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  1. AU="Chia, Jasmine Siew Min"
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  1. Article ; Online: Anthropometric indices, but not birth weight, are associated with high blood pressure risk among Malay adolescents in Kuala Lumpur.

    Poh, Bee Koon / Ang, Yeow Nyin / Yeo, Giin Shang / Lee, Yong Zhuan / Lee, Shoo Thien / Chia, Jasmine Siew Min / Wee, Bee Suan

    Dialogues in health

    2022  Volume 1, Page(s) 100006

    Abstract: Background: With the high prevalence of hypertension, it is important to determine its predictors early. The aim of this study was to determine the association between blood pressure with anthropometric indices and birth weight among a population of ... ...

    Abstract Background: With the high prevalence of hypertension, it is important to determine its predictors early. The aim of this study was to determine the association between blood pressure with anthropometric indices and birth weight among a population of Malay adolescents in Kuala Lumpur.
    Design and methods: This cross-sectional study was carried out among 254 primary and secondary school adolescents aged 10 to 16 years. Anthropometric measurements and blood pressure were determined through standardized protocols, while participants' birth weight was obtained from birth certificate. Body mass index (BMI), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR) and a body shape index (ABSI) were calculated.
    Results: Boys had significantly higher weight, height, WC, WHtR and systolic blood pressure (SBP) than girls (
    Conclusion: BMI had the best predictive ability for SBP and DBP. These findings strongly emphasize the importance of primary prevention of hypertension in adolescents, especially among those with high BMI.
    Language English
    Publishing date 2022-03-04
    Publishing country United States
    Document type Journal Article
    ISSN 2772-6533
    ISSN (online) 2772-6533
    DOI 10.1016/j.dialog.2022.100006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Zerumbone-Induced Analgesia Modulated via Potassium Channels and Opioid Receptors in Chronic Constriction Injury-Induced Neuropathic Pain.

    Gopalsamy, Banulata / Chia, Jasmine Siew Min / Farouk, Ahmad Akira Omar / Sulaiman, Mohd Roslan / Perimal, Enoch Kumar

    Molecules (Basel, Switzerland)

    2020  Volume 25, Issue 17

    Abstract: Zerumbone, a monocyclic sesquiterpene from the wild ginger ... ...

    Abstract Zerumbone, a monocyclic sesquiterpene from the wild ginger plant
    MeSH term(s) Analgesia ; Animals ; Disease Models, Animal ; Male ; Mice ; Mice, Inbred ICR ; Narcotic Antagonists/chemistry ; Narcotic Antagonists/pharmacology ; Neuralgia/drug therapy ; Neuralgia/metabolism ; Neuralgia/pathology ; Potassium Channel Blockers/chemistry ; Potassium Channel Blockers/pharmacology ; Potassium Channels/metabolism ; Receptors, Opioid/metabolism ; Sesquiterpenes/chemistry ; Sesquiterpenes/pharmacology
    Chemical Substances Narcotic Antagonists ; Potassium Channel Blockers ; Potassium Channels ; Receptors, Opioid ; Sesquiterpenes ; zerumbone (471-05-6)
    Language English
    Publishing date 2020-08-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules25173880
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Zerumbone Ameliorates Neuropathic Pain Symptoms via Cannabinoid and PPAR Receptors Using In Vivo and In Silico Models.

    Chia, Jasmine Siew Min / Farouk, Ahmad Akira Omar / Mohamad, Tengku Azam Shah Tengku / Sulaiman, Mohd Roslan / Zakaria, Hanis / Hassan, Nurul Izzaty / Perimal, Enoch Kumar

    Molecules (Basel, Switzerland)

    2021  Volume 26, Issue 13

    Abstract: Neuropathic pain is a chronic pain condition persisting past the presence of any noxious stimulus or inflammation. Zerumbone, of ... ...

    Abstract Neuropathic pain is a chronic pain condition persisting past the presence of any noxious stimulus or inflammation. Zerumbone, of the
    MeSH term(s) Animals ; Disease Models, Animal ; Male ; Mice ; Mice, Inbred ICR ; Neuralgia/drug therapy ; Neuralgia/metabolism ; Neuralgia/pathology ; PPAR alpha/antagonists & inhibitors ; PPAR alpha/metabolism ; PPAR gamma/antagonists & inhibitors ; PPAR gamma/metabolism ; Receptor, Cannabinoid, CB1/antagonists & inhibitors ; Receptor, Cannabinoid, CB1/metabolism ; Receptor, Cannabinoid, CB2/antagonists & inhibitors ; Receptor, Cannabinoid, CB2/metabolism ; Sesquiterpenes/pharmacology
    Chemical Substances PPAR alpha ; PPAR gamma ; Ppara protein, mouse ; Pparg protein, mouse ; Receptor, Cannabinoid, CB1 ; Receptor, Cannabinoid, CB2 ; Sesquiterpenes ; zerumbone (471-05-6)
    Language English
    Publishing date 2021-06-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules26133849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Zerumbone Modulates α

    Chia, Jasmine Siew Min / Izham, Noor Aishah Mohammed / Farouk, Ahmad Akira Omar / Sulaiman, Mohd Roslan / Mustafa, Sanam / Hutchinson, Mark R / Perimal, Enoch Kumar

    Frontiers in pharmacology

    2020  Volume 11, Page(s) 92

    Abstract: Zerumbone has shown great potential in various pathophysiological models of diseases, particularly in neuropathic pain conditions. Further understanding the mechanisms of action is important to develop zerumbone as a potential anti-nociceptive agent. ... ...

    Abstract Zerumbone has shown great potential in various pathophysiological models of diseases, particularly in neuropathic pain conditions. Further understanding the mechanisms of action is important to develop zerumbone as a potential anti-nociceptive agent. Numerous receptors and pathways function to inhibit and modulate transmission of pain signals. Previously, we demonstrated involvement of the serotonergic system in zerumbone's anti-neuropathic effects. The present study was conducted to determine zerumbone's modulatory potential involving noradrenergic, transient receptor potential vanilloid type 1 (TRPV1) and
    Language English
    Publishing date 2020-03-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2020.00092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Triple burden of malnutrition among Malaysian children aged 6 months to 12 years: Current findings from SEANUTS II Malaysia.

    Poh, Bee Koon / Wong, Jyh Eiin / Lee, Shoo Thien / Chia, Jasmine Siew Min / Yeo, Giin Shang / Sharif, Razinah / Nik Shanita, Safii / Jamil, Nor Aini / Chan, Caryn Mei Hsien / Farah, Nor Mf / Sameeha, Mohd Jamil / Koh, Denise / Saat, Nur Zakiah Mohd / Lim, See Meng / Norimah, A Karim / Ruzita, Abd Talib / Budin, Siti Balkis / Wee, Lei Hum / Tang, Swee Fong /
    Khouw, Ilse

    Public health nutrition

    2023  , Page(s) 1–36

    Abstract: Objective: This paper aims to report South East Asian Nutrition Surveys (SEANUTS) II Malaysia data on nutritional status, dietary intake, and nutritional biomarkers of children aged 6 months to 12 years.: Design: Cross-sectional survey conducted in ... ...

    Abstract Objective: This paper aims to report South East Asian Nutrition Surveys (SEANUTS) II Malaysia data on nutritional status, dietary intake, and nutritional biomarkers of children aged 6 months to 12 years.
    Design: Cross-sectional survey conducted in 2019-2020.
    Setting: Multistage cluster sampling conducted in Central, Northern, Southern, and East Coast regions of Peninsular Malaysia.
    Participants: 2989 children aged 0.5-12.9 years.
    Results: Prevalences of stunting, thinness, overweight, and obesity among children aged 0.5-12.9 years were 8.9%, 6.7%, 9.2%, and 8.8%, respectively. Among children below 5 years old, 11.4% were underweight, 13.8% had stunting, and 6.2% wasting. Data on nutritional biomarkers showed a small proportion of children aged 4-12 years had iron (2.9%) and vitamin A deficiencies (3.1%). Prevalence of anaemia was distinctly different between children below 4 years old (40.3%) and those aged 4 years and above (3.0%). One-fourth of children (25.1%) had vitamin D insufficiency, which was twice as prevalent in girls (35.2% vs. boys: 15.6%). The majority of children did not meet the recommended dietary intake for calcium (79.4%) and vitamin D (94.8%).
    Conclusions: Data from SEANUTS II Malaysia confirmed that triple burden of malnutrition co-exists among children in Peninsular Malaysia, with higher prevalence of overnutrition than undernutrition. Anaemia is highly prevalent among children below 4 years old, while vitamin D insufficiency is more prevalent among girls. Low intakes of dietary calcium and vitamin D are also of concern. These findings provide policymakers with useful and evidence-based data to formulate strategies that address the nutritional issues of Malaysian children.
    Language English
    Publishing date 2023-11-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 1436024-x
    ISSN 1475-2727 ; 1368-9800
    ISSN (online) 1475-2727
    ISSN 1368-9800
    DOI 10.1017/S1368980023002239
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Zerumbone alleviates chronic constriction injury-induced allodynia and hyperalgesia through serotonin 5-HT receptors.

    Chia, Jasmine Siew Min / Omar Farouk, Ahmad Akira / Mohamad, Azam Shah / Sulaiman, Mohd Roslan / Perimal, Enoch Kumar

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2016  Volume 83, Page(s) 1303–1310

    Abstract: Zerumbone, a bioactive sesquiterpene isolated from Zingiber zerumbet (Smith), has shown to exert antiallodynic and antihyperalgesic effects in neuropathic pain mice model in our recent study. The mechanism through which zerumbone alleviates neuropathic ... ...

    Abstract Zerumbone, a bioactive sesquiterpene isolated from Zingiber zerumbet (Smith), has shown to exert antiallodynic and antihyperalgesic effects in neuropathic pain mice model in our recent study. The mechanism through which zerumbone alleviates neuropathic pain has yet to be elucidated. Thus, this study aimed to determine whether the serotonergic system, part of the descending pain modulation pathway, contributes to the antineuropathic effect of zerumbone. Participation of the serotonergic system in zerumbone-induced antiallodynia and antihyperalgesia was assessed using Dynamic Plantar Aesthesiometer von Frey test and Hargreaves plantar test respectively in chronic-constriction injury mice model. Administration of ρ-chlorophenylalanine (PCPA, 100mg/kg, i.p.) for four consecutive days to deplete serotonin (5-HT) prior to zerumbone administration blocked the antiallodynic and antihyperalgesic effects of zerumbone. Further investigation with 5-HT receptor antagonists methiothepin (5-HT
    MeSH term(s) Animals ; Chronic Disease ; Constriction ; Zingiber officinale ; Hyperalgesia/drug therapy ; Male ; Mice ; Mice, Inbred ICR ; Neuralgia/drug therapy ; Plant Extracts/isolation & purification ; Plant Extracts/therapeutic use ; Receptors, Serotonin/physiology ; Serotonin Antagonists/isolation & purification ; Serotonin Antagonists/therapeutic use ; Sesquiterpenes/isolation & purification ; Sesquiterpenes/therapeutic use
    Chemical Substances Plant Extracts ; Receptors, Serotonin ; Serotonin Antagonists ; Sesquiterpenes ; zerumbone (471-05-6)
    Language English
    Publishing date 2016-08-27
    Publishing country France
    Document type Journal Article
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2016.08.052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Experimental Characterization of the Chronic Constriction Injury-Induced Neuropathic Pain Model in Mice.

    Gopalsamy, Banulata / Sambasevam, Yogesvari / Zulazmi, Nurul Atiqah / Chia, Jasmine Siew Min / Omar Farouk, Ahmad Akira / Sulaiman, Mohd Roslan / Tengku Mohamad, Tengku Azam Shah / Perimal, Enoch Kumar

    Neurochemical research

    2019  Volume 44, Issue 9, Page(s) 2123–2138

    Abstract: Number of ligations made in the chronic constriction injury (CCI) neuropathic pain model has raised serious concerns. We compared behavioural responses, nerve morphology and expression of pain marker, c-fos among CCI models developed with one, two, three ...

    Abstract Number of ligations made in the chronic constriction injury (CCI) neuropathic pain model has raised serious concerns. We compared behavioural responses, nerve morphology and expression of pain marker, c-fos among CCI models developed with one, two, three and four ligations. The numbers of ligation(s) on sciatic nerve shows no significant difference in displaying mechanical and cold allodynia, and mechanical and thermal hyperalgesia throughout 84 days. All groups underwent similar levels of nerve degeneration post-surgery. Similar c-fos level in brain cingulate cortex, parafascicular nuclei and amygdala were observed in all CCI models compared to sham-operated group. Therefore, number of ligations does not impact intensity of pain symptoms, pathogenesis and neuronal activation. A single ligation is sufficient to develop neuropathic pain, in contrast to the established model of four ligations. This study dissects and characterises the CCI model, ascertaining a more uniform animal model to surrogate actual neuropathic pain condition.
    MeSH term(s) Amygdala/metabolism ; Amygdala/pathology ; Amygdala/physiopathology ; Animals ; Constriction, Pathologic/complications ; Disease Models, Animal ; Gyrus Cinguli/metabolism ; Gyrus Cinguli/pathology ; Hyperalgesia/metabolism ; Hyperalgesia/physiopathology ; Intralaminar Thalamic Nuclei/metabolism ; Intralaminar Thalamic Nuclei/pathology ; Ligation ; Male ; Mice, Inbred ICR ; Neuralgia/etiology ; Neuralgia/metabolism ; Neuralgia/pathology ; Neuralgia/physiopathology ; Pain Measurement ; Proto-Oncogene Proteins c-fos/metabolism ; Sciatic Nerve/injuries ; Sciatic Nerve/pathology ; Sciatic Neuropathy/etiology ; Sciatic Neuropathy/metabolism ; Sciatic Neuropathy/pathology ; Sciatic Neuropathy/physiopathology
    Chemical Substances Proto-Oncogene Proteins c-fos
    Language English
    Publishing date 2019-08-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 199335-5
    ISSN 1573-6903 ; 0364-3190
    ISSN (online) 1573-6903
    ISSN 0364-3190
    DOI 10.1007/s11064-019-02850-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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