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  1. AU="Choi, John Kim"
  2. AU="Streng, Bianca M M"
  3. AU="Franklin, Renty B"
  4. AU="Tetri, Laura H"
  5. AU="Badve, Sunil V"
  6. AU=Zhang Yinan
  7. AU="Piquero, Nicole Leeper"
  8. AU="Russo, Giorgio Ivan" AU="Russo, Giorgio Ivan"
  9. AU=Pourdowlat Guitti
  10. AU="Frisenda, Riccardo"
  11. AU=Palmucci Stefano

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  1. Artikel ; Online: Laboratory Aspects of Minimal / Measurable Residual Disease Testing in B-Lymphoblastic Leukemia.

    Choi, John Kim / Mead, Paul E

    Clinics in laboratory medicine

    2023  Band 43, Heft 1, Seite(n) 115–125

    Abstract: Minimal residual disease detection provides critical prognostic predictor of treatment outcome and is the standard of care for B lymphoblastic leukemia. Flow cytometry-based minimal residual disease detection is the most common test modality and has high ...

    Abstract Minimal residual disease detection provides critical prognostic predictor of treatment outcome and is the standard of care for B lymphoblastic leukemia. Flow cytometry-based minimal residual disease detection is the most common test modality and has high sensitivity (0.01%) and a rapid turnaround time (24 hours). This article details the leukemia associated immunophenotype analysis approach for flow cytometry-based minimal residual disease detection used at St. Jude Children's Research Hospital and importance of using guide gates and back-gating.
    Mesh-Begriff(e) Child ; Humans ; Neoplasm, Residual/diagnosis ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/diagnosis ; Treatment Outcome ; Prognosis ; Flow Cytometry
    Sprache Englisch
    Erscheinungsdatum 2023-02-09
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 604580-7
    ISSN 1557-9832 ; 0272-2712
    ISSN (online) 1557-9832
    ISSN 0272-2712
    DOI 10.1016/j.cll.2022.09.022
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Laboratory Aspects of Minimal / Measurable Residual Disease Testing in B-Lymphoblastic Leukemia.

    Choi, John Kim / Mead, Paul E

    Clinics in laboratory medicine

    2021  Band 41, Heft 3, Seite(n) 485–495

    Abstract: Minimal residual disease detection provides critical prognostic predictor of treatment outcome and is the standard of care for B lymphoblastic leukemia. Flow cytometry-based minimal residual disease detection is the most common test modality and has high ...

    Abstract Minimal residual disease detection provides critical prognostic predictor of treatment outcome and is the standard of care for B lymphoblastic leukemia. Flow cytometry-based minimal residual disease detection is the most common test modality and has high sensitivity (0.01%) and a rapid turnaround time (24 hours). This article details the leukemia associated immunophenotype analysis approach for flow cytometry-based minimal residual disease detection used at St. Jude Children's Research Hospital and importance of using guide gates and back-gating.
    Mesh-Begriff(e) Child ; Flow Cytometry ; Humans ; Immunophenotyping ; Laboratories ; Neoplasm, Residual ; Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Sprache Englisch
    Erscheinungsdatum 2021-07-01
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 604580-7
    ISSN 1557-9832 ; 0272-2712
    ISSN (online) 1557-9832
    ISSN 0272-2712
    DOI 10.1016/j.cll.2021.03.013
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Mixed-phenotype acute leukemia, T/megakaryoblastic.

    Klairmont, Matthew M / Choi, John Kim

    Blood

    2018  Band 132, Heft 22, Seite(n) 2418

    Mesh-Begriff(e) Antigens, CD/analysis ; Bone Marrow/pathology ; Female ; Humans ; Infant, Newborn ; Leukemia, Megakaryoblastic, Acute/complications ; Leukemia, Megakaryoblastic, Acute/genetics ; Leukemia, Megakaryoblastic, Acute/pathology ; Leukemia, Megakaryoblastic, Acute/therapy ; Lymphocytes/pathology ; Male ; Megakaryocyte Progenitor Cells/pathology ; Phenotype ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/therapy ; Stem Cell Transplantation ; T-Lymphocytes/pathology
    Chemische Substanzen Antigens, CD
    Sprache Englisch
    Erscheinungsdatum 2018-11-29
    Erscheinungsland United States
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood-2018-09-871194
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: CD30 Expression in Pediatric Neoplasms, Study of 585 Cases.

    Cheng, Jinjun / Zhu, Haiqing / Choi, John Kim

    Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society

    2017  Band 20, Heft 3, Seite(n) 191–196

    Abstract: CD30 is a member of the tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), and its normal expression is restricted to activated T and B cells. In tumor cells, CD30 expression is most commonly associated with lymphoid malignancies (Hodgkin ... ...

    Abstract CD30 is a member of the tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), and its normal expression is restricted to activated T and B cells. In tumor cells, CD30 expression is most commonly associated with lymphoid malignancies (Hodgkin and non-Hodgkin lymphomas) and is a therapeutic target using anti-CD30 antibody. CD30 expression has been reported also in mostly adult non-lymphoid malignancies, raising the possibility of CD30-targeted therapy for additional tumors. In this study, we examined the incidence of CD30 expression in 251 hematopoietic and 334 non-hematopoietic cases of pediatric tumors. As expected, strong and membranous CD30 staining was seen in anaplastic large cell lymphoma, classical Hodgkin lymphoma, and embryonal carcinoma while variable staining was seen in diffuse large B cell lymphoma. In addition, positive CD30 staining was also seen in cases of neuroblastoma (33 of 56), neoplasm with chondroid differentiation (8 of 25), myeloid neoplasms (11 of 120), hemangioma (2 of 12), and mature teratoma (1 of 11). In neuroblastoma, the CD30 expression was generally restricted to cells with ganglion differentiation; staining of ganglion cells was also seen in the one positive case of mature teratoma. In neoplasm with chondroid differentiation, the positive cases were chondrosarcoma (3 of 5), chondroblastic osteosarcoma (2 of 10), and chondroblastoma (3 of 7). In acute myeloid leukemia, the CD30 positive cases were more common in AML with monocytic differentiation but did not correlate with any specific molecular change. We conclude that CD30 expression in pediatric tumors is more general than anticipated and future studies are warranted to understand the biologic and therapeutic significances.
    Mesh-Begriff(e) Child ; Humans ; Immunohistochemistry ; Ki-1 Antigen/metabolism ; Neoplasms/diagnosis ; Neoplasms/metabolism ; Neoplasms/therapy ; Retrospective Studies
    Chemische Substanzen Ki-1 Antigen
    Sprache Englisch
    Erscheinungsdatum 2017-02-08
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1463498-3
    ISSN 1615-5742 ; 1093-5266
    ISSN (online) 1615-5742
    ISSN 1093-5266
    DOI 10.1177/1093526616689185
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: The Comparative Sensitivity of Immunohistochemical Markers of Megakaryocytic Differentiation in Acute Megakaryoblastic Leukemia.

    Klairmont, Matthew M / Hoskoppal, Deepthi / Yadak, Nour / Choi, John Kim

    American journal of clinical pathology

    2018  Band 150, Heft 5, Seite(n) 461–467

    Abstract: Objectives: Immunohistochemistry (IHC) staining of core biopsy sections often plays an essential role in the diagnosis of acute megakaryoblastic leukemia (AMKL). The goal of this study was to define the relative sensitivities of commonly used stains for ...

    Abstract Objectives: Immunohistochemistry (IHC) staining of core biopsy sections often plays an essential role in the diagnosis of acute megakaryoblastic leukemia (AMKL). The goal of this study was to define the relative sensitivities of commonly used stains for markers of megakaryocytic differentiation.
    Methods: The sensitivities of IHC stains for CD42b, CD61, and von Willebrand factor (vWF) were compared in 32 cases of pediatric AMKL.
    Results: The sensitivities of CD42b, CD61, and vWF were 90.6%, 78.1% and 62.5%, respectively. When CD42b and CD61 were used together, the combined sensitivity increased to 93.6%. There were no cases in which vWF was positive when both CD42b and CD61 were negative.
    Conclusions: CD42b can reliably be used as a solitary first-line marker for blasts of megakaryocytic lineage, whereas CD61 may be reserved for infrequent cases that are CD42b negative. There is no role for the routine use of vWF when CD42b and CD61 are available.
    Mesh-Begriff(e) Biomarkers/metabolism ; Biopsy, Large-Core Needle ; Bone Marrow/metabolism ; Bone Marrow/pathology ; Cell Differentiation ; Child ; Humans ; Immunohistochemistry ; Integrin beta3/metabolism ; Leukemia, Megakaryoblastic, Acute/diagnosis ; Leukemia, Megakaryoblastic, Acute/metabolism ; Leukemia, Megakaryoblastic, Acute/pathology ; Megakaryocytes/metabolism ; Megakaryocytes/pathology ; Platelet Glycoprotein GPIb-IX Complex/metabolism ; Reagent Kits, Diagnostic ; Sensitivity and Specificity ; von Willebrand Factor/metabolism
    Chemische Substanzen Biomarkers ; Integrin beta3 ; Platelet Glycoprotein GPIb-IX Complex ; Reagent Kits, Diagnostic ; von Willebrand Factor
    Sprache Englisch
    Erscheinungsdatum 2018-07-26
    Erscheinungsland England
    Dokumenttyp Comparative Study ; Evaluation Study ; Journal Article
    ZDB-ID 2944-0
    ISSN 1943-7722 ; 0002-9173
    ISSN (online) 1943-7722
    ISSN 0002-9173
    DOI 10.1093/ajcp/aqy074
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Pediatric MLBL: challenges remain.

    Sandlund, John T / Choi, John Kim

    Blood

    2013  Band 121, Heft 2, Seite(n) 245–246

    Abstract: In this issue of Blood, Gerrard et al report the outcome and histologic classification of children and adolescents with mediastinal large B-cell lymphoma (MLBL), and highlight the need for new treatment strategies. ...

    Abstract In this issue of Blood, Gerrard et al report the outcome and histologic classification of children and adolescents with mediastinal large B-cell lymphoma (MLBL), and highlight the need for new treatment strategies.
    Mesh-Begriff(e) Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Female ; Humans ; Lymphoma, Large B-Cell, Diffuse/drug therapy ; Lymphoma, Large B-Cell, Diffuse/pathology ; Male ; Mediastinal Neoplasms/drug therapy ; Mediastinal Neoplasms/pathology
    Sprache Englisch
    Erscheinungsdatum 2013-01-10
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood-2012-11-468629
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Clinicopathologic and prognostic features of TdT-negative pediatric B-lymphoblastic leukemia.

    Klairmont, Matthew M / Zhou, Yinmei / Cheng, Cheng / Pui, Ching-Hon / Jeha, Sima / Gruber, Tanja A / Liu, Yiwei / Inaba, Hiroto / Choi, John Kim

    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

    2021  Band 34, Heft 11, Seite(n) 2050–2054

    Abstract: Little is known about B-lymphoblastic leukemia (B-ALL) that lacks expression of terminal deoxynucleotidyl transferase (TdT). To address this, we performed the largest study to date of TdT-negative B-ALL using data from St. Jude Total XV and XVI clinical ... ...

    Abstract Little is known about B-lymphoblastic leukemia (B-ALL) that lacks expression of terminal deoxynucleotidyl transferase (TdT). To address this, we performed the largest study to date of TdT-negative B-ALL using data from St. Jude Total XV and XVI clinical trials. Compared to TdT-positive B-ALL (n = 896), TdT-negative B-ALL (n = 21) was associated with younger age (median, 1.4 versus 6.8 years, P < 0.001), higher white blood cell count (median, 52.8 versus 9.9 × 10
    Mesh-Begriff(e) Adolescent ; Biomarkers, Tumor/metabolism ; Child ; Child, Preschool ; Cytogenetics ; DNA Nucleotidylexotransferase/metabolism ; Disease-Free Survival ; Female ; Flow Cytometry ; Gene Rearrangement ; Histone-Lysine N-Methyltransferase/genetics ; Humans ; Immunophenotyping ; Infant ; Leukocyte Count ; Male ; Myeloid-Lymphoid Leukemia Protein/genetics ; Neoplasm Proteins/genetics ; Nuclear Proteins/genetics ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/diagnosis ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/enzymology ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Prognosis ; Transcription Factors/genetics
    Chemische Substanzen Biomarkers, Tumor ; KMT2A protein, human ; MLLT1 protein, human ; Neoplasm Proteins ; Nuclear Proteins ; Transcription Factors ; Myeloid-Lymphoid Leukemia Protein (149025-06-9) ; Histone-Lysine N-Methyltransferase (EC 2.1.1.43) ; DNA Nucleotidylexotransferase (EC 2.7.7.31)
    Sprache Englisch
    Erscheinungsdatum 2021-06-19
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 645073-8
    ISSN 1530-0285 ; 0893-3952
    ISSN (online) 1530-0285
    ISSN 0893-3952
    DOI 10.1038/s41379-021-00853-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: α-Hemoglobin-stabilizing protein is a sensitive and specific marker of erythroid precursors.

    Raess, Philipp W / Paessler, Michelle E / Bagg, Adam / Weiss, Mitchell J / Choi, John Kim

    The American journal of surgical pathology

    2012  Band 36, Heft 10, Seite(n) 1538–1547

    Abstract: α-Hemoglobin-stabilizing protein (AHSP) is an abundant erythroid-specific chaperone protein that facilitates incorporation of nascent α-globin into hemoglobin A. We characterized AHSP expression by immunohistochemistry in a panel of 100 neoplastic and ... ...

    Abstract α-Hemoglobin-stabilizing protein (AHSP) is an abundant erythroid-specific chaperone protein that facilitates incorporation of nascent α-globin into hemoglobin A. We characterized AHSP expression by immunohistochemistry in a panel of 100 neoplastic and reactive bone marrow biopsies and splenic tissue with extramedullary hematopoiesis and compared it with established erythroid markers CD71 and CD235a. In all cases, AHSP expression was limited to physiological nucleated erythroid precursors (EPs) and blasts in erythroid leukemias. Although CD71 also stained EPs, it additionally stained nonerythroid malignant cells to varying extents in acute leukemia, diffuse large B-cell lymphoma, metastatic carcinomas, and small round blue cell tumors. In contrast, CD235a staining was erythroid-specific but stained non-nucleated red blood cells in all specimens, limiting its utility. We conclude that AHSP is superior to CD71 and CD235a for detecting normal and neoplastic nucleated EPs.
    Mesh-Begriff(e) Antigens, CD/metabolism ; Biomarkers, Tumor/metabolism ; Blood Proteins/metabolism ; Bone Marrow Cells/metabolism ; Bone Marrow Cells/pathology ; Erythroid Precursor Cells/metabolism ; Erythroid Precursor Cells/pathology ; Glycophorins/immunology ; Glycophorins/metabolism ; Immunohistochemistry/methods ; Leukemia, Erythroblastic, Acute/diagnosis ; Leukemia, Erythroblastic, Acute/metabolism ; Molecular Chaperones/metabolism ; Myelodysplastic-Myeloproliferative Diseases/diagnosis ; Myelodysplastic-Myeloproliferative Diseases/metabolism ; Neoplasms/diagnosis ; Neoplasms/metabolism ; Predictive Value of Tests ; Receptors, Transferrin/metabolism
    Chemische Substanzen AHSP protein, human ; Antigens, CD ; Biomarkers, Tumor ; Blood Proteins ; CD71 antigen ; Glycophorins ; Molecular Chaperones ; Receptors, Transferrin
    Sprache Englisch
    Erscheinungsdatum 2012-09-13
    Erscheinungsland United States
    Dokumenttyp Comparative Study ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 752964-8
    ISSN 1532-0979 ; 0147-5185
    ISSN (online) 1532-0979
    ISSN 0147-5185
    DOI 10.1097/PAS.0b013e31825fa501
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Prognostic Significance of Major Histocompatibility Complex Class II Expression in Pediatric Adrenocortical Tumors: A St. Jude and Children's Oncology Group Study.

    Pinto, Emilia Modolo / Rodriguez-Galindo, Carlos / Choi, John Kim / Pounds, Stanley / Liu, Zhifa / Neale, Geoffrey / Finkelstein, David / Hicks, John M / Pappo, Alberto S / Figueiredo, Bonald C / Ribeiro, Raul C / Zambetti, Gerard P

    Clinical cancer research : an official journal of the American Association for Cancer Research

    2016  Band 22, Heft 24, Seite(n) 6247–6255

    Abstract: Purpose: Histologic markers that differentiate benign and malignant pediatric adrenocortical tumors are lacking. Previous studies have implicated an association of MHC class II expression with adrenocortical tumor prognosis. Here, we determined the ... ...

    Abstract Purpose: Histologic markers that differentiate benign and malignant pediatric adrenocortical tumors are lacking. Previous studies have implicated an association of MHC class II expression with adrenocortical tumor prognosis. Here, we determined the expression of MHC class II as well as the cell of origin of these immunologic markers in pediatric adrenocortical tumor. The impact of MHC class II gene expression on outcome was determined in a cohort of uniformly treated children with adrenocortical carcinomas.
    Experimental design: We analyzed the expression of MHC class II and a selected cluster of differentiation genes in 63 pediatric adrenocortical tumors by Affymetrix Human U133 Plus 2.0 or HT HG-U133+PM gene chip analyses. Cells expressing MHC class II were identified by morphologic and immunohistochemical assays.
    Results: MHC class II expression was significantly greater in adrenocortical adenomas than in carcinomas (P = 4.8 ×10
    Conclusions: MHC class II expression, which is produced by tumor-infiltrating immune cells, is an indicator of disease aggressiveness in pediatric adrenocortical tumor. Our results suggest that immune responses modulate adrenocortical tumorigenesis and may allow the refinement of risk stratification and treatment for this disease. Clin Cancer Res; 22(24); 6247-55. ©2016 AACR.
    Sprache Englisch
    Erscheinungsdatum 2016-12-15
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1225457-5
    ISSN 1557-3265 ; 1078-0432
    ISSN (online) 1557-3265
    ISSN 1078-0432
    DOI 10.1158/1078-0432.CCR-15-2738
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Biologic and clinical features of childhood gamma delta T-ALL: identification of STAG2/LMO2 γδ T-ALL as an extremely high risk leukemia in the very young.

    Kimura, Shunsuke / Polonen, Petri / Montefiori, Lindsey / Park, Chun Shik / Iacobucci, Ilaria / Yeoh, Allen Ej / Attarbaschi, Andishe / Moore, Andrew S / Brown, Anthony / Manabe, Atsushi / Buldini, Barbara / Freeman, Burgess B / Chen, Chelsey / Cheng, Cheng / Kean Hui, Chiew / Li, Chi-Kong / Pui, Ching-Hon / Qu, Chunxu / Tomizawa, Daisuke /
    Teachey, David T / Varotto, Elena / Paietta, Elisabeth M / Arnold, Elizabeth D / Locatelli, Franco / Escherich, Gabriele / Elisa Muhle, Hannah / Marquart, Hanne Vibeke / de Groot-Kruseman, Hester A / Rowe, Jacob M / Stary, Jan / Trka, Jan / Choi, John Kim / Meijerink, Jules P P / Yang, Jun J / Takita, Junko / Pawinska-Wasikowska, Katarzyna / Roberts, Kathryn G / Han, Katie / Caldwell, Kenneth J / Schmiegelow, Kjeld / Crews, Kristine R / Eguchi, Mariko / Schrappe, Martin / Zimmerman, Martin / Takagi, Masatoshi / Maybury, Mellissa / Svaton, Michael / Reiterova, Michaela / Kicinski, Michal / Prater, Mollie S / Kato, Motohiro / Reyes, Noemi / Spinelli, Orietta / Thomas, Paul / Mazilier, Pauline / Gao, Qingsong / Masetti, Riccardo / Kotecha, Rishi S / Pieters, Rob / Elitzur, Sarah / Luger, Selina M / Mitchell, Sharnise / Pruett-Miller, Shondra M / Shen, Shuhong / Jeha, Sima / Köhrer, Stefan / Kornblau, Steven M / Skoczeń, Szymon / Miyamura, Takako / Vincent, Tiffaney L / Imamura, Toshihiko / Conter, Valentino / Tang, Yanjing / Liu, Yen-Chun / Chang, Yunchao / Gu, Zhaohui / Cheng, Zhongshan / Yinmei, Zhou / Inaba, Hiroto / Mullighan, Charles G

    medRxiv : the preprint server for health sciences

    2023  

    Abstract: Purpose: Gamma delta T-cell receptor-positive acute lymphoblastic leukemia (γδ T-ALL) is a high-risk but poorly characterized disease.: Methods: We studied clinical features of 200 pediatric γδ T-ALL, and compared the prognosis of 93 cases to 1,067 ... ...

    Abstract Purpose: Gamma delta T-cell receptor-positive acute lymphoblastic leukemia (γδ T-ALL) is a high-risk but poorly characterized disease.
    Methods: We studied clinical features of 200 pediatric γδ T-ALL, and compared the prognosis of 93 cases to 1,067 protocol-matched non-γδ T-ALL. Genomic features were defined by transcriptome and genome sequencing. Experimental modeling was used to examine the mechanistic impacts of genomic alterations. Therapeutic vulnerabilities were identified by high throughput drug screening of cell lines and xenografts.
    Results: γδ T-ALL in children under three was extremely high-risk with 5-year event-free survival (33% v. 70% [age 3-<10] and 73% [age ≥10],
    Conclusion: γδ T-ALL in children under the age of three is extremely high-risk and enriched for
    Support: The authors are supported by the American and Lebanese Syrian Associated Charities of St Jude Children's Research Hospital, NCI grants R35 CA197695, P50 CA021765 (C.G.M.), the Henry Schueler 41&9 Foundation (C.G.M.), and a St. Baldrick's Foundation Robert J. Arceci Innovation Award (C.G.M.), Gabriella Miller Kids First X01HD100702 (D.T.T and C.G.M.) and R03CA256550 (D.T.T. and C.G.M.), F32 5F32CA254140 (L.M.), and a Garwood Postdoctoral Fellowship of the Hematological Malignancies Program of the St Jude Children's Research Hospital Comprehensive Cancer Center (S.K.). This project was supported by the National Cancer Institute of the National Institutes of Health under the following award numbers: U10CA180820, UG1CA189859, U24CA114766, U10CA180899, U10CA180866 and U24CA196173.
    Disclaimer: The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The funding agencies were not directly involved in the design of the study, gathering, analysis and interpretation of the data, writing of the manuscript, or decision to submit the manuscript for publication.
    Sprache Englisch
    Erscheinungsdatum 2023-11-08
    Erscheinungsland United States
    Dokumenttyp Preprint
    DOI 10.1101/2023.11.06.23298028
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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