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  1. Article ; Online: Antigranulocyte macrophage colony stimulating factor autoantibodies: The underlying cause in seemingly immunocompetent patients with disseminated cryptococcosis.

    Fang, Wei-Cheng / Chiu, Li-Wen

    The Journal of dermatology

    2024  

    Language English
    Publishing date 2024-03-03
    Publishing country England
    Document type Letter
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.17174
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Evaluation of Optic Nerve Head Microcirculation in Open-Angle Glaucoma Patients with Unilateral Visual Field Defect.

    Lin, Pei-Wen / Chiu, Li-Wen

    Ophthalmic research

    2024  Volume 67, Issue 1, Page(s) 257–265

    Abstract: Introduction: Microcirculation of optic nerve head (ONH) in open-angle glaucoma (OAG) patients with unilateral visual field (VF) loss has yet to be fully investigated, especially the perimetrically unaffected fellow eyes.: Methods: Thirty-eight OAG ... ...

    Abstract Introduction: Microcirculation of optic nerve head (ONH) in open-angle glaucoma (OAG) patients with unilateral visual field (VF) loss has yet to be fully investigated, especially the perimetrically unaffected fellow eyes.
    Methods: Thirty-eight OAG patients with VF defect in one eye and normal VF in the other eye, and thirty-one healthy participants were analyzed. All participants underwent laser speckle flowgraphy (LSFG), spectral-domain optical coherence tomography (SD-OCT) imaging, and VF test for further analyses. LSFG measurements included mean blur rate in all area of ONH (MA), big vessel area of ONH (MV), and tissue area of ONH (MT). SD-OCT parameters included circumpapillary retinal nerve fiber layer (cpRNFL) thickness and macula thicknesses. The difference of LSFG and SD-OCT indices between glaucoma patients and healthy controls were compared. The diagnostic accuracy was analyzed with the areas under the receiver operating characteristic curves (AROCs).
    Results: Global cpRNFL thickness and macular thickness in unaffected eyes of OAG patients were higher than their fellow eyes and lower than healthy eyes. MA and MV in healthy eyes and unaffected eyes were significantly higher than in affected eyes. MT in unaffected eyes of OAG patients was higher than in their fellow affected eyes but lower than in healthy eyes. The AROCs were highest for cpRNFL (0.925), followed by macular thickness (0.838), and MT (0.834).
    Conclusions: ONH microcirculation in perimetrically unaffected fellow eyes was decreased in OAG patients with unilateral VF loss. LSFG can detect changes of ONH in high-risk eyes before detectable VF damage, which may reflect the vascular pathophysiology for glaucoma.
    MeSH term(s) Humans ; Glaucoma, Open-Angle/physiopathology ; Glaucoma, Open-Angle/diagnosis ; Male ; Female ; Optic Disk/blood supply ; Microcirculation/physiology ; Visual Fields/physiology ; Tomography, Optical Coherence/methods ; Middle Aged ; Nerve Fibers/pathology ; Retinal Ganglion Cells/pathology ; Aged ; Intraocular Pressure/physiology ; Visual Field Tests ; Laser-Doppler Flowmetry ; ROC Curve ; Retinal Vessels/physiopathology ; Retinal Vessels/diagnostic imaging
    Language English
    Publishing date 2024-03-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 205708-6
    ISSN 1423-0259 ; 0030-3747
    ISSN (online) 1423-0259
    ISSN 0030-3747
    DOI 10.1159/000538407
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Neonatal Cephalic Pustulosis.

    Fang, Wei-Cheng / Chiu, Li-Wen

    The New England journal of medicine

    2023  Volume 389, Issue 6, Page(s) e10

    MeSH term(s) Humans ; Infant, Newborn ; Dermatomycoses/drug therapy ; Dermatomycoses/etiology ; Dermatomycoses/microbiology ; Head/microbiology ; Suppuration
    Language English
    Publishing date 2023-08-05
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMicm2301685
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Comparison of the correlation between serum autoantibodies against aldehyde dehydrogenase 2 and thyrotropin receptor in patients with Graves' ophthalmopathy.

    Lin, Chia-Ching / Chiu, Li-Wen / Lee, Po-Yen / Chen, Kuo-Jen / Cheng, Kai-Chun

    Indian journal of ophthalmology

    2024  Volume 72, Issue 2, Page(s) 298–299

    MeSH term(s) Humans ; Aldehyde Dehydrogenase ; Autoantibodies ; Graves Ophthalmopathy/diagnosis ; Receptors, Thyrotropin
    Chemical Substances Aldehyde Dehydrogenase (EC 1.2.1.3) ; Autoantibodies ; Receptors, Thyrotropin
    Language English
    Publishing date 2024-01-25
    Publishing country India
    Document type Comparative Study ; Journal Article
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/IJO.IJO_673_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Analysis of macular choroidal thickness in normal Taiwanese eyes by enhanced depth imaging optical coherence tomography.

    Chiu, Li-Wen / Chang, Yo-Chen / Chen, Kuo-Jen / Cheng, Kai-Chun

    The Kaohsiung journal of medical sciences

    2023  Volume 39, Issue 12, Page(s) 1245–1246

    MeSH term(s) Tomography, Optical Coherence/methods ; Choroid/diagnostic imaging
    Language English
    Publishing date 2023-09-01
    Publishing country China (Republic : 1949- )
    Document type Letter
    ZDB-ID 639302-0
    ISSN 2410-8650 ; 0257-5655
    ISSN (online) 2410-8650
    ISSN 0257-5655
    DOI 10.1002/kjm2.12750
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Dermoscopic findings in a patient with cutaneous plasmacytoma.

    Chiu, Li-Wen / Su, Yue-Chiu / Hu, Stephen Chu-Sung

    The Australasian journal of dermatology

    2022  Volume 63, Issue 2, Page(s) e177–e179

    MeSH term(s) Administration, Cutaneous ; Humans ; Plasmacytoma/diagnostic imaging ; Skin ; Skin Neoplasms
    Language English
    Publishing date 2022-02-01
    Publishing country Australia
    Document type Letter
    ZDB-ID 138052-7
    ISSN 1440-0960 ; 0004-8380
    ISSN (online) 1440-0960
    ISSN 0004-8380
    DOI 10.1111/ajd.13792
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Contact-Free Atrial Fibrillation Screening with Attention Network.

    Wu, Yi-Chiao / Lin, Chun-Hsien / Chiu, Li-Wen / Wu, Bing-Fei / Chung, Meng-Liang / Tang, Sung-Chun / Sun, Yu

    IEEE journal of biomedical and health informatics

    2024  Volume PP

    Abstract: Atrial Fibrillation (AF) screening from face videos has become popular with the trend of telemedicine and telehealth in recent years. In this study, the largest facial image database for camera-based AF detection is proposed. There are 657 participants ... ...

    Abstract Atrial Fibrillation (AF) screening from face videos has become popular with the trend of telemedicine and telehealth in recent years. In this study, the largest facial image database for camera-based AF detection is proposed. There are 657 participants from two clinical sites and each of them is recorded for about 10 minutes of video data, which can be further processed as over 10,000 segments around 30 seconds, where the duration setting is referred to the guideline of AF diagnosis. It is also worth noting that, 2,979 segments are segment-wise labeled, that is, every rhythm is independently labeled with AF or not. Besides, all labels are confirmed by the cardiologist manually. Various environments, talking, facial expressions, and head movements are involved in data collection, which meets the situations in practical usage. Specific to camera-based AF screening, a novel CNN-based architecture equipped with an attention mechanism is proposed. It is capable of fusing heartbeat consistency, heart rate variability derived from remote photoplethysmography, and motion features simultaneously to reliable outputs. With the proposed model, the performance of intra-database evaluation comes up to 96.62% of sensitivity, 90.61% of specificity, and 0.96 of AUC. Furthermore, to check the capability of adaptation of the proposed method thoroughly, the cross-database evaluation is also conducted, and the performance also reaches about 90% on average with the AUCs being over 0.94 in both clinical sites.
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2695320-1
    ISSN 2168-2208 ; 2168-2194
    ISSN (online) 2168-2208
    ISSN 2168-2194
    DOI 10.1109/JBHI.2024.3368049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Self-assembled surgical headlights in dermatologic procedures.

    Fang, Wei-Cheng / Chiu, Li-Wen / Sun, Yng / Yang, Ting-Ting

    Journal of the American Academy of Dermatology

    2022  Volume 89, Issue 4, Page(s) e149–e150

    MeSH term(s) Humans ; Visual Perception ; Lighting ; Dermatologic Surgical Procedures
    Language English
    Publishing date 2022-09-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2022.09.042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Contactless Blood Pressure Measurement Via Remote Photoplethysmography With Synthetic Data Generation Using Generative Adversarial Networks.

    Wu, Bing-Fei / Chiu, Li-Wen / Wu, Yi-Chiao / Lai, Chun-Chih / Cheng, Hao-Min / Chu, Pao-Hsien

    IEEE journal of biomedical and health informatics

    2024  Volume 28, Issue 2, Page(s) 621–632

    Abstract: Remote photoplethysmography (rPPG) has been used to measure vital signs such as heart rate, heart rate variability, blood pressure (BP), and blood oxygen. Recent studies adopt features developed with photoplethysmography (PPG) to achieve contactless BP ... ...

    Abstract Remote photoplethysmography (rPPG) has been used to measure vital signs such as heart rate, heart rate variability, blood pressure (BP), and blood oxygen. Recent studies adopt features developed with photoplethysmography (PPG) to achieve contactless BP measurement via rPPG. These features can be classified into two groups: time or phase differences from multiple signals, or waveform feature analysis from a single signal. Here we devise a solution to extract the time difference information from the rPPG signal captured at 30 FPS. We also propose a deep learning model architecture to estimate BP from the extracted features. To prevent overfitting and compensate for the lack of data, we leverage a multi-model design and generate synthetic data. We also use subject information related to BP to assist in model learning. For real-world usage, the subject information is replaced with values estimated from face images, with performance that is still better than the state-of-the-art. To our best knowledge, the improvements can be achieved because of: 1) the model selection with estimated subject information, 2) replacing the estimated subject information with the real one, 3) the InfoGAN assistance training (synthetic data generation), and 4) the time difference features as model input. To evaluate the performance of the proposed method, we conduct a series of experiments, including dynamic BP measurement for many single subjects and nighttime BP measurement with infrared lighting. Our approach reduces the MAE from 15.49 to 8.78 mmHg for systolic blood pressure (SBP) and 10.56 to 6.16 mmHg for diastolic blood pressure(DBP) on a self-constructed rPPG dataset. On the Taipei Veterans General Hospital(TVGH) dataset for nighttime applications, the MAE is reduced from 21.58 to 11.12 mmHg for SBP and 9.74 to 7.59 mmHg for DBP, with improvement ratios of 48.47% and 22.07% respectively.
    MeSH term(s) Humans ; Blood Pressure ; Photoplethysmography/methods ; Blood Pressure Determination/methods ; Heart Rate ; Infrared Rays
    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2695320-1
    ISSN 2168-2208 ; 2168-2194
    ISSN (online) 2168-2208
    ISSN 2168-2194
    DOI 10.1109/JBHI.2023.3265857
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: M2 Polarization May Contribute to Formation of Granulomatous Dermatitis in Progression of Myelodysplastic Syndrome to Acute Myeloid Leukemia.

    Fang, Wei-Cheng / Du, Jeng-Shiun / Su, Yue-Chiu / Chiu, Li-Wen / Yang, Ting-Ting

    Dermatology practical & conceptual

    2023  Volume 13, Issue 4

    Language English
    Publishing date 2023-10-01
    Publishing country Austria
    Document type Letter
    ZDB-ID 2685397-8
    ISSN 2160-9381
    ISSN 2160-9381
    DOI 10.5826/dpc.1304a241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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