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  1. Book ; Online ; E-Book: Contemporary obstetrics and gynecology for developing countries

    Okonofua, Friday / Balogun, Joseph A. / Odunsi, Kunle / Chilaka, Victor N.

    2021  

    Abstract: Intro -- Foreword -- Preface -- Reviewers -- Acknowledgements -- Contents -- About the Editors -- Contributors -- Part I: Women's Reproductive Health -- 1: Sexual and Reproductive Health and Rights: An Overview -- 1.1 What Is Reproductive Health? -- 1.2 ... ...

    Author's details Friday Okonofua, Joseph A. Balogun, Kunle Odunsi, Victor N. Chilaka editors
    Abstract Intro -- Foreword -- Preface -- Reviewers -- Acknowledgements -- Contents -- About the Editors -- Contributors -- Part I: Women's Reproductive Health -- 1: Sexual and Reproductive Health and Rights: An Overview -- 1.1 What Is Reproductive Health? -- 1.2 Sexual Health -- 1.3 Components of Sexual and Reproductive Health -- 1.4 What Is New About the Concept of Sexual and Reproductive Health? -- 1.5 The Role of Men in Sexual and Reproductive Health -- 1.6 The Concept of Sexual and Reproductive Health and Rights: A Paradigm Shift in Population Activities -- 1.7 Why Is Sexual and Reproductive Health Important? -- References -- 2: Clinical Diagnosis in Obstetrics and Gynaecology -- 2.1 Gynaecological History Taking -- 2.1.1 Introduction -- 2.1.2 History of Presenting Complaint -- 2.1.3 Menstrual History -- 2.1.4 Past Gynaecological History -- 2.1.5 Past Obstetric History -- 2.1.6 Past Medical and Surgical History -- 2.2 The Gynaecological Examination -- 2.2.1 General Physical Examination -- 2.2.2 Examination of the Abdomen -- 2.2.3 Pelvic Examination -- 2.3 Investigations in Gynaecology -- 2.3.1 Urethral, Vaginal and Endocervical Swabs -- 2.3.2 Papanicolaou Test or Pap Smear -- 2.3.3 Uterine Aspiration Cytology -- 2.3.4 Cold Cone Biopsy -- 2.3.5 Culdocentesis -- 2.3.6 Hormone Assay -- 2.3.7 Imaging Techniques -- 2.3.8 Diagnostic Endoscopy -- 2.4 Obstetric History Taking -- 2.4.1 Biodata -- 2.4.2 History of Current Pregnancy -- 2.4.3 Past Obstetric History -- 2.4.4 Gynaecological History -- 2.4.5 Past Medical and Surgical History -- 2.4.6 Drug History and Allergy -- 2.4.7 Family and Social History -- 2.4.8 Systemic Review -- 2.5 Obstetric Examination -- 2.5.1 General Examination -- 2.5.2 Abdominal Examination -- 2.6 Conclusion -- References -- 3: Maternal Mortality in Developing Countries.
    Keywords Electronic books ; Genital Diseases, Female ; Pregnancy Complications ; eproductive Health Services ; Developing Countries
    Language English
    Size 1 Online-Ressource (xxiv, 805 Seiten), Illustrationen
    Edition Second edition
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021025589
    ISBN 978-3-030-75385-6 ; 9783030753849 ; 3-030-75385-9 ; 3030753840
    DOI 10.1007/978-3-030-75385-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  2. Article ; Online: HIV in pregnancy - An update.

    Chilaka, Victor N / Konje, Justin C

    European journal of obstetrics, gynecology, and reproductive biology

    2020  Volume 256, Page(s) 484–491

    Abstract: Human immunodeficiency virus (HIV) is an infection with a global prevalence and currently no cure or vaccine. Women living with HIV who become pregnant or who acquire the virus during pregnancy are at risk of both maternal and perinatal morbidity and ... ...

    Abstract Human immunodeficiency virus (HIV) is an infection with a global prevalence and currently no cure or vaccine. Women living with HIV who become pregnant or who acquire the virus during pregnancy are at risk of both maternal and perinatal morbidity and mortality mainly if the virus is poorly controlled. Furthermore, there is a risk of vertical transmission to the fetus during pregnancy labour and postpartum through breastfeeding. Appropriate management must be instituted to reduce the consequences of HIV in pregnancy, ideally starting with preconception counselling and planning pregnancies when the viral load is minimum. During pregnancy, an appropriate combined anti-retroviral (cART) medication is mandatory with very close monitoring of the viral load, cluster of differentiation 4 (CD4) cell counts, blood counts, liver and kidney function tests. Planning delivery should not be different in women on cART and suppressed viral loads. However, special care must be taken to limit vertical transmission in those who present late and in whom viral load is unknown or not controlled at the time of delivery. Breastfeeding remains a potential source of infection for the baby and is being discouraged in high-income countries for women living with HIV; however, in low-income countries, the recommendation is exclusive breastfeeding. If breastfeeding must happen, it is best when viral load is suppressed, and cART continued until weaning. Serodiscordant couples present unique problems, and their management should begin with the planning of pregnancy. Emphasis should be on taking steps to prevent HIV transmission to the negative partner and vertical transmission to the new-born.
    MeSH term(s) Anti-HIV Agents/therapeutic use ; Breast Feeding ; Female ; HIV Infections/drug therapy ; HIV Infections/prevention & control ; Humans ; Infant ; Infectious Disease Transmission, Vertical/prevention & control ; Pregnancy ; Pregnancy Complications, Infectious/drug therapy ; Pregnancy Complications, Infectious/prevention & control ; Viral Load
    Chemical Substances Anti-HIV Agents
    Language English
    Publishing date 2020-11-12
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2020.11.034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 837: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Viral Hepatitis in pregnancy.

    Chilaka, Victor N / Konje, Justin C

    European journal of obstetrics, gynecology, and reproductive biology

    2020  Volume 256, Page(s) 287–296

    Abstract: The global prevalence of viral hepatitis is very high and seems to be rising over the years. The infection can profoundly affect pregnant women causing significant maternal and perinatal morbidity and mortality with some strains much worse than others. ... ...

    Abstract The global prevalence of viral hepatitis is very high and seems to be rising over the years. The infection can profoundly affect pregnant women causing significant maternal and perinatal morbidity and mortality with some strains much worse than others. Hepatitis A (HAV) and E (HEV) which are transmitted mainly through the faecal-oral route present as acute hepatitis during pregnancy and are responsible for most local epidemic outbreaks. HAV infection remains self-limiting during pregnancy, while HEV has a higher prevalence and causes significant morbidity. It is also associated with a very high maternal mortality rate (20 %) and requires special attention in endemic areas. HEV vaccines do exist, but the WHO has yet to approve them for general use. Hepatitis B is the most prevalent form and is part of the ante-natal screening program. The presence of HBeAg is associated with high viral loads and infectivity. Antiviral therapy, preferably tenofovir (TDF), is recommended for mothers with viral load ≥ 200,000 IU/mL
    MeSH term(s) Antiviral Agents/therapeutic use ; Child ; DNA, Viral ; Female ; Hepatitis B/diagnosis ; Hepatitis B/drug therapy ; Hepatitis B/epidemiology ; Hepatitis B Surface Antigens/therapeutic use ; Hepatitis B e Antigens/therapeutic use ; Hepatitis B virus/genetics ; Hepatitis C, Chronic/drug therapy ; Hepatitis, Viral, Human/drug therapy ; Humans ; Infant ; Infant, Newborn ; Infectious Disease Transmission, Vertical/prevention & control ; Pregnancy ; Pregnancy Complications, Infectious/diagnosis ; Pregnancy Complications, Infectious/drug therapy ; Pregnancy Complications, Infectious/epidemiology ; Viral Load
    Chemical Substances Antiviral Agents ; DNA, Viral ; Hepatitis B Surface Antigens ; Hepatitis B e Antigens
    Language English
    Publishing date 2020-11-19
    Publishing country Ireland
    Document type Journal Article ; Review
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2020.11.052
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 837: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

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  4. Article ; Online: Post-exposure prophylaxis for Blood-Borne Viral (BBV) Infections.

    Chilaka, Victor N / Hassan, Rudaina / Konje, Justin C

    European journal of obstetrics, gynecology, and reproductive biology

    2020  Volume 255, Page(s) 83–91

    Abstract: Viral infections, such as human immunodeficiency virus (HIV), hepatitis B (HBV) and hepatitis C (HCV), are transmitted either sexually or through blood-borne contamination. The later causes enormous concern within health establishments and health care- ... ...

    Abstract Viral infections, such as human immunodeficiency virus (HIV), hepatitis B (HBV) and hepatitis C (HCV), are transmitted either sexually or through blood-borne contamination. The later causes enormous concern within health establishments and health care-workers. Post-exposure management of HIV rests on the use of triple Anti-Retroviral Therapy (ART), but special care must be taken to choose the right combination for particular circumstances, especially when the subject is pregnant or likely to get pregnant from the event. New-borns of mothers living with HIV require special attention, as maternal viral load plays a central role in their management. When viral load is not detectable, there is a good argument to avoid ART in these infants. Continued maternal ART is encouraged more so in women who intend to breastfeed. The management of exposure to Hepatitis B requires a detailed risk assessment of the source. In high-risk cases, Hep B immunoglobulin will be necessary otherwise passive immunisation with HBV vaccine will suffice. The use of anti-viral treatment for exposure to Hepatitis C remains controversial. New and potent drugs have been introduced but are quite expensive, and the cost-effectiveness of post-exposure therapy should be considered. Curative treatment now exists for HCV, and an option might be to follow exposed subjects up and give them definitive treatment if seroconversion occurs. This review discusses in details the practical steps in the management of sexual and occupational exposure to HIV and other blood-borne viruses with emphasis on preventing infections. Healthcare facilities should have tightly managed protocols for the management of exposure and the ability to start medication as early as possible when indicated.
    MeSH term(s) Female ; HIV Infections/drug therapy ; HIV Infections/prevention & control ; Hepatitis B/prevention & control ; Hepatitis C/drug therapy ; Hepatitis C/prevention & control ; Humans ; Post-Exposure Prophylaxis ; Pregnancy ; Viral Load
    Language English
    Publishing date 2020-10-16
    Publishing country Ireland
    Document type Journal Article ; Review
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2020.10.032
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 837: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: HIV in Pregnancy – an update

    Chilaka, Victor N. / Konje, Justin C.

    Eur J Obstet Gynecol Reprod Biol

    Abstract: Human immunodeficiency virus (HIV) is an infection with a global prevalence and currently no cure or vaccine. Women living with HIV who become pregnant or who acquire the virus during pregnancy are at risk of both maternal and perinatal morbidity and ... ...

    Abstract Human immunodeficiency virus (HIV) is an infection with a global prevalence and currently no cure or vaccine. Women living with HIV who become pregnant or who acquire the virus during pregnancy are at risk of both maternal and perinatal morbidity and mortality mainly if the virus is poorly controlled. Furthermore, there is a risk of vertical transmission to the fetus during pregnancy labour and postpartum through breastfeeding. Appropriate management must be instituted to reduce the consequences of HIV in pregnancy, ideally starting with preconception counselling and planning pregnancies when the viral load is minimum. During pregnancy, an appropriate combined anti-retroviral (cART) medication is mandatory with very close monitoring of the viral load, cluster of differentiation 4 (CD4) cell counts, blood counts, liver and kidney function tests. Planning delivery should not be different in women on cART and suppressed viral loads. However, special care must be taken to limit vertical transmission in those who present late and in whom viral load is unknown or not controlled at the time of delivery. Breastfeeding remains a potential source of infection for the baby and is being discouraged in high-income countries for women living with HIV; however, in low-income countries, the recommendation is exclusive breastfeeding. If breastfeeding must happen, it is best when viral load is suppressed, and cART continued until weaning. Serodiscordant couples present unique problems, and their management should begin with the planning of pregnancy. Emphasis should be on taking steps to prevent HIV transmission to the negative partner and vertical transmission to the new-born.
    Keywords covid19
    Publisher Elsevier; PMC
    Document type Article ; Online
    DOI 10.1016/j.ejogrb.2020.11.034
    Database COVID19

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  6. Article ; Online: Human papillomavirus (HPV) in pregnancy - An update.

    Chilaka, Victor N / Navti, Osric B / Al Beloushi, Mariam / Ahmed, Badredeen / Konje, Justin C

    European journal of obstetrics, gynecology, and reproductive biology

    2021  Volume 264, Page(s) 340–348

    Abstract: Human papilloma viruses (HPV) are small epitheliotropic DNA viruses, of which there are 200 genotypes, 40 of which are known to cause genital infections and are also oncogenic. HPV is the most common sexually transmitted infection. Clinical features vary ...

    Abstract Human papilloma viruses (HPV) are small epitheliotropic DNA viruses, of which there are 200 genotypes, 40 of which are known to cause genital infections and are also oncogenic. HPV is the most common sexually transmitted infection. Clinical features vary from asymptomatic (identified at routine cervical cancer screening) to large lesions on the vulva, vagina, cervix and some extragenital sites. Its prevalence in pregnancy varies from 5.5% to 65% depending on age, geography and gestational age (increasing with gestational age). Infection in pregnancy has been associated with adverse outcomes such as spontaneous miscarriage, preterm birth, placental abnormalities and fetal growth restriction. However, the evidence for these adverse outcomes is varied. Besides being oncogenic (and thus associated with cancer of the cervix in pregnancy), vertical transmission to the fetus/neonate can cause neonatal infections, especially juvenile-onset recurrent oral and respiratory papillomatosis (JORRP). Where there are very large lesions on the vulva, delivery may be obstructed. Diagnosis in pregnancy is mainly by viral PCR or from the clinical appearance of the characteristic lesions on the vulva. Treatment is local by either surgical or laser excision or application of trichloroacetic acid. Podophyllin/podophyllotoxin is contraindicated in pregnancy. HPV Infection is not an indication for caesarean delivery as this has not been shown to prevent vertical transmission. For those diagnosed at routine cervical cancer screening, management should follow guidelines for cervical cancer screening in pregnancy. Vaccination is currently not recommended for pregnant women, although studies on those inadvertently vaccinated in pregnancy have not shown any adverse effects on either the fetus or mother.
    Language English
    Publishing date 2021-07-31
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2021.07.053
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 837: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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