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  1. Article ; Online: Relationship between prosthodontic status and nutritional intake in the elderly in Korea: National Health and Nutrition Examination Survey (NHANES IV).

    Choi, Y K / Park, D Y / Kim, Y

    International journal of dental hygiene

    2014  Volume 12, Issue 4, Page(s) 285–290

    Abstract: Objectives: Many health issues have been reported to be associated with poor nutritional status. We sought to examine the association between nutritional intake and oral health status in elderly people.: Methods: The association between perceived ... ...

    Abstract Objectives: Many health issues have been reported to be associated with poor nutritional status. We sought to examine the association between nutritional intake and oral health status in elderly people.
    Methods: The association between perceived disability in mastication and prosthodontic status was analysed using multiple logistic regression. Multiple linear regression was used to analyse the association between prosthodontic status and nutritional intake.
    Results: The elderly subjects with partial or full dentures reported chewing difficulties 1.62-fold more frequently (95% CI: 1.06-2.49) than those with natural teeth or a fixed prosthesis after adjusting for gender, TMD (temporomandibular disorder), household income and education level. Additionally, daily nutritional intakes of energy, protein, fat, ash, calcium, phosphorus and thiamine were decreased significantly in elderly with partial or full dentures compared with those with no prosthesis or with a fixed prosthesis (P < 0.05).
    Conclusions: Our findings underline oral health status and perceived disability in mastication are associated with dietary imbalances in the elderly. We suggest that the evaluation of patients' nutritional status should be considered as a part of an overall plan for dental hygiene care.
    MeSH term(s) Aged ; Calcium, Dietary/administration & dosage ; Dentition ; Denture, Complete ; Denture, Partial ; Dentures ; Dietary Fats/administration & dosage ; Dietary Proteins/administration & dosage ; Eating/physiology ; Educational Status ; Energy Intake ; Female ; Health Status ; Humans ; Income ; Male ; Mastication/physiology ; Nutrition Surveys ; Nutritional Status ; Oral Health ; Phosphorus/administration & dosage ; Republic of Korea ; Temporomandibular Joint Disorders/complications ; Thiamine/administration & dosage
    Chemical Substances Calcium, Dietary ; Dietary Fats ; Dietary Proteins ; Phosphorus (27YLU75U4W) ; Thiamine (X66NSO3N35)
    Language English
    Publishing date 2014-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2252118-5
    ISSN 1601-5037 ; 1601-5029
    ISSN (online) 1601-5037
    ISSN 1601-5029
    DOI 10.1111/idh.12066
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  2. Article: Shrink-wrapped isosurface from cross sectional images.

    Choi, Y K / Hahn, J K

    IEICE transactions on information and systems

    2010  Volume E90-D, Issue 12, Page(s) 2070–2076

    Abstract: This paper addresses a new surface reconstruction scheme for approximating the isosurface from a set of tomographic cross sectional images. Differently from the novel Marching Cubes (MC) algorithm, our method does not extract the iso-density surface ( ... ...

    Abstract This paper addresses a new surface reconstruction scheme for approximating the isosurface from a set of tomographic cross sectional images. Differently from the novel Marching Cubes (MC) algorithm, our method does not extract the iso-density surface (isosurface) directly from the voxel data but calculates the iso-density point (isopoint) first. After building a coarse initial mesh approximating the ideal isosurface by the cell-boundary representation, it metamorphoses the mesh into the final isosurface by a relaxation scheme, called shrink-wrapping process. Compared with the MC algorithm, our method is robust and does not make any cracks on surface. Furthermore, since it is possible to utilize lots of additional isopoints during the surface reconstruction process by extending the adjacency definition, theoretically the resulting surface can be better in quality than the MC algorithm. According to experiments, it is proved to be very robust and efficient for isosurface reconstruction from cross sectional images.
    Language English
    Publishing date 2010-07-12
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2214518-7
    ISSN 1745-1361 ; 0916-8532
    ISSN (online) 1745-1361
    ISSN 0916-8532
    DOI 10.1093/ietisy/e90-d.12.2070
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  3. Article ; Online: Present and Future Trends in Consumer Health Informatics and Patient-Generated Health Data.

    Lai, A M / Hsueh, P-Y S / Choi, Y K / Austin, R R

    Yearbook of medical informatics

    2017  Volume 26, Issue 1, Page(s) 152–159

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) Consumer Health Informatics/trends ; Health Records, Personal ; Humans ; Information Seeking Behavior ; Professional-Patient Relations ; Telemedicine
    Language English
    Publishing date 2017-09-11
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2251229-9
    ISSN 2364-0502 ; 2364-0502
    ISSN (online) 2364-0502
    ISSN 2364-0502
    DOI 10.15265/IY-2017-016
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  4. Article ; Online: Demetylation of the sex-determining region Y gene promoter and incidence of disorder of sex development in cloned dog males.

    Hwang, K C / Choi, Y K / Jeong, Y I / Park, K B / Choi, E J / Jeong, Y W / Hossein, M S / Hyun, S H / Jeung, E-B / Hwang, W S

    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society

    2020  Volume 71, Issue 3

    Abstract: Canine cloning is occasionally accompanied by abnormal sexual development. Some male donor cells produce cloned pups with female external genitalia and complete male gonadal dysgenesis, which is classified as an XY disorder of sex development (XY DSD). ... ...

    Abstract Canine cloning is occasionally accompanied by abnormal sexual development. Some male donor cells produce cloned pups with female external genitalia and complete male gonadal dysgenesis, which is classified as an XY disorder of sex development (XY DSD). In this study, we examine the potential of 5-aza-2'-deoxycytidine (5-aza-dC), a DNA methyltransferase inhibitor, to reduce the phenotypic abnormality XY DSD in somatic cell nuclear transfer (SCNT)- derived pups. We used a 9-year-old normal male German Shepherd dog as a cell donor. Donor cells were treated with 10 nM 5-aza-dC for 4 days before being used for SCNT. At the same stage of cell development, significantly lower levels of DNA methylation of the sex-determining region Y (SRY) promoter was observed in the treated donor cells compared to that in the untreated cells (95.2% versus 53.3% on day 4 for the control and treated groups, respectively). No significant differences were observed in the control or treatment groups concerning fusion rate, pregnancy rate (30 days or entire period), the number of pups, or the incidence of XY DSD. However, more XY DSD dogs were observed in the control group (31.25%) than in the treatment group (14.29%). Hypermethylation of the SRY promoter was observed in the XY DSD cloned pups in both the treatment (84.8%) and control groups (91.1 ± 1.4%) compared to the methylation level in the phenotypically normal male pups of the treatment (23.2 ± 20.9%) and control groups (39.1 ± 20.1%). These results suggest that 5-aza-dC treatment of donor cells can reduce the methylation level of the SRY promoter in donor cells, and thus, 5-aza-dC is advantageous for reducing the incidence of XY DSD in canine cloning.
    MeSH term(s) Animals ; Cloning, Molecular ; DNA Methylation/drug effects ; DNA Modification Methylases/antagonists & inhibitors ; DNA Modification Methylases/metabolism ; Decitabine/pharmacology ; Dog Diseases/drug therapy ; Dog Diseases/genetics ; Dog Diseases/pathology ; Dogs ; Enzyme Inhibitors/pharmacology ; Genetic Predisposition to Disease ; Gonadal Dysgenesis, 46,XY/drug therapy ; Gonadal Dysgenesis, 46,XY/genetics ; Gonadal Dysgenesis, 46,XY/pathology ; Gonadal Dysgenesis, 46,XY/veterinary ; Male ; Nuclear Transfer Techniques/adverse effects ; Nuclear Transfer Techniques/veterinary ; Phenotype ; Promoter Regions, Genetic/drug effects ; Sex Determination Processes/genetics ; Sex-Determining Region Y Protein/genetics
    Chemical Substances Enzyme Inhibitors ; Sex-Determining Region Y Protein ; Decitabine (776B62CQ27) ; DNA Modification Methylases (EC 2.1.1.-)
    Language English
    Publishing date 2020-09-26
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 1125221-2
    ISSN 1899-1505 ; 0867-5910 ; 0044-6033
    ISSN (online) 1899-1505
    ISSN 0867-5910 ; 0044-6033
    DOI 10.26402/jpp.2020.3.05
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  5. Article: Implementation of secondary stroke prevention protocol for ischaemic stroke patients in primary care.

    Choi, Y K / Han, J H / Li, Richard / Kung, Kenny / Lam, Augustine

    Hong Kong medical journal = Xianggang yi xue za zhi

    2015  Volume 21, Issue 2, Page(s) 136–142

    Abstract: Objective: To investigate the effectiveness of a secondary stroke prevention protocol in the general out-patient clinic.: Design: Cohort study with pre- and post-intervention comparisons.: Setting: Two general out-patient clinics in Hong Kong.: ... ...

    Abstract Objective: To investigate the effectiveness of a secondary stroke prevention protocol in the general out-patient clinic.
    Design: Cohort study with pre- and post-intervention comparisons.
    Setting: Two general out-patient clinics in Hong Kong.
    Patients: Ischaemic stroke patients who had long-term follow-up in two clinics were recruited. The patients of one clinic received the intervention (intervention group) and the patients of the second clinic did not receive the intervention (control group). The recruitment period lasted for 6 months from 1 September 2008 to 28 February 2009. The pre-intervention phase data collection started within this 6-month period. The protocol implementation started at the intervention clinic on 1 April 2009. The post-intervention phase data collection started 9 months after the protocol implementation, and ran for 6 months from 1 January 2010 to 30 June 2010.
    Main outcome measures: Clinical data before and after the intervention, including blood pressure, glycated haemoglobin level, low-density lipoprotein level and prescription pattern, were compared between the two groups to see whether there was enhancement of secondary stroke management.
    Results: A total of 328 patients were recruited into the intervention group and 249 into the control group; data of 256 and 210 patients from these groups were analysed, respectively. After intervention, there were significant reductions in mean (± standard deviation) systolic blood pressure (135.2 ± 17.5 mm Hg to 127.7 ± 12.2 mm Hg), glycated haemoglobin level (7.2 ± 1.0% to 6.5 ± 0.8%), and low-density lipoprotein level (3.4 ± 0.8 mmol/L to 2.8 ± 1.3 mmol/L) in the intervention group (all P<0.01). There were no significant reductions in mean systolic blood pressure, glycated haemoglobin level, or low-density lipoprotein level in the control group. There was a significant increase in statin use (P<0.01) in both clinics.
    Conclusion: Through implementation of a clinic protocol, the standard of care of secondary stroke prevention for ischaemic stroke patients could be improved in a general out-patient clinic.
    MeSH term(s) Aged ; Ambulatory Care Facilities ; Brain Ischemia/diagnosis ; Brain Ischemia/prevention & control ; Brain Ischemia/therapy ; Clinical Protocols/standards ; Cohort Studies ; Female ; Follow-Up Studies ; Health Plan Implementation ; Hong Kong ; Humans ; Male ; Middle Aged ; Patient Care Team/organization & administration ; Primary Health Care/methods ; Prospective Studies ; Reference Values ; Risk Assessment ; Secondary Prevention/methods ; Stroke/diagnosis ; Stroke/prevention & control ; Stroke/therapy ; Survival Rate ; Treatment Outcome
    Language English
    Publishing date 2015-04
    Publishing country China
    Document type Comparative Study ; Journal Article
    ZDB-ID 1239255-8
    ISSN 1024-2708
    ISSN 1024-2708
    DOI 10.12809/hkmj144236
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  6. Article: Present and Future Trends in Consumer Health Informatics and Patient-Generated Health Data

    Lai, A. M. / Hsueh, P.-Y. S. / Choi, Y. K. / Austin, R. R.

    Yearbook of Medical Informatics

    2017  Volume 26, Issue 01, Page(s) 152–159

    Abstract: Objectives: Consumer Health Informatics (CHI) and the use of Patient-Generated Health Data (PGHD) are rapidly growing focus areas in healthcare. The objective of this paper is to briefly review the literature that has been published over the past few ... ...

    Abstract Objectives: Consumer Health Informatics (CHI) and the use of Patient-Generated Health Data (PGHD) are rapidly growing focus areas in healthcare. The objective of this paper is to briefly review the literature that has been published over the past few years and to provide a sense of where the field is going.
    Methods: We searched PubMed and the ACM Digital Library for articles published between 2014 and 2016 on the topics of CHI and PGHD. The results of the search were screened for relevance and categorized into a set of common themes. We discuss the major topics covered in these articles.
    Results: We retrieved 65 articles from our PubMed query and 32 articles from our ACM Digital Library query. After a review of titles, we were left with 47 articles to conduct our full article survey of the activities in CHI and PGHD. We have summarized these articles and placed them into major categories of activity. Within the domain of consumer health informatics, articles focused on mobile health and patient-generated health data comprise the majority of the articles published in recent years.
    Conclusions: Current evidence indicates that technological advancements and the widespread availability of affordable consumer-grade devices are fueling research into using PGHD for better care. As we observe a growing number of (pilot) developments using various mobile health technologies to collect PGHD, major gaps still exist in how to use the data by both patients and providers. Further research is needed to understand the impact of PGHD on clinical outcomes.
    Keywords Consumer health information/methods ; patient-generated health data ; mHealth ; user-computer interface ; consumer participation in delivery of health care
    Language English
    Publishing date 2017-08-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ISSN 2364-0502 ; 0943-4747
    ISSN (online) 2364-0502
    ISSN 0943-4747
    DOI 10.15265/IY-2017-016
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  7. Article ; Online: Autotransplantation of an ectopic impacted premolar with sinus lift and allogenic bone graft.

    Pang, N S / Choi, Y K / Kim, K D / Park, W

    International endodontic journal

    2011  Volume 44, Issue 10, Page(s) 967–975

    Abstract: Aim: This article presents a case report of autogenous tooth transplantation to a site which had insufficient bone volume using a sinus lift and allogenic bone graft.: Summary: An ectopic, fully impacted premolar tooth was autotransplanted from its ... ...

    Abstract Aim: This article presents a case report of autogenous tooth transplantation to a site which had insufficient bone volume using a sinus lift and allogenic bone graft.
    Summary: An ectopic, fully impacted premolar tooth was autotransplanted from its ectopic impaction site into its original site, where there was insufficient recipient vertical bone volume because of sinus expansion. The deciduous tooth was extracted from the recipient site, and the sinus membrane detached and elevated via the alveolar socket. Allogenic bone grafting was performed, and the impacted premolar was transplanted into the prepared site. To improve adaptation, the recipient site was prepared using a rapid prototype tooth model, a replica tooth which allowed complete socket preparation in advanced of the actual removal of the donor tooth. The donor tooth was fixed with sutures and maintained for 17 days to allow physiologic movement. Root canal treatment was initiated 24 days after autotransplantation, and an intra-canal medicament was used for 4 months. Canal filling was completed 5 months after autotransplantation. There was no root resorption of the transplanted tooth, and the grafted bone was well preserved and had no signs of infection.
    Key learning points: When the recipient bone volume is insufficient, autotransplantation can be preceded by bony augmentation. The preparation of the recipient tooth socket using a tooth replica from CBCT reduces the extra-oral time of the actual tooth and promotes better periodontal ligament healing. Careful evaluation of the pulp status of the donor tooth is important in advance of timely endodontic treatment.
    MeSH term(s) Adolescent ; Bicuspid/transplantation ; Bone Transplantation/methods ; Calcium Hydroxide/therapeutic use ; Dental Pulp Necrosis/etiology ; Dental Pulp Necrosis/therapy ; Follow-Up Studies ; Graft Survival ; Humans ; Male ; Maxilla/surgery ; Postoperative Complications ; Root Canal Irrigants/therapeutic use ; Root Canal Obturation ; Root Canal Therapy ; Sinus Floor Augmentation/methods ; Tooth Eruption, Ectopic/surgery ; Tooth Socket/surgery ; Tooth, Impacted/surgery ; Transplantation, Autologous ; Transplantation, Homologous
    Chemical Substances Root Canal Irrigants ; Calcium Hydroxide (PF5DZW74VN)
    Language English
    Publishing date 2011-10
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603734-3
    ISSN 1365-2591 ; 0143-2885
    ISSN (online) 1365-2591
    ISSN 0143-2885
    DOI 10.1111/j.1365-2591.2011.01902.x
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  8. Article ; Online: Association between prolonged breastfeeding and bone mineral density and osteoporosis in postmenopausal women: KNHANES 2010-2011.

    Hwang, I R / Choi, Y K / Lee, W K / Kim, J G / Lee, I K / Kim, S W / Park, K G

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

    2016  Volume 27, Issue 1, Page(s) 257–265

    Abstract: Unlabelled: This study showed that a negative correlation between duration of breastfeeding and bone mineral density (BMD) in the lumbar spine and prolonged breastfeeding is an independent risk for osteoporosis in postmenopausal women. The present study ...

    Abstract Unlabelled: This study showed that a negative correlation between duration of breastfeeding and bone mineral density (BMD) in the lumbar spine and prolonged breastfeeding is an independent risk for osteoporosis in postmenopausal women. The present study suggests that postmenopausal women with a history of prolonged breastfeeding require more careful screening for osteoporosis.
    Introduction: Several studies suggest that breastfeeding and childbirth lead to maternal calcium loss and a decline in BMD. While the association between breastfeeding and BMD immediately after weaning is well-established, the effects of breastfeeding on postmenopausal women have been controversial. The aim of this study was to examine the effects of breastfeeding on bone mineral density (BMD) and the prevalence of osteoporosis in postmenopausal women.
    Methods: The present study was a cross-sectional survey based on the Korea National Health and Nutrition Examination Survey (KNHANES) 2010 and 2011 data. The association between breastfeeding and BMD and osteoporosis was examined in 1222 postmenopausal women.
    Results: The duration of breastfeeding and BMD in the lumbar spine showed a negative correlation. The association between duration of breastfeeding and BMD remained significant after adjustment for reproductive factors and other confounding factors (P = 0.008). However, the number of deliveries and age at the time of delivery did not correlate with BMD at any site after adjustment. Moreover, the prevalence of osteoporosis in postmenopausal women with a history of prolonged breastfeeding was significantly higher than that in women with a short history of breastfeeding (≥37 months, OR = 3.292; 95 % CI 1.485-7.299). The prevalence of lumbar spine fracture showed a significant increasing trend with the increase in the duration of breastfeeding.
    Conclusion: Prolonged breastfeeding was significantly associated with low BMD in the lumbar spine and higher prevalence of osteoporosis. However, the number of deliveries or age at the time of childbirth did not influence BMD.
    MeSH term(s) Absorptiometry, Photon/methods ; Aged ; Bone Density/physiology ; Breast Feeding/adverse effects ; Cross-Sectional Studies ; Female ; Femur/physiopathology ; Health Surveys ; Humans ; Lactation/physiology ; Lumbar Vertebrae/physiopathology ; Middle Aged ; Osteoporosis, Postmenopausal/epidemiology ; Osteoporosis, Postmenopausal/etiology ; Osteoporosis, Postmenopausal/physiopathology ; Republic of Korea/epidemiology ; Spinal Fractures/epidemiology ; Spinal Fractures/etiology ; Spinal Fractures/physiopathology ; Time Factors
    Language English
    Publishing date 2016-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1064892-6
    ISSN 1433-2965 ; 0937-941X
    ISSN (online) 1433-2965
    ISSN 0937-941X
    DOI 10.1007/s00198-015-3292-x
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  9. Article: Evaluation of a delivery system and monitors for ventilator administration of nitric oxide.

    Choi, Y K / Yukioka, H / Yamada, T / Hayashi, M / Fujimori, M

    Journal of anesthesia

    2013  Volume 9, Issue 4, Page(s) 318–323

    Abstract: The aim of this study was to compare nitric oxide (NO) and nitrogen dioxide (NO2) measurements obtained by chemiluminescence and electrochemical monitors using a delivery system for ventilator administration of NO. The formation of NO2 in this system and ...

    Abstract The aim of this study was to compare nitric oxide (NO) and nitrogen dioxide (NO2) measurements obtained by chemiluminescence and electrochemical monitors using a delivery system for ventilator administration of NO. The formation of NO2 in this system and the efficacy of a soda-lime absorber to scavenge NO2 from inspiratory gas were also evaluated. Various concentrations of NO without and with soda lime were administered to a model lung via a Servo ventilator 900C with controlled ventilation by setting mass-flow regulators to maintain desired concentrations of NO in 80% O2. Close correlations were found between NO concentrations, as well as NO2 concentrations, measured using electrochemical monitors (TM100; 1002, PACII) and a chemiluminescence monitor (CLA-510SS). Soda-lime removed NO2 almost completely during administration of 0-25 p.p.m. NO, although a high concentration of NO2 appeared in the breathing circuit without soda lime. Four hundred grams of soda lime continued to absorb NO2 effectively during long-term administration of inhaled NO.These findings suggest that electrochemical monitoring is accurate and clinically useful for measurements of NO and NO2 concentrations, and that low doses of inhaled NO can be administered safely and reliably with the NO delivery system using a soda-lime absorber and mass-flow regulators.
    Language English
    Publishing date 2013-07-10
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1107821-2
    ISSN 1438-8359 ; 0913-8668
    ISSN (online) 1438-8359
    ISSN 0913-8668
    DOI 10.1007/BF02479944
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  10. Article: Continuous inferior mesenteric ganglion block for the control of abdominal pain.

    Choi, Y K / Novembre, E

    Regional anesthesia and pain medicine

    1999  Volume 24, Issue 4, Page(s) 358–360

    Abstract: Background and objectives: A 71-year-old woman was referred for control of intractable left-sided abdominal pain and constipation caused by stage 2B rectosigmoid colon cancer. She was treated with an intravenous morphine sulfate infusion at 4 mg/h which ...

    Abstract Background and objectives: A 71-year-old woman was referred for control of intractable left-sided abdominal pain and constipation caused by stage 2B rectosigmoid colon cancer. She was treated with an intravenous morphine sulfate infusion at 4 mg/h which made her drowsy and lethargic. Because the distal colon is innervated by the inferior mesenteric sympathetic ganglion, it was hypothesized that a continuous block of this ganglion would provide both pain control and increased intestinal motility.
    Methods: The patient was placed in a prone position, and a Tuohy needle was placed at an entry site 7 cm lateral to the L3 spinous process. The needle was advanced 2 cm anterior to the L3 vertebral body with fluoroscopic guidance. An 18-gauge indwelling catheter was placed through the needle and a continuous infusion with 0.1% bupivacaine was maintained for 4 days.
    Results: The patient obtained immediate pain relief and bowel motility. She remained awake and comfortable throughout the duration of therapy. She was discharged home 3 days after stopping the infusion and required a minimal amount of opioids.
    Conclusion: Continuous inferior mesenteric ganglion block may be an option in providing relief for pain caused by distal colon pathology.
    MeSH term(s) Abdominal Pain/drug therapy ; Abdominal Pain/etiology ; Aged ; Autonomic Nerve Block/methods ; Colonic Neoplasms/complications ; Constipation/etiology ; Constipation/therapy ; Female ; Ganglia, Autonomic ; Humans ; Mesentery/innervation
    Language English
    Publishing date 1999-07
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1016/s1098-7339(99)90112-8
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