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  1. Article ; Online: Doxycycline

    Chiara Bonzano / Davide Borroni / Andrea Lancia / Elisabetta Bonzano

    Frontiers in Medicine, Vol

    From Ocular Rosacea to COVID-19 Anosmia. New Insight Into the Coronavirus Outbreak

    2020  Volume 7

    Keywords COVID-19 ; doxycycline ; coronavirus (CoV) ; SARS – CoV ; anosmia ; Medicine (General) ; R5-920 ; covid19
    Language English
    Publishing date 2020-05-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  2. Article ; Online: Delayed Re-epithelialization After Epithelium-Off Crosslinking

    Chiara Bonzano / Carlo Alberto Cutolo / Donatella Musetti / Ilaria Di Mola / Chiara Pizzorno / Riccardo Scotto / Carlo Enrico Traverso

    Frontiers in Medicine, Vol

    Predictors and Impact on Keratoconus Progression

    2021  Volume 8

    Abstract: Purpose: To investigate the demographic and corneal factors associated with the occurrence of delayed reepithelialization (DRE) after epithelium-off crosslinking (epi-off CXL).Design:Retrospective case series.Methods:A chart review was performed to ... ...

    Abstract Purpose: To investigate the demographic and corneal factors associated with the occurrence of delayed reepithelialization (DRE) after epithelium-off crosslinking (epi-off CXL).Design:Retrospective case series.Methods:A chart review was performed to identify patients treated with epi-off CXL. DRE was defined as a corneal epithelial defect detected by fluorescein staining that persisted for more than 10 days. Slit-lamp examination, anterior segment optical coherence tomography, corneal topography, and corneal in vivo confocal microscopy (IVCM) were always performed preoperatively and at each follow-up visit (1, 3, 6, 12 months). A generalized estimating equation was used to assess the baseline factors associated with DRE.Results:Data from 153 eyes were analyzed. The mean age of patients was 24.9 ± 8.5 years, and 47 (30.7%) were women. The average reepithelization time was 4.7 ± 1.8 days. Six eyes (3.9%) experienced DRE. In the multivariate model, both the age of the patient (OR = 1.30; p = 0.02) and the corneal steepest meridian (OR = 0.44, p = 0.047) were associated with DRE. Baseline nerve count was also associated with DRE (0.87, p = 0.03). Male gender was associated with a slower early nerve regrowth (1–6 months) (p = 0.048), but not with the occurrence of DRE (p = 0.27). Preoperative central corneal thickness was not related to DRE (p = 0.16). DRE was not associated with keratoconus progression after epi-off CXL (p = 0.520).Conclusions:The association between DRE and age may reflect the age-related decrease in the corneal healing response. Also, low baseline corneal nerve count is associated with DRE. Gender seems to affect reinnervation measured by IVCM but not the reepithelization time. DRE does not seem to affect the efficacy of epi-off CXL.
    Keywords epithelium-off crosslinking ; accelerated corneal crosslinking ; keratoconus ; delayed re-epithelialization ; bandage contact lens ; Medicine (General) ; R5-920
    Subject code 616
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Moving beyond the Slit-Lamp Gonioscopy

    Carlo Alberto Cutolo / Chiara Bonzano / Riccardo Scotto / Michele Iester / Alessandro Bagnis / Chiara Pizzorno / Carlo Catti / Carlo Enrico Traverso

    Diagnostics, Vol 11, Iss 2279, p

    Challenges and Future Opportunities

    2021  Volume 2279

    Abstract: After almost a century from its introduction in clinical practice, slit-lamp gonioscopy is still considered the reference standard for evaluating the anterior chamber angle (ACA). Gonioscopy is essential for diagnosing angle closure disease, and ACA ... ...

    Abstract After almost a century from its introduction in clinical practice, slit-lamp gonioscopy is still considered the reference standard for evaluating the anterior chamber angle (ACA). Gonioscopy is essential for diagnosing angle closure disease, and ACA features are included in glaucoma’s diagnostics and treatments algorithms. However, shortcomings of slit-lamp gonioscopy include a steep learning curve, lack of agreement between examiners and poor documentation. Thanks to advances in miniaturization and computing, new instruments for digital gonioscopy have been developed and marketed. This narrative review focuses on the Gonioscope GS-1, which permits semi-automated circumferential documentation of the ACA in real-colour photographs. Advantages and disadvantages of GS-1 compared with slit-lamp gonioscopy and other ACA imaging technologies such as optical coherence tomography are discussed. Finally, potential opportunities offered by this device for telemedicine, virtual clinics, and automatic classification with deep learning are presented.
    Keywords gonioscopy ; anterior chamber angle ; iridocorneal angle ; Medicine (General) ; R5-920
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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  4. Article ; Online: Globe salvage treatment in group D and group E retinoblastoma.

    Hussain, Ahmad Khaqan / Rahul, Rachwani Anil / Carlos, Rocha de Lossada / Francisco, Zamorano Martín / María, García Lorente / Flavia, Pennisi / Chiara, Bonzano / Davide, Borroni

    Romanian journal of ophthalmology

    2021  Volume 65, Issue 1, Page(s) 20–24

    Abstract: Importance: ...

    Abstract Importance:
    MeSH term(s) Adult ; Combined Modality Therapy ; Cryotherapy/methods ; Eye Enucleation/methods ; Female ; Follow-Up Studies ; Humans ; Infusions, Intravenous ; Male ; Melphalan/administration & dosage ; Myeloablative Agonists/administration & dosage ; Neoplasm Staging ; Retinal Neoplasms/diagnosis ; Retinal Neoplasms/therapy ; Retinoblastoma/diagnosis ; Retinoblastoma/therapy ; Retrospective Studies ; Salvage Therapy/methods ; Treatment Outcome
    Chemical Substances Myeloablative Agonists ; Melphalan (Q41OR9510P)
    Language English
    Publishing date 2021-02-04
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 2842202-8
    ISSN 2501-2533 ; 2457-4325
    ISSN (online) 2501-2533
    ISSN 2457-4325
    DOI 10.22336/rjo.2021.5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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