Article ; Online: Biofabricated selenium nanoparticles mediated from Goniothalamus wightii gains biomedical applications and photocatalytic degrading ability
Journal of King Saud University: Science, Vol 34, Iss 8, Pp 102331- (2022)
2022
Abstract: Selenium nanoparticles (SeNPs) have attracted recently in different biomedical applications due to its unique role of metabolic function prevents cellular damage and other severe disease of human. In this study, biosynthesis of SeNPs from Goniothalamus ... ...
| Abstract | Selenium nanoparticles (SeNPs) have attracted recently in different biomedical applications due to its unique role of metabolic function prevents cellular damage and other severe disease of human. In this study, biosynthesis of SeNPs from Goniothalamus wightii (Gw-SeNPs) and characterization were performed on UV–vis spectroscopy showed at 265 nm, it was primarily confirmed the biosynthesis of SeNPs. The XRD pattern revealed that peaks at 29.98 (101), 33.22 (111), 47.42 (200), 65.38 (220) and 77.40 (311)) exhibited a highly crystalline structure. The FE-SEM image proved that the formation of Gw-SeNPs which were polygonal shape. Zeta potential and DLS value of SeNPs recorded as −17.6 mV and 20–110 nm. The results described the synthesized SeNPs have good antibacterial potential on both strains of gram-positive as well as gram-negative pathogens. In vitro antioxidant ability of biogenic Gw-SeNPs has been assessed the inhibition of DPPH free radical scavenging ability with IC50 value was reported as 75.62 (µg/mL) and ABTS inhibitory concentration at 50% was 74.12 (µg/mL). The present findings provide important evidence on cytotoxic effects of Gw-SeNPs on MCF-7 cells. Dye degradation ability of Gw-SeNPs against reactive dyes over the 97% in 150 min in methylene blue dye degradation, the experiment was done under the direct sunlight. Finally, the larvicidal activity against fourth instars mosquito larvae was also executed. In this study, the data indicate that biosynthesis of Gw-SeNPs strongly performed a significant and multifunctional role in biomedical and environmental field. |
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| Keywords | Gw-SeNPs ; Anticancer activity ; Methylene blue ; Antioxidant ; Larvicidal activity ; Science (General) ; Q1-390 |
| Subject code | 500 |
| Language | English |
| Publishing date | 2022-11-01T00:00:00Z |
| Publisher | Elsevier |
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
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