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Article: Testicular torsion in a newborn: a case report.

Blevrakis, E / Xenaki, S / Chrysos, E

2019 Volume 40, Issue 1, Page(s) 54–57

Abstract: Discovery of an apparent scrotal mass is a non common entity in neonates. Testicular torsion is rare in newborn infants and is an urologic emergency that requires emergency surgical management. We present a rare case of testicular torsion in a neonate. ...

Abstract	Discovery of an apparent scrotal mass is a non common entity in neonates. Testicular torsion is rare in newborn infants and is an urologic emergency that requires emergency surgical management. We present a rare case of testicular torsion in a neonate.
MeSH term(s)	Early Diagnosis ; Humans ; Infant, Newborn ; Male ; Necrosis/etiology ; Necrosis/surgery ; Orchiectomy ; Orchiopexy ; Spermatic Cord/pathology ; Spermatic Cord Torsion/diagnostic imaging ; Spermatic Cord Torsion/surgery ; Testis/pathology ; Ultrasonography
Language	English
Publishing date	2019-02-10
Publishing country	Italy
Document type	Case Reports ; Journal Article
ZDB-ID	605974-0
ISSN	1971-145X ; 0391-9005
ISSN (online)	1971-145X
ISSN	0391-9005
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Article ; Online: Coexistance of a well differentiated liposarcoma and dedifferentiated low grade myxofibrosarcoma of the scrotum. A rare case and review of the literature.

Xenaki, S / Panagiotakis, G / Lagoudaki, H / Tzardi, M / Chrysos, E / Petrakis, J

Il Giornale di chirurgia

2020 Volume 40, Issue 6, Page(s) 526–529

Abstract: Liposarcoma is a malignant soft tissue sarcoma usually located in the thigh or the posterior peritoneum in an adult. However, the occurrence of liposarcoma, and indeed a coexistance with scrotal myxofibrosarcoma, is rare. We present an interesting case ... ...

Abstract	Liposarcoma is a malignant soft tissue sarcoma usually located in the thigh or the posterior peritoneum in an adult. However, the occurrence of liposarcoma, and indeed a coexistance with scrotal myxofibrosarcoma, is rare. We present an interesting case of a 56-year old male who presented with an inguinal hernia. During the operation a massive fibro-elastic mass located within the left scrotum was noticed which deposited the testicle upward by displacing it into a sack rather than the penis. The mass did not come into contact with the spermatic cord but alongside it the existence of the blood vessels of the mass was found. The histopathological examination revealed a well differentiated liposarcoma along with dedifferentiated low grade myxofibrosarcoma.
MeSH term(s)	Fibrosarcoma/pathology ; Fibrosarcoma/surgery ; Genital Neoplasms, Male/pathology ; Genital Neoplasms, Male/surgery ; Humans ; Liposarcoma/pathology ; Liposarcoma/surgery ; Male ; Middle Aged ; Neoplasms, Multiple Primary/pathology ; Neoplasms, Multiple Primary/surgery ; Scrotum
Language	English
Publishing date	2020-01-30
Publishing country	Italy
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	605974-0
ISSN	1971-145X ; 0391-9005
ISSN (online)	1971-145X
ISSN	0391-9005
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Article: External Validation of the American College of Surgeons Surgical Risk Calculator in Elderly Patients Undergoing General Surgery Operations.

Kokkinakis, Stamatios / Andreou, Alexandros / Venianaki, Maria / Chatzinikolaou, Charito / Chrysos, Emmanuel / Lasithiotakis, Konstantinos

Journal of clinical medicine

2022 Volume 11, Issue 23

Abstract: Preoperative risk stratification in the elderly surgical patient is an essential part of contemporary perioperative care and can be done with the use of the American College of Surgeons Surgical Risk Calculator (ACS-SRC). However, data on the ... ...

Abstract	Preoperative risk stratification in the elderly surgical patient is an essential part of contemporary perioperative care and can be done with the use of the American College of Surgeons Surgical Risk Calculator (ACS-SRC). However, data on the generalizability of the ACS-SRC in the elderly is scarce. In this study, we report an external validation of the ACS-RC in a geriatric cohort. A retrospective analysis of a prospectively maintained database was performed including patients aged > 65 who underwent general surgery procedures during 2012−2017 in a Greek academic centre. The predictive ability of the ACS-SRC for post-operative outcomes was tested with the use of Brier scores, discrimination, and calibration metrics. 471 patients were included in the analysis. 30-day postoperative mortality was 3.2%. Overall, Brier scores were lower than cut-off values for almost all outcomes. Discrimination was good for serious complications (c-statistic: 0.816; 95% CI: 0.762−0.869) and death (c-statistic: 0.824; 95% CI: 0.719−0.929). The Hosmer-Lemeshow test showed good calibration for all outcomes examined. Predicted and observed length of stay (LOS) presented significant differences for emergency and for elective cases. The ACS-SRC demonstrated good predictive performance in our sample and can aid preoperative estimation of multiple outcomes except for the prediction of post-operative LOS.
Language	English
Publishing date	2022-11-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm11237083
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Article ; Online: Regarding: Comparative Outcomes of Open Abdominal Therapy After Ruptured Abdominal Aortic Aneurysm via Open and Endovascular Approaches.

Kontopodis, Nikolaos / Lasithiotakis, Konstantinos / Tzartzalou, Ifigeneia / Chrysos, Emmanuel / Ioannou, Christos V

Annals of vascular surgery

2022 Volume 85, Page(s) e2–e3

MeSH term(s)	Abdomen ; Aortic Aneurysm, Abdominal/diagnostic imaging ; Aortic Aneurysm, Abdominal/surgery ; Aortic Rupture/diagnostic imaging ; Aortic Rupture/surgery ; Blood Vessel Prosthesis Implantation/adverse effects ; Endovascular Procedures/adverse effects ; Humans ; Risk Factors ; Treatment Outcome
Language	English
Publishing date	2022-06-02
Publishing country	Netherlands
Document type	Letter
ZDB-ID	1027366-9
ISSN	1615-5947 ; 0890-5096
ISSN (online)	1615-5947
ISSN	0890-5096
DOI	10.1016/j.avsg.2022.05.008
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Article: Medicinal plants in the treatment of urinary tract malignancies during the Araboislamic period (7

Drogosis, Achillefs / Mamoulakis, Charalampos / Chrysos, Emmanuel / Tsoucalas, Gregory / Michaleas, Spyros N / Karamanou, Marianna

Arab journal of urology

2022 Volume 20, Issue 4, Page(s) 219–223

Abstract: Arabic medicine, or Arab-Islamic, mainly refers to all developments achieved in the Age of Khalifs, or the Golden Age of the Arab-Islamic civilization (ca ... ...

Abstract	Arabic medicine, or Arab-Islamic, mainly refers to all developments achieved in the Age of Khalifs, or the Golden Age of the Arab-Islamic civilization (ca 7
Language	English
Publishing date	2022-05-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2631788-6
ISSN	2090-598X
ISSN	2090-598X
DOI	10.1080/2090598X.2022.2077002
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Article: Complications of modern pancreaticoduodenectomy: A systematic review and meta-analysis.

Kokkinakis, Stamatios / Kritsotakis, Evangelos I / Maliotis, Neofytos / Karageorgiou, Ioannis / Chrysos, Emmanuel / Lasithiotakis, Konstantinos

Hepatobiliary & pancreatic diseases international : HBPD INT

2022 Volume 21, Issue 6, Page(s) 527–537

Abstract: Background: In the past decades, the perioperative management of patients undergoing pancreaticoduodenectomy (PD) has undergone major changes worldwide. This review aimed to systematically determine the burden of complications of PD performed in the ... ...

Abstract	Background: In the past decades, the perioperative management of patients undergoing pancreaticoduodenectomy (PD) has undergone major changes worldwide. This review aimed to systematically determine the burden of complications of PD performed in the last 10 years. Data sources: A systematic review was conducted in PubMed for randomized controlled trials and observational studies reporting postoperative complications in at least 100 PDs from January 2010 to April 2020. Risk of bias was assessed using the Cochrane RoB2 tool for randomized studies and the methodological index for non-randomized studies (MINORS). Pooled complication rates were estimated using random-effects meta-analysis. Heterogeneity was investigated by subgroup analysis and meta-regression. Results: A total of 20 randomized and 49 observational studies reporting 63 229 PDs were reviewed. Mean MINORS score showed a high risk of bias in non-randomized studies, while one quarter of the randomized studies were assessed to have high risk of bias. Pooled incidences of 30-day mortality, overall complications and serious complications were 1.7% (95% CI: 0.9%-2.9%; I Conclusions: Pooled complication rates estimated in this study may be used to counsel patients scheduled to undergo a PD and to set benchmarks against which centers can audit their practice. However, cautious interpretation is necessary due to substantial heterogeneity.
MeSH term(s)	Humans ; Pancreaticoduodenectomy/adverse effects ; Pancreatectomy ; Pancreatic Fistula/epidemiology ; Pancreatic Fistula/etiology ; Pancreas ; Postoperative Complications/etiology ; Postoperative Complications/epidemiology
Language	English
Publishing date	2022-04-25
Publishing country	Singapore
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	2241386-8
ISSN	1499-3872
ISSN	1499-3872
DOI	10.1016/j.hbpd.2022.04.006
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Article: Early Postoperative Parathormone and Calcium as Prognostic Factors for Postoperative Hypocalcemia.

Daskalaki, Anna / Xenaki, Sofia / Lasithiotakis, Konstantinos / Chrysos, Alexandros / Kampa, Marilena / Notas, George / Chrysos, Emmanuel

Journal of clinical medicine

2022 Volume 11, Issue 9

Abstract: Background: Postoperative hypocalcemia is one of the most common complications after total thyroidectomy. Parathormone (PTH) and calcium levels, measured several hours after surgery, have been suggested as valuable markers for detecting patients at risk ...

Abstract	Background: Postoperative hypocalcemia is one of the most common complications after total thyroidectomy. Parathormone (PTH) and calcium levels, measured several hours after surgery, have been suggested as valuable markers for detecting patients at risk for post-thyroidectomy hypocalcemia. We aimed to determine if early post-surgery PTH and calcium levels can be used for the early identification of patients at risk for symptomatic hypocalcemia. Methods: PTH and calcium were measured before surgery and at 10 min and 4 h post-thyroidectomy, in 77 patients. Performance characteristics of PTH and calcium levels and their post/pre-surgery ratios were calculated. Results: Four-hour calcium was a sensitive (93.75%) but not specific (67.61%) indicator of patients at risk for symptomatic hypocalcemia. The 4-h/pre-surgery PTH ratio was the most accurate (90.81%) and the most specific (94.37%) test to identify patients at risk. Serum calcium at 4-h, 4-h/pre-surgery PTH ratio, and PTH at 10 min post-surgery had the higher diagnostic odds ratios (50.86, 32.85, and 29.04, respectively). The 4-h/pre-surgery PTH ratio also had the highest (0.694) Youden's J statistic. Conclusions: Low serum calcium levels 4 h after thyroidectomy and the 4-h/pre-surgery PTH ratio could be valuable additions to everyday clinical practice in post-thyroidectomy patients.
Language	English
Publishing date	2022-04-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm11092389
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Article: Correction: Daskalaki et al. Early Postoperative Parathormone and Calcium as Prognostic Factors for Postoperative Hypocalcemia.

Daskalaki, Anna / Xenaki, Sofia / Lasithiotakis, Konstantinos / Chrysos, Alexandros / Kampa, Marilena / Notas, George / Chrysos, Emmanuel

Journal of clinical medicine

2022 Volume 11, Issue 24

Abstract: In the published article [ ... ]. ...

Abstract	In the published article [...].
Language	English
Publishing date	2022-12-08
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm11247280
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Article: Does the Routine Skin-Only Closure in Ruptured Abdominal Aortic Aneurysm Repair Safely Diminish Abdominal Compartment Syndrome? A Hypothesis Generating Retrospective Study.

Kontopodis, Nikolaos / Lasithiotakis, Konstantinos / Tzartzalou, Ifigeneia / Kasiolas, Ioannis / Kafetzakis, Alexandros / Chrysos, Emmanuel / Ioannou, Christos V

Aorta (Stamford, Conn.)

2023 Volume 11, Issue 2, Page(s) 57–62

Abstract: Background: Abdominal compartment syndrome (ACS) often complicates ruptured abdominal aortic aneurysm (rAAA) repair. We report results with routine skin-only abdominal wound closure after rAAA surgical repair.: Methods: This was a single-center ... ...

Abstract	Background: Abdominal compartment syndrome (ACS) often complicates ruptured abdominal aortic aneurysm (rAAA) repair. We report results with routine skin-only abdominal wound closure after rAAA surgical repair. Methods: This was a single-center retrospective study including consecutive patients undergoing rAAA surgical repair for the duration of 7 years. Skin-only closure was routinely performed, and if possible, secondary abdominal closure was performed during the same admission. Demographic information, preoperative hemodynamic condition, and perioperative information (ACS, mortality, rate of abdominal closure, and postoperative outcomes) were collected. Results: During the study period, 93 rAAAs were recorded. Ten patients were too frail to undergo repair or refused treatment. Eighty-three patients underwent immediate surgical repair. The mean age was 72.4 ± 10.5 years, and the vast majority were male (82:1). Preoperative systolic blood pressure <90 mm Hg was recorded in 31 patients. Intraoperative mortality was recorded in nine cases. Overall in-hospital mortality was 34.9% (29/83). Primary fascial closure was performed in five patients, while skin-only closure was performed in 69. ACS was recorded in two cases in whom skin sutures were removed and negative pressure wound treatment was applied. Secondary fascial closure was feasible in 30 patients during the same admission. Among 37 patients not undergoing fascial closure, 18 died and 19 survived and were discharged with a planned ventral hernia repair. Median length of intensive care unit and hospital stay were 5 (1-24) and 13 (8-35) days, respectively. After a mean follow-up of 21 months, telephone contact was possible with 14/19 patients who left the hospital with an abdominal hernia. Three reported hernia-related complications mandating surgical repair, while in 11, this was well tolerated. Conclusion: Routine skin-only closure during rAAA surgical repair results in low rates of ACS at the expense of a high rate of patients being discharged with a planned ventral hernia which, however, seems to be well tolerated by the majority of patients.
Language	English
Publishing date	2023-04-13
Publishing country	Germany
Document type	Journal Article
ISSN	2325-4637
ISSN	2325-4637
DOI	10.1055/a-2066-8480
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Article: A Comparison of the Malnutrition Universal Screening Tool (MUST) and the Mini Nutritional Assessment-Short Form (MNA-SF) Tool for Older Patients Undergoing General Surgery.

Kokkinakis, Stamatios / Venianaki, Maria / Petra, Georgia / Chrysos, Alexandros / Chrysos, Emmanuel / Lasithiotakis, Konstantinos

Journal of clinical medicine

2021 Volume 10, Issue 24

Abstract: The optimal malnutrition screening tool in geriatric surgery has yet to be determined. Herein, we compare two main tools in older patients undergoing general surgery operations. Older patients (>65 years old) who underwent general surgery operations ... ...

Abstract	The optimal malnutrition screening tool in geriatric surgery has yet to be determined. Herein, we compare two main tools in older patients undergoing general surgery operations. Older patients (>65 years old) who underwent general surgery operations between 2012 and 2017 in a tertiary centre were included. The Malnutrition Universal Screening Tool (MUST) and the Mini Nutritional Assessment Short Form (MNA-SF) were used for nutritional risk assessment. Preoperative variables as well as postoperative outcomes were recorded prospectively. Agreement between tools was determined with the weighted kappa (κ) statistic. Multiple regression analysis was used to assess the association of the screening tools with postoperative outcomes. A total of 302 patients (median age 74 years, range: 65-92) were included. A similar number of patients were classified as medium/high risk for malnutrition with the MNA-SF and MUST (26% vs. 36%,
Language	English
Publishing date	2021-12-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm10245860
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