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Article ; Online: Formulation, characterization of Quercus infectoria (Olivier) emulsions, and in vitro, in vivo evaluation as cosmeceutical formulation.

Choudhry, Ammara / Akhtar, Naveed

2023 Volume 22, Issue 12, Page(s) 3480–3490

Abstract: Background: Pharmacological properties of Quercus infectoria Olivier (galls) have been determined to be astringent, antidiabetic, antipyretic, anti-tremor, local anesthetic, and anti-parkinsonism. The galls of Quercus infectoria have been used for ... ...

Abstract	Background: Pharmacological properties of Quercus infectoria Olivier (galls) have been determined to be astringent, antidiabetic, antipyretic, anti-tremor, local anesthetic, and anti-parkinsonism. The galls of Quercus infectoria have been used for millennia in traditional oriental medicine in Asian nations to treat inflammatory illnesses. Aims: The study's objective was to create a Quercus infectoria Olivier gall extract in stable water in oil (w/o) emulsion and to check its effects on the mechanical properties of skin and antiaging effects. Method: The galls were macerated in absolute methanol. Quercus infectoria Olivier gall extract's antioxidant property was evaluated using the 2, 2-diphenyl-1-picrylhydrazyl (DPPH) technique. Stearic acid, cetyl alcohol, KOH, glycerin, and distilled water were used to create the emulsion. The test (with extract) and control (without extract) emulsions were made, respectively, using the same process. Stability tests (color, liquefaction, microscopy, phase separation, and pH) are performed in in vitro, lasted 72 days at four distinct storage temperatures that is 8°C, 25°C, 40°C, and 40°C + 75% RH for both the control and test formulations. By using spectrophotometry, the (SPF) sun protection factors of the two formulations were calculated at various concentrations. Extract from Quercus infectoria underwent phytochemical investigation as well. Results: The results showed that Quercus infectoria Olivier has antioxidant and (SPF) sun protection properties, reduce sebum, increases elasticity and stable emulsion containing 04% Quercus infectoria gall extract which might be used as topical antiaging formulation.
MeSH term(s)	Humans ; Plant Extracts/therapeutic use ; Antioxidants/pharmacology ; Quercus/chemistry ; Cosmeceuticals ; Emulsions ; Water
Chemical Substances	Plant Extracts ; Antioxidants ; Cosmeceuticals ; Emulsions ; Water (059QF0KO0R)
Language	English
Publishing date	2023-06-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2280551-5
ISSN	1473-2165 ; 1473-2130
ISSN (online)	1473-2165
ISSN	1473-2130
DOI	10.1111/jocd.15865
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Zs.A 6539: Show issues

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Book ; Thesis: Resorbierbare Carrier für bone morphogenetic Protein

Choudhry, Arash

histomorphologische und histomorphometrische Untersuchungen im heterotopen Lagergewebe der Ratte

2005

Author's details	vorgelegt von Arash Choudhry
Subject code	617.69
Language	German
Size	109 Bl., Ill., graph. Darst., 30 cm
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Heidelberg, Univ., Diss., 22005
HBZ-ID	HT014851856
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Article: Posterior Interosseous Neuropathy Related to a Loose Distal Biceps Cortical Button: A Case Series.

Amer, Kamil M / Bridges, Tiffany N / Choudhry, Arsalaan / Jones, Christopher M

The archives of bone and joint surgery

2024 Volume 12, Issue 2, Page(s) 139–143

Abstract: Posterior interosseous nerve (PIN) injury is an uncommon yet debilitating complication following distal bicep tendon repair. There are case reports of acute intraoperative PIN injury related to retractor placement, drill trajectory, and nerve ... ...

Abstract	Posterior interosseous nerve (PIN) injury is an uncommon yet debilitating complication following distal bicep tendon repair. There are case reports of acute intraoperative PIN injury related to retractor placement, drill trajectory, and nerve incarceration. We report three cases of delayed PIN neuropathy in the setting of a loose cortical button. All patients had resolution of their pain with removal of the cortical button and decompression of the radial tunnel. The purpose of this case series is to: 1) highlight the possibility of a loose cortical bicep button as the cause of proximal forearm pain and PIN neuropathy in the early or late postoperative timeframe; and 2) emphasize the importance of proper surgical technique and use of intraoperative fluoroscopy to assure the cortical button is well-fixed and flush with the radial shaft. .
Language	English
Publishing date	2024-02-21
Publishing country	Iran
Document type	Case Reports
ZDB-ID	2782053-1
ISSN	2345-461X ; 2345-4644
ISSN (online)	2345-461X
ISSN	2345-4644
DOI	10.22038/ABJS.2023.75292.3483
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Article ; Online: Robotic Renal Vein Bypass: A Novel Technique for Treating a Challenging Case of Nutcracker Syndrome.

Choudhry, Asad / DeNoble, Daniel / Bratslavsky, Gennady / Feghali, Anthony

Vascular and endovascular surgery

2024 , Page(s) 15385744241249291

Abstract: This case report highlights the successful application of a robotic-assisted surgical approach in managing Nutcracker syndrome. The patient, a 36-year-old female presented with severe symptoms and underwent robotic left renal vein transposition after ... ...

Abstract	This case report highlights the successful application of a robotic-assisted surgical approach in managing Nutcracker syndrome. The patient, a 36-year-old female presented with severe symptoms and underwent robotic left renal vein transposition after failing conservative management. The procedure was performed through a minimally invasive approach utilizing the Da Vinci robotic system™ which offers enhanced visualization and precision. However, challenges arose during the renal vein anastomosis due to tension and poor flow through the transposition, requiring two revisions with a bovine pericardial patch. Ultimately, an 8 mm ringed PTFE bypass was anastomosed from the distal left renal vein to the Inferior Vena Cava. Despite these challenges, the patient experienced a successful outcome with complete symptom resolution of this complicated pathology.
Language	English
Publishing date	2024-04-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	2076272-0
ISSN	1938-9116 ; 1538-5744
ISSN (online)	1938-9116
ISSN	1538-5744
DOI	10.1177/15385744241249291
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Article: Giant isolated profunda femoris artery aneurysm treated with aneurysmal ligation without profunda femoris artery revascularization.

Rahman, Naveed A / Williams, Zachary E / Choudhry, Asad / Surowiec, Scott

Journal of vascular surgery cases and innovative techniques

2023 Volume 9, Issue 4, Page(s) 101328

Abstract: Isolated nonruptured profunda femoris artery (PFA) aneurysms are exceedingly rare. We present the case of an 80-year-old man who initially presented with a large pulsatile mass in the right groin. Computed tomography angiography identified a giant 6-cm ... ...

Abstract	Isolated nonruptured profunda femoris artery (PFA) aneurysms are exceedingly rare. We present the case of an 80-year-old man who initially presented with a large pulsatile mass in the right groin. Computed tomography angiography identified a giant 6-cm PFA aneurysm. This was a truly isolated PFA aneurysm without any evidence of concomitant abdominal aortic or popliteal aneurysms. Potential surgical options included reconstruction with an interposition graft, endovascular coil embolization, and aneurysmal ligation. We elected to perform aneurysmal ligation of the PFA aneurysm without revascularization given the aneurysm's massive size and patency of the superficial femoral artery.
Language	English
Publishing date	2023-09-21
Publishing country	United States
Document type	Case Reports
ISSN	2468-4287
ISSN	2468-4287
DOI	10.1016/j.jvscit.2023.101328
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Article: Successful Eradication of Hepatitis-C Virus with Sofosbuvir based Antiviral treatment results in improvement in quality of life in cirrhotic patients.

Ali, Bushra / Raja, Ikram Ul Haq / Choudhry, Asad / Nawaz, Arif Amir

Pakistan journal of medical sciences

2022 Volume 38, Issue 4Part-II, Page(s) 822–825

Abstract: Objectives: To document improvement in quality of life in patients with Hepatitis-C related cirrhosis after successful eradication of the virus.: Methods: In this observational cohort study conducted at Fatima Memorial Hospital from September 2015 to ...

Abstract	Objectives: To document improvement in quality of life in patients with Hepatitis-C related cirrhosis after successful eradication of the virus. Methods: In this observational cohort study conducted at Fatima Memorial Hospital from September 2015 to July 2017, patients with HCV were assessed for improvement in quality of life by using FACIT-F questionnaire. We compared the Quality of life (QOL) score before the start of treatment with DAAs and after achieving SVR12 in various aspects of quality of life including physical, emotional, functional and social well-being. Results: A total of 71 patients, 52 (73%) were CTP class A, 18 (25%) in B and one (1.4%) in C. The mean score of QOL before AVT was 23.93±7.04 and after achieving SVR it was 36.83±6.36 (P-value <0.001). In the subcategories, score of functional wellbeing, physical well-being and social wellbeing were significantly improved except emotional wellbeing scores. All scores improved across the spectrum of patients in the CTP class A and B. There was only one patient in the CTP-C class. Conclusion: Chronic HCV infection complicated by cirrhosis causes a significant decline in quality of life. There was a marked improvement in the functional, social and physical health of the patients after eradication of Hepatitis-C with anti-viral therapy except emotional health of the individuals.
Language	English
Publishing date	2022-05-18
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	2032827-8
ISSN	1681-715X ; 1682-024X ; 1017-4699
ISSN (online)	1681-715X
ISSN	1682-024X ; 1017-4699
DOI	10.12669/pjms.38.4.4537
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Zs.A 3948: Show issues

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Article: One-Bone Forearm Procedure for Severe Recalcitrant Forearm Deformities in Masada IIb Hereditary Multiple Exostoses.

Agashe, Mandar Vikas / Shah, Mudit / Choudhry, Ashima / Shah, Avi / Agarwal, Saurabh / Vaidya, Sandeep

Indian journal of orthopaedics

2023 Volume 57, Issue 11, Page(s) 1777–1784

Abstract: Introduction: Hereditary multiple exostoses (HME) Masada IIB has traditionally been treated by gradual ulnar lengthening with questionable efficacy in reducing the dislocated head. One-bone forearm (OBF) has been used as a reconstructive procedure in ... ...

Abstract	Introduction: Hereditary multiple exostoses (HME) Masada IIB has traditionally been treated by gradual ulnar lengthening with questionable efficacy in reducing the dislocated head. One-bone forearm (OBF) has been used as a reconstructive procedure in forearm deformities with very scarce literature for HME. The study aims to report short-term results of OBF as a definitive procedure for severe forearm deformities in Masada IIB patients with respect to clinical and radiological parameters. Materials and methods: Four patients with HME Masada IIb were included in this retrospective study. All patients complained of forearm and wrist deformity with an abnormal bony protrusion restricting elbow motion. Indications for OBF were ulnar shortening > 3 cm, dysplastic proximal radius with convex radial head and restricted prono-supination. All patients were examined pre-operatively and post-operatively clinically and radiographically using the Peterson's outcome score. Results: The average age was 13 years (12-14 years). Pre-operative ulnar shortening, carpal slip percentage, and radial articular angle was 3.4 cm, 79.5%, and 47.5°, respectively. All radial heads were dislocated with convex articular surface restricting elbow extension and forearm prono-supination. At the latest follow-up, the mean elbow flexion was 110° with forearm in 10° supination. The mean carpal slip percentage, radial articular angle, and Peterson functional grade was 15%, 22.5°, and 8 points, respectively. The mean follow-up period was 30.25 months with no recurrence. Conclusion: We recommend one bone forearm as a definitive procedure in HME Masada IIB patients with severe forearm deformities with ulnar shortening > 3 cm and dysplastic proximal radius with a dislocated radial head, for faster return to function.
Language	English
Publishing date	2023-08-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	603194-8
ISSN	0019-5413
ISSN	0019-5413
DOI	10.1007/s43465-023-00968-6
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Article ; Online: Real-world healthcare resource utilization and costs in patients with chronic lymphocytic leukemia: differences between patients treated with first-line ibrutinib or bendamustine + rituximab.

Irwin, Debra / Wilson, Kathleen / Thompson, Stephen / Choudhry, Azhar

Current medical research and opinion

2021 Volume 37, Issue 4, Page(s) 623–628

Abstract: Background: This study evaluated the real-world healthcare resource utilization and costs in chronic lymphocytic lymphoma (CLL) patients treated with first-line ibrutinib monotherapy (IbM) therapy or bendamustine plus rituximab (BR) combination therapy.! ...

Abstract	Background: This study evaluated the real-world healthcare resource utilization and costs in chronic lymphocytic lymphoma (CLL) patients treated with first-line ibrutinib monotherapy (IbM) therapy or bendamustine plus rituximab (BR) combination therapy. Methods: Treatment-naïve CLL patients in the IBM MarketScan Research Databases were identified based on the first prescription of either IbM or BR therapy between 1 February 2014 and 30 August 2017. Results: A total of 1866 patients with 12 months of continuous enrollment (IbM Conclusion: The results of this study suggest that further research on the real-world effectiveness of IbM in comparison to BR combination therapy, given the comparatively higher rates of inpatient admissions, longer lengths of stay, and more ER visits observed in IbM patients relative to the BR patients is needed. Given the differences in costs, it is important to further examine the impact these healthcare expenditures have on the cost-effectiveness of IbM first line treatment.
MeSH term(s)	Adenine/analogs & derivatives ; Bendamustine Hydrochloride ; Health Care Costs ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy ; Patient Acceptance of Health Care ; Piperidines ; Retrospective Studies ; Rituximab
Chemical Substances	Piperidines ; ibrutinib (1X70OSD4VX) ; Rituximab (4F4X42SYQ6) ; Bendamustine Hydrochloride (981Y8SX18M) ; Adenine (JAC85A2161)
Language	English
Publishing date	2021-02-18
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80296-7
ISSN	1473-4877 ; 0300-7995
ISSN (online)	1473-4877
ISSN	0300-7995
DOI	10.1080/03007995.2021.1884540
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Article ; Online: Endovascular Coil Embolization of an Enlarging Gastroduodenal Artery Aneurysm.

Rahman, Naveed A / Lieb, Kayla R / Choudhry, Asad / Chihade, Deena B / Feghali, Anthony

Vascular and endovascular surgery

2023 Volume 58, Issue 4, Page(s) 410–413

Abstract: Gastroduodenal artery aneurysms are a rare type of visceral aneurysm that can lead to rupture and death. We present a 75-year-old male with history of hypertension, diabetes, and hyperlipidemia with an incidental finding of a 3.2 × 3.7 cm gastroduodenal ... ...

Abstract	Gastroduodenal artery aneurysms are a rare type of visceral aneurysm that can lead to rupture and death. We present a 75-year-old male with history of hypertension, diabetes, and hyperlipidemia with an incidental finding of a 3.2 × 3.7 cm gastroduodenal aneurysm found on abdominal computed tomography angiography (CTA). After refusing surgical intervention, he was seen two years later and presented with an enlarged gastroduodenal aneurysm, now 5.0 × 5.1 cm, visible on a repeat abdominal CTA. Upon his continued refusal for an open surgery, we elected for endovascular repair of this GDA aneurysm via coil embolization.
MeSH term(s)	Male ; Humans ; Aged ; Treatment Outcome ; Aneurysm/diagnostic imaging ; Aneurysm/therapy ; Blood Vessel Prosthesis ; Blood Vessel Prosthesis Implantation ; Arteries/surgery ; Embolization, Therapeutic/methods
Language	English
Publishing date	2023-11-15
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2076272-0
ISSN	1938-9116 ; 1538-5744
ISSN (online)	1938-9116
ISSN	1538-5744
DOI	10.1177/15385744231215551
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Zs.A 622: Show issues

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Article ; Online: Budgetary Impact of Bendamustine Ready-to-Dilute Products in Chronic Lymphocytic Leukemia and Non-Hodgkin Lymphoma to a United States Infusion Facility

James E / Trautman H / Thompson S / Ribalov R / Choudhry A

ClinicoEconomics and Outcomes Research, Vol Volume 13, Pp 201-

2021 Volume 211

Abstract: Elizabeth James,1 Holly Trautman,1 Stephen Thompson,2 Rinat Ribalov,3 Azhar Choudhry4 1Aventine Consulting LLC, Marblehead, MA, USA; 2Global Health Economics and Outcomes Research, Teva Branded Pharmaceutical Products R&D, Inc, Parsippany, NJ, USA; ... ...

Abstract	Elizabeth James,1 Holly Trautman,1 Stephen Thompson,2 Rinat Ribalov,3 Azhar Choudhry4 1Aventine Consulting LLC, Marblehead, MA, USA; 2Global Health Economics and Outcomes Research, Teva Branded Pharmaceutical Products R&D, Inc, Parsippany, NJ, USA; 3Global Health Economics and Outcomes Research, Teva Pharmaceutical Industries Ltd, Petah Tikva, Israel; 4Medical Affairs, Teva Branded Pharmaceutical Products R&D, Inc, Parsippany, NJ, USACorrespondence: Elizabeth James Tel +1 425 290 2148Email elizabeth@aventine-consulting.comBackground: Bendamustine hydrochloride (BND HCl) is indicated for first-line treatment of chronic lymphocytic leukemia (CLL) and rituximab-refractory indolent non-Hodgkin lymphoma (iNHL). There are two ready-to-dilute (RTD) formulations of BND HCl on the US market: a large-volume, long-duration infusion (BND-L) and a small-volume, short-duration infusion (BND-S). It is estimated that the shorter duration infusion could result in cost savings to infusion facilities.Objective: Estimate the one-year budget impact between BND-S and BND-L for use in the treatment of CLL and iNHL when all current BND-L utilization is replaced with BND-S, from the US infusion facility perspective.Methods: An illustrative budget impact model estimated the change in costs associated with a projected increase from 50% to 100% market share for BND-S. The model included CLL and iNHL patient populations. Budgetary costs reflected facility expenditures on drug acquisition and administration based on recommended dosing for BND-S and BND-L. The base-case model assumptions and inputs were derived from scientific literature and publicly available resources. The total budget impact was calculated annually, along with the differences in per patient cost; one-way sensitivity analyses were conducted.Results: Per-patient savings with BND-S use after the utilization shift were estimated at $2812.24 for CLL and $4769.01 for iNHL. Across both indications, the total annual incremental savings after the utilization shift were ...
Keywords	chronic lymphocytic leukemia ; indolent non-hodgkin lymphoma ; budget impact ; bendamustine ; infusion ; Medicine (General) ; R5-920 ; Therapeutics. Pharmacology ; RM1-950
Subject code	306
Language	English
Publishing date	2021-03-01T00:00:00Z
Publisher	Dove Medical Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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