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  1. Article: An Endoscopic Illusion!

    Sandoval, Victoria / Chittajallu, Vibhu / Haddad, Fady G

    ACG case reports journal

    2024  Volume 11, Issue 3, Page(s) e01278

    Language English
    Publishing date 2024-03-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000001278
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Methotrexate-Induced Apoptotic Colopathy in Crohn's Disease.

    Chittajallu, Vibhu / Liu, Wendy / Nguyen, Vu

    ACG case reports journal

    2023  Volume 10, Issue 2, Page(s) e00980

    Abstract: Apoptotic colopathy is a pattern of injury not frequently associated with Crohn's disease (CD) despite its association with medications used in CD management. We describe a patient with CD on methotrexate who underwent a diagnostic colonoscopy for ... ...

    Abstract Apoptotic colopathy is a pattern of injury not frequently associated with Crohn's disease (CD) despite its association with medications used in CD management. We describe a patient with CD on methotrexate who underwent a diagnostic colonoscopy for abdominal pain and diarrhea, with biopsies demonstrating apoptotic colopathy. After methotrexate discontinuation, repeat colonoscopy demonstrated resolution of apoptotic colopathy in addition to diarrhea improvement.
    Language English
    Publishing date 2023-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000000980
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Utilization of Anti-obesity Medications After Bariatric Surgery: Analysis of a Large National Database.

    Firkins, Stephen A / Chittajallu, Vibhu / Flora, Bailey / Yoo, Heesoo / Simons-Linares, Roberto

    Obesity surgery

    2024  Volume 34, Issue 5, Page(s) 1415–1424

    Abstract: Purpose: A significant proportion of patients experience insufficient weight loss or weight regain after bariatric surgery. There is a paucity of literature describing anti-obesity medication (AOM) use following bariatric surgery. We sought to identify ... ...

    Abstract Purpose: A significant proportion of patients experience insufficient weight loss or weight regain after bariatric surgery. There is a paucity of literature describing anti-obesity medication (AOM) use following bariatric surgery. We sought to identify prevalence and trends of AOM use following bariatric surgery.
    Materials and methods: We utilized the IBM Explorys® database to identify all adults with prior bariatric surgery (Roux-en-Y gastric bypass or sleeve gastrectomy). Those prescribed AOMs (semaglutide, liraglutide, topiramate, phentermine/topiramate, naltrexone/bupropion, orlistat) within 5 years of surgery were further identified. Data was analyzed to characterize AOM utilization among different age, demographic, and comorbid populations.
    Results: A total of 59,160 adults with prior bariatric surgery were included. Among AOMs studies, prevalence of use was highest for topiramate (8%), followed by liraglutide (2.9%), phentermine/topiramate (1.03%), naltrexone/bupropion (0.95%) semaglutide (0.52%), and orlistat (0.17%). Age distribution varied, with the highest utilization among those age 35-39 years for topiramate, 40-44 years for phentermine/topiramate and naltrexone/bupropion, 45-49 years for semaglutide, and 65-69 years for liraglutide and orlistat. African American race was associated with higher utilization across all AOMs. Among comorbidities, hypertension, hyperlipidemia, and diabetes mellitus were most associated with AOM use.
    Conclusion: Despite a relatively high incidence of weight regain, AOMs are underutilized following bariatric surgery. It is imperative that barriers to their use be addressed and that AOMs be considered earlier and more frequently in patients with insufficient weight loss or weight regain after bariatric surgery.
    MeSH term(s) Adult ; Humans ; Orlistat ; Topiramate/therapeutic use ; Liraglutide/therapeutic use ; Naltrexone/therapeutic use ; Bupropion ; Obesity, Morbid/surgery ; Retrospective Studies ; Anti-Obesity Agents/therapeutic use ; Bariatric Surgery ; Gastric Bypass ; Phentermine/therapeutic use ; Weight Loss ; Weight Gain ; Arthritis ; Connective Tissue Diseases ; Hearing Loss, Sensorineural ; Retinal Detachment
    Chemical Substances Orlistat (95M8R751W8) ; Topiramate (0H73WJJ391) ; Liraglutide (839I73S42A) ; Naltrexone (5S6W795CQM) ; Bupropion (01ZG3TPX31) ; Anti-Obesity Agents ; Phentermine (C045TQL4WP)
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-024-07181-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Endoscopic balloon dilation management for benign duodenal stenosis.

    Chittajallu, Vibhu / Omar, Yazan Abu / Simons-Linares, C Roberto / Chahal, Prabhleen

    Surgical endoscopy

    2023  Volume 37, Issue 5, Page(s) 3610–3618

    Abstract: Background and aims: Benign duodenal stenosis (BDS) is most commonly caused by peptic ulcer disease (PUD). Endoscopic balloon dilation (EBD) is the recommended initial management despite limited supporting literature. Our study investigated the ... ...

    Abstract Background and aims: Benign duodenal stenosis (BDS) is most commonly caused by peptic ulcer disease (PUD). Endoscopic balloon dilation (EBD) is the recommended initial management despite limited supporting literature. Our study investigated the etiologic spectrum of BDS and its response to endoscopic dilation.
    Methods: We performed a cohort study of a prospectively maintained database of BDS at our large tertiary academic center between 2002 and 2018. All patients who underwent EBD were analyzed. Dilation was performed using through-the-scope balloons. Technical and clinical successes of initial and repeat EBD were compared. Descriptive statistics, univariate, and multivariate analysis were performed.
    Results: The study included 86 patients with 54.7% female gender. Etiologies included 39 patients with PUD (45.3%), 19 patients with Crohn's disease (22.1%), 23 patients had idiopathic etiologies (26.7%), and 5 patients were listed as other etiologies (5.8%). Proximal stricture location (1st part of duodenum) occurred in 66% of females, whereas distal duodenal involvement was seen in 63.6% of males (p value 0.007). Usage of PPI was associated with 3.6 times higher clinical success rate (p value 0.04). Technical (97.4%) and clinical (77.8%) successes for index dilations in PUD were not significantly better than those of non-PUD patients (p values 0.99, 0.52).
    Conclusion: EBD has both a high technical and clinical success for BDS regardless of etiology and should be considered over initial surgical intervention due to low risk profile. Males tend to have more distal duodenal involvement, and PPI usage is an independent predictor for clinical success.
    MeSH term(s) Male ; Humans ; Female ; Dilatation ; Cohort Studies ; Treatment Outcome ; Endoscopy ; Peptic Ulcer/complications ; Retrospective Studies
    Language English
    Publishing date 2023-01-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-022-09844-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Underutilization of pancreatic enzyme replacement therapy in pancreatic cancer and chronic pancreatitis.

    Kumar, Prabhat / Chander, Apoorva / Chittajallu, Vibhu / Grewal, Udhayvir Singh

    Journal of internal medicine

    2023  Volume 294, Issue 5, Page(s) 679–681

    Language English
    Publishing date 2023-06-01
    Publishing country England
    Document type Letter
    ZDB-ID 96274-0
    ISSN 1365-2796 ; 0954-6820
    ISSN (online) 1365-2796
    ISSN 0954-6820
    DOI 10.1111/joim.13671
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Odynophagia Secondary to Mpox-Associated Esophageal Ulceration.

    Chittajallu, Vibhu / Vozzo, Catherine / Friedman, Kenneth / Glessing, Brooke / Nguyen, Vu

    The American journal of gastroenterology

    2022  Volume 118, Issue 5, Page(s) 774

    MeSH term(s) Humans ; Mpox (monkeypox)/complications ; Esophageal Diseases/chemically induced ; Esophageal Diseases/diagnosis ; Esophageal Diseases/complications ; Deglutition Disorders/complications ; Peptic Ulcer/complications
    Language English
    Publishing date 2022-12-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390122-1
    ISSN 1572-0241 ; 0002-9270
    ISSN (online) 1572-0241
    ISSN 0002-9270
    DOI 10.14309/ajg.0000000000002095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Lumbar Artery Pseudoaneurysms Presenting as a Novel Complication of Severe, Necrotizing Pancreatitis.

    Khurana, Akash T / Chittajallu, Vibhu / Reed, Steven / Sutter, Christopher / Glessing, Brooke

    ACG case reports journal

    2023  Volume 10, Issue 8, Page(s) e01129

    Abstract: Splanchnic artery pseudoaneurysms are a known complication of necrotizing pancreatitis. Lumbar artery pseudoaneurysms are rare and usually associated with trauma, renal biopsy, or spinal procedures. We present a rare case of lumbar artery pseudoaneurysms ...

    Abstract Splanchnic artery pseudoaneurysms are a known complication of necrotizing pancreatitis. Lumbar artery pseudoaneurysms are rare and usually associated with trauma, renal biopsy, or spinal procedures. We present a rare case of lumbar artery pseudoaneurysms as a complication of necrotizing pancreatitis. A 55-year-old man initially presented with necrotizing biliary pancreatitis complicated by peripancreatic necrotic fluid collections and walled-off necrosis requiring multiple endoscopic ultrasound-guided necrosectomies. Inferoposterior extension of collections to the retroperitoneum caused lumbar artery pseudoaneurysms, leading to hemorrhagic shock from retroperitoneal and intraperitoneal hemorrhages.
    Language English
    Publishing date 2023-08-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000001129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Stent gone rogue: endoscopic removal of a 3-year-old embedded cystogastrostomy stent.

    Simons-Linares, C Roberto / Chittajallu, Vibhu / Chahal, Prabhleen

    VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy

    2020  Volume 5, Issue 11, Page(s) 548–551

    Language English
    Publishing date 2020-09-26
    Publishing country United States
    Document type Journal Article
    ISSN 2468-4481
    ISSN (online) 2468-4481
    DOI 10.1016/j.vgie.2020.06.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Do Not Skip the Retroflexion: A Case of Disseminated Anorectal Mucosal Melanoma.

    Chittajallu, Vibhu / Simons-Linares, Carlos Roberto / Oshilaja, Olaronke / Chahal, Prabhleen

    ACG case reports journal

    2021  Volume 8, Issue 2, Page(s) e00513

    Abstract: Less than 4% of melanomas are of mucosal origin, with primary anorectal mucosal melanomas comprising a small subset. Mucosal melanomas are often diagnosed at an advanced stage due to delay in patient presentation and obscured tumor origins leading to a ... ...

    Abstract Less than 4% of melanomas are of mucosal origin, with primary anorectal mucosal melanomas comprising a small subset. Mucosal melanomas are often diagnosed at an advanced stage due to delay in patient presentation and obscured tumor origins leading to a more aggressive behavior and less favorable prognosis when compared with cutaneous melanomas. We present a case of metastatic anorectal mucosal melanoma with a negative colonoscopy 1 year earlier.
    Language English
    Publishing date 2021-02-03
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000000513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Association of Bariatric Surgery with Risk of Incident Obesity-Associated Malignancies: a Multi-center Population-Based Study.

    Chittajallu, Vibhu / Mansoor, Emad / Perez, Jaime / Omar, Yazan Abu / Firkins, Stephen A / Yoo, Heesoo / Baggott, Brian / Simons-Linares, Roberto

    Obesity surgery

    2023  Volume 33, Issue 12, Page(s) 4065–4069

    Abstract: Introduction: Obesity has a known association with certain types of malignancy, and we aimed to determine whether bariatric surgery has a protective effect against de novo obesity-associated cancer development in adult patients.: Methods: We ... ...

    Abstract Introduction: Obesity has a known association with certain types of malignancy, and we aimed to determine whether bariatric surgery has a protective effect against de novo obesity-associated cancer development in adult patients.
    Methods: We performed a multi-center retrospective cohort studying utilizing TriNetX national database. Patients were identified utilizing ICD-10-CM coding, and propensity score matching was performed. We compared patients with obesity who underwent bariatric surgery to patients with obesity who did not undergo bariatric surgery.
    Results: We initially identified 60,285 patients in the bariatric surgery group and 1,570,440 patients in nonsurgical control group. After propensity score matching, we included 55,789 patients in each patient cohort. The cumulative incidence of de novo obesity-associated cancers at 10 years was 4.0% (2206 patients) in the bariatric surgery group and 8.9% (4,960 patients) in the nonsurgical control group (HR 0.482 [95% CI 0.459-0.507]). The bariatric surgery group had lower incidence proportions for de novo breast cancer (HR 0.753 [CI 0.678-0.836]), colon cancer (HR 0.638 [CI 0.541-0.752]), liver cancer (HR 0.370 [CI 0.345-0.396]), ovarian cancer (HR 0.654 [CI 0.531-0.806]), and endometrial cancer (HR 0.448 [CI 0.362-0.556]) when compared to the nonsurgical control group.
    Conclusion: We noted that bariatric surgery is associated with a significantly lower cumulative incidence of de novo obesity-associated cancer compared to a nonsurgical matched control group. Incidence proportions of de novo breast, colon, liver, ovarian, and endometrial cancer were significantly lower in adult patients with obesity in the bariatric surgery group compared to the nonsurgical group.
    MeSH term(s) Adult ; Female ; Humans ; Retrospective Studies ; Obesity, Morbid/surgery ; Obesity/complications ; Obesity/epidemiology ; Obesity/surgery ; Bariatric Surgery ; Endometrial Neoplasms/complications
    Language English
    Publishing date 2023-11-16
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-023-06926-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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