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  1. Article ; Online: NADH-Reductive Stress in Cancer Cell Proliferation.

    Choi, Dahee

    Molecules and cells

    2023  Volume 46, Issue 8, Page(s) 473–475

    MeSH term(s) Humans ; NAD ; Neoplasms
    Chemical Substances NAD (0U46U6E8UK)
    Language English
    Publishing date 2023-08-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1148964-9
    ISSN 0219-1032 ; 1016-8478
    ISSN (online) 0219-1032
    ISSN 1016-8478
    DOI 10.14348/molcells.2023.0094
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4713: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Expressions of Gonadotropin Subunit Genes in the Reproductively Inactive Golden Hamsters.

    Choi, Donchan

    Development & reproduction

    2022  Volume 26, Issue 2, Page(s) 37–47

    Abstract: Photoperiod has well been established to regulate testicular activities in golden hamsters. These animals breed actively around summer but become infertile in winter. In males, testicles are full of multistep germ cells including spermatozoa in summer. ... ...

    Abstract Photoperiod has well been established to regulate testicular activities in golden hamsters. These animals breed actively around summer but become infertile in winter. In males, testicles are full of multistep germ cells including spermatozoa in summer. But in winter only fundamental cells consisting of the testicles are detected. The testicular degeneration is accompanied by the reduced levels of blood gonadotropins and testosterone. In this study, the expressions of gonadotropin subunit genes were investigated in the reproductive active and inactive testicles. And parts of sequences of the gonadotropin subunits were identified and compared with those of other rodents. As results, common gonadotropin alpha (CGa), follicle-stimulating hormone (FSH) β, and luteinizing hormone (LH) β genes were equivalently detected in pituitaries of both sexually active and inactive animals. In considering low concentrations of gonadotropin hormones determined in pituitary, the present findings imply that the processes involved in translation and/or formation of functional hormones could be impeded in the sexually inactive hamsters. All the nucleotide sequences of gonadotropin subunits identified in this study were same as those reported previously except for one base in CGa. An unsure amino acid deduced from the CGa sequence was confirmed from mRNA sequencing. The outcomes mentioned above suggest that animals with regressed testes prepare for the sexually active period forthcoming in the future.
    Language English
    Publishing date 2022-06-30
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3018107-0
    ISSN 2465-9541 ; 2465-9525
    ISSN (online) 2465-9541
    ISSN 2465-9525
    DOI 10.12717/DR.2022.26.2.37
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Electrochemical Analysis of Polymer Membrane with Inorganic Nanoparticles for High-Temperature PEM Fuel Cells.

    Choi, DongWoong

    Membranes

    2022  Volume 12, Issue 7

    Abstract: In order to solve the challenge that battery performance rapidly deteriorates at a high temperature condition of 100 °C or higher, ... ...

    Abstract In order to solve the challenge that battery performance rapidly deteriorates at a high temperature condition of 100 °C or higher, ZrO
    Language English
    Publishing date 2022-06-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2614641-1
    ISSN 2077-0375
    ISSN 2077-0375
    DOI 10.3390/membranes12070680
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The Transmittance Modulation of ZnO/Cu/ZnO Transparent Conductive Electrodes Prepared on Glass Substrates.

    Choi, Dooho

    Materials (Basel, Switzerland)

    2020  Volume 13, Issue 18

    Abstract: With the explosive development of optoelectronic devices, the need for high-performance transparent conductive (TCE) electrodes for optoelectronic devices has been increasing accordingly. The two major TCE requirements are (1) visible light average ... ...

    Abstract With the explosive development of optoelectronic devices, the need for high-performance transparent conductive (TCE) electrodes for optoelectronic devices has been increasing accordingly. The two major TCE requirements are (1) visible light average transmittance higher than 80% and (2) sheet resistance lower than 10 Ω/sq. In this study, we investigated the critical role of the top and bottom ZnO thicknesses for the ZnO/Cu/ZnO electrodes prepared on glass substrates. It was shown that the required Cu thickness to meet the conductivity requirement is 8 nm, which was fixed and then the thicknesses of the top and ZnO layers were independently varied to experimentally determine the optimized conditions for optical transparency. The thicknesses of the top and bottom ZnO layers were both found to significantly affect the peak transmittance as well as the average visible light transmittance. The ZnO/Cu/ZnO electrode exhibits peak and average transmittance of 95.4% and 87.4%, excluding the transmittance of glass substrates, along with a sheet resistance of 9.7 Ω/sq, with a corresponding Haacke's figure of merit (φH=Tave10Rs) of 0.064, which exceeds the reported value for the ZnO/Cu/ZnO electrodes, manifesting the need of experimental optimization in this study.
    Language English
    Publishing date 2020-09-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma13183916
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  5. Article: LysGR1, a novel thermostable endolysin from

    Choi, Dahee / Kong, Minsuk

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1178748

    Abstract: Geobacillus ... ...

    Abstract Geobacillus stearothermophilus
    Language English
    Publishing date 2023-05-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1178748
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Cancel cancer: The immunotherapeutic potential of CD200/CD200R blockade.

    Choe, Deborah / Choi, Dongwon

    Frontiers in oncology

    2023  Volume 13, Page(s) 1088038

    Abstract: Immune checkpoint molecules function to inhibit and regulate immune response pathways to prevent hyperactive immune activity from damaging healthy tissues. In cancer patients, targeting these key molecules may serve as a valuable therapeutic mechanism to ...

    Abstract Immune checkpoint molecules function to inhibit and regulate immune response pathways to prevent hyperactive immune activity from damaging healthy tissues. In cancer patients, targeting these key molecules may serve as a valuable therapeutic mechanism to bolster immune function and restore the body's natural defenses against tumors. CD200, an immune checkpoint molecule, is a surface glycoprotein that is widely but not ubiquitously expressed throughout the body. By interacting with its inhibitory receptor CD200R, CD200 suppresses immune cell activity within the tumor microenvironment, creating conditions that foster tumor growth. Targeting the CD200/CD200R pathway, either through the use of monoclonal antibodies or peptide inhibitors, has shown to be effective in boosting anti-tumor immune activity. This review will explore CD200 and the protein's expression and role within the tumor microenvironment, blood endothelial cells, and lymph nodes. This paper will also discuss the advantages and challenges of current strategies used to target CD200 and briefly summarize relevant preclinical/clinical studies investigating the immunotherapeutic efficacy of CD200/CD200R blockade.
    Language English
    Publishing date 2023-01-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1088038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Quantitative Analysis of RNA Polymerase Slippages for Production of P3N-PIPO Trans-frame Fusion Proteins in Potyvirids.

    Choi, Dongjin / Hahn, Yoonsoo

    Journal of microbiology (Seoul, Korea)

    2023  Volume 61, Issue 10, Page(s) 917–927

    Abstract: Potyvirids, members of the family Potyviridae, produce the P3N-PIPO protein, which is crucial for the cell-to-cell transport of viral genomic RNAs. The production of P3N-PIPO requires an adenine (A) insertion caused by RNA polymerase slippage at a ... ...

    Abstract Potyvirids, members of the family Potyviridae, produce the P3N-PIPO protein, which is crucial for the cell-to-cell transport of viral genomic RNAs. The production of P3N-PIPO requires an adenine (A) insertion caused by RNA polymerase slippage at a conserved GAAAAAA (GA
    MeSH term(s) Viral Proteins/genetics ; Viral Proteins/metabolism ; DNA-Directed RNA Polymerases/genetics ; Potyvirus/genetics ; Potyvirus/metabolism ; Genome, Viral ; Open Reading Frames ; RNA, Plant ; RNA, Viral/genetics ; Plant Diseases ; Phylogeny
    Chemical Substances Viral Proteins ; DNA-Directed RNA Polymerases (EC 2.7.7.6) ; RNA, Plant ; RNA, Viral
    Language English
    Publishing date 2023-10-16
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2012399-1
    ISSN 1976-3794 ; 1225-8873
    ISSN (online) 1976-3794
    ISSN 1225-8873
    DOI 10.1007/s12275-023-00083-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5211: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: CT findings of inferior vena cava trauma according to the level of injury: a retrospective analysis of 19 cases in a single trauma centre.

    Choi, D / Choi, S H / Jung, H / Kim, J

    Clinical radiology

    2023  Volume 79, Issue 1, Page(s) e182–e188

    Abstract: Aim: To analyse the clinicoradiological characteristics of traumatic inferior vena cava (IVC) injury level on preoperative computed tomography (CT).: Materials and methods: This retrospective study evaluated patients from a single trauma centre ... ...

    Abstract Aim: To analyse the clinicoradiological characteristics of traumatic inferior vena cava (IVC) injury level on preoperative computed tomography (CT).
    Materials and methods: This retrospective study evaluated patients from a single trauma centre treated for traumatic IVC injury between January 2014 and January 2021. Data on demographics, mechanism of injury, Injury Severity Score, radiological findings on CT and angiography, IVC injury level in surgical findings, complications, and clinical outcomes were collected.
    Results: During the 8-year study period, 36 patients presented with traumatic IVC injury: 19 underwent preoperative CT with 17 (89%) blunt and two (11%) penetrating injuries. The most common primary CT sign was contour abnormality (53%, n=10), followed by intraluminal flap and active extravasation (21%, n=4). Among the secondary signs, hepatic laceration (53%, n=10) and retroperitoneal haemorrhage (53%, n=10) were the most common. Frequencies of primary and secondary signs were higher in the infrarenal and suprarenal than in the retrohepatic vena cava injuries. Diagnostic capability of preoperative CT for IVC injury differed according to the IVC level. The detection rate was the highest for an infrarenal vena cava injury at 100% (n=4), followed by that for a suprarenal, suprahepatic, and retrohepatic vena cava injuries at 75% (n=3), 43% (n=3), and 25% (n=1), respectively.
    Conclusion: CT findings of traumatic IVC injuries may vary depending on the mechanism and anatomical site of injury. Familiarity with IVC injury imaging features may help in diagnosis and surgical treatment planning.
    MeSH term(s) Humans ; Vena Cava, Inferior/diagnostic imaging ; Vena Cava, Inferior/injuries ; Retrospective Studies ; Trauma Centers ; Liver/diagnostic imaging ; Vascular System Injuries/diagnostic imaging ; Tomography, X-Ray Computed ; Abdominal Injuries
    Language English
    Publishing date 2023-10-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 391227-9
    ISSN 1365-229X ; 0009-9260
    ISSN (online) 1365-229X
    ISSN 0009-9260
    DOI 10.1016/j.crad.2023.10.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.201: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article: Successful Treatment of Eosinophilic Enterocolitis in an Adult Patient With Adalimumab.

    Fu, Yichun / Choi, David / Ronen, Natali / Dalal, Sushila

    ACG case reports journal

    2024  Volume 11, Issue 2, Page(s) e01285

    Abstract: Eosinophilic gastrointestinal diseases are increasing in prevalence, but understanding of their causes and effective treatments remain elusive, especially in adults. We present a case of eosinophilic gastroenteritis and colitis with extraintestinal ... ...

    Abstract Eosinophilic gastrointestinal diseases are increasing in prevalence, but understanding of their causes and effective treatments remain elusive, especially in adults. We present a case of eosinophilic gastroenteritis and colitis with extraintestinal manifestations that was successfully treated with a tumor necrosis factor α inhibitor, adalimumab.
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000001285
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Effects of Dietary Supplement Containing Melatonin on Reproductive Activity in Male Golden Hamsters.

    Choi, Donchan

    Development & reproduction

    2019  Volume 23, Issue 2, Page(s) 101–110

    Abstract: Melatonin is a pineal hormone that is synthesized and released at night under the light and dark cycles of a day. Its effects on the reproductive activities have well been established by the administration through various routes in photoperiodic animals. ...

    Abstract Melatonin is a pineal hormone that is synthesized and released at night under the light and dark cycles of a day. Its effects on the reproductive activities have well been established by the administration through various routes in photoperiodic animals. It was also identified in plants and named phytomelatonin. The capacity of the phytomelatonin was investigated in this investigation whether it affects the reproductive function in male golden hamster. As expected, animals housed in long photoperiod (long photoperiod, LP>12.5 hours of lights in a day) had large testes and animals kept in short photoperiod (SP≦12.5 hours of lights in a day) showed remarkably reduced testes. The dietary supplement with melatonin itself induced the complete involution of testes. Pistachios that were reported to contain a large amount of melatonin demonstrated no effects at all in male golden hamsters. These results suggest that dietary supplement containing melatonin-rich foodstuff used in this investigation may not be enough to affect the reproductive endocrine system in male golden hamsters.
    Language English
    Publishing date 2019-06-30
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3018107-0
    ISSN 2465-9541 ; 2465-9525
    ISSN (online) 2465-9541
    ISSN 2465-9525
    DOI 10.12717/DR.2019.23.2.101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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