Artikel ; Online: Long-term echographic surveillance of elevated choroidal nevi.
American journal of ophthalmology
2013 Band 156, Heft 3, Seite(n) 438–443.e1
Abstract: Purpose: To report the outcomes of choroidal nevi monitoring and to compare the detection of ultrasonographic hollowness, a risk factor of malignant transformation, from a B-scan with results from an A-scan examination.: Design: Retrospective cohort ... ...
| Abstract | Purpose: To report the outcomes of choroidal nevi monitoring and to compare the detection of ultrasonographic hollowness, a risk factor of malignant transformation, from a B-scan with results from an A-scan examination. Design: Retrospective cohort study. Methods: Standardized A- and B-scan echography and ophthalmoscopy in 358 consecutive patients with median age 69 years and baseline choroidal nevus higher or lower than 1.5 mm in 51 (14%) and 307 (86%) eyes, respectively. Results: No growth or change in echographic or ophthalmoscopic features were found in 307 nevi with a median elevation of 0.9 mm (range, 0.7 to 1.5 mm) and a median follow-up of 6 years (range, 4 to 9 years). After 2 to 6 years, decreased internal reflectivity on standardized A-scan and ultrasonographic hollowness on B-scan were detected in 7 (18%) of 38 initially highly reflective choroidal nevi (thickness, 1.98 ± 0.37 mm); 2 (5%) nevi grew into melanoma 15 years after the first observation. Of 13 choroidal nevi (thickness, 2.75 ± 0.66 mm), with initial atypical medium to high reflectivity on standardized A-scan (100%) and hollowness on B-scan (85%), 6 (46%) were plaqued 6 to 15 months later because of the presence of multiple risk factors. Conclusions: No changes in thickness or echographic features of choroidal nevi elevated up to 1.5 mm were recorded during the follow-up period. In initially typical choroidal nevi higher than 1.5 mm, strong agreement was detected between decreased reflectivity on standardized A-scan and ultrasonographic hollowness on B-scan found after up to 15 years of stability. The vast majority of choroidal nevi with initial atypical standardized A-scan features showed ultrasonographic hollowness. |
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| Mesh-Begriff(e) | Aged ; Aged, 80 and over ; Cell Transformation, Neoplastic/pathology ; Cell Transformation, Neoplastic/ultrastructure ; Choroid Neoplasms/diagnostic imaging ; Choroid Neoplasms/pathology ; Diagnostic Techniques, Ophthalmological ; Female ; Follow-Up Studies ; Humans ; Male ; Melanoma/pathology ; Melanoma/ultrastructure ; Middle Aged ; Nevus, Pigmented/diagnostic imaging ; Nevus, Pigmented/pathology ; Ophthalmoscopy ; Retrospective Studies ; Risk Factors ; Ultrasonography |
| Sprache | Englisch |
| Erscheinungsdatum | 2013-09 |
| Erscheinungsland | United States |
| Dokumenttyp | Journal Article |
| ZDB-ID | 80030-2 |
| ISSN | 1879-1891 ; 0002-9394 |
| ISSN (online) | 1879-1891 |
| ISSN | 0002-9394 |
| DOI | 10.1016/j.ajo.2013.04.010 |
| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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