LIVIVO - Search results -

Search results

Result 1 - 10 of total 88

Search options

Article ; Online: A rare case of COVID-19 infection with laryngeal involvement.

Asaoka, Masato / Chubachi, Shotaro / Yamada, Yoshitake / Fukunaga, Koichi

BMJ case reports

2021 Volume 14, Issue 6

MeSH term(s)	COVID-19 ; Humans ; Larynx/diagnostic imaging ; Lung ; SARS-CoV-2
Language	English
Publishing date	2021-06-04
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2021-242426
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: [Bone turnover and bone structure in clinical animal models of COPD.]

Sasaki, Mamoru / Chubachi, Shotaro

Clinical calcium

2016 Volume 26, Issue 10, Page(s) 1413–1418

Abstract: The features of chronic obstructive pulmonary disease(COPD)are chronic inflammatory and emphysema changes in the lungs by long-term cigarette smoke(CS)exposure. Osteoporosis is an important systemic comorbidity of COPD. Severe emphysema and low body mass ...

Abstract	The features of chronic obstructive pulmonary disease(COPD)are chronic inflammatory and emphysema changes in the lungs by long-term cigarette smoke(CS)exposure. Osteoporosis is an important systemic comorbidity of COPD. Severe emphysema and low body mass index(BMI)are independent risk factors for low bone mineral density in COPD patients. However the pathophysiologic mechanisms underlying emphysema and osteoporosis have not been fully elucidated. An established mouse model of CS-induced emphysema with decrease body weight and bone mineral density is important for investigating the cause of osteoporosis in COPD patients.
MeSH term(s)	Animals ; Bone Density/physiology ; Bone and Bones/physiology ; Disease Models, Animal ; Humans ; Osteoporosis/complications ; Osteoporosis/diagnosis ; Pulmonary Disease, Chronic Obstructive/complications ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Emphysema/complications ; Pulmonary Emphysema/diagnosis
Language	Japanese
Publishing date	2016
Publishing country	Japan
Document type	Journal Article ; Review
ZDB-ID	2386417-5
ISSN	0917-5857
ISSN	0917-5857
DOI	CliCa161014131418
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6536: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Differences in lung and lobe volumes between supine and upright computed tomography in patients with idiopathic lung fibrosis.

Chubachi, Shotaro / Okamori, Satoshi / Yamada, Yoshitake / Yamada, Minoru / Yokoyama, Yoichi / Niijima, Yuki / Kamata, Hirofumi / Ishii, Makoto / Fukunaga, Koichi / Jinzaki, Masahiro

Scientific reports

2022 Volume 12, Issue 1, Page(s) 19408

Abstract: No clinical study has compared lung or lobe volumes on computed tomography (CT) between the supine and standing positions in patients with idiopathic lung fibrosis (IPF). This study aimed to compare lung and lobe volumes between the supine and standing ... ...

Abstract	No clinical study has compared lung or lobe volumes on computed tomography (CT) between the supine and standing positions in patients with idiopathic lung fibrosis (IPF). This study aimed to compare lung and lobe volumes between the supine and standing positions and evaluate the correlations between the supine/standing lung volumes on CT and pulmonary function in patients with IPF. Twenty-three patients with IPF underwent a pulmonary function test and both low-dose conventional (supine position) and upright CT (standing position) during inspiration breath-holds. The volumes of the total lungs and lobes were larger in the standing than in the supine position in patients with IPF (all p < 0.05). Spearman's correlation coefficients between total lung volumes on chest CT in supine/standing positions and vital capacity (VC) or forced VC (FVC) were 0.61/0.79 or 0.64/0.80, respectively. CT-based volumes on upright CT were better correlated with VC and FVC than those on supine CT. Lung and lobe volumes in the standing position may be useful biomarkers to assess disease severity or therapeutic effect in patients with IPF.
MeSH term(s)	Humans ; Standing Position ; Idiopathic Pulmonary Fibrosis/diagnostic imaging ; Respiratory Function Tests ; Lung/diagnostic imaging ; Tomography, X-Ray Computed/methods
Language	English
Publishing date	2022-11-12
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-24157-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Successful Steroid Treatment of Pembrolizumab-induced Agranulocytosis That Developed after Splenectomy in a Patient with Non-small-cell Lung Cancer.

Okuzumi, Shinichi / Kamata, Hirofumi / Emoto, Katsura / Shimizu, Takayuki / Otake, Shiro / Irie, Hidehiro / Chubachi, Shotaro / Ikemura, Shinnosuke / Yasuda, Hiroyuki / Fukunaga, Koichi

Internal medicine (Tokyo, Japan)

2022 Volume 62, Issue 14, Page(s) 2113–2121

Abstract: Neutropenia, a rare immune-related adverse event, affects patients receiving treatment with immune checkpoint inhibitors (ICIs). We herein report a case of pembrolizumab-induced agranulocytosis. An 83-year-old man was diagnosed with advanced-stage lung ... ...

Abstract	Neutropenia, a rare immune-related adverse event, affects patients receiving treatment with immune checkpoint inhibitors (ICIs). We herein report a case of pembrolizumab-induced agranulocytosis. An 83-year-old man was diagnosed with advanced-stage lung carcinoma concomitant with splenomegaly complicated by hypersplenism, causing pancytopenia. To avoid the risk of bone marrow suppression due to cytotoxic chemotherapy, pembrolizumab monotherapy was chosen. However, the patient developed agranulocytosis despite the resolution of pancytopenia through splenectomy performed after the fourth pembrolizumab cycle. Neutrophil counts improved after steroid treatment but not after granulocyte colony-stimulating factor treatment. This case demonstrated that neutropenia can sometimes develop abruptly after several ICI therapy cycles.
MeSH term(s)	Male ; Humans ; Aged, 80 and over ; Carcinoma, Non-Small-Cell Lung/complications ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/surgery ; Lung Neoplasms/complications ; Lung Neoplasms/drug therapy ; Lung Neoplasms/surgery ; Pancytopenia ; Splenectomy ; Antineoplastic Agents, Immunological/adverse effects ; Neutropenia/chemically induced ; Steroids/therapeutic use
Chemical Substances	pembrolizumab (DPT0O3T46P) ; Antineoplastic Agents, Immunological ; Steroids
Language	English
Publishing date	2022-11-30
Publishing country	Japan
Document type	Case Reports ; Journal Article
ZDB-ID	32371-8
ISSN	1349-7235 ; 0021-5120 ; 0918-2918
ISSN (online)	1349-7235
ISSN	0021-5120 ; 0918-2918
DOI	10.2169/internalmedicine.0278-22
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 240: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Comparison of Lung, Lobe, and Airway Volumes between Supine and Upright Computed Tomography and Their Correlation with Pulmonary Function Test in Patients with Chronic Obstructive Pulmonary Disease.

Yamada, Yoshitake / Chubachi, Shotaro / Yamada, Minoru / Yokoyama, Yoichi / Tanabe, Akiko / Matsuoka, Shiho / Niijima, Yuki / Murata, Mitsuru / Fukunaga, Koichi / Jinzaki, Masahiro

Respiration; international review of thoracic diseases

2022 Volume 101, Issue 12, Page(s) 1110–1120

Abstract: Background: Correlations between upright CT and pulmonary function test (PFT) measurements, and differences in lung/lobe/airway volumes between supine and standing positions in patients with chronic obstructive pulmonary disease (COPD) remain unknown.!## ...

Abstract	Background: Correlations between upright CT and pulmonary function test (PFT) measurements, and differences in lung/lobe/airway volumes between supine and standing positions in patients with chronic obstructive pulmonary disease (COPD) remain unknown. Objectives: The study aimed to evaluate correlations between lung/airway volumes on both supine and upright CT and PFT measurements in patients with COPD, and compare CT-based inspiratory/expiratory lung/lobe/airway volumes between the two positions. Methods: Forty-eight patients with COPD underwent both conventional supine and upright CT in a randomized order during inspiration and expiration breath-holds, and PFTs within 2 h. We measured the lung/lobe/airway volumes on both CT. Results: The correlation coefficients between total lung volumes on inspiratory CT in supine/standing position and PFT total lung capacity and vital capacity were 0.887/0.920 and 0.711/0.781, respectively; between total lung volumes on expiratory CT in supine/standing position and PFT functional residual capacity and residual volume, 0.676/0.744 and 0.713/0.739, respectively; and between airway volume on inspiratory CT in supine/standing position and PFT forced expiratory volume in 1 s, 0.471/0.524, respectively. Inspiratory/expiratory bilateral upper and right lower lobe, bilateral lung, and airway volumes were significantly higher in the standing than supine position (3.6-21.2% increases, all p < 0.05); however, inspiratory/expiratory right middle lobe volumes were significantly lower in the standing position (4.6%/15.9% decreases, respectively, both p < 0.001). Conclusions: Upright CT-based volumes were more correlated with PFT measurements than supine CT-based volumes in patients with COPD. Unlike other lobes and airway, inspiratory/expiratory right middle lobe volumes were significantly lower in the standing than supine position.
MeSH term(s)	Humans ; Lung/diagnostic imaging ; Pulmonary Disease, Chronic Obstructive/diagnostic imaging ; Respiratory Function Tests ; Standing Position ; Tomography, X-Ray Computed/methods
Language	English
Publishing date	2022-11-09
Publishing country	Switzerland
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	206674-9
ISSN	1423-0356 ; 0025-7931
ISSN (online)	1423-0356
ISSN	0025-7931
DOI	10.1159/000527067
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uh II Zs.138: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Centrilobular emphysema and airway dysanapsis: factors associated with low respiratory function in younger smokers.

Mochizuki, Fumi / Tanabe, Naoya / Shimada, Takafumi / Iijima, Hiroaki / Sakamoto, Ryo / Shiraishi, Yusuke / Maetani, Tomoki / Shimizu, Kaoruko / Suzuki, Masaru / Chubachi, Shotaro / Ishikawa, Hiroichi / Naito, Takashi / Kanasaki, Megumi / Masuda, Izuru / Oguma, Tsuyoshi / Sato, Susumu / Hizawa, Nobuyuki / Hirai, Toyohiro

ERJ open research

2024 Volume 10, Issue 2

Abstract: Background: Low respiratory function in young adulthood is one of the important factors in the trajectory leading to the future development of COPD, but its morphological characteristics are not well characterised.: Methods: We retrospectively ... ...

Abstract	Background: Low respiratory function in young adulthood is one of the important factors in the trajectory leading to the future development of COPD, but its morphological characteristics are not well characterised. Methods: We retrospectively enrolled 172 subjects aged 40-49 years with ≥10 pack-years smoking history who underwent lung cancer screening by computed tomography (CT) and spirometry at two Japanese hospitals. Emphysema was visually assessed according to the Fleischner Society guidelines and classified into two types: centrilobular emphysema (CLE) and paraseptal emphysema (PSE). Airway dysanapsis was assessed with the airway/lung ratio (ALR), which was calculated by the geometric mean of the lumen diameters of the 14 branching segments divided by the cube root of total lung volume on a CT scan. Results: Among the subjects, CLE and PSE were observed in 20.9% and 30.8%, respectively. The mean ALR was 0.04 and did not differ between those with and without each type of emphysema. Multivariable regression analysis models adjusted for age, sex, body mass index and smoking status indicated that CLE and a low ALR were independently associated with lower forced expiratory volume in 1 s (FEV Conclusions: CLE and airway dysanapsis on CT were independently associated with low respiratory function in younger smokers.
Language	English
Publishing date	2024-03-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2827830-6
ISSN	2312-0541
ISSN	2312-0541
DOI	10.1183/23120541.00695-2023
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Interaction of BMI and respiratory status in obstructive sleep apnea, a cross-sectional COPD study.

Hashiguchi, Mizuha Haraguchi / Chubachi, Shotaro / Yamasawa, Wakako / Otsuka, Kengo / Harada, Naoko / Miyao, Naoki / Nakamura, Hidetoshi / Asano, Koichiro / Yamaguchi, Kazuhiro / Fukunaga, Koichi

NPJ primary care respiratory medicine

2023 Volume 33, Issue 1, Page(s) 30

Abstract: This cross-sectional study of 136 patients with chronic obstructive pulmonary disease (COPD) investigated the mechanism underlying overlap syndrome, defined as coexisting COPD and obstructive sleep apnea (OSA). OSA was defined as a respiratory event ... ...

Abstract	This cross-sectional study of 136 patients with chronic obstructive pulmonary disease (COPD) investigated the mechanism underlying overlap syndrome, defined as coexisting COPD and obstructive sleep apnea (OSA). OSA was defined as a respiratory event index (REI) ≥ 5 events/h, determined using type-3 portable monitors. The mean REI was 12.8 events/h. Most participants (60.1%) had mild OSA (REI: 5-15 events/h). The REI was positively correlated with forced expiratory volume in one second (%FEV
MeSH term(s)	Humans ; Cross-Sectional Studies ; Body Mass Index ; Pulmonary Disease, Chronic Obstructive/complications ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/epidemiology ; Lung
Language	English
Publishing date	2023-08-15
Publishing country	England
Document type	Journal Article
ZDB-ID	2780812-9
ISSN	2055-1010 ; 2055-1010
ISSN (online)	2055-1010
ISSN	2055-1010
DOI	10.1038/s41533-023-00351-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Clinical features of Japanese patients with gastrointestinal long-COVID symptoms.

Yagi, Kazuma / Asakura, Takanori / Terai, Hideki / Ohgino, Keiko / Masaki, Katsunori / Namkoong, Ho / Chubachi, Shotaro / Miyata, Jun / Kawada, Ichiro / Kodama, Nobuhiro / Sakamoto, Satoshi / Umeda, Akira / Ishiguro, Takashi / Ishii, Makoto / Fukunaga, Koichi

JGH open : an open access journal of gastroenterology and hepatology

2023 Volume 7, Issue 12, Page(s) 998–1002

Abstract: Gastrointestinal (GI) long-COVID symptoms, including diarrhea and abdominal pain, have been reported in patients with long-COVID. However, the clinical features of patients with GI long-COVID symptoms remain unclear. We conducted a large-scale ... ...

Abstract	Gastrointestinal (GI) long-COVID symptoms, including diarrhea and abdominal pain, have been reported in patients with long-COVID. However, the clinical features of patients with GI long-COVID symptoms remain unclear. We conducted a large-scale prospective cohort study focusing on the clinical characteristics of patients with GI long-COVID symptoms in Japan. Among 943 COVID-19 patients, 58 patients (6.2%) had GI long-COVID symptoms. The health-related quality of life (QOL) parameters (the Short Form-8 [SF-8] and Euro Quality of Life 5 Dimensions 5 level [EQ-5D-5L]) at 12 months after diagnosis in patients with GI long-COVID symptoms were significantly lower than in those without GI long-COVID symptoms (
Language	English
Publishing date	2023-12-06
Publishing country	Australia
Document type	Journal Article
ISSN	2397-9070
ISSN (online)	2397-9070
DOI	10.1002/jgh3.13006
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Healthcare costs for hospitalized COVID-19 patients in a Japanese university hospital: a cross-sectional study.

Uno, Shunsuke / Goto, Rei / Honda, Kimiko / Tokuda, Machiko / Kamata, Hirofumi / Chubachi, Shotaro / Yamamoto, Ryo / Sato, Yukio / Homma, Koichiro / Uchida, Sho / Namkoong, Ho / Uwamino, Yoshifumi / Sasaki, Junichi / Fukunaga, Koichi / Hasegawa, Naoki

Cost effectiveness and resource allocation : C/E

2023 Volume 21, Issue 1, Page(s) 43

Abstract: Background: A health-economic evaluation related to COVID-19 is urgently needed to allocate healthcare resources efficiently; however, relevant medical cost data in Japan concerning COVID-19 are scarce.: Methods: This cross-sectional study ... ...

Abstract	Background: A health-economic evaluation related to COVID-19 is urgently needed to allocate healthcare resources efficiently; however, relevant medical cost data in Japan concerning COVID-19 are scarce. Methods: This cross-sectional study investigated the healthcare cost for hospitalized COVID-19 patients in 2021 at Keio University Hospital. We calculated the healthcare costs during hospitalization using hospital claims data and investigated the variables significantly related to the healthcare cost with multivariable analysis. Results: The median healthcare cost per patient for the analyzed 330 patients was Japanese yen (JPY) 1,304,431 (US dollars ~ 11,871) (interquartile range: JPY 968,349-1,954,093), and the median length of stay was 10 days. The median healthcare cost was JPY 798,810 for mild cases; JPY 1,113,680 for moderate I cases; JPY 1,643,909 for moderate II cases; and JPY 6,210,607 for severe cases. Healthcare costs increased by 4.0% for each additional day of hospitalization; 1.26 times for moderate I cases, 1.64 times for moderate II cases, and 1.84 times for severe cases compared to mild cases; and 2.05 times for cases involving ICU stay compared to those not staying in ICU. Conclusions: We clarified the healthcare cost for hospitalized COVID-19 patients by severity in a Japanese university hospital. These costs contribute as inputs for forthcoming health economic evaluations for strategies for preventing and treating COVID-19.
Language	English
Publishing date	2023-07-16
Publishing country	England
Document type	Journal Article
ZDB-ID	2119372-1
ISSN	1478-7547
ISSN	1478-7547
DOI	10.1186/s12962-023-00453-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Differential impacts between fat mass index and fat-free mass index on patients with COPD.

Shimada, Takashi / Chubachi, Shotaro / Otake, Shiro / Sakurai, Kaori / Sasaki, Mamoru / Iijima, Hiroaki / Tanabe, Naoya / Tanimura, Kazuya / Shimizu, Kaoruko / Shirahata, Toru / Suzuki, Masaru / Sato, Susumu / Nakamura, Hidetoshi / Asano, Koichiro / Fukunaga, Koichi

Respiratory medicine

2023 Volume 217, Page(s) 107346

Abstract: Background: Differences in the clinical impacts of fat mass index (FMI) and fat-free mass index (FFMI) remain unclear in patients with chronic obstructive pulmonary disease (COPD). We hypothesized that FMI and FFMI have different impacts on 1) emphysema ...

Abstract	Background: Differences in the clinical impacts of fat mass index (FMI) and fat-free mass index (FFMI) remain unclear in patients with chronic obstructive pulmonary disease (COPD). We hypothesized that FMI and FFMI have different impacts on 1) emphysema and 2) pulmonary function and health-related quality of life of COPD patients. Methods: Patients with COPD (n = 228), enrolled in a multicenter prospective 3-year cohort were classified into four groups based on baseline median FMI and FFMI values. Emphysema assessed as the ratio of low attenuation area to total lung volume (LAA%) on computed tomography, pulmonary function, and health-related quality of life assessed using the St. George's Respiratory Questionnaire (SGRQ) were compared. Results: The four groups had statistically significant differences in LAA%, pulmonary function, and SGRQ scores. The Low FMI Low FFMI group exhibited the highest LAA%, lowest pulmonary function, and worst SGRQ scores among the four groups. In addition, these differences were consistent over 3 years. Multivariate analysis showed that low FMI was associated with high LAA%, low inspiratory capacity/total lung capacity (IC/TLC), and carbon monoxide transfer coefficient (K Conclusion: FMI and FFMI have different effects on the clinical manifestations of COPD. Both low fat and muscle mass contributed to severe emphysema, whereas only low muscle mass contributed to worse health-related quality of life in patients with COPD.
MeSH term(s)	Humans ; Prospective Studies ; Quality of Life ; Pulmonary Disease, Chronic Obstructive/diagnostic imaging ; Lung/diagnostic imaging ; Pulmonary Emphysema/diagnostic imaging ; Emphysema ; Body Mass Index ; Body Composition/physiology
Language	English
Publishing date	2023-06-28
Publishing country	England
Document type	Multicenter Study ; Journal Article
ZDB-ID	1003348-8
ISSN	1532-3064 ; 0954-6111
ISSN (online)	1532-3064
ISSN	0954-6111
DOI	10.1016/j.rmed.2023.107346
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ui III Zs.19: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito