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  1. Book ; Thesis: Beurteilung des klinischen und radiologischen Outcomes von kniegelenksnahen modularen Tumorendoprothesen im Langzeitverlauf unter Berücksichtigung der subjektiven Patientenzufriedenheit

    Gippert, Sebastian / Merle, Christian

    2021  

    Institution Universität Heidelberg
    Author's details vorgelegt von Sebastian Gippert ; Doktorvater: Herr Prof. Dr. med. Christian Merle
    Language German
    Size 103 Blätter, Illustrationen, Diagramme, 30 cm
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2021
    HBZ-ID HT021233601
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 E 178 order for loan Magazin

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  2. Book: Klimawandel kompakt

    Schönwiese, Christian-Dietrich

    ein globales Problem wissenschaftlich erklärt

    2020  

    Author's details Christian-D. Schönwiese
    Keywords Klima ; Wetter ; Extremereignis ; Umwelt ; Klimaschutz ; Klimapolitik ; Klimaforschung ; Klimaänderung ; Anthropogene Klimaänderung ; Klimatologie
    Subject Klima ; Klimawandel ; Klimaveränderung ; Klimawechsel ; Klimaschutzpolitik ; Klimapolitik ; Klimaänderung ; Klimakunde ; Klimaforschung ; Mensch ; Klimapeioration ; Anthropogener Klimawandel
    Language German
    Size V, 132 Seiten, Illustrationen, Diagramme, Karten, Tabellen
    Edition 3. aktualisierte Auflage
    Publisher Borntraeger
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT020674443
    ISBN 978-3-443-01169-7 ; 3-443-01169-1
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    218/197 available for loan (reading room) Freihandmagazin (U1)

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  3. Article ; Online: Making smarter materials.

    Santangelo, Christian D

    Nature materials

    2022  

    Language English
    Publishing date 2022-11-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2088679-2
    ISSN 1476-4660 ; 1476-1122
    ISSN (online) 1476-4660
    ISSN 1476-1122
    DOI 10.1038/s41563-022-01408-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Geometric localization of waves on thin elastic structures.

    Mannattil, Manu / Santangelo, Christian D

    Physical review. E

    2024  Volume 109, Issue 3-2, Page(s) 35001

    Abstract: We consider the localization of elastic waves in thin elastic structures with spatially varying curvature profiles, using a curved rod and a singly curved shell as concrete examples. Previous studies on related problems have broadly focused on the ... ...

    Abstract We consider the localization of elastic waves in thin elastic structures with spatially varying curvature profiles, using a curved rod and a singly curved shell as concrete examples. Previous studies on related problems have broadly focused on the localization of flexural waves on such structures. Here, using the semiclassical WKB approximation for multicomponent waves, we show that in addition to flexural waves, extensional and shear waves also form localized, bound states around points where the absolute curvature of the structure has a minimum. We also see excellent agreement between our numerical experiments and the semiclassical results, which hinges on the vanishing of two extra phases that arise in the semiclassical quantization rule. Our findings open up novel ways to fine-tune the acoustic and vibrational properties of thin elastic structures and raise the possibility of introducing new phenomena not easily captured by effective models of flexural waves alone.
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.109.035001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Peer-reviewed presentation exchange in an undergraduate classroom.

    Kiselyov, Kirill / Schunn, Christian D

    Journal of microbiology & biology education

    2024  Volume 25, Issue 1, Page(s) e0006723

    Abstract: Reading, presenting, and discussing peer-reviewed scientific reports, case studies, and reviews are essential to modern biology education. These exercises model crucial aspects of students' future professional activities and introduce the students to the ...

    Abstract Reading, presenting, and discussing peer-reviewed scientific reports, case studies, and reviews are essential to modern biology education. These exercises model crucial aspects of students' future professional activities and introduce the students to the current scientific concepts and methodology, data analysis, and presentation. A common format for working with primary literature is a journal club: presenting and discussing research literature in front of peers, which has many merits. However, in large modern classrooms, this format is very time-consuming and stressful, especially since presenting is not a commonly taught skill. We argue that student groups for whom the current educational and professional paradigms present a challenge due to a historical lack of representation or wellness issues are deprived of a key educational opportunity. To solve this problem, we formulated an approach called Peer-Reviewed Presentation Exchange (PRPE), which focuses on collaborative analysis, presentation, and review of research literature that includes (i) voice-narrated research presentations by students, (ii) checklists generated by the instructor to establish expectations for an informative presentation or review, and (iii) presentation assignment and peer review process. We tested this approach in an undergraduate cell biology class over 3 years. Pre- and post-assessments show significant gains in self-efficacy and knowledge not only by students who presented but also by the students who reviewed the presentations; therefore, peer-reviewed presentations are an effective tool for learning. Exit surveys show that the approach is seen as beneficial by most students. Our approach allows every student to speak and ask questions in a low-stress creative environment. It is an excellent customizable, trackable, and scalable low-stakes assessment tool.
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Journal Article
    ISSN 1935-7877
    ISSN 1935-7877
    DOI 10.1128/jmbe.00067-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Satellite precipitation measurement / Volume 2

    Levizzani, Vincenzo / Kidd, Christopher / Kirschbaum, Dalia B. / Kummerow, Christian D. / Nakamura, Kenji / Turk, Joseph F.

    (Advances in global change research ; Volume 69)

    2020  

    Author's details Vincenzo Levizzani, Christopher Kidd, Dalia B. Kirschbaum, Christian D. Kummerow, Kenji Nakamura, F. Joseph Turk, editors
    Series title Advances in global change research ; Volume 69
    Satellite precipitation measurement
    Collection Satellite precipitation measurement
    Language English
    Size xciii, Seite 453 - Seite 1176, Illustrationen, Diagramme (teils farbig), Karten (teils farbig)
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT020439711
    ISBN 978-3-030-35797-9 ; 9783030357986 ; 3-030-35797-X ; 3030357988
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    208/29 available for loan (reading room) Freihandmagazin (U1)

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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  7. Book: Satellite precipitation measurement / Volume 1

    Levizzani, Vincenzo / Kidd, Christopher / Kirschbaum, Dalia B. / Kummerow, Christian D. / Nakamura, Kenji / Turk, Joseph F.

    (Advances in global change research ; Volume 67)

    2020  

    Author's details Vincenzo Levizzani, Christopher Kidd, Dalia B. Kirschbaum, Christian D. Kummerow, Kenji Nakamura, F. Joseph Turk, editors
    Series title Advances in global change research ; Volume 67
    Satellite precipitation measurement
    Collection Satellite precipitation measurement
    Language English
    Size lxxi, 450 Seiten, Illustrationen, Diagramme, Karten
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT020439691
    ISBN 978-3-030-24567-2 ; 9783030245689 ; 3-030-24567-5 ; 3030245683
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    208/28 available for loan (reading room) Freihandmagazin (U1)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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  8. Book ; Collection: Satellite precipitation measurement

    Levizzani, Vincenzo / Kidd, Christopher / Kirschbaum, Dalia B. / Kummerow, Christian D. / Nakamura, Kenji / Turk, Joseph F.

    (Advances in global change research)

    2020  

    Author's details Vincenzo Levizzani, Christopher Kidd, Dalia B. Kirschbaum, Christian D. Kummerow, Kenji Nakamura, F. Joseph Turk, editors
    Series title Advances in global change research
    Keywords Satellitenfernerkundung ; Niederschlag
    Subject Satellit
    Language English
    Dates of publication 2020-2020
    Publisher Springer International Publishing
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Collection (display volumes)
    HBZ-ID HT020439684
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  9. Book ; Online: Determinants of synaptic information transfer: From Ca2+ binding proteins to Ca2+ signaling domains

    Schmidt, Hartmut / Wilms, Christian D. / Isope, Philippe

    2016  

    Abstract: The cytoplasmic free Ca2+ concentration ([Ca2+]i) is a key determinant of neuronal information transfer and processing. It controls a plethora of fundamental processes, including transmitter release and the induction of synaptic plasticity. This ... ...

    Abstract The cytoplasmic free Ca2+ concentration ([Ca2+]i) is a key determinant of neuronal information transfer and processing. It controls a plethora of fundamental processes, including transmitter release and the induction of synaptic plasticity. This enigmatic second messenger conveys its wide variety of actions by binding to a subgroup of Ca2+ binding proteins (CaBPs) known as "Ca2+ sensors". Well known examples of Ca2+ sensors are Troponin-C in skeletal muscle, Synaptotagmin in presynaptic terminals, and Calmodulin (CaM) in all eukaryotic cells. Since the levels of [Ca2+]i directly influence the potency of Ca2+ sensors, the Ca2+ concentration is tightly controlled by several mechanisms including another type of Ca2+ binding proteins, the Ca2+ buffers. Prominent examples of Ca2+ buffers include Parvalbumin (PV), Calbindin-D28k (CB) and Calretinin (CR), although for the latter two Ca2+ sensor functions were recently also suggested.-

    Ca2+ buffers are distinct from sensors by their purely buffering action, i.e. they influence the spatio-temporal extent of Ca2+ signals, without directly binding downstream target proteins. Details of their action depend on their binding kinetics, mobility, and concentration. Thus, neurons can control the range of action of Ca2+ by the type and concentration of CaBPs expressed. Since buffering strongly limits the range of action of free Ca2+, the structure of the Ca2+ signaling domain and the topographical relationships between the sites of Ca2+ influx and the location of the Ca2+ sensors are central determinants in neuronal information processing. For example, postsynaptic dendritic spines act to compartmentalize Ca2+ depending on their geometry and expression of CaBPs, thereby influencing dendritic integration.-

    At presynaptic sites it has been shown that tight, so called nanodomain coupling between Ca2+ channels and the sensor for vesicular transmitter release increases speed and reliability of synaptic transmission. Vice versa, the influence of an individual CaBP on information processing depends on the topographical relationships within the signaling domain. If e.g. source and sensor are very close, only buffers with rapid binding kinetics can interfere with signaling. This Research Topic contains a collection of work dealing with the relationships between different [Ca2+]i controlling mechanisms in the structural context of synaptic sites and their functional implications for synaptic information processing as detailed in the Editorial
    Keywords Neurosciences. Biological psychiatry. Neuropsychiatry ; Science (General)
    Size 1 electronic resource (133 p.)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020090557
    ISBN 9782889198344 ; 2889198340
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  10. Book ; Online: Generating Bayesian Network Models from Data Using Tsetlin Machines

    Blakely, Christian D.

    2023  

    Abstract: Bayesian networks (BN) are directed acyclic graphical (DAG) models that have been adopted into many fields for their strengths in transparency, interpretability, probabilistic reasoning, and causal modeling. Given a set of data, one hurdle towards using ... ...

    Abstract Bayesian networks (BN) are directed acyclic graphical (DAG) models that have been adopted into many fields for their strengths in transparency, interpretability, probabilistic reasoning, and causal modeling. Given a set of data, one hurdle towards using BNs is in building the network graph from the data that properly handles dependencies, whether correlated or causal. In this paper, we propose an initial methodology for discovering network structures using Tsetlin Machines.
    Keywords Computer Science - Artificial Intelligence
    Publishing date 2023-05-17
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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