LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 25

Search options

  1. Article ; Online: Results from the ACI-SEC Infarction Code Registry. The ECG also exists. Response.

    Rodríguez-Leor, Oriol / Rosselló, Xavier / Cid-Álvarez, Ana Belén / Pérez de Prado, Armando

    Revista espanola de cardiologia (English ed.)

    2023  Volume 76, Issue 7, Page(s) 577

    MeSH term(s) Humans ; Infarction ; Registries ; Electrocardiography/methods
    Language Spanish
    Publishing date 2023-04-28
    Publishing country Spain
    Document type Letter
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2023.03.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Spanish Cardiac Catheterization and Coronary Intervention Registry. 28th Official Report of the Spanish Society of Cardiology Working Group on Cardiac Catheterization and Interventional Cardiology (1990-2018).

    Cid Álvarez, Ana Belén / Rodríguez Leor, Oriol / Moreno, Raúl / Pérez de Prado, Armando

    Revista espanola de cardiologia (English ed.)

    2019  Volume 72, Issue 12, Page(s) 1043–1053

    Abstract: Introduction and objectives: The Working Group on Cardiac Catheterization and Interventional Cardiology presents its annual report on the activity data for 2018.: Methods: Data were voluntarily provided by participating centers. The information was ... ...

    Abstract Introduction and objectives: The Working Group on Cardiac Catheterization and Interventional Cardiology presents its annual report on the activity data for 2018.
    Methods: Data were voluntarily provided by participating centers. The information was introduced online and was analyzed by the Steering Committee of the Working Group on Cardiac Catheterization and Interventional Cardiology.
    Results: In 2018, data were reported by 109 hospitals, 83 of these centers are public. A total of 157 632 diagnostic procedures (140 670 coronary angiograms) were performed. This year, the number of percutaneous coronary interventions increased to 72 520 (2.2% increase). There was also an increase in the complexity of coronary interventions: 10.6% in chronic total occlusions and 4.2% in unprotected left main treatment. A total of 21 261 interventional procedures were performed in the acute myocardial infarction setting, of which 91% were primary angioplasties (9.6% higher than in 2017). A total of 108398 stents were implanted, of which 93.8% were drug-eluting stents (3.5% increase). Radial approach was used in 89.4% of interventional procedures. The number of transcatheter aortic valve implantations continued to increase (25.3% increase, n=3537), as well as the number of percutaneous mitral valve repair procedures (21.4% increase, n=328), left atrial appendage closures (10.6% increase, n=644) and patent foramen ovale closures (81% increase, n=514).
    Conclusions: An increase in diagnostic and therapeutic procedures was reported in 2018, particularly in primary percutaneous coronary interventions. The use of the radial approach and complex procedures also increased. The number of structural procedures rose significantly, following the trend seen in recent years.
    MeSH term(s) Cardiac Catheterization/statistics & numerical data ; Cardiology ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/surgery ; Humans ; Percutaneous Coronary Intervention/statistics & numerical data ; Registries/statistics & numerical data ; Retrospective Studies ; Societies, Medical ; Spain
    Language Spanish
    Publishing date 2019-11-13
    Publishing country Spain
    Document type Journal Article ; Multicenter Study
    ISSN 1885-5857
    ISSN (online) 1885-5857
    DOI 10.1016/j.rec.2019.10.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Spanish Cardiac Catheterization and Coronary Intervention Registry. 27th Official Report of the Spanish Society of Cardiology Working Group on Cardiac Catheterization and Interventional Cardiology (1990-2017).

    Cid Álvarez, Ana Belén / Rodríguez Leor, Oriol / Moreno, Raúl / Pérez de Prado, Armando

    Revista espanola de cardiologia (English ed.)

    2018  Volume 71, Issue 12, Page(s) 1036–1046

    Abstract: Introduction and objectives: To present the annual report of the Working Group on Cardiac Catheterization and Interventional Cardiology on the activity data for 2017.: Methods: Data were voluntarily provided by Spanish centers with a catheterization ... ...

    Abstract Introduction and objectives: To present the annual report of the Working Group on Cardiac Catheterization and Interventional Cardiology on the activity data for 2017.
    Methods: Data were voluntarily provided by Spanish centers with a catheterization laboratory. The information was introduced online and was analyzed by the Steering Committee of the Working Group on Cardiac Catheterization and Interventional Cardiology.
    Results: In 2017, data were reported by 107 hospitals, of which 82 are public. A total of 154 218 diagnostic procedures (138 448 coronary angiograms) were performed (2.2% increase vs 2016). The use of intracoronary diagnostic techniques significantly increased, especially that of pressure wire (23.2% vs 2016, n=7003). In 2017, the number of percutaneous coronary interventions rose to 70 928 (3.2% increase), of which 21 395 interventional procedures were performed in the acute myocardial infarction setting. A total of 105 529 stents were implanted, of which 90.3% were drug-eluting stents (6% increase). Radial access was used in 85.7% of diagnostic procedures and in 88.4% of interventional procedures. The number of transcatheter aortic valve implantations continued to increase (28.2% increase, n=2821), as did the number of left atrial appendage closures (14.8% increase, n=582) and percutaneous mitral valve repair procedures (14.1% increase, n=270).
    Conclusions: Diagnostic and therapeutic procedures in acute myocardial infarction increased in 2017. The use of the radial approach and drug-eluting stents also increased in therapeutic procedures. The number of structural procedures rose significantly compared with previous years.
    MeSH term(s) Aged ; Cardiac Catheterization/statistics & numerical data ; Cardiology ; Coronary Artery Disease/surgery ; Female ; Humans ; Incidence ; Male ; Percutaneous Coronary Intervention/statistics & numerical data ; Postoperative Complications/epidemiology ; Registries ; Retrospective Studies ; Societies, Medical ; Spain/epidemiology ; Stents ; Survival Rate/trends
    Language Spanish
    Publishing date 2018-10-05
    Publishing country Spain
    Document type Journal Article ; Multicenter Study
    ISSN 1885-5857
    ISSN (online) 1885-5857
    DOI 10.1016/j.rec.2018.09.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Prognostic impact of renal function trajectories in patients with STEMI and kidney dysfunction undergoing primary percutaneous coronary intervention: An analysis of ten years all-comers registry.

    Tasende Rey, Pablo / Otero García, Oscar / Cid Álvarez, Ana Belén / Juskova, Mària / Álvarez Álvarez, Belén / García Acuña, José María / Agra Bermejo, Rosa / Rigueiro Veloso, Pedro / López Otero, Diego / Sanmartín Pena, Juan Carlos / Trillo Nouche, Ramiro / González-Juanatey, José R

    Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese

    2022  Volume 66, Page(s) 1–10

    Abstract: Background: Renal dysfunction in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) indicates a poor long-term prognosis. However, the prognostic value of the improvement or ... ...

    Abstract Background: Renal dysfunction in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) indicates a poor long-term prognosis. However, the prognostic value of the improvement or stabilisation of renal function during follow-up has not yet been assessed. This study aimed to investigate the long-term predictive impact of the improvement or stabilisation of renal function after one year of follow-up in patients with STEMI undergoing pPCI with renal dysfunction at discharge.
    Methods: This prospective, single-centre cohort study included 2170 consecutive patients with STEMI who underwent pPCI. The glomerular filtration rate (GFR) was determined at hospital discharge and one-year follow-up. The median clinical follow-up was 72 months.
    Results: Among the 2004 patients, 393 (19.6%) had a GFR <60 ml/min, and 1611 (80.4%) had a GFR ≥ 60 ml/min at discharge. Among patients with GFR <60 ml/min, data at one-year follow-up were available for 342. Of these patients, 127 (32%) showed improvement in renal function (defined as improvement in the Kidney Disease Improving Global Outcomes (KDIGO) chronic kidney disease (CKD) classification), 47 (12%) showed worsening of renal function (defined as worsening of the KDIGO CKD classification), and 168 (43%) showed no category changes. Improvement or stabilisation of GFR at one year of follow-up was associated with a reduction of major adverse cardiovascular events (MACE) [HR 0.51, 95% CI: 0.35-0.75, p = 0.001] and all-cause mortality [HR 0.54, 95% CI: 0.34-0.84, p = 0.007] during follow-up.
    Conclusions: The improvement or stabilisation of renal function at one-year follow-up in patients with STEMI and renal dysfunction is associated with a better long-term prognosis.
    MeSH term(s) Cohort Studies ; Humans ; Kidney/physiology ; Percutaneous Coronary Intervention/adverse effects ; Prognosis ; Prospective Studies ; Registries ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/epidemiology ; Risk Factors ; ST Elevation Myocardial Infarction/complications ; ST Elevation Myocardial Infarction/surgery
    Language English
    Publishing date 2022-05-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2215027-4
    ISSN 2241-5955 ; 1109-9666
    ISSN (online) 2241-5955
    ISSN 1109-9666
    DOI 10.1016/j.hjc.2022.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Analysis of the management of ST-segment elevation myocardial infarction in Spain. Results from the ACI-SEC Infarction Code Registry.

    Rodríguez-Leor, Oriol / Cid-Álvarez, Ana Belén / Pérez de Prado, Armando / Rosselló, Xavier / Ojeda, Soledad / Serrador, Ana / López-Palop, Ramón / Martín-Moreiras, Javier / Rumoroso, José Ramón / Cequier, Ángel / Ibáñez, Borja / Cruz-González, Ignacio / Romaguera, Rafael / Raposeiras, Sergio / Moreno, Raúl

    Revista espanola de cardiologia (English ed.)

    2022  Volume 75, Issue 8, Page(s) 669–680

    Abstract: Introduction and objectives: ST-segment elevation myocardial infarction (STEMI) networks should guarantee STEMI care with good clinical results and within the recommended time parameters. There is no contemporary information on the performance of these ... ...

    Abstract Introduction and objectives: ST-segment elevation myocardial infarction (STEMI) networks should guarantee STEMI care with good clinical results and within the recommended time parameters. There is no contemporary information on the performance of these networks in Spain. The objective of this study was to analyze the clinical characteristics of patients, times to reperfusion, characteristics of the intervention performed, and 30-day mortality.
    Methods: Prospective, observational, multicenter registry of consecutive patients treated in 17 STEMI networks in Spain (83 centers with the Infarction Code), between April 1 and June 30, 2019.
    Results: A total of 5401 patients were attended (mean age, 64±13 years; 76.9% male), of which 4366 (80.8%) had confirmed STEMI. Of these, 87.5% were treated with primary angioplasty, 4.4% with fibrinolysis, and 8.1% did not receive reperfusion. In patients treated with primary angioplasty, the time between symptom onset and reperfusion was 193 [135-315] minutes and the time between first medical contact and reperfusion was 107 [80-146] minutes. Overall 30-day mortality due to STEMI was 7.9%, while mortality in patients treated with primary angioplasty was 6.8%.
    Conclusions: Most patients with STEMI were treated with primary angioplasty. In more than half of the patients, the time from first medical contact to reperfusion was <120 minutes. Mortality at 30 days was relatively low.
    MeSH term(s) Aged ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Registries ; ST Elevation Myocardial Infarction/diagnosis ; ST Elevation Myocardial Infarction/epidemiology ; ST Elevation Myocardial Infarction/therapy ; Spain/epidemiology
    Language Spanish
    Publishing date 2022-01-20
    Publishing country Spain
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2021.12.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Predictive Value of the SYNTAX Score in Culprit and Nonculprit Vessel Disease. Response.

    Galvão Braga, Carlos / Cid-Álvarez, Ana Belén / Redondo Diéguez, Alfredo / Trillo-Nouche, Ramiro

    Revista espanola de cardiologia (English ed.)

    2017  Volume 70, Issue 7, Page(s) 618–619

    Language Spanish
    Publishing date 2017-07
    Publishing country Spain
    Document type Letter
    ISSN 1885-5857
    ISSN (online) 1885-5857
    DOI 10.1016/j.rec.2017.02.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Sex-related differences in long-term mortality and heart failure in a contemporary cohort of patients with NSTEACS. The cardiochus-HSUJ registry.

    Álvarez Álvarez, Belén / Abou Jokh Casas, Charigan / Agra Bermejo, Rosa / Cordero, Alberto / Cid Álvarez, Ana Belén / Rodriguez Mañero, Moisés / Bouzas Cruz, Noelia / García Acuña, José María / Salgado Barreiro, Angel / González-Juanatey, José R

    European journal of internal medicine

    2020  Volume 81, Page(s) 26–31

    Abstract: Introduction and objectives: There is insufficient data regarding sex-related prognostic differences in patients with a non-ST elevation acute coronary syndrome (NSTEACS). We performed a sex-specific analysis of cardiovascular outcomes after NSTEACS ... ...

    Abstract Introduction and objectives: There is insufficient data regarding sex-related prognostic differences in patients with a non-ST elevation acute coronary syndrome (NSTEACS). We performed a sex-specific analysis of cardiovascular outcomes after NSTEACS using a large contemporary cohort of patients from two tertiary hospitals.
    Methods: This work is a retrospective analysis from a prospective registry, that included 5,686 consecutive NSTEACS patients from two Spanish University hospitals between the years 2005 and 2017. We performed a propensity score matching to obtain a well-balanced subset of individuals with the same clinical characteristics, resulting in 3,120 patients. Cox regression models performed survival analyses once the proportional risk test was verified.
    Results: Among the study participants, 1,572 patients (27.6%) were women. The mean follow-up was 60.0 months (standard deviation of 32 months). Women had a higher risk of cardiovascular mortality compared with men (OR (Odds ratio) 1.27, CI (confidence interval) 95% 1.08-1.49), heart failure (HF) hospitalization (OR 1.39, CI 95% 1.18-1.63) and risk of all-cause mortality (OR 1.10, CI 95% 1.08-1.49). After a propensity score matching, female gender was associated with a significant reduction in the risk of total mortality (OR 0.77, CI 95% 0.65-0.90) with a similar risk of cardiovascular mortality (OR 0.86, CI 0.71-1.03) and HF hospitalization (OR 0.92, CI 95% 0.68-1.23). After baseline adjustment, the risk of all-cause mortality and cardiovascular mortality was lower in women, whereas the risk of HF remained similar among sexes.
    Conclusions: In a contemporary cohort of patients with NSTEACS, women are at similar risk of developing early and late HF admissions, and have better survival compared with men, with a lower risk of all-cause mortality and cardiovascular mortality. The implementation of NSTEACS guideline recommendations in women, including early revascularization, seems to be accompanied by improved early and long-term prognosis.
    MeSH term(s) Acute Coronary Syndrome ; Cohort Studies ; Female ; Heart Failure ; Humans ; Male ; Registries ; Retrospective Studies ; Risk Factors
    Language English
    Publishing date 2020-06-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2020.06.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Prognostic impact of left ventricular ejection fraction recovery in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: analysis of an 11-year all-comers registry.

    Otero-García, Oscar / Cid-Álvarez, Ana Belén / Juskova, Mària / Álvarez-Álvarez, Belén / Tasende-Rey, Pablo / Gude-Sampedro, Francisco / García-Acuña, José María / Agra-Bermejo, Rosa / López-Otero, Diego / Sanmartín-Pena, Juan Carlos / Martínez-Monzonís, Amparo / Trillo-Nouche, Ramiro / González-Juanatey, José R

    European heart journal. Acute cardiovascular care

    2021  Volume 10, Issue 8, Page(s) 898–908

    Abstract: Aims: Left ventricular ejection fraction (LVEF) recovery after an ST-segment elevation myocardial infarction (STEMI) identifies a group of patients with a better prognosis. However, the association between long-term outcomes and LVEF recovery among ... ...

    Abstract Aims: Left ventricular ejection fraction (LVEF) recovery after an ST-segment elevation myocardial infarction (STEMI) identifies a group of patients with a better prognosis. However, the association between long-term outcomes and LVEF recovery among patients with STEMI undergoing primary percutaneous coronary intervention (PCI) has not yet been well investigated. Our study aims to detect differences in long-term all-cause and cardiovascular mortality between patients who recover LVEF at 1-year post-PCI and those who do not, and search for predictors of LVEF recovery.
    Methods and results: This is a retrospective, single-centre study of 2170 consecutive patients admitted for STEMI in which primary PCI is performed. LVEF was determined at admission and at 1-year follow-up. The primary outcomes were long-term all-cause and cardiovascular mortality. Among the 2168 patients with baseline LVEF data, 822 (38%) had a LVEF < 50% and 1346 (62%) ≥ 50%. Among those with LVEF < 50%, LVEF data at 1-year were available in 554, and 299 (54.0%) presented with complete recovery (LVEF ≥ 50%). LVEF recovery was associated with a reduction in long-term all-cause and cardiovascular mortality (P < 0.0001). Female sex, treatment with ACEIs, lower creatinine levels, infarct-related artery different from the left main or left anterior descendent artery, and absence of prior ischaemic heart disease were independently associated with LVEF recovery.
    Conclusions: Nearly 40% of patients with STEMI undergoing primary PCI presented with LVEF depression at hospital admission. Among them, LVEF recovery at 1-year occurred in more than 50% and was independently associated with a significant decrease in long-term all-cause and cardiovascular mortality.
    MeSH term(s) Female ; Humans ; Percutaneous Coronary Intervention ; Prognosis ; Registries ; Retrospective Studies ; ST Elevation Myocardial Infarction/diagnosis ; ST Elevation Myocardial Infarction/surgery ; Stroke Volume ; Ventricular Function, Left
    Language English
    Publishing date 2021-07-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2663340-1
    ISSN 2048-8734 ; 2048-8726
    ISSN (online) 2048-8734
    ISSN 2048-8726
    DOI 10.1093/ehjacc/zuab058
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Short-term mortality differs between men and women according to the presence of previous cardiovascular disease: Insights from a nationwide STEMI cohort.

    González-Del-Hoyo, Maribel / Rodríguez-Leor, Oriol / Cid-Álvarez, Ana Belén / de Prado, Armando Pérez / Ojeda, Soledad / Serrador, Ana / López-Palop, Ramón / Martín-Moreiras, Javier / Rumoroso, José Ramón / Cequier, Ángel / Ibáñez, Borja / Cruz-González, Ignacio / Romaguera, Rafael / Raposeiras-Roubin, Sergio / Moreno, Raúl / Rossello, Xavier

    International journal of cardiology

    2022  Volume 367, Page(s) 90–98

    Abstract: Background: Sex and prior cardiovascular disease (CVD) are known independent prognostic factors following an ST-elevation myocardial infarction (STEMI). We aimed to examine whether the association between sex and 30-day mortality differ according to the ...

    Abstract Background: Sex and prior cardiovascular disease (CVD) are known independent prognostic factors following an ST-elevation myocardial infarction (STEMI). We aimed to examine whether the association between sex and 30-day mortality differ according to the presence of previous CVD in STEMI patients.
    Methods: Prospective, observational, multicentre registry of consecutive patients managed in 17 STEMI networks in Spain (83 centres), between April and June 2019. Unadjusted and adjusted logistic regression models assessed the association of 30-day mortality with sex and prior CVD status, as well as their interaction.
    Results: Among 4366 patients (mean age 63.7 ± 13.0 years; 78% male), there were 337 (8.1%) deaths within the first 30 days. There was an association between crude 30-day mortality and sex (women 10.4% vs. men 7.4%, p = 0.003), and prior CVD (CVD 13.7% vs non-CVD 6.8%, p < 0.001). After adjustment for potential confounding, neither sex nor prior CVD were apparently associated with mortality. Nevertheless, we found a significant sex-CVD interaction (p-interaction = 0.006), since women were at lower risk than men in the subset of patients with prior CVD (OR = 0.30, 95%CI = 0.12-0.80) but not in those without CVD (OR = 1.17, 95%CI = 0.79-1.74).
    Conclusions: Women as well as patients with prior CVD have an increased crude risk of 30-day mortality. However, sex-related differences in short term mortality are modulated by the interaction with CVD in STEMI patients. Compared to men, women had a similar prognosis in the subset of patients without CVD, whereas they were associated with a lower risk of mortality among those with prior CVD after adjusting for other prognostic factors.
    MeSH term(s) Aged ; Cardiovascular Diseases/diagnosis ; Cohort Studies ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Prospective Studies ; Risk Factors ; ST Elevation Myocardial Infarction/diagnosis ; Sex Factors
    Language English
    Publishing date 2022-08-25
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2022.08.036
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: A Prospective, Multicenter, Real-World Registry of Coronary Lithotripsy in Calcified Coronary Arteries: The REPLICA-EPIC18 Study.

    Rodriguez-Leor, Oriol / Cid-Alvarez, Ana Belen / Lopez-Benito, Maria / Gonzalo, Nieves / Vilalta, Victoria / Diarte de Miguel, Jose Antonio / López, Leticia Fernandez / Jurado-Roman, Alfonso / Diego, Alejandro / Oteo, Juan Francisco / Cuellas, Carlos / Trillo, Ramiro / Travieso, Alejandro / Alfonso, Fernando / Carrillo, Xavier / Vegas-Valle, José Miguel / Cortes-Villar, Carlos / Pascual, Isaac / Muñoz Camacho, Juan Francisco /
    Flores, Xacobe / Vera-Vera, Silvio / Moreu, Jose / Barreira de Sousa, Gilles / Martí, David / Jimenez-Mazuecos, Jesus / Fuertes, Monica / Ocaranza, Raymundo / de la Torre Hernandez, Jose Maria / Lozano, Fernando / Solana Martinez, Santiago G / Gómez-Lara, Josep / Perez de Prado, Armando

    JACC. Cardiovascular interventions

    2024  Volume 17, Issue 6, Page(s) 756–767

    Abstract: Background: Intravascular lithotripsy (IVL) has demonstrated effectiveness in the treatment of calcified lesions in selected patients with stable coronary disease.: Objectives: The authors sought to assess the performance of coronary IVL in calcified ...

    Abstract Background: Intravascular lithotripsy (IVL) has demonstrated effectiveness in the treatment of calcified lesions in selected patients with stable coronary disease.
    Objectives: The authors sought to assess the performance of coronary IVL in calcified coronary lesions in a real-life, all comers, setting.
    Methods: The REPLICA-EPIC18 study prospectively enrolled consecutive patients treated with IVL in 26 centers in Spain. An independent core laboratory performed the angiographic analysis and event adjudication. The primary effectiveness endpoint assessed procedural success (successful IVL delivery, final diameter stenosis <20%, and absence of in-hospital major adverse cardiovascular events [MACE]). The primary safety endpoint measured freedom from MACE at 30 days. A predefined substudy compared outcomes between acute coronary syndrome (ACS) and chronic coronary syndrome (CCS) patients.
    Results: A total of 426 patients (456 lesions) were included, 63% of the patients presenting with ACS. IVL delivery was successful in 99% of cases. Before IVL, 49% of lesions were considered undilatable. The primary effectiveness endpoint was achieved in 66% of patients, with similar rates among CCS patients (68%) and ACS patients (65%). Likewise, there were no significant differences in angiographic success after IVL between CCS and ACS patients. The rate of MACE at 30 days (primary safety endpoint) was 3% (1% in CCS and 5% in ACS patients [P = 0.073]).
    Conclusions: Coronary IVL proved to be a feasible and safe procedure in a "real-life" setting, effectively facilitating stent implantation in severely calcified lesions. Patients with ACS on admission showed similar angiographic success rates but showed a trend toward higher 30-day MACE compared with patients with CCS. (REPLICA-EPIC18 study [Registry of Coronary Lithotripsy in Spain]; NCT04298307).
    MeSH term(s) Humans ; Coronary Vessels ; Prospective Studies ; Treatment Outcome ; Heart ; Lithotripsy/adverse effects ; Acute Coronary Syndrome ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/therapy ; Vascular Calcification/diagnostic imaging ; Vascular Calcification/therapy
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2023.12.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top