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  1. Article ; Online: In Reference to Gastroesophageal Reflux and Chronic Rhinosinusitis: A Mendelian Randomization Study.

    Maniaci, Antonino / Iannella, Giannicola / Chiesa-Estomba, Carlos M / Saibene, Alberto M / Lechien, Jerome R

    The Laryngoscope

    2024  

    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Letter
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.31354
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  2. Article ; Online: Accuracy of ChatGPT in head and neck oncological board decisions: preliminary findings.

    Lechien, Jerome R / Chiesa-Estomba, Carlos-Miguel / Baudouin, Robin / Hans, Stéphane

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2023  Volume 281, Issue 4, Page(s) 2105–2114

    Abstract: Objectives: To evaluate the ChatGPT-4 performance in oncological board decisions.: Methods: Twenty medical records of patients with head and neck cancer were evaluated by ChatGPT-4 for additional examinations, management, and therapeutic approaches. ... ...

    Abstract Objectives: To evaluate the ChatGPT-4 performance in oncological board decisions.
    Methods: Twenty medical records of patients with head and neck cancer were evaluated by ChatGPT-4 for additional examinations, management, and therapeutic approaches. The ChatGPT-4 propositions were assessed with the Artificial Intelligence Performance Instrument. The stability of ChatGPT-4 was evaluated through regenerated answers at 1-day interval.
    Results: ChatGPT-4 provided adequate explanations for cTNM staging in 19 cases (95%). ChatGPT-4 proposed a significant higher number of additional examinations than practitioners (72 versus 103; p = 0.001). ChatGPT-4 indications of endoscopy-biopsy, HPV research, ultrasonography, and PET-CT were consistent with the oncological board decisions. The therapeutic propositions of ChatGPT-4 were accurate in 13 cases (65%). Most additional examination and primary treatment propositions were consistent throughout regenerated response process.
    Conclusions: ChatGPT-4 may be an adjunctive theoretical tool in oncological board simple decisions.
    MeSH term(s) Humans ; Artificial Intelligence ; Positron Emission Tomography Computed Tomography ; Head ; Neck ; Biopsy
    Language English
    Publishing date 2023-11-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-023-08326-w
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  3. Article ; Online: Laryngeal verrucous cell carcinoma.

    Lechien, Jerome R / Vaira, Luigi A / Chiesa-Estomba, Carlos M

    Current opinion in otolaryngology & head and neck surgery

    2023  Volume 32, Issue 2, Page(s) 118–124

    Abstract: Purpose of review: To summarize the recent literature on epidemiology, clinical findings, treatment, and survival of laryngeal verrucous cell carcinoma (LVC).: Recent findings: Epidemiological studies report that LVC accounts for 1-3% of all ... ...

    Abstract Purpose of review: To summarize the recent literature on epidemiology, clinical findings, treatment, and survival of laryngeal verrucous cell carcinoma (LVC).
    Recent findings: Epidemiological studies report that LVC accounts for 1-3% of all laryngeal cancers. The incidence is decreasing, while most patients are male individuals and smokers. LVC are commonly detected in early stages because they are more frequently located in the glottic region. Tobacco, alcohol overuse, and, possibly, human papilloma virus are the main contributing factors. Recent studies confirm that surgery is the primary therapeutic approach with better prognosis when compared with other treatment modalities. Surgery alone is associated with 86.8% disease-free and 80.3% overall survival rates, while metastases are anecdotal.
    Summary: LVC presents different clinical, pathological, and survival outcomes when compared with the classic laryngeal squamous cell carcinoma. Biopsies need often to be repeated before getting the most appropriate diagnosis; this supports the need of large-sample biopsy during the tumor diagnosis and staging. The glottic location of most LVC leads to detection of this lesion in its early stages, with ensuing better survival and outcomes after surgery compared with the classic form of squamous cell carcinoma. Future studies are needed to understand the biology of LVC and its related better prognostic outcomes when compared to other laryngeal malignancies.
    MeSH term(s) Humans ; Male ; Female ; Squamous Cell Carcinoma of Head and Neck/pathology ; Carcinoma, Squamous Cell/pathology ; Prognosis ; Larynx ; Laryngeal Neoplasms/diagnosis ; Laryngeal Neoplasms/epidemiology ; Laryngeal Neoplasms/surgery ; Head and Neck Neoplasms/pathology ; Neoplasm Staging
    Language English
    Publishing date 2023-10-10
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1232518-1
    ISSN 1531-6998 ; 1068-9508
    ISSN (online) 1531-6998
    ISSN 1068-9508
    DOI 10.1097/MOO.0000000000000910
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  4. Article ; Online: Performance and Consistency of ChatGPT-4 Versus Otolaryngologists: A Clinical Case Series.

    Lechien, Jérôme R / Naunheim, Mattheuw R / Maniaci, Antonino / Radulesco, Thomas / Saibene, Alberto M / Chiesa-Estomba, Carlos M / Vaira, Luigi A

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

    2024  

    Abstract: Objective: To study the performance of Chatbot Generative Pretrained Transformer-4 (ChatGPT-4) in the management of cases in otolaryngology-head and neck surgery.: Study design: Prospective case series.: Setting: Multicenter University Hospitals.!# ...

    Abstract Objective: To study the performance of Chatbot Generative Pretrained Transformer-4 (ChatGPT-4) in the management of cases in otolaryngology-head and neck surgery.
    Study design: Prospective case series.
    Setting: Multicenter University Hospitals.
    Methods: History, clinical, physical, and additional examinations of adult outpatients consulting in otolaryngology departments of CHU Saint-Pierre and Dour Medical Center were presented to ChatGPT-4, which was interrogated for differential diagnoses, management, and treatment(s). According to specialty, the ChatGPT-4 responses were assessed by 2 distinct, blinded board-certified otolaryngologists with the Artificial Intelligence Performance Instrument.
    Results: One hundred cases were presented to ChatGPT-4. ChaGPT-4 indicated a mean of 3.34 (95% confidence interval [CI]: 3.09, 3.59) additional examinations per patient versus 2.10 (95% CI: 1.76, 2.34; P = .001) for the practitioners. There was strong consistency (k > 0.600) between otolaryngologists and ChatGPT-4 for the indication of upper aerodigestive tract endoscopy, positron emission tomography and computed tomography, audiometry, tympanometry, and psychophysical evaluations. Primary diagnosis was correctly performed by ChatGPT-4 in 38% to 86% of cases depending on subspecialty. Additional examinations indicated by ChatGPT-4 were pertinent and necessary in 8% to 31% of cases, while the treatment regimen was pertinent in 12% to 44% of cases. The performance of ChatGPT-4 was not influenced by the human-reported level of difficulty of clinical cases.
    Conclusion: ChatGPT-4 may be a promising adjunctive tool in otolaryngology, providing extensive documentation about additional examinations, primary and differential diagnoses, and treatments. The ChatGPT-4 is more effective in providing a primary diagnosis, and less effective in the selection of additional examinations and treatments.
    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 392085-9
    ISSN 1097-6817 ; 0161-6439 ; 0194-5998
    ISSN (online) 1097-6817
    ISSN 0161-6439 ; 0194-5998
    DOI 10.1002/ohn.759
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  5. Article ; Online: ChatGPT performance in laryngology and head and neck surgery: a clinical case-series.

    Lechien, Jerome R / Georgescu, Bianca M / Hans, Stephane / Chiesa-Estomba, Carlos M

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2023  Volume 281, Issue 1, Page(s) 319–333

    Abstract: Objectives: To study the performance of ChatGPT in the management of laryngology and head and neck (LHN) cases.: Methods: History and clinical examination of patients consulting at the Otolaryngology-Head and Neck Surgery department were presented to ...

    Abstract Objectives: To study the performance of ChatGPT in the management of laryngology and head and neck (LHN) cases.
    Methods: History and clinical examination of patients consulting at the Otolaryngology-Head and Neck Surgery department were presented to ChatGPT, which was interrogated for differential diagnosis, management, and treatment. The ChatGPT performance was assessed by two blinded board-certified otolaryngologists using the following items of a composite score and the Ottawa Clinic Assessment Tool: differential diagnosis; additional examination; and treatment options. The complexity of clinical cases was evaluated with the Amsterdam Clinical Challenge Scale test.
    Results: Forty clinical cases were submitted to ChatGPT, accounting for 14 (35%), 12 (30%), and 14 (35%) easy, moderate and difficult cases, respectively. ChatGPT indicated a significant higher number of additional examinations compared to practitioners (p = 0.001). There was a significant agreement between practitioners and ChatGPT for the indication of some common examinations (audiometry, ultrasonography, biopsy, gastrointestinal endoscopy or videofluoroscopy). ChatGPT never indicated some important additional examinations (PET-CT, voice quality assessment, or impedance-pH monitoring). ChatGPT reported highest performance in the proposition of the primary (90%) or the most plausible differential diagnoses (65%), and the therapeutic options (60-68%). The ChatGPT performance in the indication of additional examinations was lowest.
    Conclusions: ChatGPT is a promising adjunctive tool in LHN practice, providing extensive documentation about disease-related additional examinations, differential diagnoses, and treatments. The ChatGPT is more efficient in diagnosis and treatment, rather than in the selection of the most adequate additional examination.
    MeSH term(s) Humans ; Positron Emission Tomography Computed Tomography ; Otolaryngology ; Otolaryngologists ; Biopsy ; Diagnosis, Differential
    Language English
    Publishing date 2023-10-24
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-023-08282-5
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  6. Article ; Online: Dysphagia after supraglottic laryngeal cancer surgery.

    Lechien, Jerome R / Chiesa-Estomba, Carlos M / Maniaci, Antonino / Vaira, Luigi A / Gengler, Isabelle M

    American journal of otolaryngology

    2023  Volume 44, Issue 4, Page(s) 103925

    MeSH term(s) Humans ; Laryngeal Neoplasms/surgery ; Laryngeal Neoplasms/pathology ; Deglutition Disorders/diagnosis ; Deglutition Disorders/etiology ; Deglutition Disorders/surgery ; Squamous Cell Carcinoma of Head and Neck/surgery ; Carcinoma, Squamous Cell/surgery ; Carcinoma, Squamous Cell/pathology ; Head and Neck Neoplasms/surgery ; Laryngectomy/adverse effects ; Retrospective Studies ; Neoplasm Staging
    Language English
    Publishing date 2023-05-05
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2023.103925
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  7. Article ; Online: La alteración del olfato y el gusto en pacientes COVID-19. Un recurso diagnóstico en atención primaria.

    Chiesa-Estomba, Carlos M / Lechien, Jerome R / Saussez, Sven

    Atencion primaria

    2020  Volume 52, Issue 8, Page(s) 592–593

    Title translation The alteration of smell and taste in COVID-19 patients. A diagnostic resource in primary care.
    MeSH term(s) COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Humans ; Olfaction Disorders/etiology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Primary Health Care ; Taste Disorders/etiology
    Keywords covid19
    Language Spanish
    Publishing date 2020-05-27
    Publishing country Spain
    Document type Letter
    ZDB-ID 1200787-0
    ISSN 1578-1275 ; 0212-6567
    ISSN (online) 1578-1275
    ISSN 0212-6567
    DOI 10.1016/j.aprim.2020.05.005
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  8. Article ; Online: Response to: Reconstruction using facial artery system-based flaps. One vascular system for multiple purposes in head and neck reconstructive surgery.

    Gonzalez-Garcia, Jose A / Chiesa-Estomba, Carlos M

    Acta otorrinolaringologica espanola

    2020  Volume 72, Issue 2, Page(s) 136

    MeSH term(s) Arteries/surgery ; Humans ; Reconstructive Surgical Procedures ; Surgical Flaps
    Language Spanish
    Publishing date 2020-12-30
    Publishing country Spain
    Document type Letter ; Comment
    ISSN 2173-5735
    ISSN (online) 2173-5735
    DOI 10.1016/j.otorri.2020.08.007
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  9. Article ; Online: Vascular Eagle Syndrome, cervical surgical approach video.

    Chiesa-Estomba, C M / Vargas, A / González-García, J A

    European annals of otorhinolaryngology, head and neck diseases

    2021  Volume 138 Suppl 2, Page(s) 61–62

    MeSH term(s) Adult ; Humans ; Male ; Neck ; Ossification, Heterotopic/diagnostic imaging ; Ossification, Heterotopic/surgery ; Temporal Bone/abnormalities ; Temporal Bone/diagnostic imaging ; Temporal Bone/surgery
    Language English
    Publishing date 2021-05-26
    Publishing country France
    Document type Case Reports ; Video-Audio Media
    ZDB-ID 2558008-5
    ISSN 1879-730X ; 1879-7296
    ISSN (online) 1879-730X
    ISSN 1879-7296
    DOI 10.1016/j.anorl.2020.12.015
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  10. Article ; Online: Pathophysiological mechanisms and management of patients with long-time anosmia related to COVID-19.

    Lechien, J R / Chiesa-Estomba, C M / Hans, S / Saussez, S

    Journal of internal medicine

    2021  Volume 290, Issue 2, Page(s) 464–465

    MeSH term(s) Anosmia ; COVID-19 ; Humans ; Olfaction Disorders/etiology ; Olfaction Disorders/therapy ; SARS-CoV-2
    Language English
    Publishing date 2021-02-15
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 96274-0
    ISSN 1365-2796 ; 0954-6820
    ISSN (online) 1365-2796
    ISSN 0954-6820
    DOI 10.1111/joim.13257
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