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  1. Article: Prevalence and Pregnancy Outcome of Mullerian Anomalies in Infertile Women: A Retrospective Study.

    Joshi, Bharti / Kaushal, Aayushi / Suri, Vanita / Gainder, Shalini / Choudhary, Neelam / Jamwal, Sunita / Sharma, Shruti

    Journal of human reproductive sciences

    2021  Volume 14, Issue 4, Page(s) 431–435

    Abstract: Background: Uterine anomalies arise if there is agenesis of one or two mullerian ducts, or absence of fusion or reabsorption of the septum between these ducts. The process may be partial or total and affect one or multiple parts of the tract.: Aims: ... ...

    Abstract Background: Uterine anomalies arise if there is agenesis of one or two mullerian ducts, or absence of fusion or reabsorption of the septum between these ducts. The process may be partial or total and affect one or multiple parts of the tract.
    Aims: This study was done to assess the distribution of various types of mullerian anomalies in infertile women, their classification based on ESHRE and AFS, associated anomalies, types of diagnostic modalities used, surgical interventions done(if any), various types of infertility treatment used and their outcomes.
    Setting and design: A retrospective analysis in a tertiary level hospital.
    Materials and methods: This was a retrospective study in which the women found to have mullerian anomalies were recruited from infertility clinic from July 2019 to March 2020. They were classified according to ESHRE and AFS criteria and their records were analyzed after taking various factors like age, ovarian reserve, duration of infertility, treatment given , associated ovarian and tubal factors and pregnancy outcomes.
    Statistical analysis: Analysis was performed in Excel.
    Results: There were 30 women with mullerian anomalies. Unicornuate uterus was most common anomaly. Four women required septoplasty in view of septate uterus. Five women had associated renal anomalies in form of shrunken kidney and ectopic kidney. Most of these women were considered for controlled ovarian stimulation followed by intrauterine insemination. In our study 16.6% women had successful pregnancy outcome.
    Conclusion: Mullerian anomalies continue to attract infertility specialist as they pose challenge in making clear diagnosis and its management as obstetrics outcomes are excellent after septum resection in women with septate uterus and conservative management in women with other anomalies. Proper work up of infertility and its management varies from case to case and associated factors like endometriosis, male factor, polycystic ovarian syndrome etc.
    Language English
    Publishing date 2021-12-31
    Publishing country India
    Document type Journal Article
    ZDB-ID 2418984-4
    ISSN 1998-4766 ; 0974-1208
    ISSN (online) 1998-4766
    ISSN 0974-1208
    DOI 10.4103/jhrs.jhrs_3_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Second-Trimester Medical Abortion with Misoprostol Preceded by Two Sequential Doses of Mifepristone: An Observational Study.

    Shantikumar, Usham / Bagga, Rashmi / Kalra, Jasvinder / Jain, Vanita / Suri, Vanita / Singh, Anju / Choudhary, Neelam

    Journal of obstetrics and gynaecology of India

    2021  Volume 72, Issue Suppl 1, Page(s) 26–35

    Abstract: Introduction: Based upon the pharmacokinetics of mifepristone, we postulated that repeating a dose after its half-life period may potentiate its abortifacient effect.: Methods: We administered mifepristone (200 mg) on days one and two, and ... ...

    Abstract Introduction: Based upon the pharmacokinetics of mifepristone, we postulated that repeating a dose after its half-life period may potentiate its abortifacient effect.
    Methods: We administered mifepristone (200 mg) on days one and two, and misoprostol on day three (200 or 400 μg, vaginally, six-hourly, upto three doses in 12 h) in 100 women (intervention group). We compared their outcome with that of another 100 women who received the one-dose mifepristone regimen (mifepristone on day one and misoprostol on day three) during the months immediately preceding the study period (historical controls).
    Results: The mean age, parity and gestation (18 weeks) were similar in the two groups. On day three (before initiating misoprostol), cervix admitted one finger in significantly more women in the intervention group (36 versus 8% in historical controls;
    Conclusions: Second-trimester medical abortion using two sequential doses of mifepristone followed by misoprostol reduced the IAI and misoprostol requirement without adding any extra days to the existing regimen. Further randomized studies can assess if the 'two-dose' mifepristone regimen is more efficient than the 'one-dose' regimen.
    Language English
    Publishing date 2021-07-13
    Publishing country India
    Document type Journal Article
    ZDB-ID 410688-x
    ISSN 0971-9202 ; 0022-3190
    ISSN 0971-9202 ; 0022-3190
    DOI 10.1007/s13224-021-01521-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Spectrum of Birth Defects Amongst Live Birth, Stillbirths and Abortions.

    Sharma, Bharti / Venkataseshan, S / Suri, Vanita / Choudhary, Neelam / Kakkar, Nandita / Aggarwal, Neelam

    Indian journal of pediatrics

    2021  Volume 88, Issue 6, Page(s) 603

    MeSH term(s) Female ; Humans ; Live Birth ; Pregnancy ; Stillbirth/epidemiology
    Language English
    Publishing date 2021-03-23
    Publishing country India
    Document type Letter
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-021-03725-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Second trimester medical abortion in a primigravida with lupus nephritis and rapidly progressive renal failure: challenges and outcome.

    Bagga, Rashmi / Sharma, Bharti / Choudhary, Neelam / Singla, Rimpi / Saha, Pradip Kumar / Bharati, Joyita / Rajkumar Kopp, Chirag / Jain, Sanjay

    The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception

    2021  Volume 26, Issue 2, Page(s) 171–173

    Abstract: In the second trimester, medical abortion is preferred as it is less invasive, and the surgical method carries more risk. There is a paucity of published literature on medical abortion in women with renal failure requiring haemodialysis. We came across a ...

    Abstract In the second trimester, medical abortion is preferred as it is less invasive, and the surgical method carries more risk. There is a paucity of published literature on medical abortion in women with renal failure requiring haemodialysis. We came across a woman who presented with rapidly progressive renal failure at 18 weeks of gestation and required therapeutic abortion. We are reporting the challenges, outcomes, and precautions to be taken while performing a medical abortion in such a case.
    MeSH term(s) Abortifacient Agents, Nonsteroidal/administration & dosage ; Abortifacient Agents, Nonsteroidal/therapeutic use ; Abortifacient Agents, Steroidal/administration & dosage ; Abortifacient Agents, Steroidal/therapeutic use ; Abortion, Induced ; Female ; Humans ; Lupus Nephritis/complications ; Mifepristone/administration & dosage ; Mifepristone/therapeutic use ; Misoprostol/administration & dosage ; Misoprostol/therapeutic use ; Pregnancy ; Pregnancy Trimester, Second ; Renal Insufficiency/complications ; Treatment Outcome
    Chemical Substances Abortifacient Agents, Nonsteroidal ; Abortifacient Agents, Steroidal ; Misoprostol (0E43V0BB57) ; Mifepristone (320T6RNW1F)
    Language English
    Publishing date 2021-02-22
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1397560-2
    ISSN 1473-0782 ; 1362-5187
    ISSN (online) 1473-0782
    ISSN 1362-5187
    DOI 10.1080/13625187.2021.1879782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Role of Autopsy in Elective Termination of Pregnancy for Fetal Anomaly (ETOPFA): A Study from a Tertiary Care Hospital in India.

    Sharma, Bharti / Kakkar, Nandita / Aggarwal, Neelam / Suri, Vanita / Choudhary, Neelam / Raina, Ankit

    Fetal and pediatric pathology

    2018  Volume 37, Issue 4, Page(s) 254–262

    Abstract: Objective: To evaluate the fetal anomalies in all the patients who underwent elective termination of pregnancy for fetal anomalies (ETOPFA) before 20 weeks of gestation and to compare prenatal diagnosis with final diagnosis made after autopsy.: ... ...

    Abstract Objective: To evaluate the fetal anomalies in all the patients who underwent elective termination of pregnancy for fetal anomalies (ETOPFA) before 20 weeks of gestation and to compare prenatal diagnosis with final diagnosis made after autopsy.
    Methodology: Prospective study done in a tertiary care hospital in India over a period of two years which include 252 women who underwent ETOPFA. The prenatal diagnosis was compared with final diagnosis made after autopsy.
    Results: In 75.4% of cases autopsy findings were concordant with prenatal diagnosis where as in 21.6% of cases, additional findings were added. In 2.9 % of cases prenatal diagnosis was not confirmed by autopsy and found to be discordant.
    Conclusions: Autopsy plays an important role in completing the final diagnosis along with verification of prenatal diagnosis. To avoid discrepancy especially in cases of severe oligohydramnios, MRI or amnioinfusion could be offered for conformation of the diagnosis before offering ETOPFA.
    MeSH term(s) Autopsy ; Congenital Abnormalities/diagnosis ; Female ; Fetus/abnormalities ; Fetus/diagnostic imaging ; Humans ; India ; Pregnancy ; Prenatal Diagnosis/methods ; Prospective Studies ; Tertiary Care Centers
    Language English
    Publishing date 2018-09-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2165508-X
    ISSN 1551-3823 ; 1551-3815 ; 1522-7952
    ISSN (online) 1551-3823
    ISSN 1551-3815 ; 1522-7952
    DOI 10.1080/15513815.2018.1492655
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: A comparative study of the informal conditions of the plantation labourers of India and Sri Lanka

    Choudhary, Neelam / Tayal, Deeksha

    The Indian journal of labour economics : a quarterly journal of Indian Society of Labour Economics Vol. 53, No. 2 , p. 339-357

    2010  Volume 53, Issue 2, Page(s) 339–357

    Author's details Neelam Choudhary and Deeksha Tayal
    Keywords Agrarberufe ; Arbeitsbedingungen ; Atypische Beschäftigung ; Vergleich ; Indien ; Sri Lanka
    Language English
    Publishing place New Delhi
    Document type Article
    ZDB-ID 860762x
    ISSN 0971-7927
    Database ECONomics Information System

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  7. Article ; Online: Second trimester abortion in women with and without previous uterine scar: Eleven years experience from a developing country.

    Choudhary, Neelam / Bagga, Rashmi / Raveendran, Ainharan / Saha, Subhas Chandra / Dhaliwal, Lakhbir Kaur

    The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception

    2011  Volume 16, Issue 5, Page(s) 378–386

    Abstract: Objectives: To study the safety of second trimester abortion in women with previous uterine scar.: Methods: We screened the records of 518 women who underwent an abortion between 12 and 20 weeks' gestation at the Postgraduate Institute of Medical ... ...

    Abstract Objectives: To study the safety of second trimester abortion in women with previous uterine scar.
    Methods: We screened the records of 518 women who underwent an abortion between 12 and 20 weeks' gestation at the Postgraduate Institute of Medical Education and Research, Chandigarh, India, from January 2000 to December 2010. Methods used for abortion were: (i) vaginal misoprostol with or without pre-treatment with mifepristone, and (ii) intracervical dinoprostol gel or vaginal misoprostol ± extra-amniotic saline ± oxytocin infusion. Seventeen women, aborted by means of a hysterotomy, were excluded from further analysis.
    Results: Of the remaining 501 women, 44 had a uterine scar (Group 1) and 457 had none (Group 2). In Group 1, 40/44 (91%) and in Group 2, 452/457 (99%) women aborted successfully. The mean induction-abortion interval (IAI) was similar in the two groups (15.03 ± 10.69 hours and 12.52 ± 9.0 hours in Groups 1 and 2, respectively; p = 0.083). There were three uterine ruptures, 1/44 (2%) in group 1 and 2/457 (0.4%) in group 2 (p = 0.132, NS); all three women had received mifepristone followed by vaginal misoprostol.
    Conclusion: In women with a scarred uterus, midtrimester abortion may be successfully achieved using any of the aforementioned regimens.
    MeSH term(s) Abortifacient Agents, Nonsteroidal/administration & dosage ; Abortifacient Agents, Nonsteroidal/adverse effects ; Abortion, Induced/adverse effects ; Abortion, Induced/statistics & numerical data ; Adult ; Case-Control Studies ; Cicatrix/pathology ; Developing Countries ; Dinoprost/administration & dosage ; Dinoprost/adverse effects ; Female ; Humans ; India/epidemiology ; Mifepristone/administration & dosage ; Mifepristone/adverse effects ; Misoprostol/administration & dosage ; Misoprostol/adverse effects ; Pregnancy ; Pregnancy Trimester, Second ; Retrospective Studies ; Uterine Diseases/pathology ; Uterine Rupture/epidemiology ; Uterine Rupture/etiology
    Chemical Substances Abortifacient Agents, Nonsteroidal ; Misoprostol (0E43V0BB57) ; Mifepristone (320T6RNW1F) ; Dinoprost (B7IN85G1HY)
    Language English
    Publishing date 2011-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 1397560-2
    ISSN 1473-0782 ; 1362-5187
    ISSN (online) 1473-0782
    ISSN 1362-5187
    DOI 10.3109/13625187.2011.599453
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Genome-wide analysis of the heat stress response in Zebu (Sahiwal) cattle.

    Mehla, Kusum / Magotra, Ankit / Choudhary, Jyoti / Singh, A K / Mohanty, A K / Upadhyay, R C / Srinivasan, Surendran / Gupta, Pankaj / Choudhary, Neelam / Antony, Bristo / Khan, Farheen

    Gene

    2014  Volume 533, Issue 2, Page(s) 500–507

    Abstract: Environmental-induced hyperthermia compromises animal production with drastic economic consequences to global animal agriculture and jeopardizes animal welfare. Heat stress is a major stressor that occurs as a result of an imbalance between heat ... ...

    Abstract Environmental-induced hyperthermia compromises animal production with drastic economic consequences to global animal agriculture and jeopardizes animal welfare. Heat stress is a major stressor that occurs as a result of an imbalance between heat production within the body and its dissipation and it affects animals at cellular, molecular and ecological levels. The molecular mechanism underlying the physiology of heat stress in the cattle remains undefined. The present study sought to evaluate mRNA expression profiles in the cattle blood in response to heat stress. In this study we report the genes that were differentially expressed in response to heat stress using global scale genome expression technology (Microarray). Four Sahiwal heifers were exposed to 42°C with 90% humidity for 4h followed by normothermia. Gene expression changes include activation of heat shock transcription factor 1 (HSF1), increased expression of heat shock proteins (HSP) and decreased expression and synthesis of other proteins, immune system activation via extracellular secretion of HSP. A cDNA microarray analysis found 140 transcripts to be up-regulated and 77 down-regulated in the cattle blood after heat treatment (P<0.05). But still a comprehensive explanation for the direction of fold change and the specific genes involved in response to acute heat stress still remains to be explored. These findings may provide insights into the underlying mechanism of physiology of heat stress in cattle. Understanding the biology and mechanisms of heat stress is critical to developing approaches to ameliorate current production issues for improving animal performance and agriculture economics.
    MeSH term(s) Animals ; Body Temperature/physiology ; Cattle/genetics ; Cattle/physiology ; Chromosome Mapping ; DNA-Binding Proteins/genetics ; Heat Shock Transcription Factors ; Heat-Shock Proteins/genetics ; Heat-Shock Response/genetics ; Hot Temperature ; Humidity ; Metabolic Networks and Pathways/genetics ; Microarray Analysis ; Sequence Analysis, DNA ; Transcription Factors/genetics
    Chemical Substances DNA-Binding Proteins ; Heat Shock Transcription Factors ; Heat-Shock Proteins ; Transcription Factors
    Language English
    Publishing date 2014-01-10
    Publishing country Netherlands
    Document type Controlled Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 391792-7
    ISSN 1879-0038 ; 0378-1119
    ISSN (online) 1879-0038
    ISSN 0378-1119
    DOI 10.1016/j.gene.2013.09.051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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