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  1. Article ; Online: Case 11-2022: An 80-Year-Old Woman with Pancytopenia.

    Leaf, Rebecca K / Dhami, Ranjodh S / Chun, Nancy S / Ta, Robert

    The New England journal of medicine

    2022  Volume 386, Issue 15, Page(s) 1453–1461

    MeSH term(s) Aged, 80 and over ; Female ; Humans ; Pancytopenia/etiology
    Language English
    Publishing date 2022-04-13
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMcpc2201232
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Acute renal failure after intravenous anti-D immune globulin in an adult with immune thrombocytopenic purpura.

    Chun, Nancy S / Savani, Bipin / Seder, Richard H / Taplin, Mary Ellen

    American journal of hematology

    2003  Volume 74, Issue 4, Page(s) 276–279

    Abstract: Intravenous anti-D immune globulin (anti-D IGIV) is indicated for the treatment of immune thrombocytopenic purpura (ITP) in nonsplenectomized patients who are Rh(D)-positive. Recent reports have described episodes of intravascular hemolysis (IVH) and ... ...

    Abstract Intravenous anti-D immune globulin (anti-D IGIV) is indicated for the treatment of immune thrombocytopenic purpura (ITP) in nonsplenectomized patients who are Rh(D)-positive. Recent reports have described episodes of intravascular hemolysis (IVH) and acute renal failure (ARF) after anti-D IGIV. We report the first adult patient with ITP who required and received dialysis after IVH and ARF complicating treatment with anti-D IGIV. Whether the transfusion of 2 units of Rh(D)-positive red cells, indicated for the resulting anemia, exacerbated the IVH and renal failure is unclear. Three weeks after the administration of anti-D IGIV (13 days after two hemodialysis treatments), the patient's renal function had returned to normal. This case highlights the infrequent but potentially serious side effects of anti-D IGIV and the need to monitor a patient's renal function closely if there is evidence of IVH after infusion of anti-D IGIV. If red cell transfusion is indicated, we recommend the use of Rh(D)-negative red cell products.
    MeSH term(s) Acute Kidney Injury/chemically induced ; Acute Kidney Injury/therapy ; Erythrocyte Transfusion/methods ; Female ; Hemoglobinuria/chemically induced ; Humans ; Immunoglobulins, Intravenous/adverse effects ; Immunoglobulins, Intravenous/therapeutic use ; Middle Aged ; Purpura, Thrombocytopenic, Idiopathic/complications ; Purpura, Thrombocytopenic, Idiopathic/drug therapy ; Renal Dialysis ; Rh-Hr Blood-Group System ; Rho(D) Immune Globulin/adverse effects ; Rho(D) Immune Globulin/therapeutic use
    Chemical Substances Immunoglobulins, Intravenous ; Rh-Hr Blood-Group System ; Rho(D) Immune Globulin
    Language English
    Publishing date 2003-12
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.10432
    Database MEDical Literature Analysis and Retrieval System OnLINE

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