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Article ; Online: Serial transverse enteroplasty (STEP) in case of short bowel syndrome: did we achieve our goal? A systematic review.

Lauro, A / Santoro, A / Cirocchi, R / Michelini, M / Zorzetti, N / Cianci, M C / Bellini, M I / Casadei, C / Ripoli, M C / Coletta, R / Khouzam, S / Marino, I R / D'Andrea, V / Morabito, A

Updates in surgery

2022  Volume 74, Issue 4, Page(s) 1209–1223

Abstract: Surveys on Serial Transverse Enteroplasty (STEP) published in international literature (1 January 2003- 31 May 2021) were searched. Articles were included from 17 countries: 1/23 comparative and 22/23 cohort studies. STEP was performed on 308 patients: ... ...

Abstract Surveys on Serial Transverse Enteroplasty (STEP) published in international literature (1 January 2003- 31 May 2021) were searched. Articles were included from 17 countries: 1/23 comparative and 22/23 cohort studies. STEP was performed on 308 patients: pediatrics, adults, and mixed ages. Pediatric group included 16 studies and the adult 6. Pre-STEP residual small bowell (SB) length for pediatrics and adults ranged from 18 to 26 cm and from 30 to 70 cm, respectively. Post-STEP increased SB length for pediatrics and adults ranged between 42 and 100% and 50% and 176%, respectively. For pediatrics, enteral autonomy was reached in 32.22% of cases, parenteral nutrition (PN) dependence was 36.11%, a repeated STEP procedure (Re-STEP) was needed in 17.22%, and a bowel transplant was performed in 6.11%. In adults, enteral autonomy was achieved in 52.38%, while PN dependence was 37.1%, and no Re-STEP or transplantation were required. For the mixed group, post-STEP bowel length increased from 2 to 50 cm, enteral autonomy was obtained in 43%, PN dependence was 57%, without reported Re-STEP or transplantation. Mortality rates were between 5.55% (pediatric) and 7.14% (adults). Preoperative length with preservation of ileocecal valve represented the main predictive factors to achieve enteral autonomy.
MeSH term(s) Adult ; Child ; Digestive System Surgical Procedures/methods ; Goals ; Humans ; Parenteral Nutrition ; Retrospective Studies ; Short Bowel Syndrome/surgery ; Treatment Outcome
Language English
Publishing date 2022-07-08
Publishing country Italy
Document type Journal Article ; Systematic Review
ZDB-ID 2572692-4
ISSN 2038-3312 ; 2038-131X
ISSN (online) 2038-3312
ISSN 2038-131X
DOI 10.1007/s13304-022-01316-3
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