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  1. Article: Pressures generated during nose blowing in patients with nasal complaints and normal test subjects.

    Clement, Peter / Chovanova, Hana

    Rhinology

    2003  Volume 41, Issue 3, Page(s) 152–158

    Abstract: The authors compared nasal resistance and pressures generated during breathing and nose blowing in patients with chronic sinusitis, septal deviations and a control group consisting of normal test subjects. The chronic sinusitis group generated pressures ... ...

    Abstract The authors compared nasal resistance and pressures generated during breathing and nose blowing in patients with chronic sinusitis, septal deviations and a control group consisting of normal test subjects. The chronic sinusitis group generated pressures during nose blowing that were significantly higher (898 daPa for the left side and 913 daPa for the right side) than in the other two groups. The decongestion didn't change the generated pressures very much. Pressures generated during nose blowing with both nostrils closed are much higher than pressures generated during nose blowing with one nostril open. These very high pressures could have an important role in the pathophysiology of chronic sinusitis.
    MeSH term(s) Adult ; Aged ; Airway Resistance/physiology ; Chronic Disease ; Female ; Humans ; Male ; Middle Aged ; Nasal Obstruction/physiopathology ; Nasal Septum ; Nose Deformities, Acquired/physiopathology ; Pressure/adverse effects ; Rhinomanometry/methods ; Sinusitis/physiopathology
    Language English
    Publishing date 2003-09
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article
    ZDB-ID 80336-4
    ISSN 0300-0729
    ISSN 0300-0729
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1080: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  2. Article ; Online: Human Biomonitoring Data Enables Evidence-Informed Policy to Reduce Internal Exposure to Persistent Organic Compounds: A Case Study.

    Colles, Ann / Coertjens, Dries / Morrens, Bert / Den Hond, Elly / Paulussen, Melissa / Bruckers, Liesbeth / Govarts, Eva / Covaci, Adrian / Koppen, Gudrun / Croes, Kim / Nelen, Vera / Van Larebeke, Nicolas / De Henauw, Stefaan / Fierens, Tine / Van Gestel, Griet / Chovanova, Hana / Mampaey, Maja / Van Campenhout, Karen / Loots, Ilse /
    Baeyens, Willy / Schoeters, Greet

    International journal of environmental research and public health

    2021  Volume 18, Issue 11

    Abstract: Human biomonitoring (HBM) monitors levels of environmental pollutants in human samples, which often is a topic of concern for residents near industrially contaminated sites (ICSs). Around an ICS area in Menen (Belgium), including a (former) municipal ... ...

    Abstract Human biomonitoring (HBM) monitors levels of environmental pollutants in human samples, which often is a topic of concern for residents near industrially contaminated sites (ICSs). Around an ICS area in Menen (Belgium), including a (former) municipal waste incinerator and a metal recovery plant, increasing environmental concentrations of dioxins and polychlorinated biphenyls (PCBs) were observed, causing growing concern among residents and authorities. The local community succeeded in convincing the responsible authorities to investigate the problem and offer research funding. Persistent organic pollutants (POPs) were measured in two consecutive HBM studies (2002-2006 and 2010-2011), in the context of the Flemish Environment and Health Study (FLEHS), as well as in soil and locally produced food. Meanwhile, local authorities discouraged consumption of locally produced food in a delineated area of higher exposure risk. Ultimately, HBM and environmental data enabled tailored dietary recommendations. This article demonstrates the usefulness of HBM in documenting the body burdens of residents near the ICS, identifying exposure routes, evaluating remediating actions and providing information for tailored policy strategies aiding to further exposure reduction. It also highlights the role of the local stakeholders as an example of community-based participatory research and how such an approach can create societal support for research and policy.
    MeSH term(s) Belgium ; Biological Monitoring ; Dioxins ; Environmental Monitoring ; Environmental Pollutants/analysis ; Humans ; Policy ; Polychlorinated Biphenyls/analysis
    Chemical Substances Dioxins ; Environmental Pollutants ; Polychlorinated Biphenyls (DFC2HB4I0K)
    Language English
    Publishing date 2021-05-22
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph18115559
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  3. Article ; Online: Key aspects of a Flemish system to safeguard public health interests in case of chemical release incidents.

    Smolders, Roel / Colles, Ann / Cornelis, Christa / Van Holderbeke, Mirja / Chovanova, Hana / Wildemeersch, Dirk / Mampaey, Maja / Van Campenhout, Karen

    Toxicology letters

    2014  Volume 231, Issue 3, Page(s) 315–323

    Abstract: Although well-established protocols are available for emergency services and first-responders in case of chemical release incidents, a well-developed system to monitor and safeguard public health was, until recently, lacking in Flanders. We therefore ... ...

    Abstract Although well-established protocols are available for emergency services and first-responders in case of chemical release incidents, a well-developed system to monitor and safeguard public health was, until recently, lacking in Flanders. We therefore developed a decision support system (DSS) to aid public health officials in identifying the appropriate actions in case of incidents. Although the DSS includes human biomonitoring as one of its key instruments, it also goes well beyond this instrument alone. Also other, complementary, approaches that focus more on effect assessment using in vitro toxicity testing, indirect exposures through the food chain, and parallel means of data collection (e.g. through ecosurveillance or public consultation), are integrated in the Flemish approach. Even though the DSS is set up to provide a flexible and structured decision tree, the value of expert opinion is deemed essential to account for the many uncertainties associated with the early phases of technological incidents. When the DSS and the associated instruments will be fully operational, it will provide a valuable addition to the already available protocols, and will specifically safeguard public health interests.
    MeSH term(s) Belgium ; Chemical Hazard Release ; Decision Support Techniques ; Disaster Planning/methods ; Disaster Planning/standards ; Environmental Monitoring/methods ; Hazardous Substances/toxicity ; Humans ; Public Health/methods ; Public Health/standards ; Risk Assessment/methods ; Risk Assessment/standards
    Chemical Substances Hazardous Substances
    Language English
    Publishing date 2014-12-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 433788-8
    ISSN 1879-3169 ; 0378-4274
    ISSN (online) 1879-3169
    ISSN 0378-4274
    DOI 10.1016/j.toxlet.2014.05.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1367: Show issues Location:
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  4. Article ; Online: The added value of a surveillance human biomonitoring program: The case of FLEHS in Flanders (Belgium).

    Reynders, Hans / Colles, Ann / Morrens, Bert / Mampaey, Maja / Coertjens, Dries / Koppen, Gudrun / Schoeters, Greet / Loots, Ilse / Chovanova, Hana / Winderickx, Wim / Van Campenhout, Karen

    International journal of hygiene and environmental health

    2017  Volume 220, Issue 2 Pt A, Page(s) 46–54

    Abstract: Since 2002, the Flemish Government decided to carry out the Flemish Environment and Health Survey (FLEHS), an extended human biomonitoring (HBM) program, which is integrated in the environmental health policy. Through the FLEHS studies, a vast amount of ... ...

    Abstract Since 2002, the Flemish Government decided to carry out the Flemish Environment and Health Survey (FLEHS), an extended human biomonitoring (HBM) program, which is integrated in the environmental health policy. Through the FLEHS studies, a vast amount of data such as biomarkers of exposure and effect, exposure-effect associations, time trends and geographical differences, became available to the Flemish policy makers. In order to facilitate the policy interpretation, a phased action-plan was developed collaboratively by FLEHS researchers and policy makers. In this article we look back on more than 15 years of investments of the Flemish government in HBM and reflect on how this large scaled and challenging HBM-initiative contributed to shaping the environmental health policy in Flanders. We used the FLEHS I (2002-2006) and II (2007-2011) results on persistent organic pollutants (POPs) and the resulting policy actions as an example to illustrate the added value of HBM for policy making. Policy measures for POPs, including source-related regulation (e.g. further optimization and tightening of existing Flemish legislation on open fires), investment in monitoring networks and communication and awareness campaigns, are presented and the added value for environmental health policy is discussed. We also reflect on how HBM can support science and innovation in the environmental monitoring context. Finally, we describe what society can gain from HBM in terms of opportunities for (1) feeding the political and societal debate, (2) stimulating community involvement and (3) empowering participants and citizens. All together, the gained insights and phased action plan showed that next to compliance with high scientific standards, results of the Flemish human biomonitoring campaign could be translated in targeted policy actions even for chemicals that have since long been regulated.
    MeSH term(s) Adolescent ; Adult ; Aged ; Belgium ; Environmental Monitoring ; Environmental Policy ; Environmental Pollutants/analysis ; Environmental Pollutants/blood ; Health Policy ; Humans ; Infant, Newborn ; Middle Aged ; Young Adult
    Chemical Substances Environmental Pollutants
    Language English
    Publishing date 2017-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2009176-X
    ISSN 1618-131X ; 1438-4639
    ISSN (online) 1618-131X
    ISSN 1438-4639
    DOI 10.1016/j.ijheh.2016.09.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5334: Show issues Location:
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  5. Article ; Online: Opening the research agenda for selection of hot spots for human biomonitoring research in Belgium

    Chovanova Hana / Van Campenhout Karen / Springael Johan / Loots Ilse / Koppen Gudrun / Colles Ann / Croes Kim / Morrens Bert / Keune Hans / Schoeters Greet / Nelen Vera / Baeyens Willy / Van Larebeke Nik

    Environmental Health, Vol 9, Iss 1, p

    a participatory research project

    2010  Volume 33

    Abstract: Abstract Background In order to select priority hotspots for environment and health research in Flanders (Belgium), an open procedure was organized. Environment and health hotspots are strong polluting point sources with possible health effects for ... ...

    Abstract Abstract Background In order to select priority hotspots for environment and health research in Flanders (Belgium), an open procedure was organized. Environment and health hotspots are strong polluting point sources with possible health effects for residents living in the vicinity of the hot spot. The selection procedure was part of the work of the Flemish Centre of Expertise for Environment and Health, which investigates the relation between environmental pollution and human health. The project is funded and steered by the Flemish government. Methods The involvement of other actors than merely experts is inspired by the 'analytical-deliberative' approach of the National Research Council in the United States and the extended peer community approach. These approaches stress the importance of involving different expert- and social perspectives in order to increase the knowledge base on complex issues. In the procedure used in the project a combination of expert and stakeholder input was essential. The final decision was supported by a multi-criteria analysis of expert assessment and stakeholder advice. Results The endeavour was challenging from the start because of the complicated ambition of including a diversity of actors, potential hotspots, concerns and assessment criteria, but nevertheless the procedure proved its value in both structuring and informing the decision-making process. Moreover the process gained the support of most actors participating in the process, even though the final selection could not satisfy all preferences. Conclusions Opening the research agenda exemplifies the value of inter- and transdisciplinary cooperation as well as the need for a well-structured and negotiated procedure that combines relevant factors and actors with pragmatism. The value of such a process also needs to prove itself in practice after the procedure has been completed: the tension between an ambition of openness on the one hand and a more closed attitude amongst experts on the other will continue to play a role even after closure.
    Keywords Industrial medicine. Industrial hygiene ; RC963-969 ; Public aspects of medicine ; RA1-1270
    Subject code 650
    Language English
    Publishing date 2010-07-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Opening the research agenda for selection of hot spots for human biomonitoring research in Belgium: a participatory research project.

    Keune, Hans / Morrens, Bert / Croes, Kim / Colles, Ann / Koppen, Gudrun / Springael, Johan / Loots, Ilse / Van Campenhout, Karen / Chovanova, Hana / Schoeters, Greet / Nelen, Vera / Baeyens, Willy / Van Larebeke, Nik

    Environmental health : a global access science source

    2010  Volume 9, Page(s) 33

    Abstract: Background: In order to select priority hotspots for environment and health research in Flanders (Belgium), an open procedure was organized. Environment and health hotspots are strong polluting point sources with possible health effects for residents ... ...

    Abstract Background: In order to select priority hotspots for environment and health research in Flanders (Belgium), an open procedure was organized. Environment and health hotspots are strong polluting point sources with possible health effects for residents living in the vicinity of the hot spot. The selection procedure was part of the work of the Flemish Centre of Expertise for Environment and Health, which investigates the relation between environmental pollution and human health. The project is funded and steered by the Flemish government.
    Methods: The involvement of other actors than merely experts is inspired by the 'analytical-deliberative' approach of the National Research Council in the United States and the extended peer community approach. These approaches stress the importance of involving different expert- and social perspectives in order to increase the knowledge base on complex issues. In the procedure used in the project a combination of expert and stakeholder input was essential. The final decision was supported by a multi-criteria analysis of expert assessment and stakeholder advice.
    Results: The endeavour was challenging from the start because of the complicated ambition of including a diversity of actors, potential hotspots, concerns and assessment criteria, but nevertheless the procedure proved its value in both structuring and informing the decision-making process. Moreover the process gained the support of most actors participating in the process, even though the final selection could not satisfy all preferences.
    Conclusions: Opening the research agenda exemplifies the value of inter- and transdisciplinary cooperation as well as the need for a well-structured and negotiated procedure that combines relevant factors and actors with pragmatism. The value of such a process also needs to prove itself in practice after the procedure has been completed: the tension between an ambition of openness on the one hand and a more closed attitude amongst experts on the other will continue to play a role even after closure.
    MeSH term(s) Belgium ; Community-Based Participatory Research/methods ; Environmental Exposure/analysis ; Environmental Health/methods ; Environmental Pollution/analysis ; Humans ; Research Design ; Surveys and Questionnaires
    Language English
    Publishing date 2010-07-06
    Publishing country England
    Document type Journal Article
    ISSN 1476-069X
    ISSN (online) 1476-069X
    DOI 10.1186/1476-069X-9-33
    Database MEDical Literature Analysis and Retrieval System OnLINE

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