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  1. AU="Cifuentes-Diaz, Carmen"
  2. AU="Alvim, Ricardo G"
  3. AU="Barron II, Joseph C"
  4. AU="Godin, Shea-Lee"
  5. AU="Leng, Chengcai"
  6. AU="Hyslop, Brian W"
  7. AU="Suzanne Fischer"
  8. AU="Aboelata, Noha"
  9. AU="Chiang, Sarah N"
  10. AU="Wessel, Kristin M"
  11. AU="Wilson, Jenna M"
  12. AU="Goines, Paula"
  13. AU=Ippolito Mariachiara AU=Ippolito Mariachiara
  14. AU="Jose Chauca"
  15. AU="Asih, Puji B S"
  16. AU="Dsane-Selby, Lydia"
  17. AU="Tolossa, Tadesse"
  18. AU="Erdal Bedir"

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  1. Artikel: Differential impacts of

    Cifuentes-Diaz, Carmen / Canali, Giorgia / Garcia, Marta / Druart, Mélanie / Manett, Taylor / Savariradjane, Mythili / Guillaume, Camille / Le Magueresse, Corentin / Goutebroze, Laurence

    Frontiers in neuroscience

    2023  Band 17, Seite(n) 1100121

    Abstract: Over the last decade, a large variety of alterations of ... ...

    Abstract Over the last decade, a large variety of alterations of the
    Sprache Englisch
    Erscheinungsdatum 2023-01-30
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2023.1100121
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Pyk2 Regulates MAMs and Mitochondrial Dynamics in Hippocampal Neurons.

    López-Molina, Laura / Fernández-Irigoyen, Joaquín / Cifuentes-Díaz, Carmen / Alberch, Jordi / Girault, Jean-Antoine / Santamaría, Enrique / Ginés, Silvia / Giralt, Albert

    Cells

    2022  Band 11, Heft 5

    Abstract: Pyk2 is a non-receptor tyrosine kinase enriched in hippocampal neurons, which can be activated by calcium-dependent mechanisms. In neurons, Pyk2 is mostly localised in the cytosol and dendritic shafts but can translocate to spines and/or to the nucleus. ... ...

    Abstract Pyk2 is a non-receptor tyrosine kinase enriched in hippocampal neurons, which can be activated by calcium-dependent mechanisms. In neurons, Pyk2 is mostly localised in the cytosol and dendritic shafts but can translocate to spines and/or to the nucleus. Here, we explore the function of a new localisation of Pyk2 in mitochondria-associated membranes (MAMs), a subdomain of ER-mitochondria surface that acts as a signalling hub in calcium regulation. To test the role of Pyk2 in MAMs' calcium transport, we used full Pyk2 knockout mice (Pyk2
    Mesh-Begriff(e) Animals ; Calcium ; Focal Adhesion Kinase 2/metabolism ; Hippocampus/metabolism ; Mice ; Mitochondrial Dynamics ; Neurons/metabolism
    Chemische Substanzen Focal Adhesion Kinase 2 (EC 2.7.10.2) ; Ptk2b protein, mouse (EC 2.7.10.2) ; Calcium (SY7Q814VUP)
    Sprache Englisch
    Erscheinungsdatum 2022-03-01
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells11050842
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: A human dynein heavy chain mutation impacts cortical progenitor cells causing developmental defects, reduced brain size and altered brain architecture.

    Romero, Delfina M / Zaidi, Donia / Cifuentes-Diaz, Carmen / Maillard, Camille / Grannec, Gael / Selloum, Mohammed / Birling, Marie-Christine / Bahi-Buisson, Nadia / Francis, Fiona

    Neurobiology of disease

    2023  Band 180, Seite(n) 106085

    Abstract: Dynein heavy chain (DYNC1H1) mutations can either lead to severe cerebral cortical malformations, or alternatively may be associated with the development of spinal muscular atrophy with lower extremity predominance (SMA-LED). To assess the origin of such ...

    Abstract Dynein heavy chain (DYNC1H1) mutations can either lead to severe cerebral cortical malformations, or alternatively may be associated with the development of spinal muscular atrophy with lower extremity predominance (SMA-LED). To assess the origin of such differences, we studied a new Dync1h1 knock-in mouse carrying the cortical malformation p.Lys3334Asn mutation. Comparing with an existing neurodegenerative Dync1h1 mutant (Legs at odd angles, Loa, p.Phe580Tyr/+), we assessed Dync1h1's roles in cortical progenitor and especially radial glia functions during embryogenesis, and assessed neuronal differentiation. p.Lys3334Asn /+ mice exhibit reduced brain and body size. Embryonic brains show increased and disorganized radial glia: interkinetic nuclear migration occurs in mutants, however there are increased basally positioned cells and abventricular mitoses. The ventricular boundary is disorganized potentially contributing to progenitor mislocalization and death. Morphologies of mitochondria and Golgi apparatus are perturbed in vitro, with different effects also in Loa mice. Perturbations of neuronal migration and layering are also observed in p.Lys3334Asn /+ mutants. Overall, we identify specific developmental effects due to a severe cortical malformation mutation in Dync1h1, highlighting the differences with a mutation known instead to primarily affect motor function.
    Mesh-Begriff(e) Humans ; Mice ; Animals ; Dyneins/genetics ; Cytoplasmic Dyneins/genetics ; Cytoplasmic Dyneins/metabolism ; Muscular Atrophy, Spinal/genetics ; Organ Size ; Mutation/genetics ; Brain/metabolism ; Stem Cells
    Chemische Substanzen Dyneins (EC 3.6.4.2) ; Cytoplasmic Dyneins (EC 3.6.4.2)
    Sprache Englisch
    Erscheinungsdatum 2023-03-16
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1211786-9
    ISSN 1095-953X ; 0969-9961
    ISSN (online) 1095-953X
    ISSN 0969-9961
    DOI 10.1016/j.nbd.2023.106085
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Ultrastructural Evidence for Oxytocin and Oxytocin Receptor at the Spinal Dorsal Horn: Mechanism of Nociception Modulation.

    Martínez-Lorenzana, Guadalupe / Palma-Tirado, Lourdes / Cifuentes-Diaz, Carmen / González-Hernández, Abimael / Condés-Lara, Miguel

    Neuroscience

    2021  Band 475, Seite(n) 117–126

    Abstract: Oxytocin is a hypothalamic neuropeptide involved in the inhibition of nociception transmission at spinal dorsal horn (SDH) level (the first station where the incoming peripheral signals is modulated). Electrophysiological, behavioral, and pharmacological ...

    Abstract Oxytocin is a hypothalamic neuropeptide involved in the inhibition of nociception transmission at spinal dorsal horn (SDH) level (the first station where the incoming peripheral signals is modulated). Electrophysiological, behavioral, and pharmacological data strongly support the role of this neuropeptide and its receptor (the oxytocin receptor, OTR) as a key endogenous molecule with analgesic properties. Briefly, current data showed that oxytocin release from the hypothalamus induces OTR activation at the SDH, inducing selective inhibition of the nociceptive Aδ- and C-fibers (probably peptidergic) activity, but not the activity of proprioceptive fibers (i.e. Aβ-fibers). The above inhibition could be a direct presynaptic mechanism, or a mechanism mediated by GABAergic interneurons. However, the exact anatomical localization of oxytocin and OTR remains unclear. In this context, the present study set out to analyze the role of OTRs, GABAergic cells and CGRP fibers in the SDH in rats by using electron microscopy. Ultrastructural analyses of the SDH tissue show that: (i) oxytocin and OTR are found in asymmetrical synapsis; (ii) OTR is found in GABAergic interneurons (near unmyelinated fibers), CGRPergic fibers and glial cells; (iii) whereas oxytocin is present in supraspinal descending projection fibers. These anatomical data strongly support the notion that oxytocin released at the SDH could presynaptically inhibit the nociceptive input from the peripheral primary afferent fibers. This inhibitory action could be direct or use a GABA interneuron. Furthermore, our findings that OTR is exhibited in glial tissue at the SDH requires further exploration in nociception assays.
    Mesh-Begriff(e) Animals ; Nerve Fibers, Unmyelinated ; Nociception ; Oxytocin ; Posterior Horn Cells ; Rats ; Receptors, Oxytocin ; Spinal Cord Dorsal Horn
    Chemische Substanzen Receptors, Oxytocin ; oxytocin receptor, rat ; Oxytocin (50-56-6)
    Sprache Englisch
    Erscheinungsdatum 2021-09-14
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 196739-3
    ISSN 1873-7544 ; 0306-4522
    ISSN (online) 1873-7544
    ISSN 0306-4522
    DOI 10.1016/j.neuroscience.2021.09.004
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  5. Artikel ; Online: Anatomical and ultrastructural study of PRAF2 expression in the mouse central nervous system.

    Cifuentes-Diaz, Carmen / Marullo, Stefano / Doly, Stéphane

    Brain structure & function

    2016  Band 221, Heft 8, Seite(n) 4169–4185

    Abstract: Prenylated Rab acceptor family, member 2 (PRAF2) is a four transmembrane domain protein of 19 kDa that is highly expressed in particular areas of mammalian brains. PRAF2 is mostly found in the endoplasmic reticulum (ER) of neurons where it plays the role ...

    Abstract Prenylated Rab acceptor family, member 2 (PRAF2) is a four transmembrane domain protein of 19 kDa that is highly expressed in particular areas of mammalian brains. PRAF2 is mostly found in the endoplasmic reticulum (ER) of neurons where it plays the role of gatekeeper for the GB1 subunit of the GABA
    Mesh-Begriff(e) Animals ; Brain/cytology ; Brain/metabolism ; HEK293 Cells ; Humans ; Mice ; Mitochondria/metabolism ; Mitochondria/ultrastructure ; Neurons/metabolism ; Neurons/ultrastructure ; Spinal Cord/metabolism ; Synapses/metabolism ; Synapses/ultrastructure ; Ventral Tegmental Area/metabolism ; Ventral Tegmental Area/ultrastructure ; Vesicular Transport Proteins/metabolism
    Chemische Substanzen Rabac1 protein, mouse ; Vesicular Transport Proteins
    Sprache Englisch
    Erscheinungsdatum 2016-11
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 2273162-3
    ISSN 1863-2661 ; 1863-2653
    ISSN (online) 1863-2661
    ISSN 1863-2653
    DOI 10.1007/s00429-015-1159-8
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: hVFL3/CCDC61 is a component of mother centriole subdistal appendages required for centrosome cohesion and positioning.

    Pizon, Véronique / Gaudin, Noémie / Poteau, Marion / Cifuentes-Diaz, Carmen / Demdou, Roland / Heyer, Vincent / Reina San Martin, Bernardo / Azimzadeh, Juliette

    Biology of the cell

    2019  Band 112, Heft 1, Seite(n) 22–37

    Abstract: Background: The centrosome regulates cell spatial organisation by controlling the architecture of the microtubule (MT) cytoskeleton. Conversely, the position of the centrosome within the cell depends on cytoskeletal networks it helps organizing. In ... ...

    Abstract Background: The centrosome regulates cell spatial organisation by controlling the architecture of the microtubule (MT) cytoskeleton. Conversely, the position of the centrosome within the cell depends on cytoskeletal networks it helps organizing. In mammalian cells, centrosome positioning involves a population of MT stably anchored at centrioles, the core components of the centrosome. An MT-anchoring complex containing the proteins ninein and Cep170 is enriched at subdistal appendages (SAP) that decorate the older centriole (called mother centriole) and at centriole proximal ends. Here, we studied the role played at the centrosome by hVFL3/CCDC61, the human ortholog of proteins required for anchoring distinct sets of cytoskeletal fibres to centrioles in unicellular eukaryotes.
    Results: We show that hVFL3 co-localises at SAP and at centriole proximal ends with components of the MT-anchoring complex, and physically interacts with Cep170. Depletion of hVFL3 increased the distance between mother and daughter centrioles without affecting the assembly of a filamentous linker that tethers the centrioles and contains the proteins rootletin and C-Nap1. When the linker was disrupted by inactivating C-Nap1, hVFL3-depletion exacerbated centriole splitting, a phenotype also observed following depletion of other SAP components. This supported that hVFL3 is required for SAP function, which we further established by showing that centrosome positioning is perturbed in hVFL3-depleted interphase cells. Finally, we found that hVFL3 is an MT-binding protein.
    Conclusions and significance: Together, our results support that hVFL3 is required for anchoring MT at SAP during interphase and ensuring proper centrosome cohesion and positioning. The role of the VFL3 family of proteins thus appears to have been conserved in evolution despite the great variation in the shape of centriole appendages in different eukaryotic species.
    Mesh-Begriff(e) Animals ; CRISPR-Cas Systems ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Cell Line ; Centrioles/metabolism ; Centrioles/ultrastructure ; Centrosome/metabolism ; Centrosome/ultrastructure ; Cilia/ultrastructure ; Cytoskeletal Proteins/metabolism ; Cytoskeleton/ultrastructure ; Humans ; Microscopy, Electron ; Microtubules/metabolism ; Microtubules/ultrastructure ; RNA, Small Interfering ; Tubulin/metabolism
    Chemische Substanzen Carrier Proteins ; Cytoskeletal Proteins ; RNA, Small Interfering ; Tubulin
    Sprache Englisch
    Erscheinungsdatum 2019-12-11
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 245745-3
    ISSN 1768-322X ; 0399-0311 ; 0248-4900
    ISSN (online) 1768-322X
    ISSN 0399-0311 ; 0248-4900
    DOI 10.1111/boc.201900038
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  7. Artikel ; Online: Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia.

    Uzquiano, Ana / Cifuentes-Diaz, Carmen / Jabali, Ammar / Romero, Delfina M / Houllier, Anne / Dingli, Florent / Maillard, Camille / Boland, Anne / Deleuze, Jean-François / Loew, Damarys / Mancini, Grazia M S / Bahi-Buisson, Nadia / Ladewig, Julia / Francis, Fiona

    Cell reports

    2019  Band 28, Heft 6, Seite(n) 1596–1611.e10

    Abstract: Apical radial glia (aRGs) are predominant progenitors during corticogenesis. Perturbing their function leads to cortical malformations, including subcortical heterotopia (SH), characterized by the presence of neurons below the cortex. EML1/Eml1 mutations ...

    Abstract Apical radial glia (aRGs) are predominant progenitors during corticogenesis. Perturbing their function leads to cortical malformations, including subcortical heterotopia (SH), characterized by the presence of neurons below the cortex. EML1/Eml1 mutations lead to SH in patients, as well as to heterotopic cortex (HeCo) mutant mice. In HeCo mice, some aRGs are abnormally positioned away from the ventricular zone (VZ). Thus, unraveling EML1/Eml1 function will clarify mechanisms maintaining aRGs in the VZ. We pinpoint an unknown EML1/Eml1 function in primary cilium formation. In HeCo aRGs, cilia are shorter, less numerous, and often found aberrantly oriented within vesicles. Patient fibroblasts and human cortical progenitors show similar defects. EML1 interacts with RPGRIP1L, a ciliary protein, and RPGRIP1L mutations were revealed in a heterotopia patient. We also identify Golgi apparatus abnormalities in EML1/Eml1 mutant cells, potentially upstream of the cilia phenotype. We thus reveal primary cilia mechanisms impacting aRG dynamics in physiological and pathological conditions.
    Mesh-Begriff(e) Adaptor Proteins, Signal Transducing/genetics ; Adolescent ; Animals ; Cells, Cultured ; Cilia/genetics ; Cilia/pathology ; Classical Lissencephalies and Subcortical Band Heterotopias/genetics ; Classical Lissencephalies and Subcortical Band Heterotopias/pathology ; Female ; Golgi Apparatus/genetics ; Golgi Apparatus/pathology ; HEK293 Cells ; Humans ; Male ; Mice ; Microtubule-Associated Proteins/genetics ; Mutation ; Pregnancy
    Chemische Substanzen Adaptor Proteins, Signal Transducing ; Eml1 protein, human ; Microtubule-Associated Proteins ; RPGRIP1L protein, human
    Sprache Englisch
    Erscheinungsdatum 2019-08-20
    Erscheinungsland United States
    Dokumenttyp Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2649101-1
    ISSN 2211-1247 ; 2211-1247
    ISSN (online) 2211-1247
    ISSN 2211-1247
    DOI 10.1016/j.celrep.2019.06.096
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Schwannomin-interacting Protein 1 Isoform IQCJ-SCHIP1 Is a Multipartner Ankyrin- and Spectrin-binding Protein Involved in the Organization of Nodes of Ranvier.

    Martin, Pierre-Marie / Cifuentes-Diaz, Carmen / Devaux, Jérôme / Garcia, Marta / Bureau, Jocelyne / Thomasseau, Sylvie / Klingler, Esther / Girault, Jean-Antoine / Goutebroze, Laurence

    The Journal of biological chemistry

    2016  Band 292, Heft 6, Seite(n) 2441–2456

    Abstract: The nodes of Ranvier are essential regions for action potential conduction in myelinated fibers. They are enriched in multimolecular complexes composed of voltage-gated Nav and Kv7 channels associated with cell adhesion molecules. Cytoskeletal proteins ... ...

    Abstract The nodes of Ranvier are essential regions for action potential conduction in myelinated fibers. They are enriched in multimolecular complexes composed of voltage-gated Nav and Kv7 channels associated with cell adhesion molecules. Cytoskeletal proteins ankyrin-G (AnkG) and βIV-spectrin control the organization of these complexes and provide mechanical support to the plasma membrane. IQCJ-SCHIP1 is a cytoplasmic protein present in axon initial segments and nodes of Ranvier. It interacts with AnkG and is absent from nodes and axon initial segments of βIV-spectrin and AnkG mutant mice. Here, we show that IQCJ-SCHIP1 also interacts with βIV-spectrin and Kv7.2/3 channels and self-associates, suggesting a scaffolding role in organizing nodal proteins. IQCJ-SCHIP1 binding requires a βIV-spectrin-specific domain and Kv7 channel 1-5-10 calmodulin-binding motifs. We then investigate the role of IQCJ-SCHIP1
    Mesh-Begriff(e) Animals ; Ankyrins/metabolism ; Biopolymers/metabolism ; COS Cells ; Carrier Proteins/chemistry ; Carrier Proteins/metabolism ; Chlorocebus aethiops ; Mice ; Mice, Mutant Strains ; Motor Activity ; Peripheral Nervous System/physiology ; Peripheral Nervous System/ultrastructure ; Ranvier's Nodes/metabolism
    Chemische Substanzen Ankyrins ; Biopolymers ; Carrier Proteins ; SCHIP1 protein, mouse ; spectrin-binding proteins
    Sprache Englisch
    Erscheinungsdatum 2016-12-15
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1074/jbc.M116.758029
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Apport d'un modèle murin de neuropathie démyélinisante inflammatoire au développement de thérapeutiques: caractérisations fonctionnelle et morphologique.

    Benoit, Evelyne / Cifuentes-Diaz, Carmen / Molgó, Jordi

    Journal de la Societe de biologie

    2007  Band 200, Heft 4, Seite(n) 293–300

    Abstract: To finalize a mouse model of inflammatory demyelinating neuropathy, we injected a solution containing a bovine pancreas protease, active at neutral pH, in the perineural space of the mouse left sciatic nerve (a nerve consisting of myelinated axons). The ... ...

    Titelübersetzung A mouse model of inflammatory demyelinating neuropathy for the development of therapeutics: electrophysiological and morphological characterizations.
    Abstract To finalize a mouse model of inflammatory demyelinating neuropathy, we injected a solution containing a bovine pancreas protease, active at neutral pH, in the perineural space of the mouse left sciatic nerve (a nerve consisting of myelinated axons). The locomotive behaviour of animals was daily followed and, between 3 and 45 days after the injection, the sciatic nerves were removed from animals, studied using classical electrophysiological techniques and then, at least for some of them, examined using conventional microscopy. The right sciatic nerve, which did not receive a perineural injection, is a very good control, because it comes from the same animal as the left sciatic nerve which underwent the injection. The results obtained show that, under our experimental conditions, i) a demyelinisation of nerve fibres can be detected between 6 and 15 days after the injection of protease, resulting in a defective axonal conduction of action potentials, and ii) 45 days are sufficient to restore a normal axonal conduction. These results are interesting since they indicate that this mouse model can be used to test the ability of new pharmaceutical agents to counteract the defective nerve conduction of action potentials arising after an axonal demyelinisation, in the perspective of developing new useful molecules for the treatment of inflammatory demyelinating neuropathies.
    Mesh-Begriff(e) Animals ; Axons/physiology ; Cattle ; Demyelinating Diseases/physiopathology ; Demyelinating Diseases/therapy ; Disease Models, Animal ; Electrophysiology ; Inflammation/physiopathology ; Mice ; Pancreas/enzymology ; Peptide Hydrolases/metabolism ; Sciatic Nerve/pathology ; Sciatic Nerve/physiopathology
    Chemische Substanzen Peptide Hydrolases (EC 3.4.-)
    Sprache Französisch
    Erscheinungsdatum 2007-07-03
    Erscheinungsland France
    Dokumenttyp English Abstract ; Journal Article
    ZDB-ID 1476234-1
    ISSN 1760-6128 ; 1295-0661
    ISSN (online) 1760-6128
    ISSN 1295-0661
    DOI 10.1051/jbio:2006034
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease.

    Giralt, Albert / de Pins, Benoit / Cifuentes-Díaz, Carmen / López-Molina, Laura / Farah, Amel Thamila / Tible, Marion / Deramecourt, Vincent / Arold, Stefan T / Ginés, Silvia / Hugon, Jacques / Girault, Jean-Antoine

    Experimental neurology

    2018  Band 307, Seite(n) 62–73

    Abstract: Pyk2 is a ... ...

    Abstract Pyk2 is a Ca
    Mesh-Begriff(e) Aged, 80 and over ; Alzheimer Disease/enzymology ; Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Animals ; Cerebral Cortex/enzymology ; Cerebral Cortex/pathology ; Disease Models, Animal ; Female ; Focal Adhesion Kinase 2/biosynthesis ; Focal Adhesion Kinase 2/genetics ; Gene Expression Regulation, Enzymologic/physiology ; Hippocampus/enzymology ; Hippocampus/pathology ; Humans ; Locomotion/physiology ; Male ; Maze Learning/physiology ; Mice ; Mice, Transgenic ; Plaque, Amyloid/enzymology ; Plaque, Amyloid/genetics ; Plaque, Amyloid/pathology
    Chemische Substanzen Focal Adhesion Kinase 2 (EC 2.7.10.2) ; Ptk2b protein, mouse (EC 2.7.10.2)
    Sprache Englisch
    Erscheinungsdatum 2018-05-24
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 207148-4
    ISSN 1090-2430 ; 0014-4886
    ISSN (online) 1090-2430
    ISSN 0014-4886
    DOI 10.1016/j.expneurol.2018.05.020
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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