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  1. Article: Origin of the Thiopyrone CTP-431 “Unexpectedly” Isolated from the Marine Sponge Cacospongia mycofijiensis

    Przeslak, Adam D / Christopher J. Moody / Martyn Inman / William Lewis

    Journal of organic chemistry. 2018 July 25, v. 83, no. 17

    2018  

    Abstract: An intriguing hypothesis that latrunculin A, a well-known natural product, might have undergone transformation into the unprecedented thiopyrone CTP-431 upon long-term storage in methanol is advanced. Thus, opening of the hemiacetal of latrunculin A, ... ...

    Abstract An intriguing hypothesis that latrunculin A, a well-known natural product, might have undergone transformation into the unprecedented thiopyrone CTP-431 upon long-term storage in methanol is advanced. Thus, opening of the hemiacetal of latrunculin A, followed by E1CB elimination, and dehydration would give a polyene that could undergo intramolecular Diels–Alder reaction, followed by methanolysis of the thiazolidinone ring and ring closure by intramolecular thiol addition to an enone. Experimental evidence that the novel thiazolidinone to thiopyrone rearrangement can occur is presented.
    Keywords chemical structure ; methanol ; methanolysis ; organic chemistry ; Porifera ; storage ; thiols
    Language English
    Dates of publication 2018-0725
    Size p. 10595-10601.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.8b01258
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

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  2. Article: Sustainable, mild and efficient p-methoxybenzyl ether deprotections utilizing catalytic DDQ

    Walsh, Katie / Christopher J. Moody / Helen F. Sneddon

    Tetrahedron. 2014 Oct. 07, v. 70

    2014  

    Abstract: A procedure for the selective deprotection of p-methoxybenzyl ethers using catalytic amounts of DDQ and of sodium nitrite, with oxygen as the terminal oxidant, is reported. ...

    Abstract A procedure for the selective deprotection of p-methoxybenzyl ethers using catalytic amounts of DDQ and of sodium nitrite, with oxygen as the terminal oxidant, is reported.
    Keywords chemical reactions ; chemical structure ; ethers ; oxidants ; oxygen ; sodium nitrite
    Language English
    Dates of publication 2014-1007
    Size p. 7380-7387.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 204285-x
    ISSN 1464-5416 ; 0040-4020 ; 0563-2064
    ISSN (online) 1464-5416
    ISSN 0040-4020 ; 0563-2064
    DOI 10.1016/j.tet.2014.07.003
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1076: Show issues Location:
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  3. Article: Synthesis of 6-arylisocytosines and their potential for hydrogen bonding interactions

    Patel, Alpa / Christopher J. Moody / Malcolm F.G. Stevens / Mark S. Searle / William Lewis

    Tetrahedron. 2015 Sept. 30, v. 71

    2015  

    Abstract: The synthesis of a number of 6-arylisocytosines, including linked bis-isocytosines, from the reaction of guanidine with β-ketoesters is described. The compounds were investigated for their ability to form hydrogen-bonded structural networks, and for ... ...

    Abstract The synthesis of a number of 6-arylisocytosines, including linked bis-isocytosines, from the reaction of guanidine with β-ketoesters is described. The compounds were investigated for their ability to form hydrogen-bonded structural networks, and for their potential interactions with the telomeric quadruplex forming sequence AGGG(TTAGGG)3.
    Keywords chemical reactions ; chemical structure ; guanidines ; hydrogen bonding ; nucleotide sequences ; telomeres
    Language English
    Dates of publication 2015-0930
    Size p. 7339-7343.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 204285-x
    ISSN 1464-5416 ; 0040-4020 ; 0563-2064
    ISSN (online) 1464-5416
    ISSN 0040-4020 ; 0563-2064
    DOI 10.1016/j.tet.2015.04.084
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

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  4. Article ; Online: An expedient approach to the 2,3,5,6-tetrasubstituted pyridine core of nosiheptide using oxidative cleavage of 2,3,5,8-tetrasubstituted quinolines

    David Taddei / Cyril Poriel / Christopher J. Moody

    ARKIVOC, Vol 2007, Iss 11, Pp 56-

    2006  Volume 63

    Keywords Organic chemistry ; QD241-441
    Language English
    Publishing date 2006-09-01T00:00:00Z
    Publisher Arkat USA, Inc.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Synthesis of toxyloxanthone B

    Giallombardo, Daniele / Adam C. Nevin / Christopher C. Nawrat / Christopher J. Moody / Russell R.A. Kitson / William Lewis

    Tetrahedron. 2014 Feb. 11, v. 70

    2014  

    Abstract: A synthesis of the naturally occurring xanthone toxyloxanthone B is described, in which the key step is the regioselective addition of a methyl salicylate to a substituted benzyne, followed by cyclization of the intermediate aryl anion to form the ... ...

    Abstract A synthesis of the naturally occurring xanthone toxyloxanthone B is described, in which the key step is the regioselective addition of a methyl salicylate to a substituted benzyne, followed by cyclization of the intermediate aryl anion to form the xanthone, the regiochemistry of the aryne addition being confirmed by X-ray crystallography. Subsequent introduction of the pyran ring by [3,3]-rearrangement and deprotection completed the synthesis.
    Keywords chemical reactions ; chemical structure ; methyl salicylate ; xanthone ; X-ray diffraction
    Language English
    Dates of publication 2014-0211
    Size p. 1283-1288.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 204285-x
    ISSN 1464-5416 ; 0040-4020 ; 0563-2064
    ISSN (online) 1464-5416
    ISSN 0040-4020 ; 0563-2064
    DOI 10.1016/j.tet.2013.12.055
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1076: Show issues Location:
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  6. Article ; Online: Iodocyclisation of N-allyl ureas; a route to imidazolin-2-ones

    Christopher J. Moody / Peter A. Hunt / Colin Smith

    ARKIVOC, Vol 2000, Iss 5, Pp 698-

    2000  Volume 706

    Keywords Organic chemistry ; QD241-441
    Language English
    Publishing date 2000-10-01T00:00:00Z
    Publisher Arkat USA, Inc.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Synthesis of N-protected nortopsentins B and D

    Christopher J. Moody / Jonathan R. A. Roffey

    ARKIVOC, Vol 2000, Iss 3, Pp 393-

    2000  Volume 401

    Keywords Organic chemistry ; QD241-441
    Language English
    Publishing date 2000-08-01T00:00:00Z
    Publisher Arkat USA, Inc.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: N-H Insertion reactions of rhodium carbenoids. Part 4. New chiral dirhodium(II) carboxylate catalysts

    Richard T. Buck / Christopher J. Moody / Adrian G. Pepper

    ARKIVOC, Vol 2002, Iss 8, Pp 16-

    2002  Volume 33

    Keywords Organic chemistry ; QD241-441
    Language English
    Publishing date 2002-06-01T00:00:00Z
    Publisher Arkat USA, Inc.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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