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  1. Article ; Online: Seroprevalencia de anticuerpos anti-Mycoplasma pneumoniae en niños menores de 12 años.

    Sanluis Fenelli, Gabriela / Chiolo, María José / Torres, Fernando Adrián / Balbaryski, Jeanette / Domínguez, Paula / Ossorio, María Fabiana / Rial, María José / Ferrero, Fernando

    Revista chilena de pediatria

    2020  Volume 91, Issue 3, Page(s) 347–352

    Abstract: Introduction: Mycoplasma pneumoniae (Mypn) infection could be occurring at an earlier age due to social pheno mena such as attending daycare centers more frequently and earlier than decades ago.: Objective: to estimate the prevalence of anti-Mypn ... ...

    Title translation Seroprevalence of anti-Mycoplasma pneumoniae antibodies in otherwise healthy children.
    Abstract Introduction: Mycoplasma pneumoniae (Mypn) infection could be occurring at an earlier age due to social pheno mena such as attending daycare centers more frequently and earlier than decades ago.
    Objective: to estimate the prevalence of anti-Mypn antibodies in children aged 0-12 years, and to explore whether age, attendance to daycare center/school, overcrowding or the presence of children aged below 12 years in the households increase the risk of seropositivity.
    Patients and method: Cross-sectional stu dy including healthy children aged 0-12 years which required blood draws for routine laboratory tests. In all cases, the aforementioned variables were recorded and anti-Mypn IgG was determined by enzyme immunoassay. The association between predictors and seropositivity was assessed in a logistic regression model.
    Results: We included 232 patients (average age 56.4 ± 40.0 months). 56.9% attended a daycare center/school, 63.8% co-habited with children under 12 years old, and 15.9% lived in overcrowded households. The prevalence of anti-Mypn antibodies was 14.6%. There were no significant differences between seropositive and seronegative children regarding age (63.1 ± 40.7 vs. 55.4 ± 41.3 months), school/day-care attendance (64.7% vs. 55.5%), overcrowding (14.7% vs. 14.9%), or co-habiting with children (64.7% vs. 63.6%). Age was not an independent predictor of seropositivity in the multivariate model.
    Conclusion: The prevalence of anti-Mypn antibodies in children was 14.6% and age was not a predictor of seropositivity.
    MeSH term(s) Antibodies, Bacterial/blood ; Argentina/epidemiology ; Biomarkers/blood ; Child ; Child Day Care Centers ; Child, Preschool ; Cross-Sectional Studies ; Crowding ; Female ; Humans ; Infant ; Infant, Newborn ; Logistic Models ; Male ; Mycoplasma pneumoniae/immunology ; Pneumonia, Mycoplasma/blood ; Pneumonia, Mycoplasma/diagnosis ; Pneumonia, Mycoplasma/epidemiology ; Prevalence ; Risk Factors ; Schools ; Seroepidemiologic Studies
    Chemical Substances Antibodies, Bacterial ; Biomarkers
    Language Spanish
    Publishing date 2020-07-29
    Publishing country Chile
    Document type Journal Article
    ZDB-ID 954077-5
    ISSN 0717-6228 ; 0034-7396 ; 0370-4106
    ISSN (online) 0717-6228
    ISSN 0034-7396 ; 0370-4106
    DOI 10.32641/rchped.v91i3.1476
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Children hospitalized for COVID-19 during the first winter of the pandemic in Buenos Aires, Argentina

    Raiden, Silvina / Cairoli, Hector / Potasnik, Javier / Di Lalla, Sandra / Chiolo, Maria Jose / Torres, Fernando Adrian / Dominguez, Paula / Ferrero, Fernando

    medRxiv

    Abstract: Background: Although there are reports on COVID-19 in pediatrics, it is possible that the characteristics of each population, their health systems and how they faced the pandemic made the disease show distinctive features in different countries. We aimed ...

    Abstract Background: Although there are reports on COVID-19 in pediatrics, it is possible that the characteristics of each population, their health systems and how they faced the pandemic made the disease show distinctive features in different countries. We aimed to describe the characteristics of patients hospitalized for COVID-19 in a tertiary pediatric hospital in the City of Buenos Aires, Argentina. Methods: Descriptive study, including all patients hospitalized for COVID-19 in a tertiary pediatric hospital, from 04/26/2020 to 10/31/2020. Demographic, clinical and epidemiological characteristics of the patients are described. Results: In the studied period 578 children and adolescents were hospitalized for COVID-19. The median age was 4.2 years and 83% had a history of close contact with a confirmed COVID-19 case. Regarding severity, 30.8% were asymptomatic, 60.4% mild, 7.4% moderate, and 1.4% severe. Among those with symptoms, the most frequent was fever, followed by sore throat and cough. Conclusion: We reported 578 cases of children and adolescents hospitalized for COVID-19, most of them showed a mild or asymptomatic condition.
    Keywords covid19
    Language English
    Publishing date 2020-11-06
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2020.11.05.20225300
    Database COVID19

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  3. Article ; Online: Assessment of the scientific output of Hospital de Niños Pedro de Elizalde, 2000-2011.

    Domínguez, Paula / Chiolo, María José / Davenport, María Carolina / Di Lalla, Sandra / Martins, Andrea / Ferrero, Fernando

    Archivos argentinos de pediatria

    2014  Volume 112, Issue 2, Page(s) 147–152

    Abstract: Introduction: Monitoring article submissions and publications developed by an institution is a suitable measure to assess its scientific output.: Objectives: To estimate the proportion of research projects that were completed and had results ... ...

    Abstract Introduction: Monitoring article submissions and publications developed by an institution is a suitable measure to assess its scientific output.
    Objectives: To estimate the proportion of research projects that were completed and had results submitted/published by a pediatric hospital; to describe research project design and characteristics; to outline limitations on research development or dissemination.
    Methods: Descriptive and analytical study including scientific studies approved to be developed between 2000 and 2011. Each investigator was contacted and asked to participate in a survey on research development, result dissemination and possible reasons for not completing or disseminating a study.
    Results: The survey was completed by the authors of 197 projects (60.9% completed, 16.2% ongoing, 12.7% cancelled, and 10.2% put off). Drug trials were most likely not to be completed. Of all completed projects (n = 120), 45.8% were clinical research studies, 43.3% were epidemiological studies, and 10% were related to health services. When analyzed by design, 77.5% were observational studies while 22.5% were experimental ones. In terms of scope, 69.1% were restricted to the hospital, 16.6% were international multicenter studies, and 14.1% were national multicenter studies. Only 36.6% of projects received funding. Lack of time (20%) and insufficient sample size (10%) were the most commonly indicated reasons for non dissemination. A total of 78.3% of projects were presented in conferences and 37.5% were published. The presence of funding was the only independent predictor of publication.
    Conclusions: Of all approved projects, 60.9% were completed; of them, 78.3% were presented in conferences and 37.5% were published. Drug trials were most likely not to be completed, and funded studies had more chances of being published.
    MeSH term(s) Biomedical Research ; Child ; Hospitals, Pediatric ; Humans ; Publishing/statistics & numerical data ; Time Factors
    Language Spanish
    Publishing date 2014-02-06
    Publishing country Argentina
    Document type Journal Article
    ZDB-ID 424449-7
    ISSN 1668-3501 ; 0325-0075 ; 0004-0487
    ISSN (online) 1668-3501
    ISSN 0325-0075 ; 0004-0487
    DOI 10.5546/aap.2014.eng.147
    Database MEDical Literature Analysis and Retrieval System OnLINE

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