM cohort, NNT for HFH was 139, CV mortality 851, total mortality 601 and prevention of renal deterioration 558. NNH DKA was 1525, UTI 239, MGI 69, hypotension 325, hypoglycaemia 472, amputations 1578 and fractures 9569.
    Conclusions and relevance: The cardiovascular and renal protective benefits of SGLT2 inhibitors far outweigh the risks. This paper puts into perspective the benefits and risks of treatment with SGLT2 inhibitors for clinicians and patients.
    MeSH term(s) Diabetes Mellitus, Type 2/drug therapy ; Heart Failure ; Humans ; Hypoglycemic Agents/adverse effects ; Risk Assessment ; Sodium-Glucose Transporter 2 Inhibitors/adverse effects ; Stroke Volume
    Chemical Substances Hypoglycemic Agents ; Sodium-Glucose Transporter 2 Inhibitors
    Language English
    Publishing date 2021-12-15
    Publishing country Netherlands
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2021.12.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Differences in outcomes for hospitalizations of systemic and non-systemic infections associated with vascular and cardiac grafts and devices: a population-based study.

    Mponponsuo, K / Chew, D / Lu, S / Somayaji, R / Rennert-May, E

    The Journal of hospital infection

    2020  Volume 106, Issue 4, Page(s) 828–834

    Abstract: Background: Use of vascular and cardiac devices has expanded and is associated with a relative, though disproportionate, increase in device-associated infections.: Aim: To describe the association between cardiac/vascular device infections and ... ...

    Abstract Background: Use of vascular and cardiac devices has expanded and is associated with a relative, though disproportionate, increase in device-associated infections.
    Aim: To describe the association between cardiac/vascular device infections and outcomes in those with, and without systemic infections.
    Methods: We used the 2016 National Inpatient Sample and the International Classification of Diseases - 10
    Findings: There were a total of 65,110 hospitalizations associated with device infections with a mean age of 61.3 ± 15.9 years (standard deviation); 28,650 (44%) had systemic infections. Elixhauser comorbidity scores of three or greater were observed in 91.2% of individuals with systemic infections along with a higher prevalence of diabetes, renal disease and heart failure. The primary outcome of mortality was observed in 3965 individuals with an odds ratio of 3.97 (95% confidence interval (CI), 2.92-3.95) in those with systemic infections compared with those without. Mean LOS was 3.44 days longer (95% CI, 2.92-3.95) and mean cost was US$11,776 greater (95% CI, US$9826-12,727) in the systemic infection cohort.
    Conclusion: Systemic cardiac and vascular device infections were associated with increased mortality, LOS and costs. Considering the increasing use of these life-saving devices, further work is needed to identify those at risk for infectious complications, particularly systemic infection, in order to enhance preventative strategies and improve health outcomes.
    MeSH term(s) Aged ; Heart Transplantation/adverse effects ; Hospitalization ; Humans ; Length of Stay ; Middle Aged ; Odds Ratio ; Prosthesis-Related Infections/epidemiology ; Prosthesis-Related Infections/mortality ; United States ; Vascular Grafting/adverse effects
    Language English
    Publishing date 2020-09-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 779366-2
    ISSN 1532-2939 ; 0195-6701
    ISSN (online) 1532-2939
    ISSN 0195-6701
    DOI 10.1016/j.jhin.2020.09.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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