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  1. Book ; Online: Dietary Intakes and Metabolic Disorders

    Chiva-Blanch, Gemma / Cofán, Montserrat

    2022  

    Keywords Research & information: general ; Biology, life sciences ; Food & society ; animal experimentation ; diet ; nutrition ; ingredients ; lard ; fibers ; fructose ; diet coloring ; autoclaving ; irradiation ; Passiflora setacea ; bioactive compounds ; phenolic compounds ; cardiovascular diseases ; nutrigenomics ; gene expression ; immune system ; cytokines ; insulin ; HDL ; diabetes mellitus ; dietary pattern ; metabotype ; metabolic phenotype ; Mediterranean Diet Score ; Alternate Healthy Eating Index ; atherosclerosis ; plaque burden ; lycopene ; tomato ; type 2 diabetes mellitus ; cis- and trans-isomers ; nutrients ; hypertension ; blood pressure ; management ; prevention ; mitochondria ; metabolic syndrome ; mitochondrial dysfunction ; balanced diet ; lifestyle ; Mediterranean diet ; plant-based diet ; DASH diet ; low-carbohydrate diet ; high-protein diet ; low-fat diet ; omega-3 fatty acids ; metabolism ; inflammation ; atherothrombosis ; clinical trials ; legacy effect ; metabolic memory ; cardiovascular disease ; diabetes ; dyslipidaemia ; abdominal obesity ; animal protein ; protein intake ; Alpha-linolenic acid ; docosahexaenoic acid ; rumenic acid ; punicic acid ; enriched eggs ; waist circumference ; obesity
    Language English
    Size 1 electronic resource (234 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030374345
    ISBN 9783036548340 ; 3036548343
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Methods of Isolation and Purification of Extracellular Vesicles from Different Biological Matrixes: Special Issue at a Glance.

    Chiva-Blanch, Gemma

    Journal of visualized experiments : JoVE

    2023  , Issue 192

    Abstract: Articles discussed: Hanine El Itawi, H., et al. Isolation of Splenic Microvesicles in a Murine Model of Intraperitoneal Bacterial Infection. J Vis Exp. 186, DOI: 10.3791/63480 (2022) Jones, M.T., Manioci S.W., S1, Russell, A.E. Size Exclusion ... ...

    Abstract Articles discussed: Hanine El Itawi, H., et al. Isolation of Splenic Microvesicles in a Murine Model of Intraperitoneal Bacterial Infection. J Vis Exp. 186, DOI: 10.3791/63480 (2022) Jones, M.T., Manioci S.W., S1, Russell, A.E. Size Exclusion Chromatography for Separating Extracellular Vesicles from Conditioned Cell Culture Media. J Vis Exp. 186, DOI: 10.3791/63614 (2022) Ryan, J.M., Dobos, K.M., Kruh-Garcia, N.A. Mycobacterium tuberculosis Extracellular Vesicle Enrichment through Size Exclusion Chromatography. J Vis Exp. 186, DOI: 10.3791/63895 (2022) Valle-Tamayo, N., et al. Enrichment of Astrocyte-Derived Extracellular Vesicles from Human Plasma J Vis Exp. 186, DOI: 10.3791/64107 (2022) Koh, B., et al. A Simple Benchtop Filtration Method to Isolate Small Extracellular Vesicles from Human Mesenchymal Stem Cells J Vis Exp. 186, DOI: 10.3791/64106 (2022).
    MeSH term(s) Humans ; Animals ; Mice ; Extracellular Vesicles ; Cell-Derived Microparticles ; Astrocytes ; Chromatography, Gel ; Culture Media, Conditioned
    Chemical Substances Culture Media, Conditioned
    Language English
    Publishing date 2023-02-10
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2259946-0
    ISSN 1940-087X ; 1940-087X
    ISSN (online) 1940-087X
    ISSN 1940-087X
    DOI 10.3791/64963
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Lessons from the spatiotemporal expression patterns of RNA vs. proteins during the cell cycle.

    Chiva-Blanch, Gemma / Mayr, Manuel

    Cardiovascular research

    2021  Volume 117, Issue 8, Page(s) e91–e93

    MeSH term(s) Cell Cycle ; Genomics ; Proteomics ; RNA/genetics
    Chemical Substances RNA (63231-63-0)
    Language English
    Publishing date 2021-06-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 80340-6
    ISSN 1755-3245 ; 0008-6363
    ISSN (online) 1755-3245
    ISSN 0008-6363
    DOI 10.1093/cvr/cvab196
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Extracellular vesicles signal from bones to vessels: an answer to the 'calcification paradox'?

    Chiva-Blanch, Gemma / Davidson, Sean M

    Cardiovascular research

    2022  Volume 118, Issue 11, Page(s) e75–e77

    MeSH term(s) Calcinosis ; Extracellular Vesicles ; Humans ; MicroRNAs
    Chemical Substances MicroRNAs
    Language English
    Publishing date 2022-08-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80340-6
    ISSN 1755-3245 ; 0008-6363
    ISSN (online) 1755-3245
    ISSN 0008-6363
    DOI 10.1093/cvr/cvac111
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Scientists on the Spot: A matter of blood flow.

    Chiva-Blanch, Gemma / Evans, Paul C

    Cardiovascular research

    2021  Volume 117, Issue 12, Page(s) e162–e163

    MeSH term(s) Animals ; Arteries/pathology ; Arteries/physiopathology ; Atherosclerosis/history ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Atherosclerosis/physiopathology ; Biomedical Research/history ; Hemodynamics ; History, 20th Century ; History, 21st Century ; Humans ; Mechanotransduction, Cellular ; Plaque, Atherosclerotic ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Regional Blood Flow ; Stress, Mechanical
    Chemical Substances RNA, Small Interfering
    Language English
    Publishing date 2021-10-30
    Publishing country England
    Document type Biography ; Historical Article ; Interview ; Video-Audio Media
    ZDB-ID 80340-6
    ISSN 1755-3245 ; 0008-6363
    ISSN (online) 1755-3245
    ISSN 0008-6363
    DOI 10.1093/cvr/cvab320
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Targeted diets for the gut microbiota and the potential cardiovascular effects.

    Chiva-Blanch, Gemma / Müller, Dominik N

    Cardiovascular research

    2021  Volume 117, Issue 11, Page(s) e135–e137

    MeSH term(s) Diet ; Gastrointestinal Microbiome
    Language English
    Publishing date 2021-12-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 80340-6
    ISSN 1755-3245 ; 0008-6363
    ISSN (online) 1755-3245
    ISSN 0008-6363
    DOI 10.1093/cvr/cvab276
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Benefits and Risks of Moderate Alcohol Consumption on Cardiovascular Disease: Current Findings and Controversies.

    Chiva-Blanch, Gemma / Badimon, Lina

    Nutrients

    2019  Volume 12, Issue 1

    Abstract: Alcohol has a hormetic physiological behavior that results in either increased or decreased cardiovascular risk depending on the amount consumed, drinking frequency, pattern of consumption, and the outcomes under study or even the type of alcoholic ... ...

    Abstract Alcohol has a hormetic physiological behavior that results in either increased or decreased cardiovascular risk depending on the amount consumed, drinking frequency, pattern of consumption, and the outcomes under study or even the type of alcoholic beverage consumed. However, the vast majority of studies elucidating the role of alcohol in cardiovascular and in the global burden of disease relies on epidemiological studies of associative nature which carry several limitations. This is why the cardiovascular benefits of low-moderate alcohol consumption are being questioned and perhaps might have been overestimated. Thus, the aim of this review was to critically discuss the current knowledge on the relationship between alcohol intake and cardiovascular disease. Besides new evidence associating low and moderate alcohol consumption with decreased risk of cardiovascular disease, several questions remain unanswered related to the concrete amount of safe consumption, the type of alcoholic beverage, and the age-, sex-, and genetic/ethnical-specific differences in alcohol consumption.
    MeSH term(s) Adult ; Alcohol Drinking ; Alcoholic Beverages ; Alcoholism/blood ; Amino Acids, Essential/administration & dosage ; Body Composition ; Cardiovascular Diseases/prevention & control ; Female ; Humans ; Lipids/blood ; Male ; Middle Aged ; Risk Factors ; Young Adult
    Chemical Substances Amino Acids, Essential ; Lipids
    Language English
    Publishing date 2019-12-30
    Publishing country Switzerland
    Document type Clinical Trial ; Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu12010108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Cross-Talk between Lipoproteins and Inflammation: The Role of Microvesicles.

    Chiva-Blanch, Gemma / Badimon, Lina

    Journal of clinical medicine

    2019  Volume 8, Issue 12

    Abstract: Atherothrombosis is the principal underlying cause of cardiovascular disease (CVD). Microvesicles (MV) are small blebs originated by an outward budding at the cell plasma membranes, which are released in normal conditions. However, MV release is ... ...

    Abstract Atherothrombosis is the principal underlying cause of cardiovascular disease (CVD). Microvesicles (MV) are small blebs originated by an outward budding at the cell plasma membranes, which are released in normal conditions. However, MV release is increased in pathophysiologic conditions such as CVD. Low density lipoprotein (LDL) and MV contribute to atherothrombosis onset and progression by promoting inflammation and leukocyte recruitment to injured endothelium, as well as by increasing thrombosis and plaque vulnerability. Moreover, (oxidized)LDL induces MV release and vice-versa, perpetuating endothelium injury leading to CVD progression. Therefore, MV and lipoproteins exhibit common features, which should be considered in the interpretation of their respective roles in the pathophysiology of CVD. Understanding the pathways implicated in this process will aid in developing novel therapeutic approaches against atherothrombosis.
    Language English
    Publishing date 2019-11-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm8122059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Relevance of sex-differenced analyses in bioenergetics and nutritional studies.

    Garrabou, Glòria / García-García, Francesc Josep / Presmanes, Rosa Elvira / Feu, Maria / Chiva-Blanch, Gemma

    Frontiers in nutrition

    2022  Volume 9, Page(s) 936929

    Abstract: Sex-biased analyses still remain as one of the biggest limitations to obtain universal conclusions. In biomedicine, the majority of experimental analyses and a significant amount of patient-derived cohort studies exclusively included males. In ... ...

    Abstract Sex-biased analyses still remain as one of the biggest limitations to obtain universal conclusions. In biomedicine, the majority of experimental analyses and a significant amount of patient-derived cohort studies exclusively included males. In nutritional and molecular medicine, sex-influence is also frequently underrated, even considering maternal-inherited organelles such as mitochondria. We herein illustrate with in-house original data examples of how sex influences mitochondrial homeostasis, review these topics and highlight the consequences of biasing scientific analyses excluding females as differentiated entities from males.
    Language English
    Publishing date 2022-09-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2022.936929
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Effects of Polyphenol Intake on Metabolic Syndrome: Current Evidences from Human Trials.

    Chiva-Blanch, Gemma / Badimon, Lina

    Oxidative medicine and cellular longevity

    2017  Volume 2017, Page(s) 5812401

    Abstract: Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors which severely increases the risk of type II diabetes and cardiovascular disease. Several epidemiological studies have observed a negative association between polyphenol intake and ... ...

    Abstract Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors which severely increases the risk of type II diabetes and cardiovascular disease. Several epidemiological studies have observed a negative association between polyphenol intake and MetS rates. Nevertheless, there are relatively small numbers of interventional studies evidencing this association. This review is focused on human interventional trials with polyphenols as polyphenol-rich foods and dietary patterns rich in polyphenols in patients with MetS. Current evidence suggests that polyphenol intake has the potential to alleviate MetS components by decreasing body weight, blood pressure, and blood glucose and by improving lipid metabolism. Therefore, high intake of polyphenol-rich foods such as nuts, fruits, vegetables, seasoning with aromatic plants, spices, and virgin olive oil may be the cornerstone of a healthy diet preventing the development and progression of MetS, although there is no polyphenol or polyphenol-rich food able to influence all MetS features. However, inconsistent results have been found in different trials, and more long-term randomized trials are warranted to develop public health strategies to decrease MetS rates.
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1942-0994
    ISSN (online) 1942-0994
    DOI 10.1155/2017/5812401
    Database MEDical Literature Analysis and Retrieval System OnLINE

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