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  1. AU="Cilhoroz, Burak T"
  2. AU=Bacher Michael
  3. AU="Fujiyama, Shunichiro"
  4. AU="Ling, Xiaocui"
  5. AU="Chiu, I"
  6. AU="Bergsma, Tessa"
  7. AU="Nicitra, Emanuele"
  8. AU=Strauss Eric J AU=Strauss Eric J
  9. AU="Andy C. Y. Tse"
  10. AU=Diel J
  11. AU="Teper, Alejandro"
  12. AU="Daniel Cisterna"
  13. AU="Barré-Sinoussi, Françoise"
  14. AU="Siracusa, Massimiliano"
  15. AU="Mishra, Vipin Kumar"
  16. AU=Martinez Victor D.
  17. AU="Seol, Myung Do"
  18. AU="Sato, Keiyu"
  19. AU="Go, Ji Young"
  20. AU="Zhao, Bingjian"
  21. AU="Ringeisen, Bradley R"
  22. AU=Sciascia Savino
  23. AU="Capito, Carmen"
  24. AU=Osman Mahasin

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  1. Artikel ; Online: PTSD symptom clusters and cardiovascular responses to stress: Reactivity and recovery.

    Lee, Sharon Y / Park, Crystal L / Cilhoroz, Burak T / Pescatello, Linda S

    Journal of psychosomatic research

    2022  Band 161, Seite(n) 110996

    Abstract: Objective: Posttraumatic stress disorder (PTSD) symptoms are associated with high blood pressure (BP) and decreased heart rate variability (HRV) at rest and in response to acute stress. Unique contributions of PTSD symptom clusters to cardiovascular ... ...

    Abstract Objective: Posttraumatic stress disorder (PTSD) symptoms are associated with high blood pressure (BP) and decreased heart rate variability (HRV) at rest and in response to acute stress. Unique contributions of PTSD symptom clusters to cardiovascular responses to stress are rarely investigated. This study tested whether PTSD-related arousal/reactivity drives relationships of higher PTSD symptoms with higher BP and lower HRV during rest, reactivity (stressor-induced change from baseline), and recovery.
    Methods: Using a cross-sectional observational design, we enrolled 84 trauma-exposed community adults (83% female; 68% White; M
    Results: Arousal/reactivity was not associated with BP or HRV reactivity but associated with a higher low (LF) to high (HF) frequency (HF) ratio (LF/HF) during recovery reflecting sympathetic predominance. During the stressor, more avoidance and intrusion were associated with increased diastolic blood pressure (DBP) from baseline; more avoidance was associated with parasympathetic predominance (lower LF/HF); and more negative cognitions/mood was associated with decreased systolic blood pressure (SBP), DBP, and LF from baseline. During recovery, more intrusion and negative cognitions/mood were associated with increased SBP from baseline; less negative cognitions/mood was associated with sympathetic predominance (higher LF/HF).
    Conclusions: PTSD symptom clusters demonstrated differential relationships with SBP, DBP, and HRV during reactivity and recovery. Findings may inform targeted PTSD symptom reduction interventions for disrupting links between PTSD and CVD risk.
    Mesh-Begriff(e) Adult ; Autonomic Nervous System Diseases ; Cross-Sectional Studies ; Female ; Heart Rate/physiology ; Humans ; Hypertension ; Male ; Stress Disorders, Post-Traumatic ; Syndrome
    Sprache Englisch
    Erscheinungsdatum 2022-07-29
    Erscheinungsland England
    Dokumenttyp Journal Article ; Observational Study ; Research Support, N.I.H., Extramural
    ZDB-ID 80166-5
    ISSN 1879-1360 ; 0022-3999
    ISSN (online) 1879-1360
    ISSN 0022-3999
    DOI 10.1016/j.jpsychores.2022.110996
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Safety protocols in an exercise facility result in no detectable sars-CoV2 spread: A case study.

    Cilhoroz, Burak T / DeRuisseau, Lara R

    Physiological reports

    2021  Band 9, Heft 14, Seite(n) e14967

    Abstract: Coronavirus 2019 (COVID-19) disease has been a public health emergency of international concern with millions of confirmed cases globally. Closed environments with reduced ventilation contribute to the spread of COVID-19, including superspreading events. ...

    Abstract Coronavirus 2019 (COVID-19) disease has been a public health emergency of international concern with millions of confirmed cases globally. Closed environments with reduced ventilation contribute to the spread of COVID-19, including superspreading events. Exercising in closed places further increases the risk for transmission. Therefore, many fitness facilities were closed as part of mandated shutdowns early in the pandemic. Evidence-based safety protocols have now emerged and substantially reduce the risk of transmission. We report three positive cases of SARS-CoV-2 identified at a Dojo exercise facility in Manlius, NY, at three distinct time points. All cases were present in the Dojo 2 days prior to symptoms, a time period considered to be highly infectious. The safety protocols included universal mask wearing (no valves), multiple high-efficiency particulate air (HEPA) filters, and reduced capacity which resulted in no known spread of COVID-19.
    Mesh-Begriff(e) Air Filters ; COVID-19/transmission ; Disinfection ; Evidence-Based Medicine ; Exercise ; Fitness Centers ; Humans ; Masks ; Pandemics ; Personal Protective Equipment ; Risk ; Safety ; Ventilation
    Sprache Englisch
    Erscheinungsdatum 2021-07-19
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2724325-4
    ISSN 2051-817X ; 2051-817X
    ISSN (online) 2051-817X
    ISSN 2051-817X
    DOI 10.14814/phy2.14967
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: The vascular response to acute hyperglycaemia: What is the role of exercise capacity?

    Heckel, Andrew R / Cilhoroz, Burak T / Rosenberg, Jared

    The Journal of physiology

    2021  Band 600, Heft 4, Seite(n) 711–713

    Mesh-Begriff(e) Acute Disease ; Blood Glucose ; Exercise/physiology ; Exercise Tolerance ; Humans ; Hyperglycemia
    Chemische Substanzen Blood Glucose
    Sprache Englisch
    Erscheinungsdatum 2021-06-26
    Erscheinungsland England
    Dokumenttyp Journal Article ; Comment
    ZDB-ID 3115-x
    ISSN 1469-7793 ; 0022-3751
    ISSN (online) 1469-7793
    ISSN 0022-3751
    DOI 10.1113/JP281813
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Uc I Zs.65: Hefte anzeigen Standort:
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  4. Artikel ; Online: Metabolic syndrome: Operational definitions and aerobic and resistance training benefits on physical and metabolic health in children and adolescents.

    Leister, Kyle R / Cilhoroz, Burak T / Rosenberg, Jared / Brown, Elise C / Kim, Joon Young

    Diabetes & metabolic syndrome

    2022  Band 16, Heft 6, Seite(n) 102530

    Abstract: Background: The variation in parameters for childhood metabolic syndrome (MetS) has hindered the development of a consensus for the diagnostic criteria in this group. Despite these inconsistencies, it is accepted that exercise can ameliorate the ... ...

    Abstract Background: The variation in parameters for childhood metabolic syndrome (MetS) has hindered the development of a consensus for the diagnostic criteria in this group. Despite these inconsistencies, it is accepted that exercise can ameliorate the deleterious effects of MetS. However, direct comparison between aerobic versus resistance exercise on MetS symptomology in adolescents is lacking.
    Aim: Aim of this review was to discuss controversies associated with current MetS operation definitions in adolescents and present a review summarizing longitudinal studies relevant to the influence of aerobic and resistance training on children with MetS.
    Methods: Reviews of PubMed and Web of Science were conducted to identify literature focusing on the influence of aerobic and resistance training on children with MetS. Selected manuscripts featured longitudinal research only.
    Results: A universally accepted definition of MetS for the pediatric population has yet to be established. As such, consensus regarding diagnostic criteria for MetS among children is lacking despite the presence of various descriptions in the literature. Though studies support the importance of aerobic and resistance exercise to combat comorbidities associated with MetS, longitudinal studies investigating the benefits of each exercise type among adolescents are limited and inconsistent.
    Conclusion: An improved understanding of the impact of aerobic and resistance training on children with MetS is clinically relevant because it may facilitate more appropriate exercise recommendations for children with MetS. Additional large cohort studies are warranted to determine optimal exercise type.
    Mesh-Begriff(e) Adolescent ; Child ; Cohort Studies ; Exercise ; Exercise Therapy ; Humans ; Metabolic Syndrome/epidemiology ; Resistance Training
    Sprache Englisch
    Erscheinungsdatum 2022-06-08
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2273766-2
    ISSN 1878-0334 ; 1871-4021
    ISSN (online) 1878-0334
    ISSN 1871-4021
    DOI 10.1016/j.dsx.2022.102530
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: The Relationship between Postexercise Hypotension and Heart Rate Variability before and after Exercise Training.

    Cilhoroz, Burak T / Zaleski, Amanda / Taylor, Beth / Fernandez, Antonio B / Santos, Lucas P / Vonk, Thijs / Thompson, Paul D / Pescatello, Linda S

    Journal of cardiovascular development and disease

    2023  Band 10, Heft 2

    Abstract: Because data are scarce, we examined the relationship between postexercise hypotension (PEH) and heart rate variability (HRV) before and after aerobic exercise training among adults with hypertension. Participants completed a 12 w aerobic training ... ...

    Abstract Because data are scarce, we examined the relationship between postexercise hypotension (PEH) and heart rate variability (HRV) before and after aerobic exercise training among adults with hypertension. Participants completed a 12 w aerobic training program. Before and after training, they performed a peak graded exercise stress test (GEST) and nonexercise control (CONTROL) and were left attached to an ambulatory BP monitor. Prior to CONTROL, HRV was measured supine for 5 min using a 12-lead electrocardiogram (ECG). The participants (
    Sprache Englisch
    Erscheinungsdatum 2023-02-03
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2777082-5
    ISSN 2308-3425 ; 2308-3425
    ISSN (online) 2308-3425
    ISSN 2308-3425
    DOI 10.3390/jcdd10020064
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Arterial stiffness and augmentation index are associated with balance function in young adults.

    Cilhoroz, Burak T / Heckel, Andrew R / DeBlois, Jacob P / Keller, Allison / Sosnoff, Jacob J / Heffernan, Kevin S

    European journal of applied physiology

    2022  Band 123, Heft 4, Seite(n) 891–899

    Abstract: Objective: Arterial stiffness and pulsatile central hemodynamics have been shown to affect various aspects of physical function, such as exercise capacity, gait speed, and motor control. The aim of this study was to examine the potential association ... ...

    Abstract Objective: Arterial stiffness and pulsatile central hemodynamics have been shown to affect various aspects of physical function, such as exercise capacity, gait speed, and motor control. The aim of this study was to examine the potential association between arterial stiffness and balance function in healthy younger men and women.
    Methods: 112 participants (age = 21 ± 4 years, n = 78 women) underwent measures of arterial stiffness, pulsatile central hemodynamics, balance function and physical fitness in this cross-sectional study. Postural sway was measured in triplicate while participants stood on a foam surface with their eyes closed for 20 s. The average total center of pressure path length from the three trials was used for analysis. Measures of vascular function were estimated using an oscillometric blood pressure device while at rest and included pulse wave velocity (PWV), augmentation index (AIx), and pulse pressure amplification. Measures of physical fitness used as covariates in statistical models included handgrip strength determined from a handgrip dynamometer, lower-body flexibility assessed using a sit-and-reach test, estimated maximal aerobic capacity (VO
    Results: The results from linear regression indicated that after considering sex, mean arterial pressure, body fat, estimated VO
    Conclusion: Vascular function is associated with balance function in young adults independent of physical fitness. Increased arterial stiffness may negatively influence balance, while wave reflections may be protective for balance.
    Mesh-Begriff(e) Male ; Humans ; Female ; Young Adult ; Adolescent ; Adult ; Vascular Stiffness/physiology ; Pulse Wave Analysis/methods ; Cross-Sectional Studies ; Hand Strength ; Blood Pressure
    Sprache Englisch
    Erscheinungsdatum 2022-12-23
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 124793-1
    ISSN 1439-6327 ; 1432-1025 ; 0301-5548 ; 1439-6319
    ISSN (online) 1439-6327 ; 1432-1025
    ISSN 0301-5548 ; 1439-6319
    DOI 10.1007/s00421-022-05116-w
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  7. Artikel: Exploration of cerebral hemodynamic pathways through which large artery function affects neurovascular coupling in young women.

    Cilhoroz, Burak T / DeBlois, Jacob P / Lefferts, Wesley K / Keller, Allison P / Pagan Lassalle, Patricia / Meyer, Michelle L / Stoner, Lee / Heffernan, Kevin S

    Frontiers in cardiovascular medicine

    2022  Band 9, Seite(n) 914439

    Abstract: Background: The interactions between large artery function and neurovascular coupling (NVC) are emerging as important contributors to cognitive health. Women are disproportionally affected by Alzheimer's disease and related dementia later in life. ... ...

    Abstract Background: The interactions between large artery function and neurovascular coupling (NVC) are emerging as important contributors to cognitive health. Women are disproportionally affected by Alzheimer's disease and related dementia later in life. Understanding large artery correlates of NVC in young women may help with preservation of cognitive health with advancing age.
    Purpose: To explore the association between large artery function, NVC and cognitive performance in young women.
    Methods: Vascular measurements were made in 61 women (21 ± 4 yrs) at rest and during a cognitive challenge (Stroop task). Transcranial Doppler was used to measure left middle cerebral artery (MCA) maximum velocity (V
    Results: MCA V
    Conclusions: NVC was associated with cognitive function in young women. Carotid artery function assessed as carotid compliance and carotid reactivity may contribute to optimal NVC in young women through increased blood flow delivery and reduced blood flow pulsatility.
    Sprache Englisch
    Erscheinungsdatum 2022-08-12
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2022.914439
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: FURIN variant associations with postexercise hypotension are intensity and race dependent.

    Cilhoroz, Burak T / Schifano, Elizabeth D / Panza, Gregory A / Ash, Garrett I / Corso, Lauren / Chen, Ming-Hui / Deshpande, Ved / Zaleski, Amanda / Farinatti, Paulo / Santos, Lucas P / Taylor, Beth A / O'Neill, Rachel J / Thompson, Paul D / Pescatello, Linda S

    Physiological reports

    2019  Band 7, Heft 3, Seite(n) e13952

    Abstract: FURIN is a proprotein convertase subtilisin/kexin enzyme important in pro-renin receptor processing, and FURIN (furin, paired basic amino acid cleaving enzyme) variants are involved in multiple aspects of blood pressure (BP) regulation. Therefore, we ... ...

    Abstract FURIN is a proprotein convertase subtilisin/kexin enzyme important in pro-renin receptor processing, and FURIN (furin, paired basic amino acid cleaving enzyme) variants are involved in multiple aspects of blood pressure (BP) regulation. Therefore, we examined associations among FURIN variants and the immediate blood pressure (BP) response to bouts of aerobic exercise, termed postexercise hypotension (PEH). Obese (30.9 ± 3.6 kg
    Mesh-Begriff(e) Adolescent ; Adult ; Black or African American/genetics ; Bicycling ; Blood Pressure/genetics ; Case-Control Studies ; Exercise ; Female ; Furin/genetics ; Genetic Association Studies ; Genetic Predisposition to Disease ; Humans ; Hypertension/ethnology ; Hypertension/genetics ; Hypertension/physiopathology ; Hypotension/ethnology ; Hypotension/genetics ; Hypotension/physiopathology ; Male ; Middle Aged ; Obesity/ethnology ; Obesity/genetics ; Obesity/physiopathology ; Phenotype ; Polymorphism, Single Nucleotide ; Risk Factors ; Time Factors ; White People/genetics ; Young Adult
    Chemische Substanzen FURIN protein, human (EC 3.4.21.75) ; Furin (EC 3.4.21.75)
    Sprache Englisch
    Erscheinungsdatum 2019-02-01
    Erscheinungsland United States
    Dokumenttyp Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2724325-4
    ISSN 2051-817X ; 2051-817X
    ISSN (online) 2051-817X
    ISSN 2051-817X
    DOI 10.14814/phy2.13952
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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