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  1. Article ; Online: One Step Forward with Dry Surface Biofilm (DSB) of

    Rahman, Md Arifur / Amirkhani, Ardeshir / Parvin, Farhana / Chowdhury, Durdana / Molloy, Mark P / Deva, Anand Kumar / Vickery, Karen / Hu, Honghua

    International journal of molecular sciences

    2022  Volume 23, Issue 20

    Abstract: The Gram-positive ... ...

    Abstract The Gram-positive bacterium
    MeSH term(s) Humans ; Staphylococcus aureus ; Proteomics ; Argininosuccinate Synthase ; DNA Breaks, Double-Stranded ; Peptidoglycan ; Biofilms ; Staphylococcal Infections ; Glucosamine ; Transferases ; ATP-Binding Cassette Transporters ; Glucose Transport Proteins, Facilitative ; Transaminases ; Alanine ; Uridine Diphosphate
    Chemical Substances Argininosuccinate Synthase (EC 6.3.4.5) ; Peptidoglycan ; Glucosamine (N08U5BOQ1K) ; Transferases (EC 2.-) ; ATP-Binding Cassette Transporters ; Glucose Transport Proteins, Facilitative ; Transaminases (EC 2.6.1.-) ; Alanine (OF5P57N2ZX) ; Uridine Diphosphate (58-98-0)
    Language English
    Publishing date 2022-10-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms232012238
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Proteome of

    Rahman, Md Arifur / Amirkhani, Ardeshir / Chowdhury, Durdana / Mempin, Maria / Molloy, Mark P / Deva, Anand Kumar / Vickery, Karen / Hu, Honghua

    International journal of molecular sciences

    2022  Volume 23, Issue 12

    Abstract: Staphylococcus ... ...

    Abstract Staphylococcus aureus
    MeSH term(s) Biofilms ; Humans ; Proteome/metabolism ; Staphylococcal Infections/drug therapy ; Staphylococcus aureus/metabolism ; Sugars/metabolism
    Chemical Substances Proteome ; Sugars
    Language English
    Publishing date 2022-06-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23126415
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The A, B and C's of Silicone Breast Implants: Anaplastic Large Cell Lymphoma, Biofilm and Capsular Contracture.

    Mempin, Maria / Hu, Honghua / Chowdhury, Durdana / Deva, Anand / Vickery, Karen

    Materials (Basel, Switzerland)

    2018  Volume 11, Issue 12

    Abstract: Breast implantation either for cosmetic or reconstructive e purposes is one of the most common procedures performed in plastic surgery. Biofilm infection is hypothesised to be involved in the development of both capsular contracture and anaplastic large ... ...

    Abstract Breast implantation either for cosmetic or reconstructive e purposes is one of the most common procedures performed in plastic surgery. Biofilm infection is hypothesised to be involved in the development of both capsular contracture and anaplastic large cell lymphoma (ALCL). Capsular contracture is one of the principal reasons for breast revision surgery and is characterised by the tightening and hardening of the capsule surrounding the implant, and ALCL is an indolent lymphoma found only in women with textured implants. We describe the types of breast implants available with regard to their surface characteristics of surface area and roughness and how this might contribute to capsular contracture and/or biofilm formation. The pathogenesis of capsular contracture is thought to be due to biofilm formation on the implant, which results in on-going inflammation. We describe the current research into breast implant associated ALCL and how implant properties may affect its pathogenesis, with ALCL only occurring in women with textured implants.
    Language English
    Publishing date 2018-11-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma11122393
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Functional Influence of Breast Implant Outer Shell Morphology on Bacterial Attachment and Growth.

    Jones, Phoebe / Mempin, Maria / Hu, Honghua / Chowdhury, Durdana / Foley, Matthew / Cooter, Rodney / Adams, William P / Vickery, Karen / Deva, Anand K

    Plastic and reconstructive surgery

    2018  Volume 142, Issue 4, Page(s) 837–849

    Abstract: Background: The introduction of texture to the outer shell of breast implants was aimed at increasing tissue incorporation and reducing capsular contracture. It has also been shown that textured surfaces promote a higher growth of bacteria and are ... ...

    Abstract Background: The introduction of texture to the outer shell of breast implants was aimed at increasing tissue incorporation and reducing capsular contracture. It has also been shown that textured surfaces promote a higher growth of bacteria and are linked to the development of breast implant-associated anaplastic large cell lymphoma.
    Methods: The authors aimed to measure the surface area and surface roughness of 11 available implants. In addition, the authors aimed to subject these implant shells to an in vitro bacterial attachment assay with four bacterial pathogens (Staphylococcus epidermidis, S. aureus, Pseudomonas aeruginosa, and Ralstonia pickettii) and study the relationship among surface area, surface roughness, and bacterial growth.
    Results: Surface area measurement showed grouping of implants into high, intermediate, low, and minimal. Surface roughness showed a correlation with surface area. The in vitro assay showed a significant linear relationship between surface area and bacterial attachment/growth. The high surface area/roughness implant texture grew significantly more bacteria at 24 hours, whereas the minimal surface area/roughness implant textures grew significantly fewer bacteria of all types at 24 hours. For implants with intermediate and low surface areas, some species differences were observed, indicating possible affinity of specific bacterial species to surface morphology.
    Conclusions: Implant shells should be reclassified using surface area/roughness into four categories (high, intermediate, low, and minimal). This classification is superior to the use of descriptive terms such as macrotexture, microtexture, and nanotexture, which are not well correlated with objective measurement and/or functional outcomes.
    MeSH term(s) Bacteria/growth & development ; Bacterial Adhesion/physiology ; Breast Implants/microbiology ; Microscopy, Electron, Scanning ; Prosthesis Design ; Pseudomonas aeruginosa/growth & development ; Pseudomonas aeruginosa/physiology ; Ralstonia pickettii/growth & development ; Ralstonia pickettii/physiology ; Staphylococcus aureus/physiology ; Staphylococcus epidermidis/growth & development ; Staphylococcus epidermidis/physiology ; Structure-Activity Relationship ; Surface Properties
    Language English
    Publishing date 2018-09-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0000000000004801
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.142: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 293: Show issues

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  5. Article ; Online: Transmission of Staphylococcus aureus from dry surface biofilm (DSB) via different types of gloves.

    Tahir, Shamaila / Chowdhury, Durdana / Legge, Mark / Hu, Honghua / Whiteley, Greg / Glasbey, Trevor / Deva, Anand K / Vickery, Karen

    Infection control and hospital epidemiology

    2018  Volume 40, Issue 1, Page(s) 60–64

    Abstract: Background: Pathogens can survive for extended periods when incorporated into biofilm on dry hospital surfaces (ie, dry-surface biofilm, DSB). Bacteria within biofilm are protected from desiccation and have increased tolerance to cleaning agents and ... ...

    Abstract Background: Pathogens can survive for extended periods when incorporated into biofilm on dry hospital surfaces (ie, dry-surface biofilm, DSB). Bacteria within biofilm are protected from desiccation and have increased tolerance to cleaning agents and disinfectants.
    Objective: We hypothesized that gloved hands of healthcare personnel (HCP) become contaminated with DSB bacteria and hence may transmit bacteria associated with healthcare-associated infections (HAIs).
    Method: Staphylococcus aureus DSB was grown in vitro on coupons in a bioreactor over 12 days with periodic nutrition interspersed with long periods of dehydration. Each coupon had ~107 DSB bacterial cells. Transmission was tested with nitrile, latex, and surgical gloves by gripping DSB-covered coupons then pressing finger tips onto a sterile horse blood agar surface for up to 19 consecutive touches and counting the number of colony-forming units (CFU) transferred. Coupons were immersed in 5% neutral detergent to simulate cleaning, and the experiment was repeated.
    Results: Bacterial cells were readily transmitted by all 3 types of gloves commonly used by HCP. Surprisingly, sufficient S. aureus to cause infection were transferred from 1 DSB touch up to 19 consecutive touches. Also, 6 times more bacteria were transferred by nitrile and surgical gloves than to latex gloves (P <.001). Treating the DSB with 5% neutral detergent increased the transmission rate of DSB bacteria 10-fold.
    Conclusion: Staphylococcus aureus incorporated into environmental DSB and covered by extracellular polymeric substances readily contaminates gloved hands and can be transferred to another surface. These results confirm the possibility that DSB contributes to HAI acquisition.
    MeSH term(s) Biofilms ; Colony Count, Microbial ; Detergents/pharmacology ; Disinfectants/pharmacology ; Environmental Microbiology ; Fomites/microbiology ; Gloves, Protective/microbiology ; Gloves, Surgical/microbiology ; Health Personnel ; Humans ; Staphylococcus aureus/isolation & purification ; Surface Properties
    Chemical Substances Detergents ; Disinfectants
    Language English
    Publishing date 2018-11-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2018.285
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1714: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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