Article ; Online: Cardiovascular Risk Factor Burden and Association With CKD in Ghana and Nigeria.
Kidney international reports
2022 Volume 8, Issue 3, Page(s) 658–666
Abstract: Introduction: Cardiovascular disease is the leading cause of morbidity and mortality in patients with chronic kidney disease (CKD); however, the burden of cardiovascular risk factors in patients with CKD in Africa is not well characterized. We ... ...
| Abstract | Introduction: Cardiovascular disease is the leading cause of morbidity and mortality in patients with chronic kidney disease (CKD); however, the burden of cardiovascular risk factors in patients with CKD in Africa is not well characterized. We determined the prevalence of selected cardiovascular risk factors, and association with CKD in the Human Heredity for Health in Africa Kidney Disease Research Network study. Methods: We recruited patients with and without CKD in Ghana and Nigeria. CKD was defined as estimated glomerular filtration rate of <60 ml/min per 1.73 m Results: We enrolled 8396 participants (cases with CKD, 3956), with 56% females. The mean age (45.5 ± 15.1 years) did not differ between patients and control group. The prevalence of hypertension (59%), diabetes (20%), and elevated cholesterol (9.9%), was higher in CKD patients than in the control participants ( Conclusion: Cardiovascular risk factors are prevalent in middle-aged adult patients with CKD in Ghana and Nigeria, with higher proportions in Ghana than in Nigeria. Hypertension, elevated cholesterol, and underweight were independently associated with CKD. |
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| Language | English |
| Publishing date | 2022-12-06 |
| Publishing country | United States |
| Document type | Journal Article |
| ISSN | 2468-0249 |
| ISSN (online) | 2468-0249 |
| DOI | 10.1016/j.ekir.2022.11.021 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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