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  1. Article ; Online: UC Davis Train-the-Trainer Primary Care Pain Management Fellowship: Addressing the Pain Management Education Gap.

    Fishman, Scott M / Copenhaver, David / Lorenzen, Kathryn / Schlingmann, Ellery / Chung, Christy

    Academic medicine : journal of the Association of American Medical Colleges

    2020  Volume 96, Issue 2, Page(s) 236–240

    Abstract: Problem: Primary care providers are responsible for the majority of pain care and opioid prescribing, but they are often inadequately trained. Training current providers to address the crisis of excessive opioid prescribing and inadequate pain ... ...

    Abstract Problem: Primary care providers are responsible for the majority of pain care and opioid prescribing, but they are often inadequately trained. Training current providers to address the crisis of excessive opioid prescribing and inadequate pain management is a substantial workforce problem that requires urgent action. This educational need is vast and requires a staged solution to amplify its effect.
    Approach: The University of California, Davis Train-the-Trainer (T3) Primary Care Pain Management Fellowship targets the most pressing topics related to pain management, including prescription drug abuse, responsible opioid prescribing, and substance abuse, as well as broad coverage of comprehensive pain management. It offers an innovative, scalable solution to address the education gap in pain management that, in part, fuels the opioid epidemic in the United States. The T3 Fellowship incorporates a competency-based curriculum and a hybrid educational model of in-person and distance-based learning and direct faculty-fellow mentoring to comprehensively train primary care providers in pain care and prepare them to train others. Since it was established in 2017, 2 cohorts (of 17 and 26 fellows) have completed the 10-month fellowship and a third cohort of 38 fellows started the program in September 2019.
    Outcomes: Pre- and postprogram surveys for the first 2 cohorts, and a 6-month postprogram survey for the first cohort, demonstrated fellows' improvement and sustained performance in pain competencies as well as increased recognition and understanding of pain and related topics.
    Next steps: If adopted by other institutions and expanded across the country, the T3 Fellowship holds potential for developing an ever-growing legion of trained professionals who will locally fill the need for effective pain management, including appropriate opioid prescribing. Advancing this model will require further economic and feasibility studies to assess costs, resources, and other variables, as well as a robust comprehensive outcomes program.
    MeSH term(s) Analgesics, Opioid/therapeutic use ; California/epidemiology ; Competency-Based Education/methods ; Education/statistics & numerical data ; Fellowships and Scholarships/statistics & numerical data ; Health Knowledge, Attitudes, Practice ; Humans ; Models, Educational ; Opioid-Related Disorders/epidemiology ; Opioid-Related Disorders/prevention & control ; Pain Management/standards ; Practice Patterns, Physicians'/ethics ; Primary Health Care/statistics & numerical data ; Program Evaluation/statistics & numerical data ; Surveys and Questionnaires ; Teacher Training/methods ; United States/epidemiology ; Universities/organization & administration
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2020-06-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 96192-9
    ISSN 1938-808X ; 1040-2446
    ISSN (online) 1938-808X
    ISSN 1040-2446
    DOI 10.1097/ACM.0000000000003554
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Magnitude and Durability of the Antibody Response to mRNA-Based Vaccination Among SARS-CoV-2 Seronegative and Seropositive Health Care Personnel.

    Ciccone, Emily J / Zhu, Deanna R / Gunderson, Annika K / Hawke, Sam / Ajeen, Rawan / Lodge, Evans K / Shook-Sa, Bonnie E / Abernathy, Haley / Garrett, Haley E / King, Elise / Alavian, Naseem / Reyes, Raquel / Taylor, Jasmine L / Beatty, Cherese / Chung, Christy / Mendoza, Carmen E / Weber, David J / Markmann, Alena J / Premkumar, Lakshmanane /
    Juliano, Jonathan J / Boyce, Ross M / Aiello, Allison E

    Open forum infectious diseases

    2024  Volume 11, Issue 1, Page(s) ofae009

    Abstract: Few studies have described changes in SARS-CoV-2 antibody levels in response to infection and vaccination at frequent intervals and over extended follow-up periods. The purpose of this study was to assess changes in SARS-CoV-2-specific antibody responses ...

    Abstract Few studies have described changes in SARS-CoV-2 antibody levels in response to infection and vaccination at frequent intervals and over extended follow-up periods. The purpose of this study was to assess changes in SARS-CoV-2-specific antibody responses among a prospective cohort of health care personnel over 18 months with up to 22 samples per person. Antibody levels and live virus neutralization were measured before and after mRNA-based vaccination with results stratified by (1) SARS-CoV-2 infection status prior to initial vaccination and (2) SARS-CoV-2 infection at any point during follow-up. We found that the antibody response to the first dose was almost 2-fold higher in individuals who were seropositive prior to vaccination, although neutralization titers were more variable. The antibody response induced by vaccination appeared to wane over time but generally persisted for 8 to 9 months, and those who were infected at any point during the study had slightly higher antibody levels over time vs those who remained uninfected. These findings underscore the need to account for SARS-CoV-2 natural infection as a modifier of vaccine responses, and they highlight the importance of frequent testing of longitudinal antibody titers over time. Together, our results provide a clearer understanding of the trajectories of antibody response among vaccinated individuals with and without prior SARS-CoV-2 infection.
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofae009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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