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  1. Article ; Online: When Epidemiology Meets Physiology: Early Menopause and Associated Respiratory Risk.

    Chotirmall, Sanjay H

    Annals of the American Thoracic Society

    2020  Volume 17, Issue 4, Page(s) 419–420

    MeSH term(s) Bronchodilator Agents ; Female ; Menopause ; Respiratory Physiological Phenomena
    Chemical Substances Bronchodilator Agents
    Language English
    Publishing date 2020-04-01
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202002-090ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5828: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Leveraging the Omics Revolution for Nontuberculous Mycobacteria Biomarkers.

    Chotirmall, Sanjay H / Aliberti, Stefano

    Chest

    2022  Volume 161, Issue 5, Page(s) 1129–1131

    MeSH term(s) Biomarkers ; Humans ; Mycobacterium Infections, Nontuberculous/diagnosis ; Mycobacterium Infections, Nontuberculous/genetics ; Mycobacterium Infections, Nontuberculous/microbiology ; Nontuberculous Mycobacteria/genetics
    Chemical Substances Biomarkers
    Language English
    Publishing date 2022-05-05
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2021.12.646
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui III Zs.45: Show issues Location:
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  3. Article ; Online: Stratifying Bronchiectasis: Getting to within a

    Chotirmall, Sanjay H

    American journal of respiratory and critical care medicine

    2019  Volume 200, Issue 8, Page(s) 952–954

    MeSH term(s) Humans ; Pregnancy ; Bronchiectasis ; Extracellular Traps ; Infections ; Respiratory System ; Female
    Language English
    Publishing date 2019-06-20
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.201906-1275ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh II Zs.80: Show issues Location:
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  4. Article ; Online: Applying Next-Generation Sequencing and Multi-Omics in Chronic Obstructive Pulmonary Disease.

    Tiew, Pei Yee / Meldrum, Oliver W / Chotirmall, Sanjay H

    International journal of molecular sciences

    2023  Volume 24, Issue 3

    Abstract: Microbiomics have significantly advanced over the last decade, driven by the widespread availability of next-generation sequencing (NGS) and multi-omic technologies. Integration of NGS and multi-omic datasets allow for a holistic assessment of ... ...

    Abstract Microbiomics have significantly advanced over the last decade, driven by the widespread availability of next-generation sequencing (NGS) and multi-omic technologies. Integration of NGS and multi-omic datasets allow for a holistic assessment of endophenotypes across a range of chronic respiratory disease states, including chronic obstructive pulmonary disease (COPD). Valuable insight has been attained into the nature, function, and significance of microbial communities in disease onset, progression, prognosis, and response to treatment in COPD. Moving beyond single-biome assessment, there now exists a growing literature on functional assessment and host-microbe interaction and, in particular, their contribution to disease progression, severity, and outcome. Identifying specific microbes and/or metabolic signatures associated with COPD can open novel avenues for therapeutic intervention and prognosis-related biomarkers. Despite the promise and potential of these approaches, the large amount of data generated by such technologies can be challenging to analyze and interpret, and currently, there remains a lack of standardized methods to address this. This review outlines the current use and proposes future avenues for the application of NGS and multi-omic technologies in the endophenotyping, prognostication, and treatment of COPD.
    MeSH term(s) Humans ; Multiomics ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/genetics ; Pulmonary Disease, Chronic Obstructive/therapy ; Microbiota/genetics ; Host Microbial Interactions ; High-Throughput Nucleotide Sequencing
    Language English
    Publishing date 2023-02-03
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24032955
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reply to Ward

    Mac Aogáin, Micheál / Narayana, Jayanth Kumar / Chotirmall, Sanjay H

    American journal of respiratory and critical care medicine

    2023  Volume 208, Issue 5, Page(s) 631–632

    Language English
    Publishing date 2023-06-23
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202305-0872LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh II Zs.80: Show issues Location:
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  6. Article ; Online: One Small Step for Neutrophils, One Giant Leap for Bronchiectasis.

    Chotirmall, Sanjay H

    American journal of respiratory and critical care medicine

    2018  Volume 198, Issue 7, Page(s) 828–830

    MeSH term(s) Bronchiectasis ; Humans ; Neutrophils
    Language English
    Publishing date 2018-05-03
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.201804-0685ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.80: Show issues Location:
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  7. Article: Mucus, Microbiomes and Pulmonary Disease.

    Meldrum, Oliver W / Chotirmall, Sanjay H

    Biomedicines

    2021  Volume 9, Issue 6

    Abstract: The respiratory tract harbors a stable and diverse microbial population within an extracellular mucus layer. Mucus provides a formidable defense against infection and maintaining healthy mucus is essential to normal pulmonary physiology, promoting immune ...

    Abstract The respiratory tract harbors a stable and diverse microbial population within an extracellular mucus layer. Mucus provides a formidable defense against infection and maintaining healthy mucus is essential to normal pulmonary physiology, promoting immune tolerance and facilitating a healthy, commensal lung microbiome that can be altered in association with chronic respiratory disease. How one maintains a specialized (healthy) microbiome that resists significant fluctuation remains unknown, although smoking, diet, antimicrobial therapy, and infection have all been observed to influence microbial lung homeostasis. In this review, we outline the specific role of polymerizing mucin, a key functional component of the mucus layer that changes during pulmonary disease. We discuss strategies by which mucin feed and spatial orientation directly influence microbial behavior and highlight how a compromised mucus layer gives rise to inflammation and microbial dysbiosis. This emerging field of respiratory research provides fresh opportunities to examine mucus, and its function as predictors of infection risk or disease progression and severity across a range of chronic pulmonary disease states and consider new perspectives in the development of mucolytic treatments.
    Language English
    Publishing date 2021-06-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines9060675
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Pseudomonas aeruginosa

    Vidaillac, Celine / Chotirmall, Sanjay H

    Expert review of respiratory medicine

    2021  Volume 15, Issue 5, Page(s) 649–662

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Bronchi ; Bronchiectasis/drug therapy ; Chronic Disease ; Humans ; Inflammation ; Pseudomonas aeruginosa
    Language English
    Publishing date 2021-04-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2479146-5
    ISSN 1747-6356 ; 1747-6348
    ISSN (online) 1747-6356
    ISSN 1747-6348
    DOI 10.1080/17476348.2021.1906225
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6963: Show issues Location:
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  9. Article ; Online: The cost of asthma control.

    Chotirmall, Sanjay H

    Respirology (Carlton, Vic.)

    2017  Volume 22, Issue 3, Page(s) 414–415

    Language English
    Publishing date 2017-04
    Publishing country Australia
    Document type Editorial
    ZDB-ID 1435849-9
    ISSN 1440-1843 ; 1323-7799
    ISSN (online) 1440-1843
    ISSN 1323-7799
    DOI 10.1111/resp.12991
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    Zs.A 4957: Show issues Location:
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  10. Article ; Online: Clinical

    Tiew, Pei Yee / Thng, Kai Xian / Chotirmall, Sanjay H

    Journal of fungi (Basel, Switzerland)

    2022  Volume 8, Issue 5

    Abstract: Pulmonary mycoses remain a global threat, causing significant morbidity and mortality. Patients with airways disease, including COPD and bronchiectasis, are at increased risks of pulmonary mycoses and its associated complications. Frequent use of ... ...

    Abstract Pulmonary mycoses remain a global threat, causing significant morbidity and mortality. Patients with airways disease, including COPD and bronchiectasis, are at increased risks of pulmonary mycoses and its associated complications. Frequent use of antibiotics and corticosteroids coupled with impaired host defenses predispose patients to fungal colonization and airway persistence, which are associated with negative clinical consequences. Notably,
    Language English
    Publishing date 2022-05-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof8050480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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