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Article: Primary cilia in osteoblasts and osteocytes are required for skeletal development and mechanotransduction.

Moraes de Lima Perini, Mariana / Pugh, Julie N / Scott, Elizabeth M / Bhula, Karan / Chirgwin, Austin / Reul, Olivia N / Berbari, Nicolas F / Li, Jiliang

bioRxiv : the preprint server for biology

2023  

Abstract: Primary cilia have been involved in the development and mechanosensation of various tissue types, including bone. In this study, we explored the mechanosensory role of primary cilia in bone growth and adaptation by examining two cilia specific genes, ... ...

Abstract Primary cilia have been involved in the development and mechanosensation of various tissue types, including bone. In this study, we explored the mechanosensory role of primary cilia in bone growth and adaptation by examining two cilia specific genes, IFT88 and MKS5, required for proper cilia assembly and function. To analyze the role of primary cilia in osteoblasts, Osx1-GFP:Cre mice were bred with IFT88
Language English
Publishing date 2023-12-18
Publishing country United States
Document type Preprint
DOI 10.1101/2023.12.15.570609
Database MEDical Literature Analysis and Retrieval System OnLINE

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