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  1. Article ; Online: Double-Barreled Wet Colostomy After Pelvic Exenteration.

    Cholewa, Hanna / Sancho-Muriel, Jorge / Flor-Lorente, Blas

    Diseases of the colon and rectum

    2023  Volume 67, Issue 1, Page(s) e13–e14

    MeSH term(s) Humans ; Colostomy ; Pelvic Exenteration ; Urinary Diversion
    Language English
    Publishing date 2023-08-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 212581-x
    ISSN 1530-0358 ; 0012-3706
    ISSN (online) 1530-0358
    ISSN 0012-3706
    DOI 10.1097/DCR.0000000000002757
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Perianal extramammary Paget disease: our experience of two cases - a video vignette.

    Filotico, Marcello / Sancho-Muriel, Jorge / Cholewa, Hanna / Frasson, Matteo / Castro, Roberto Adriano / Flor-Lorente, Blas

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2024  

    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Letter
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16928
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Full-thickness rectal advancement flap for complex fistula-in-ano using indocyanine green fluorescence.

    Primo-Romaguera, Vicent / López, David Plazas / Álvarez-Sarrado, Eduardo / Sancho-Muriel, Jorge / Cholewa, Hanna / Millan, Monica

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2023  Volume 25, Issue 6, Page(s) 1300–1301

    MeSH term(s) Humans ; Indocyanine Green ; Fluorescence ; Rectum/surgery ; Rectal Fistula/surgery ; Surgical Flaps ; Treatment Outcome
    Chemical Substances Indocyanine Green (IX6J1063HV)
    Language English
    Publishing date 2023-02-21
    Publishing country England
    Document type Letter
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A comparison of whole-mount and conventional sections for pathological mesorectal extension and circumferential resection margin assessment after total mesorectal excision.

    Giner, Francisco / Frasson, Matteo / Cholewa, Hanna / Sancho-Muriel, Jorge / García-Gómez, Enrique / Hernández, Josselyn A / Flor-Lorente, Blas / García-Granero, Eduardo

    Cirugia espanola

    2024  

    Abstract: Introduction: The objective of the study is to compare 2 techniques for histological handling of rectal cancer specimens, namely whole-mount in a large block vs conventional sampling using small blocks, for mesorectal pathological assessment of ... ...

    Abstract Introduction: The objective of the study is to compare 2 techniques for histological handling of rectal cancer specimens, namely whole-mount in a large block vs conventional sampling using small blocks, for mesorectal pathological assessment of circumferential resection margin status and depth of tumor invasion into the mesorectal fat.
    Methods: This is a prospective study including 27 total mesorectal excision specimens of rectal cancer from patients treated for primary rectal carcinoma between 2020 and 2022 in a specialized multidisciplinary Colorectal Unit. For each total mesorectal excision specimen, 2 contiguous representative tumoral slices were selected and comparatively analyzed with whole-mount and small blocks macroscopic dissection techniques, enabling comparison between them in the same surgical specimen. The agreement between the 2 techniques to assess the distance of the tumor from the circumferential resection margin as well as the depth of tumor invasion was evaluated with the Student's t-test for paired samples, Pearson's correlation coefficient, and the Bland-Altman method comparison analysis.
    Results: Complete mesorectal excision was observed in 8% of cases. Circumferential resection margin involvement was observed in only one case (4 %). The whole-mount and small block techniques obtained similar results when we assessed the distance to the circumferential resection margin (t-test P = 0.8, r = 0.92) and the depth of mesorectal infiltration (t-test P = 0.6, r = 0.95).
    Conclusions: Both gross dissection techniques (whole-mount vs multiple small cassettes) are equivalent and reliable to assess the distance to circumferential resection margin and the depth of mesorectal infiltration in the mesorectal fat in rectal cancer staging.
    Language English
    Publishing date 2024-02-17
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.cireng.2024.01.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: "Tubeless" esophagectomy: Less is more.

    Bruna, Marcos / Mingol, Fernando / Navasquillo, Mireia / Cholewa, Hanna / Vaqué, Francisco Javier

    Cirugia espanola

    2021  Volume 99, Issue 6, Page(s) 457–462

    Abstract: The esophageal cancer surgery is a complex procedure with elevated rates of both morbidity and mortality, which is why, in order to achieve adequate results, it should be performed in high volume centers, where complete multidisciplinary support is ... ...

    Abstract The esophageal cancer surgery is a complex procedure with elevated rates of both morbidity and mortality, which is why, in order to achieve adequate results, it should be performed in high volume centers, where complete multidisciplinary support is available and recent clinical guidelines are applied. We describe the initial experience and the technique of "tubeless" esophagectomy where esophageal resection and mediastinal lymphadenectomy are performed and no drains nor tubes of any kind are placed, with the aim to decrease the level of surgical aggression, enhance the postoperative comfort and accelerate the patient́s recovery.
    MeSH term(s) Drainage ; Esophageal Neoplasms/surgery ; Esophagectomy ; Humans ; Lymph Node Excision ; Mediastinum
    Language English
    Publishing date 2021-06-01
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.cireng.2021.05.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Early colorectal cancer diagnosed after endoscopic resection: Conservative treatment is safe in most of the cases. Proposal for a risk-based management.

    Sancho-Muriel, Jorge / Pellino, Gianluca / Cholewa, Hanna / Giner, Francisco / Bustamante-Balén, Marco / Montesarchio, Luca / García-Granero, Eduardo / Frasson, Matteo

    Cirugia espanola

    2022  Volume 100, Issue 10, Page(s) 635–640

    Abstract: Introduction: Endoscopic resection offers advantages over surgical resection for early colorectal cancer (ECC). However, there might be a presumed risk of recurrence. We aimed to determine the risk of recurrence after endoscopic removal of ECC.: ... ...

    Abstract Introduction: Endoscopic resection offers advantages over surgical resection for early colorectal cancer (ECC). However, there might be a presumed risk of recurrence. We aimed to determine the risk of recurrence after endoscopic removal of ECC.
    Methods: A single-centre series of endoscopic resections for ECC. Patients were stratified according to four risk factors: positive resection margins, Haggitt 4, lymphatic/vascular invasion and tumour budding.
    Results: We included 127 patients. Haggitt classification was grade 4 in 54.0%. Positive margins were found in 43 (33.9%), 16 (12.6%) had lymphatic or vascular invasion, and 5 (4.0%) had high grade budding. In 82 (64.5%) endoscopic excision was the definitive treatment, 45 (35.4%) underwent surgery. Six patients (13.3%) had residual tumour on specimen and/or node metastases. Postoperative complications occurred in ten (22.2%). At a median follow-up of 63 months, none of the 82 patients treated with endoscopic resection alone had recurrence. After stratifying patients according to risk factors, those who had residual tumour also had ≥2 risk factors.
    Conclusions: Endoscopic follow up might be a valid option for patients with ECC. A risk-adjusted management seems prudent.
    MeSH term(s) Colorectal Neoplasms/pathology ; Colorectal Neoplasms/surgery ; Conservative Treatment ; Humans ; Margins of Excision ; Neoplasm Invasiveness ; Neoplasm, Residual ; Retrospective Studies
    Language English
    Publishing date 2022-09-15
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.cireng.2022.08.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Small bowel obstruction secondary to a pericecal hernia in an adult patient, an extremely rare condition.

    Sancho-Muriel, Jorge / Cholewa, Hanna / Abelló, David / Cepeda, Elena / Frasson, Matteo / García-Granero, Eduardo

    Cirugia y cirujanos

    2020  Volume 88, Issue Suppl 1, Page(s) 91–93

    Abstract: Internal hernias are defined by the protrusion of an abdominal organ through a peritoneal or mesenteric aperture. They are responsable for up to 5.8% of all small bowel obstructions (SBOs). Pericecal hernia is a highly unusual variation. We present a ... ...

    Title translation Obstrucción de intestino delgado en un paciente adulto secundaria a hernia pericecal, una patología extremadamente infrecuente.
    Abstract Internal hernias are defined by the protrusion of an abdominal organ through a peritoneal or mesenteric aperture. They are responsable for up to 5.8% of all small bowel obstructions (SBOs). Pericecal hernia is a highly unusual variation. We present a case of a 17-year-old Asian male turned to the emergency department due to abrupt abdominal pain and peritonitis. An emergent laparotomy revealed a small bowel herniation through the avascular space of Treves with small bowel necrosis. A pericecal hernia is an extremely unusual clinical entity; however, it should be considered in the differential diagnosis of SBO.
    MeSH term(s) Adolescent ; Adult ; Hernia/complications ; Hernia/diagnostic imaging ; Hernia, Abdominal/complications ; Hernia, Abdominal/diagnostic imaging ; Humans ; Internal Hernia ; Intestinal Obstruction/diagnostic imaging ; Intestinal Obstruction/etiology ; Intestinal Obstruction/surgery ; Intestine, Small/diagnostic imaging ; Male ; Mesentery
    Language English
    Publishing date 2020-08-13
    Publishing country Mexico
    Document type Case Reports ; Journal Article
    ZDB-ID 730699-4
    ISSN 2444-054X ; 0009-7411
    ISSN (online) 2444-054X
    ISSN 0009-7411
    DOI 10.24875/CIRU.20001629
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The percentage of mesorectal infiltration as a prognostic factor after curative surgery for pT3 rectal cancer.

    Sancho-Muriel, Jorge / Giner, Francisco / Cholewa, Hanna / Garcia-Granero, Álvaro / Roselló, Susana / Flor-Lorente, Blas / Cervantes, Andres / Garcia-Granero, Eduardo / Frasson, Matteo

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2023  Volume 25, Issue 6, Page(s) 1135–1143

    Abstract: Aim: The aim of this study is to evaluate the prognostic value of a novel variable - the percentage of mesorectal infiltration (PMI) - in pT3 rectal cancer.: Method: A cohort of 241 patients with pT3 rectal adenocarcinoma, operated on between ... ...

    Abstract Aim: The aim of this study is to evaluate the prognostic value of a novel variable - the percentage of mesorectal infiltration (PMI) - in pT3 rectal cancer.
    Method: A cohort of 241 patients with pT3 rectal adenocarcinoma, operated on between February 2002 and May 2019, was selected for the analysis. Data concerning patient, treatment and tumour characteristics were collected. The depth of mesorectal infiltration (DMI) and the distance between the deepest invasion and the circumferential resection margin (CRM) were measured. The PMI was calculated using a formula combining these parameters.
    Results: Neoadjuvant therapy was administered in 33.2% of cases. A complete mesorectal excision was achieved in 74% of patients. The CRM was affected in 24 patients (9.9%). The 5-year actuarial local recurrence (LR), overall recurrence (OR) and overall survival (OS) rates were 7.5%, 22.9% and 72.4%, respectively. The PMI was significantly associated with worse oncological outcomes regarding LR (p = 0.009), OR (p = 0.001) and OS (p = 0.016) rates. A cut-off value of PMI >60% had the highest specificity (80%) for LR (p = 0.026), OR (p = 0.04) and OS (p = 0.07).
    Conclusion: The PMI has an adverse prognostic impact on the oncological results following surgery for pT3 rectal cancer. It allows prediction of the risk of both LR and distant recurrence with higher accuracy than the DMI or the distance to the CRM. A PMI >60% may be used as a cut off value while subclassifying pT3 rectal tumours. It may influence decision-making while establishing adjuvant treatment and the follow-up schedule.
    MeSH term(s) Humans ; Prognosis ; Rectum/surgery ; Rectal Neoplasms/pathology ; Margins of Excision ; Neoplasm Recurrence, Local/pathology
    Language English
    Publishing date 2023-03-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Early colorectal cancer diagnosed after endoscopic resection: Conservative treatment is safe in most of the cases. Proposal for a risk-based management.

    Sancho-Muriel, Jorge / Pellino, Gianluca / Cholewa, Hanna / Giner, Francisco / Bustamante-Balén, Marco / Montesarchio, Luca / García-Granero, Eduardo / Frasson, Matteo

    Cirugia espanola

    2021  

    Abstract: Introduction: Endoscopic resection offers advantages over surgical resection for early colorectal cancer (ECC). However, there might be a presumed risk of recurrence. We aimed to determine the risk of recurrence after endoscopic removal of ECC.: ... ...

    Abstract Introduction: Endoscopic resection offers advantages over surgical resection for early colorectal cancer (ECC). However, there might be a presumed risk of recurrence. We aimed to determine the risk of recurrence after endoscopic removal of ECC.
    Methods: A single-centre series of endoscopic resections for ECC. Patients were stratified according to four risk factors: positive resection margins, Haggitt 4, lymphatic/vascular invasion and tumour budding.
    Results: We included 127 patients. Haggitt classification was grade 4 in 54.0%. Positive margins were found in 43 (33.9%), 16 (12.6%) had lymphatic or vascular invasion, and 5 (4.0%) had high grade budding. In 82 (64.5%) endoscopic excision was the definitive treatment, 45 (35.4%) underwent surgery. Six patients (13.3%) had residual tumour on specimen and/or node metastases. Postoperative complications occurred in ten (22.2%). At a median follow-up of 63 months, none of the 82 patients treated with endoscopic resection alone had recurrence. After stratifying patients according to risk factors, those who had residual tumour also had ≥2 risk factors.
    Conclusions: Endoscopic follow up might be a valid option for patients with ECC. A risk-adjusted management seems prudent.
    Language Spanish
    Publishing date 2021-06-10
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.ciresp.2021.04.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Extended right hemicolectomy with central ligation of the middle colic vessels - a video vignette.

    Cholewa, Hanna / Perez-Girbes, Alexandre / Avelino González, Lourdes / Flor Lorente, Blas / García-Granero, Eduardo / Sancho-Muriel, Jorge

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2021  Volume 23, Issue 8, Page(s) 2214–2215

    MeSH term(s) Colectomy ; Colic ; Colonic Neoplasms/surgery ; Humans ; Laparoscopy ; Ligation ; Lymph Node Excision ; Mesocolon/surgery
    Language English
    Publishing date 2021-06-18
    Publishing country England
    Document type Letter ; Video-Audio Media
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.15747
    Database MEDical Literature Analysis and Retrieval System OnLINE

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