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  1. AU="Chiba, Kentaro"
  2. AU="Zhou, Jihua"
  3. AU="Ronald Bartels"
  4. AU="Liñares, J"
  5. AU="Valle, Valentina"
  6. AU="Tóth, András"
  7. AU="Pawar, Atul Darasing"
  8. AU="Semper, Chelsea"
  9. AU="Kraus, Joanne F"

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  1. Artikel ; Online: Helmet therapy efficacy and its prediction in Japanese infants with positional plagio- and brachycephaly.

    Aihara, Yasuo / Chiba, Kentaro / Kawamata, Takakazu

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

    2024  

    Abstract: Purpose: To provide additional information on optimal start times and therapeutic effectiveness based on treatment outcome of Japanese infants with positional plagio- and brachycephaly (PPB) receiving cranial molding helmet therapy (CMHT).: Methods: ... ...

    Abstract Purpose: To provide additional information on optimal start times and therapeutic effectiveness based on treatment outcome of Japanese infants with positional plagio- and brachycephaly (PPB) receiving cranial molding helmet therapy (CMHT).
    Methods: In this retrospective cohort study, data from a 3D head scanning system was analyzed from 2173 Japanese infants who completed CMHT. Anterior and posterior symmetry ratio (ASR and PSR) and longitudinal to transverse diagonal ratios (LD/TDR) were calculated based on skull shape at helmet design and at completion of therapy. The outcomes were evaluated using the regression analysis and a predictive model using cranial parameters was developed.
    Results: The earlier the start of therapy, the greater the therapeutic effect on ASR, PSR, and LD/TDR (ASR, -0.134 percent points (ppt)/day; PSR, -0.086 ppt/day; and LD/TDR, -0.131 ppt/day). In the predictive model, in addition to starting age of the therapy, sex (male), the degree of deformity of the head (DoD) (moderate and severe), quadrant volume, PSR, and head circumference at the start of treatment also had a positive effect on changes in ASR, DoD (moderate and severe), ASR, LD/TDR and transverse diameter for PSR, sex (male), DoD (moderate), quadrant volume, PSR, and head circumference for LD/TDR.
    Conclusion: The starting age of therapy had a relatively smaller contribution to outcome effects. Applying the cranial parameter obtained at the start of treatment to the predictive model helps to predict the effect of CMHT and whether PPB can be treated with CMHT in infants of older age.
    Sprache Englisch
    Erscheinungsdatum 2024-03-27
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 605988-0
    ISSN 1433-0350 ; 0302-2803 ; 0256-7040
    ISSN (online) 1433-0350
    ISSN 0302-2803 ; 0256-7040
    DOI 10.1007/s00381-024-06370-3
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  2. Artikel ; Online: A case of a pineal parenchymal tumor of intermediate differentiation with bifocal lesions differentiated by negative placental alkaline phosphatase in the spinal fluid.

    Ito, Koki / Aihara, Yasuo / Chiba, Kentaro / Oda, Yuichi / Kawamata, Takakazu

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

    2024  

    Abstract: Placental alkaline phosphatase (PLAP) in the spinal fluid is helpful for the diagnosis of intracranial germinomas. Bifocal lesions involving the pineal and pituitary regions have also been reported as characteristic findings of intracranial germinomas. ... ...

    Abstract Placental alkaline phosphatase (PLAP) in the spinal fluid is helpful for the diagnosis of intracranial germinomas. Bifocal lesions involving the pineal and pituitary regions have also been reported as characteristic findings of intracranial germinomas. We present a rare case of a 15-year-old boy with a pineal parenchymal tumor of intermediate differentiation (PPTID) with bifocal lesions negative for PLAP. Magnetic resonance imaging of the brain revealed bifocal mass lesions in the pineal and suprasellar regions and non-communicating hydrocephalus. We initially suspected a germinoma based on imaging findings, but all tumor markers, including PLAP, in the spinal fluid were negative. Based on these results, germinoma was considered less likely, and an endoscopic third ventriculostomy and endoscopic tumor biopsy were performed for diagnosis. The histopathological diagnosis was PPTID, corresponding to World Health Organization grade 3, in both pineal and suprasellar specimens. A craniotomy for tumor removal was performed, resulting in total resection. PLAP is known to have high sensitivity and extremely high negative predictive value for germinomas. Although bifocal lesions highly suggest germ cell tumors, there are exceptions, as in the present case. This case suggests that PLAP measurements are useful for differentiation, leading to appropriate treatment strategies.
    Sprache Englisch
    Erscheinungsdatum 2024-05-07
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 605988-0
    ISSN 1433-0350 ; 0302-2803 ; 0256-7040
    ISSN (online) 1433-0350
    ISSN 0302-2803 ; 0256-7040
    DOI 10.1007/s00381-024-06429-1
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  3. Artikel ; Online: Selective surgical mamillo-thalamic tract disconnection in hypothalamic hamartoma results in complete disappearance of gelastic seizures.

    Eguchi, Seiichiro / Aihara, Yasuo / Chiba, Kentaro / Kawamata, Takakazu

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

    2023  Band 39, Heft 5, Seite(n) 1303–1307

    Abstract: Hypothalamic hamartoma is a less common condition characterized by the several types of epileptic seizures including the gelastic type. It is reported that gelastic seizures are resistant to medical treatment with anticonvulsants, while stereotactic ... ...

    Abstract Hypothalamic hamartoma is a less common condition characterized by the several types of epileptic seizures including the gelastic type. It is reported that gelastic seizures are resistant to medical treatment with anticonvulsants, while stereotactic thermocoagulation or Gamma Knife radiosurgery are effective for seizure control. Here, we report an individual case where direct surgical resection disconnecting hypothalamic hamartoma from mammillothalamic tract resulted in complete disappearance of gelastic seizures without deterioration of cognitive function. A 6-year-old boy developed gelastic seizures at the age of 2 and suffered from precocious puberty. Anticonvulsants including carbamazepine and zonisamide failed to control seizures. The patient underwent direct division of the mammillothalmic tract by removal of hypothalamic hamartoma partially via anterior interhemispheric approach. It was observed that gelastic seizures disappeared completely after the surgical treatment without any endocrine and cognitive dysfunction for a follow-up period of 14 years. The mammillothalamic tract which connects anterior nucleus of thalamus and mammillary bodies plays a key role in gelastic seizures related to hypothalamic hamartoma. In this case, we disconnected the hamartoma specifically from the mammillary bodies and not from the rest of hypothalamus. Effectively, it enabled permanent control of seizures. This result shows that fibers connecting other hypothalamic structures and the dorsomedial nucleus of thalamus are not involved in gelastic seizure propagation from the hypothalamic hamartoma. When surgical treatment of hypothalamic hamartomas is performed it has high morbidity associated with hypothalamic disorders. Therefore, disconnection between hypothalamic hamartoma and mammillary bodies presents a possibility of reducing hypothalamic damage. Surgical disconnection between hamartoma and mammillothalamic tract carries minimal hypothalamic injury risk and our results suggest that it has the potential of seizure control for intractable gelastic seizures with less complications.
    Mesh-Begriff(e) Male ; Humans ; Child ; Anticonvulsants ; Magnetic Resonance Imaging/adverse effects ; Hypothalamic Diseases/complications ; Hypothalamic Diseases/surgery ; Epilepsies, Partial/surgery ; Epilepsies, Partial/complications ; Hamartoma/complications ; Hamartoma/diagnostic imaging ; Hamartoma/surgery ; Seizures/surgery ; Seizures/complications ; Thalamus
    Chemische Substanzen Anticonvulsants
    Sprache Englisch
    Erscheinungsdatum 2023-03-21
    Erscheinungsland Germany
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 605988-0
    ISSN 1433-0350 ; 0302-2803 ; 0256-7040
    ISSN (online) 1433-0350
    ISSN 0302-2803 ; 0256-7040
    DOI 10.1007/s00381-023-05921-4
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  4. Artikel ; Online: Screen-printed wearable skin surface pH sensor for real-time monitoring of the buffering capacity of human skin.

    Chiba, Kentaro / Harada, Yutaro / Matsumoto, Hirotaka / Matsui, Hiroyuki / Ito, Naoya / Sekine, Tomohito / Nagamine, Kuniaki

    Analytical and bioanalytical chemistry

    2024  Band 416, Heft 7, Seite(n) 1635–1645

    Abstract: This study demonstrated for the first time that skin surface pH can be monitored in real-time, using a screen-printed wearable pH sensor, to evaluate the buffering capacity of the human skin. The screen-printed pH sensor was composed of a polyaniline- ... ...

    Abstract This study demonstrated for the first time that skin surface pH can be monitored in real-time, using a screen-printed wearable pH sensor, to evaluate the buffering capacity of the human skin. The screen-printed pH sensor was composed of a polyaniline-based pH-sensitive electrode and a nitrocellulose membrane-based liquid junction type of Ag/AgCl reference electrode. This sensor showed a reliable and reversible potentiometric response to pH with long-term potential stability. Intermittent monitoring of the buffering capacity of skin surface pH demonstrated the reliability of the proposed wearable pH sensor, which was comparable to that of a commercially available flat-tip pH sensor. We found that contact of the wearable pH sensor with the subject's skin via aqueous electrolyte solutions was necessary for the sensor to continuously monitor the skin surface pH while sustaining the natural buffer capacity of the human skin surface.
    Mesh-Begriff(e) Humans ; Reproducibility of Results ; Wearable Electronic Devices ; Skin ; Electrodes ; Hydrogen-Ion Concentration
    Sprache Englisch
    Erscheinungsdatum 2024-01-31
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 201093-8
    ISSN 1618-2650 ; 0016-1152 ; 0372-7920
    ISSN (online) 1618-2650
    ISSN 0016-1152 ; 0372-7920
    DOI 10.1007/s00216-024-05165-4
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  5. Artikel ; Online: Brainstem cavernous hemangioma with improvement of Holmes tremor on excision.

    Eguchi, Hiroki / Aihara, Yasuo / Chiba, Kentaro / Oda, Yuichi / Momozaki, Ouji / Saitou, Ryo / Kawamata, Takakazu

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

    2024  

    Abstract: An 8-year-old boy presenting with left-angle paralysis, tremor in upper and lower extremities, and diplopia was diagnosed with hemorrhage from a mesencephalic cavernous hemangioma. He underwent hemangiomectomy through the occipital transtentorial ... ...

    Abstract An 8-year-old boy presenting with left-angle paralysis, tremor in upper and lower extremities, and diplopia was diagnosed with hemorrhage from a mesencephalic cavernous hemangioma. He underwent hemangiomectomy through the occipital transtentorial approach 4 weeks post-hemorrhage, after which Holmes tremor (HT) markedly reduced. A year later, hemangioma has not recurred; he is now independent in his daily activities. Early intervention in the subacute stage allows for the complete removal of brainstem cavernomas (BSCs), with minimal risk of complications or sequelae. Proper timing and surgical approach for BSCs can prevent re-bleeding and improve HT after an initial hemorrhage, without any lasting negative consequences.
    Sprache Englisch
    Erscheinungsdatum 2024-04-19
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 605988-0
    ISSN 1433-0350 ; 0302-2803 ; 0256-7040
    ISSN (online) 1433-0350
    ISSN 0302-2803 ; 0256-7040
    DOI 10.1007/s00381-024-06423-7
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  6. Artikel: Endoscope-assisted Trans-lamina Terminalis Resection of Chordoid Glioma at the Third Ventricle: A Case Report.

    Oda, Yuichi / Amano, Kosaku / Chiba, Kentaro / Masui, Kenta / Kawamata, Takakazu

    NMC case report journal

    2023  Band 10, Seite(n) 285–289

    Abstract: As per the 2021 World Health Organization (WHO) Classification of Tumors of the Central Nervous System, chordoid glioma (CG) is defined as a slow-growing glial neoplasm categorized as grade II tumor. This tumor is primarily located in the anterior part ... ...

    Abstract As per the 2021 World Health Organization (WHO) Classification of Tumors of the Central Nervous System, chordoid glioma (CG) is defined as a slow-growing glial neoplasm categorized as grade II tumor. This tumor is primarily located in the anterior part of the third ventricle, often adheres to important surrounding structures, and is hemorrhagic in nature. Therefore, dissecting this tumor is extremely difficult. In this study, we present the case of a 44-year-old man who initially complained of mild headache and was diagnosed with a homogeneous gadolinium-enhanced lesion in the third ventricle via magnetic resonance imaging. The pathological diagnosis based on his biopsy at the previous hospital was CG. The patient demonstrated no neurological deficit at that time, but the tumor had gradually grown, hydrocephalus appeared 2 years after the tumor was detected, and the patient developed short memory disorder and daytime sleepiness. We resected the tumor via the anterior interhemispheric trans-lamina terminalis approach using a microscope and an endoscope. The residual tumor at the blind spot of the microscopic view was resected under an angled rigid endoscopic view using dedicated tools for transsphenoidal surgery. The tumor was grossly resected, and the histopathological diagnosis was CG. Postoperative neurological findings included slight memory disorder and hypothalamic adrenal dysfunction. No tumor recurrence was reported 3 years post resection. The endoscope-assisted anterior interhemispheric trans-lamina terminalis approach was determined useful for CG resection with minimal surgical complications and without tumor recurrence.
    Sprache Englisch
    Erscheinungsdatum 2023-10-14
    Erscheinungsland Japan
    Dokumenttyp Case Reports
    ISSN 2188-4226
    ISSN 2188-4226
    DOI 10.2176/jns-nmc.2023-0107
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  7. Artikel ; Online: One-Piece Frontoorbital Osteotomy With a Small Supraorbital Burr-Hole to Protect Against Intraoperative Dural Lacerations.

    Hasegawa, Yuki / Aihara, Yasuo / Chiba, Kentaro / Sakurai, Hiroyuki

    The Journal of craniofacial surgery

    2022  Band 33, Heft 6, Seite(n) 1883–1884

    Abstract: Abstract: This paper aims to describe a new technique of 1-piece frontoorbital osteotomy with a small supraorbital burr hole, which resulted in improved safety during osteotomy of the anterior skull base. An 11 × 4 mm burr hole was created at the center ...

    Abstract Abstract: This paper aims to describe a new technique of 1-piece frontoorbital osteotomy with a small supraorbital burr hole, which resulted in improved safety during osteotomy of the anterior skull base. An 11 × 4 mm burr hole was created at the center of the orbit above the superior orbital rim using an "eyebrow key-window approach." Extradural dissection from the nasion to the medial side of the sphenoid ridge was performed through this hole, and dissection of the lateral side of the sphenoid ridge was completed from the edge of the coronal osteotomy. Osteotomy along the zygomaticofrontal and sphenofrontal sutures were performed using an oscillating saw with secure protection of the dura. Between December 2019 and June 2020, 3 patients with unilateral coronal craniosynostosis underwent 1-piece frontoorbital advancement with the eyebrow key-window approach. The median age was 11 months (8-15 months), median operation time was 249 minutes (244-255 minutes), and the average blood transfusion was 10.8 ml/kg (0-18 ml/kg). No complications were observed, and the technique was associated with improved safety of osteotomy around the anterior skull base for 1-piece frontoorbital advancement.
    Mesh-Begriff(e) Cranial Sutures/surgery ; Craniosynostoses/surgery ; Craniotomy/methods ; Humans ; Infant ; Lacerations/surgery ; Orbit/surgery ; Osteotomy/methods
    Sprache Englisch
    Erscheinungsdatum 2022-06-29
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000008499
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  8. Artikel: Systemic Metastasis of Pediatric Diffuse High-grade Astrocytoma: A Case Report.

    Chiba, Kentaro / Aihara, Yasuo / Oda, Yuichi / Masui, Kenta / Komori, Takashi / Yokoo, Hideaki / Kawamata, Takakazu

    NMC case report journal

    2023  Band 10, Seite(n) 265–271

    Abstract: Extracranial brain tumor metastases are extremely rare. The etiology, pathophysiology, and clinical progression of systemic metastatic brain cancer remain to be elucidated. We encountered a case of pediatric diffuse high-grade astrocytoma in a four-year- ... ...

    Abstract Extracranial brain tumor metastases are extremely rare. The etiology, pathophysiology, and clinical progression of systemic metastatic brain cancer remain to be elucidated. We encountered a case of pediatric diffuse high-grade astrocytoma in a four-year-old girl with subcutaneous and lymph node metastases. Numerous metastatic lesions emerged, progressed rapidly, and were difficult to manage despite temozolomide (TMZ) administration. The patient underwent repeated surgical resection for these lesions. Conversely, the primary intracranial lesions responded well to TMZ for some time. However, the patient died 15 months after the initial diagnosis. Extracranial metastasis and highly varying effects of chemotherapy were the characteristic clinical features in this case. Our analysis did not reveal definitive histopathological and molecular factors contributing to this presentation. The lack of notable molecular pathological features illustrates the unpredictability of glioma metastasis, and the treatment for extracranial metastasis remains unknown. A gene panel analysis revealed several genetic aberrations, including
    Sprache Englisch
    Erscheinungsdatum 2023-10-14
    Erscheinungsland Japan
    Dokumenttyp Case Reports
    ISSN 2188-4226
    ISSN 2188-4226
    DOI 10.2176/jns-nmc.2023-0018
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  9. Artikel ; Online: Efficacy of the pedicle trapezius muscle flap for the multisurgical removal of pediatric posterior fossa anaplastic ependymoma.

    Nakamura, Akikazu / Aihara, Yasuo / Chiba, Kentaro / Matsumine, Hajime / Sakurai, Hiroyuki / Kawamata, Takakazu

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

    2023  Band 39, Heft 6, Seite(n) 1635–1639

    Abstract: Objective: Exceedingly refractory, pediatric anaplastic ependymoma in many cases requires multisurgical removal. The high risk of poor wound healing and CSF leakage especially at the posterior fossa make this tumor difficult to treat.: Case: A 9-year- ...

    Abstract Objective: Exceedingly refractory, pediatric anaplastic ependymoma in many cases requires multisurgical removal. The high risk of poor wound healing and CSF leakage especially at the posterior fossa make this tumor difficult to treat.
    Case: A 9-year-old girl has had 4th ventricular anaplastic ependymoma since the age of 3. She experienced tumor removal 8 times including 4 posterior fossa craniotomies because tumors were disseminated not only to the posterior fossa but also to the cerebral hemispheres. She also underwent a dermal graft using a free flap. She experienced CSF leaks and meningitis frequently because the wound healing was poor. We performed a dermal flap closure using a pedicle trapezius muscle flap with a plastic surgeon when we performed the 5th tumor removal.
    Result: We achieved complete wound closure in spite of broad deficiencies in subcutaneous and epidermal tissues. After that, recurrences of posterior fossa tumors presented within a short term, and tumor removal via an incision of a pedicle trapezius muscle flap was performed without recurrence of CSF leaks and meningitis.
    Discussion and conclusion: For the first time, we are able to report on the efficacy of using the pedicle trapezius muscle flap for multisurgical removal of pediatric posterior fossa anaplastic ependymoma. The muscle flap was found to be effective because of the multiple surgeries expected, and the pedicle trapezius muscle flap was found to be resilient to multiple surgical procedures. Although advantageous, the dorsal scapular artery which is required for flap creation is actually difficult to harvest. Compared to a flee flap, the pedicle trapezius muscle flap maintains vascular supply. Furthermore, this technique has the possibility of being applied to defective dura mater closure that cannot be watertight due to multiple surgeries. However, it is very important to inform the patient's family not only about the improved efficacy of surgery, but also to raise awareness on consequential cosmetic issues.
    Mesh-Begriff(e) Female ; Humans ; Child ; Superficial Back Muscles/blood supply ; Superficial Back Muscles/transplantation ; Surgical Flaps ; Plastic Surgery Procedures ; Meningitis ; Ependymoma/surgery
    Sprache Englisch
    Erscheinungsdatum 2023-04-05
    Erscheinungsland Germany
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 605988-0
    ISSN 1433-0350 ; 0302-2803 ; 0256-7040
    ISSN (online) 1433-0350
    ISSN 0302-2803 ; 0256-7040
    DOI 10.1007/s00381-023-05941-0
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  10. Artikel ; Online: Breath-holding spells after endoscopic third ventriculostomy in a post-ventriculoperitoneal shunted patient.

    Chiba, Kentaro / Aihara, Yasuo / Kawamata, Takakazu

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

    2021  Band 38, Heft 4, Seite(n) 813–816

    Abstract: Breath-holding spells (BHS) are commonly observed in children as a result of an autonomic nervous system disorder triggered by crying, emotional distress, or pain. There are several types of BHS and cyanotic type is one of them. We encountered a case of ... ...

    Abstract Breath-holding spells (BHS) are commonly observed in children as a result of an autonomic nervous system disorder triggered by crying, emotional distress, or pain. There are several types of BHS and cyanotic type is one of them. We encountered a case of 3-year-old girl who presented with a delayed adaptation period and BHS 2 weeks after an endoscopic third ventriculostomy (ETV). She experienced severe headache due to increased intracranial pressure (ICP) during the delayed adaptation period, which may have contributed to the onset of BHS. Management of BHS warrants treatment of the symptoms and removal of the causative factors; in our case, intensive pain control and resolution of the increased ICP after the adaptation period were effective. While BHS are usually described as a benign condition that improves spontaneously, we highlighted the importance of recognizing and monitoring atypical symptoms such as BHS in pediatric cases.
    Mesh-Begriff(e) Autonomic Nervous System Diseases/complications ; Breath Holding ; Child ; Child, Preschool ; Cyanosis ; Female ; Humans ; Infant ; Ventriculoperitoneal Shunt/adverse effects ; Ventriculostomy/adverse effects
    Sprache Englisch
    Erscheinungsdatum 2021-07-02
    Erscheinungsland Germany
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 605988-0
    ISSN 1433-0350 ; 0302-2803 ; 0256-7040
    ISSN (online) 1433-0350
    ISSN 0302-2803 ; 0256-7040
    DOI 10.1007/s00381-021-05247-z
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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