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  1. Article ; Online: Lack of Biological Plausibility and Major Methodological Issues Cast Doubt on the Association between Aspartame and Autism. Comment on Fowler et al. Daily Early-Life Exposures to Diet Soda and Aspartame Are Associated with Autism in Males: A Case-Control Study.

    Ayoub-Charette, Sabrina / Khan, Tauseef Ahmad / Chiavaroli, Laura / Magnuson, Bernadene A / Sievenpiper, John L

    Nutrients

    2024  Volume 16, Issue 5

    Abstract: The case-control study by Fowler et al [ ... ]. ...

    Abstract The case-control study by Fowler et al [...].
    MeSH term(s) Male ; Humans ; Aspartame ; Sweetening Agents ; Case-Control Studies ; Autistic Disorder ; Diet
    Chemical Substances Aspartame (Z0H242BBR1) ; Sweetening Agents
    Language English
    Publishing date 2024-02-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu16050675
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Trends in Loss-Adjusted Availability of Added Sugars and Energy Contribution from Macronutrients and Major Food Groups in Canada and the United States

    Wang, Ye (Flora) / Marsden, Sandra / Chiavaroli, Laura / DiAngelo, Chiara / Sievenpiper, John L.

    Journal of the American Nutrition Association. 2023 July 4, v. 42, no. 5, p. 459-468

    2023  , Page(s) 459–468

    Abstract: A clear understanding of changes in the consumption of sugars and other sugars-containing foods has become essential for dietary recommendations and nutrition policy considerations. This study aimed to estimate the consumption trends of added sugars, ... ...

    Abstract A clear understanding of changes in the consumption of sugars and other sugars-containing foods has become essential for dietary recommendations and nutrition policy considerations. This study aimed to estimate the consumption trends of added sugars, energy, macronutrients, and food categories using food supply data. Annual food availability data were obtained from Statistics Canada “Food Available in Canada” database and compared to the equivalent data from Canadian Community Health Survey 2004/2015 and USDA “Food Availability (Per Capita) Data System”. There was a 17% decline in the loss-adjusted per capita consumption of added sugars (%energy) in Canada over the past two decades, largely attributed to reduced intakes of refined sugar and sugars from soft drinks. Added sugars consumption was generally 30% less than that in the US. There was also a consistent decline in total energy intake and %energy from carbohydrates, accompanied by increased %energy derived from fats particularly during the most recent 10 years. The observed trends in added sugars availability are similar to findings from the Canadian Community Health Surveys, demonstrating the potential application of annual loss-adjusted food availability data in monitoring trends in food and macronutrient intakes over time to complement dietary survey data in informing public policy development.
    Keywords USDA ; community health ; databases ; dietary surveys ; energy intake ; food availability ; health surveys ; nutrition policy ; public policy ; refined sugar ; statistics ; Canada ; Sugars ; macronutrients ; per capita consumption ; food availability database
    Language English
    Dates of publication 2023-0704
    Size p. 459-468
    Publishing place Taylor & Francis
    Document type Article ; Online
    ISSN 2769-707X
    DOI 10.1080/07315724.2022.2073923
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Integrating health, nutrition, and environmental impacts of foods: a life cycle impact assessment and modelling analysis of foods in Canada.

    Jarvis, Sarah / Hadjikakou, Michalis / Wu, Jason / Classens, Michael / Chiavaroli, Laura / Sievenpiper, John / L'Abbe, Mary / Jenkins, David / Malik, Vasanti

    The Lancet. Planetary health

    2024  Volume 8 Suppl 1, Page(s) S18

    Abstract: Background: Given the urgency of transitioning towards sustainable nutrition, dietary shifts that provide co-benefits to human health and the environment are imperative. There is currently no database of the environmental impacts of foods that reflects ... ...

    Abstract Background: Given the urgency of transitioning towards sustainable nutrition, dietary shifts that provide co-benefits to human health and the environment are imperative. There is currently no database of the environmental impacts of foods that reflects Canada's unique geographical and agri-climatic context and regional inputs and emissions. To determine sustainable diets, harmonising nutritional considerations with environmental impacts is also essential for an equitable comparison of foods. We aimed to develop a Canadian Food Life Cycle Inventory database and a multidimensional index to enable a joint assessment of the health and environmental impacts of foods in Canada.
    Methods: The Canadian Food Life Cycle Inventory database uses life cycle assessment methodology to evaluate environmental impacts. The datasets mirror Canada's food consumption patterns, averaging the spectrum of agricultural practices weighted by domestic production and import shares. The database is structured according to the nomenclature and categorisation of the Canadian Nutrient File. Environmental sustainability is assessed using a cradle-to-grave approach, including indicators such as greenhouse gas emissions, eutrophication, particulate matter, freshwater usage, land use, non-renewable energy consumption, and food loss and waste. Environmental impacts are quantified through an environmental impact score (EIS) assigned to each impact category for a given food. The EIS-nutrition (EIS-N) integrates the evaluation of nutritional quality with environmental impacts using Nutri-Score, a validated food nutrient-profiling tool. The EIS-N is modelled as a ratio of the EIS to the Nutri-Score values.
    Findings: Preliminary results show the greatest environmental impacts for animal-based foods, particularly beef, in agreement with current literature. Foods with greater nutritional quality also generally show greater environmental sustainability, with some exceptions for particular impact categories.
    Interpretation: The database and index have potential to serve as powerful tools to support researchers, policy makers, and consumers, harnessing big data to drive efficient food and climate solutions for systems transformation.
    Funding: Province of Ontario and University of Toronto, CIHR SMART Healthy Cities Training Platform, and University of Toronto's Temerty Faculty of Medicine.
    MeSH term(s) Animals ; Cattle ; Humans ; Food ; Environment ; Diet ; Life Cycle Stages ; Ontario
    Language English
    Publishing date 2024-04-15
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2542-5196
    ISSN (online) 2542-5196
    DOI 10.1016/S2542-5196(24)00083-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Trends in Loss-Adjusted Availability of Added Sugars and Energy Contribution from Macronutrients and Major Food Groups in Canada and the United States.

    Wang, Ye Flora / Marsden, Sandra / Chiavaroli, Laura / DiAngelo, Chiara / Sievenpiper, John L

    Journal of the American Nutrition Association

    2022  Volume 42, Issue 5, Page(s) 459–468

    Abstract: A clear understanding of changes in the consumption of sugars and other sugars-containing foods has become essential for dietary recommendations and nutrition policy considerations. This study aimed to estimate the consumption trends of added sugars, ... ...

    Abstract A clear understanding of changes in the consumption of sugars and other sugars-containing foods has become essential for dietary recommendations and nutrition policy considerations. This study aimed to estimate the consumption trends of added sugars, energy, macronutrients, and food categories using food supply data.
    Annual food availability data were obtained from Statistics Canada "Food Available in Canada" database and compared to the equivalent data from Canadian Community Health Survey 2004/2015 and USDA "Food Availability (Per Capita) Data System".
    There was a 17% decline in the loss-adjusted
    The observed trends in added sugars availability are similar to findings from the Canadian Community Health Surveys, demonstrating the potential application of annual loss-adjusted food availability data in monitoring trends in food and macronutrient intakes over time to complement dietary survey data in informing public policy development.
    MeSH term(s) United States ; Sugars ; Canada ; Nutrition Surveys ; Energy Intake ; Nutrients ; Carbohydrates
    Chemical Substances Sugars ; Carbohydrates
    Language English
    Publishing date 2022-06-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2769-707X
    ISSN (online) 2769-707X
    DOI 10.1080/07315724.2022.2073923
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Relation of fruit juice with adiposity and diabetes depends on how fruit juice is defined: a re-analysis of the EFSA draft scientific opinion on the tolerable upper intake level for dietary sugars.

    Chen, Victoria / Khan, Tauseef A / Chiavaroli, Laura / Ahmed, Amna / Lee, Danielle / Kendall, Cyril W C / Sievenpiper, John L

    European journal of clinical nutrition

    2023  Volume 77, Issue 7, Page(s) 699–704

    MeSH term(s) Humans ; Adiposity ; Beverages ; Diabetes Mellitus ; Diet ; Dietary Sugars/adverse effects ; Fruit ; Fruit and Vegetable Juices ; Obesity
    Chemical Substances Dietary Sugars
    Language English
    Publishing date 2023-02-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 639358-5
    ISSN 1476-5640 ; 0954-3007
    ISSN (online) 1476-5640
    ISSN 0954-3007
    DOI 10.1038/s41430-023-01258-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Response to comment on "Relation of fruit juice with adiposity and diabetes depends on how fruit juice is defined: a re-analysis of the EFSA draft scientific opinion on the tolerable upper intake level for dietary sugars" by Chen et al. 2023.

    Chen, Victoria / Khan, Tauseef A / Chiavaroli, Laura / Ahmed, Amna / Lee, Danielle / Kendall, Cyril W C / Sievenpiper, John L

    European journal of clinical nutrition

    2023  Volume 77, Issue 12, Page(s) 1178–1179

    MeSH term(s) Humans ; Adiposity ; Fruit and Vegetable Juices ; Dietary Sugars/adverse effects ; Obesity ; Diabetes Mellitus
    Chemical Substances Dietary Sugars
    Language English
    Publishing date 2023-10-18
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 639358-5
    ISSN 1476-5640 ; 0954-3007
    ISSN (online) 1476-5640
    ISSN 0954-3007
    DOI 10.1038/s41430-023-01323-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: WHO guideline on the use of non-sugar sweeteners: a need for reconsideration.

    Khan, Tauseef A / Lee, Jennifer J / Ayoub-Charette, Sabrina / Noronha, Jarvis Clyde / McGlynn, Nema / Chiavaroli, Laura / Sievenpiper, John L

    European journal of clinical nutrition

    2023  Volume 77, Issue 11, Page(s) 1009–1013

    MeSH term(s) Humans ; Sweetening Agents/adverse effects ; Obesity ; World Health Organization ; Non-Nutritive Sweeteners
    Chemical Substances Sweetening Agents ; Non-Nutritive Sweeteners
    Language English
    Publishing date 2023-09-18
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 639358-5
    ISSN 1476-5640 ; 0954-3007
    ISSN (online) 1476-5640
    ISSN 0954-3007
    DOI 10.1038/s41430-023-01314-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Consumption of 100% Fruit Juice and Body Weight in Children and Adults: A Systematic Review and Meta-Analysis.

    Nguyen, Michelle / Jarvis, Sarah E / Chiavaroli, Laura / Mejia, Sonia Blanco / Zurbau, Andreea / Khan, Tauseef A / Tobias, Deirdre K / Willett, Walter C / Hu, Frank B / Hanley, Anthony J / Birken, Catherine S / Sievenpiper, John L / Malik, Vasanti S

    JAMA pediatrics

    2024  Volume 178, Issue 3, Page(s) 237–246

    Abstract: Importance: Concerns have been raised that frequent consumption of 100% fruit juice may promote weight gain. Current evidence on fruit juice and weight gain has yielded mixed findings from both observational studies and clinical trials.: Objective: ... ...

    Abstract Importance: Concerns have been raised that frequent consumption of 100% fruit juice may promote weight gain. Current evidence on fruit juice and weight gain has yielded mixed findings from both observational studies and clinical trials.
    Objective: To synthesize the available evidence on 100% fruit juice consumption and body weight in children and adults.
    Data sources: MEDLINE, Embase, and Cochrane databases were searched through May 18, 2023.
    Study selection: Prospective cohort studies of at least 6 months and randomized clinical trials (RCTs) of at least 2 weeks assessing the association of 100% fruit juice with body weight change in children and adults were included. In the trials, fruit juices were compared with noncaloric controls.
    Data extraction and synthesis: Data were pooled using random-effects models and presented as β coefficients with 95% CIs for cohort studies and mean differences (MDs) with 95% CIs for RCTs.
    Main outcomes and measures: Change in body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) was assessed in children and change in body weight in adults.
    Results: A total of 42 eligible studies were included in this analysis, including 17 among children (17 cohorts; 0 RCTs; 45 851 children; median [IQR] age, 8 [1-15] years) and 25 among adults (6 cohorts; 19 RCTs; 268 095 adults; median [IQR] age among cohort studies, 48 [41-61] years; median [IQR] age among RCTs, 42 [25-59]). Among cohort studies in children, each additional serving per day of 100% fruit juice was associated with a 0.03 (95% CI, 0.01-0.05) higher BMI change. Among cohort studies in adults, studies that did not adjust for energy showed greater body weight gain (0.21 kg; 95% CI, 0.15-0.27 kg) than studies that did adjust for energy intake (-0.08 kg; 95% CI, -0.11 to -0.05 kg; P for meta-regression <.001). RCTs in adults found no significant association of assignment to 100% fruit juice with body weight but the CI was wide (MD, -0.53 kg; 95% CI, -1.55 to 0.48 kg).
    Conclusion and relevance: Based on the available evidence from prospective cohort studies, in this systematic review and meta-analysis, 1 serving per day of 100% fruit juice was associated with BMI gain among children. Findings in adults found a significant association among studies unadjusted for total energy, suggesting potential mediation by calories. Further trials of 100% fruit juice and body weight are desirable. Our findings support guidance to limit consumption of fruit juice to prevent intake of excess calories and weight gain.
    MeSH term(s) Adolescent ; Adult ; Child ; Child, Preschool ; Humans ; Infant ; Middle Aged ; Body Mass Index ; Body Weight ; Fruit and Vegetable Juices ; Randomized Controlled Trials as Topic ; Weight Gain
    Language English
    Publishing date 2024-01-16
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2701223-2
    ISSN 2168-6211 ; 2168-6203
    ISSN (online) 2168-6211
    ISSN 2168-6203
    DOI 10.1001/jamapediatrics.2023.6124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Intakes of nutrients and food categories in Canadian children and adolescents across levels of sugars intake: cross-sectional analyses of the Canadian Community Health Survey 2015 Public Use Microdata File

    Chiavaroli, Laura / Wang, Ye (Flora) / Ahmed, Mavra / Ng, Alena (Praneet) / DiAngelo, Chiara / Marsden, Sandra / Sievenpiper, John L.

    Applied physiology, nutrition and metabolism. 2022, v. 47, no. 4

    2022  

    Abstract: Dietary recommendations to reduce sugars consumption may influence choices of sugars-containing foods and affect the intake of key micronutrients. We compared intakes of nutrients and food sources stratified by quintiles of total sugars in Canadian ... ...

    Abstract Dietary recommendations to reduce sugars consumption may influence choices of sugars-containing foods and affect the intake of key micronutrients. We compared intakes of nutrients and food sources stratified by quintiles of total sugars in Canadian children (2–8 y) and adolescents (9–13 y, 14–18 y) using 24-hour dietary recalls from the 2015 Canadian Community Health Survey-Nutrition. Energy intakes did not differ across quintiles of sugars intake. Those with lower sugars intakes (Q1/Q3) generally had higher protein, fat, sodium, niacin, folate, and zinc and lower vitamin C compared with those with the highest sugars intakes (Q5). Q1 also had lower potassium but higher saturated fat compared with Q5. Further, Q1 generally had higher protein, fats, and niacin compared with Q3, while children in Q3 had higher potassium and riboflavin and older adolescents had higher calcium and fibre. Q5 had highest intakes of multiple sugar-containing food categories (e.g., fruit, confectionary, milks, cakes/pies/pastries), with higher sugars-sweetened beverages in adolescents. Q3 had higher fruit, milks, and fruit juice compared with Q1 and lower sugars/syrups/preserves, confectionary, and fruit juices compared with Q5. Certain nutrient-dense food sources of sugars (fruit, milks) may help increase key nutrients (potassium, calcium, fibre) in older adolescents with low sugars intakes. However, in those with the highest sugars intakes, nutrient-poor foods may displace nutrient-dense foods. Novelty: Canadian children and adolescents with lower sugars intake have better intakes of some nutrients. Energy intakes did not differ across sugars intake. Older adolescents with mean intakes of total sugars had better intakes of some key nutrients (potassium, calcium, fibre).
    Keywords ascorbic acid ; calcium ; community health ; folic acid ; fruit juices ; fruits ; health surveys ; metabolism ; niacin ; potassium ; riboflavin ; saturated fats ; sodium ; sweets ; zinc
    Language English
    Size p. 415-428.
    Publishing place Canadian Science Publishing
    Document type Article
    ZDB-ID 2236708-1
    ISSN 1715-5320 ; 1715-5312
    ISSN (online) 1715-5320
    ISSN 1715-5312
    DOI 10.1139/apnm-2021-0517
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Intakes of nutrients and food categories in Canadian children and adolescents across levels of sugars intake: cross-sectional analyses of the Canadian Community Health Survey 2015 Public Use Microdata File.

    Chiavaroli, Laura / Wang, Ye Flora / Ahmed, Mavra / Ng, Alena Praneet / DiAngelo, Chiara / Marsden, Sandra / Sievenpiper, John L

    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme

    2022  Volume 47, Issue 4, Page(s) 415–428

    Abstract: Dietary recommendations to reduce sugars consumption may influence choices of sugars-containing foods and affect the intake of key micronutrients. We compared intakes of nutrients and food sources stratified by quintiles of total sugars in Canadian ... ...

    Abstract Dietary recommendations to reduce sugars consumption may influence choices of sugars-containing foods and affect the intake of key micronutrients. We compared intakes of nutrients and food sources stratified by quintiles of total sugars in Canadian children (2-8 y) and adolescents (9-13 y, 14-18 y) using 24-hour dietary recalls from the 2015 Canadian Community Health Survey-Nutrition. Energy intakes did not differ across quintiles of sugars intake. Those with lower sugars intakes (Q1/Q3) generally had higher protein, fat, sodium, niacin, folate, and zinc and lower vitamin C compared with those with the highest sugars intakes (Q5). Q1 also had lower potassium but higher saturated fat compared with Q5. Further, Q1 generally had higher protein, fats, and niacin compared with Q3, while children in Q3 had higher potassium and riboflavin and older adolescents had higher calcium and fibre. Q5 had highest intakes of multiple sugar-containing food categories (e.g., fruit, confectionary, milks, cakes/pies/pastries), with higher sugars-sweetened beverages in adolescents. Q3 had higher fruit, milks, and fruit juice compared with Q1 and lower sugars/syrups/preserves, confectionary, and fruit juices compared with Q5. Certain nutrient-dense food sources of sugars (fruit, milks) may help increase key nutrients (potassium, calcium, fibre) in older adolescents with low sugars intakes. However, in those with the highest sugars intakes, nutrient-poor foods may displace nutrient-dense foods.
    MeSH term(s) Adolescent ; Canada ; Child ; Cross-Sectional Studies ; Diet ; Energy Intake ; Humans ; Nutrients/analysis ; Nutrition Surveys ; Public Health ; Sugars
    Chemical Substances Sugars
    Language English
    Publishing date 2022-01-10
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2236708-1
    ISSN 1715-5320 ; 1715-5312
    ISSN (online) 1715-5320
    ISSN 1715-5312
    DOI 10.1139/apnm-2021-0517
    Database MEDical Literature Analysis and Retrieval System OnLINE

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